Armed with a healthy dose of wit and curiosity, medical journalist Randi Hutter Epstein reveals the “invigorating history” (Nature) of hormones and the age-old quest to control them through the back rooms, basements, and labs where endocrinology began.

    It’s not only inevitable and frightening, it’s intriguing and fascinating–especially today, when science continues to make ever more stunning advances in the investigation of the oldest and darkest of mysteries. To discover the how and why of death, unearth its roots, and expose the mechanics of its grim handiwork is, at least in some sense, to master it. And in the process, if a criminal can be caught or closure found, so much the better.Enter Robert Mann, forensic anthropologist, deputy scientific director of the U.S. government’s Central Identification Laboratory, and, some might say, the Sherlock Holmes of death detectives. When the dead reveal some of their most sensational, macabre, and poignant tales, more often than not it’s Mann who’s been listening. Now, in this remarkable casebook, he offers an in-depth behind-the-scenes portrait of his sometimes gruesome, frequently dangerous, and always compelling profession. In cases around the world, Mann has been called upon to unmask killers with nothing but the bones of their victims to guide him, draw out clues that restore identities to the nameless dead, recover remains thought to be hopelessly lost, and piece together the events that can unlock the truth behind the most baffling deaths.The infamous 9/11 terror attacks, which killed thousands; the unplanned killing that inaugurated serial murderer Jeffrey Dahmer’s grisly spree; mysterious military fatalities from World War II to the Cold War to Vietnam, including the amazing case of the Vietnam War’s Unknown Soldier–all the fascinating stories are here, along with photos from the author’s personal files. Mystery hangings, mass graves, errant body parts, actual skeletons in closets, and a host of homicides steeped in bizarre clues and buried secrets–they’re all in a day’s work for one dedicated detective whose job begins when a life ends.From the Hardcover edition.

    Ranging from the depths of the ocean to the most arid corners of the land, Caspar Henderson captures the beauty and bizzareness of the many living forms we thought we knew and some we could never have contemplated, inviting us to better imagine the precarious world we inhabit.A witty, vivid blend of cutting edge natural history and meditative reflections, The Book of Barely Imagined Beings is infectious and celebratory about the sheer ingenuity and variety of life.

    Like other immigrant groups before them, they showed up with little money but with an intense work ethic and an unshakeable belief in the promise of the United States. Many of them lived in a world outside the law, working in a shadow economy overseen by the ruthless gangs that ruled the narrow streets of New York’s Chinatown.The figure who came to dominate this Chinese underworld was a middle-aged grandmother known as Sister Ping. Her path to the American dream began with an unusual business run out of a tiny noodle store on Hester Street. From her perch above the shop, Sister Ping ran a full-service underground bank for illegal Chinese immigrants. But her real business-a business that earned an estimated $40 million-was smuggling people. As a “snakehead,” she built a complex—and often vicious—global conglomerate, relying heavily on familial ties, and employing one of Chinatown's most violent gangs to protect her power and profits. Like an underworld CEO, Sister Ping created an intricate smuggling network that stretched from Fujian Province to Hong Kong to Burma to Thailand to Kenya to Guatemala to Mexico. Her ingenuity and drive were awe-inspiring both to the Chinatown community—where she was revered as a homegrown Don Corleone—and to the law enforcement officials who could never quite catch her. Indeed, Sister Ping’s empire only came to light in 1993 when the Golden Venture, a ship loaded with 300 undocumented immigrants, ran aground off a Queens beach. It took New York’s fabled “Jade Squad” and the FBI nearly ten years to untangle the criminal network and home in on its unusual mastermind.THE SNAKEHEAD is a panoramic tale of international intrigue and a dramatic portrait of the underground economy in which America’s twelve million illegal immigrants live. Based on hundreds of interviews, Patrick Radden Keefe’s sweeping narrative tells the story not only of Sister Ping, but of the gangland gunslingers who worked for her, the immigration and law enforcement officials who pursued her, and the generation of penniless immigrants who risked death and braved a 17,000 mile odyssey so that they could realize their own version of the American dream. The Snakehead offers an intimate tour of life on the mean streets of Chinatown, a vivid blueprint of organized crime in an age of globalization and a masterful exploration of the ways in which illegal immigration affects us all.www.doubleday.com

    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    In 1828, when New York City purchased this narrow, two-mile-long island in the East River, it was called Blackwell’s Island. There, over the next hundred years, the city would send its insane, indigent, sick, and criminal. Told through the gripping voices of Blackwell’s inhabitants, as well as the period’s city officials, reformers, and journalists (including the famous Nellie Bly), Stacy Horn has crafted a compelling and chilling narrative.  Damnation Island recreates what daily life was like on the island, what politics shaped it, and what constituted charity and therapy in the nineteenth century. Throughout the book, we return to the extraordinary Blackwell’s missionary Reverend French, champion of the forgotten, as he ministers to these inmates, battles the bureaucratic mazes of the Corrections Department and a corrupt City Hall, testifies at salacious trials, and in his diary wonders about man’s inhumanity to man.   For history fans, and for anyone interested in the ways we care for the least fortunate among us, Damnation Island is an eye-opening look at a closed and secretive world. With a tale that is exceedingly relevant today, Horn shows us how far we’ve come—and how much work still remains.

    Then a forensic scientist leads police to the peeled skin from two boiled hands--and the fingerprints that will crack the case.The murder weapon was smashed to smithereensA man was killed by a blow from a bottle. Now, determined investigator carefully puts the pieces of glass back together to catch a kiler--and to carry out a crime of his own...What the corpse revealedOnce detectives solved crimes with shoe leather and a gun. Now they use DNA samples, blood splatters, microbes and psychological profilings. This extraordinary book, through details drawn from some of the most baffling cases of the last fifty years, shows how a new generation fo real-life crime busters is catching stalkers, poisoners, mass murderers, and assassins--through the astounding art of forensic science.

    What is it like to try to heal the body when the mind is under attack? In this book, Dr. Allan Ropper and Brian Burrell take the reader behind the scenes at Harvard Medical School's neurology unit to show how a seasoned diagnostician faces down bizarre, life-altering afflictions. Like Alice in Wonderland, Dr. Ropper inhabits a world where absurdities abound:• A figure skater whose body has become a ticking time-bomb • A salesman who drives around and around a traffic rotary, unable to get off • A college quarterback who can't stop calling the same play • A child molester who, after falling on the ice, is left with a brain that is very much dead inside a body that is very much alive • A mother of two young girls, diagnosed with ALS, who has to decide whether a life locked inside her own head is worth livingHow does one begin to treat such cases, to counsel people whose lives may be changed forever? How does one train the next generation of clinicians to deal with the moral and medical aspects of brain disease? Dr. Ropper and his colleague answer these questions by taking the reader into a rarified world where lives and minds hang in the balance.

    Drawing on her own fieldwork in the Mediterranean, Africa, Asia, and beyond, archeologist Brenna Hassett explores the long history of urbanization through revolutionary changes written into the bones of the people who lived it.For every major new lifestyle, another way of dying appeared. From the "cradle of civilization" in the ancient Near East to the dawn of agriculture on the American plains, skeletal remains and fossil teeth show evidence of shorter lives, rotten teeth, and growth interrupted. The scarring on human skeletons reveals that getting too close to animals had some terrible consequences, but so did getting too close to too many other people.Each chapter of Built on Bones moves forward in time, discussing in depth humanity's great urban experiment. Hassett explains the diseases, plagues, epidemics, and physical dangers we have unwittingly unleashed upon ourselves throughout the urban past--and, as the world becomes increasingly urbanized, what the future holds for us. In a time when "Paleo" lifestyles are trendy and so many of us feel the pain of the city daily grind, this book asks the critical question: Was it worth it?

    Global warming and associated climate change exists - but the role of humans in that change is entirely debatable. A little-known aspect of modern climate science is that the warming of the global atmosphere-ocean system over the last 100 years, even if entirely human-caused, has progressed at a rate that reduces the threat of future warming by 50% compared to the climate model projections. To the extent warming is partly natural (a possibility even the IPCC acknowledges), the future threat is reduced even further. This, by itself, should be part of the debate over energy policy – but it isn’t. Why? The news media, politicians, bureaucrats, rent-seekers, government funding agencies, and a “scientific-technological elite” (as President Eisenhower called it) have collaborated to spread what amounts to fake climate news. Exaggerated climate claims appear on a daily basis, sucking the air out of more reasoned discussions of the scientific evidence which are too boring for a populace increasingly addicted to climate change porn. Upon close examination it is found that the "97% of climate scientists agree" meme is inaccurate, misleading, and useless for decision-making; human causation of warming is simply assumed by the vast majority of climate researchers. In contrast to what many have been taught, there have been no obvious changes in severe weather, including hurricanes, tornadoes, droughts or floods. Despite an active 2018 wildfire season, there has actually been a long-term decrease in wildfire activity, although that will change if forest management practices are not implemented. Proxy evidence of past temperature and Arctic sea ice changes suggest warming and sea ice decline over the last 50 years or so is not out of the ordinary, and partly or even mostly natural. The Antarctic ice sheet isn't collapsing, but remains stable. The human component of sea level rise is shown to be, at most, only 1 inch per 30 years (25% of the observed rate of rise); and the latest evidence is that more CO2 dissolved in ocean water will be good for marine life, not harmful. Admittedly, continued emissions of CO2 from fossil fuel burning can be expected to cause (and probably has caused) some of our recent warming. But the Paris Agreement, even if extended through the end of the 21st Century, will have no measurable effect on global temperatures because the governments of the world realize humanity will depend upon fossil fuels for decades to come. Despite news reports and politicians' proclamations, international agreements to reduce CO2 emissions are all economic pain for no observable climate gain. What government-mandated reliance on expensive and impractical energy sources will do is increase energy poverty, and poverty kills. This downside to illusory efforts to “Save the Earth” is already being experienced in the UK and elsewhere. If people are genuinely concerned about humanity thriving, they must reject global warming alarmism. In terms of environmental regulation, the end result of the U.S. EPA's Endangerment Finding will be reduced prosperity for all, and climate gain for none. The good news is that there is no global warming crisis, and this book will inform citizens and help guide governments toward decisions which benefit the most people while doing the least harm.

    In the early 1800s, women were dying in large numbers from treatable diseases because they avoided receiving medical care. Examinations performed by male doctors were often demeaning and even painful. In addition, women faced stigma from illness—a diagnosis could greatly limit their ability to find husbands, jobs or be received in polite society.Motivated by personal loss and frustration over inadequate medical care, Elizabeth Blackwell, Elizabeth Garrett Anderson and Sophia Jex-Blake fought for a woman’s place in the male-dominated medical field. For the first time ever, Women in White Coats tells the complete history of these three pioneering women who, despite countless obstacles, earned medical degrees and paved the way for other women to do the same. Though very different in personality and circumstance, together these women built women-run hospitals and teaching colleges—creating for the first time medical care for women by women.With gripping storytelling based on extensive research and access to archival documents, Women in White Coats tells the courageous history these women made by becoming doctors, detailing the boundaries they broke of gender and science to reshape how we receive medical care today.

    In telling this fascinating story, M. William Phelps also paints a vivid portrait of early-twentieth-century New England.

    Pleasant Animal Shelter"Benjamin writes with love and sensitivity about caring for pets 'adopted' from a shelter."--Publishers Weekly"...a solid training program...a great book."--Job Michael Evans, Dog Fancy"Why a book like this has never before been written is beyond me. It is an invaluable guide to rehabilitating those myriad unfortunate dogs which have either never had a home or have been shuttled from one owner to another, losing confidence, trust and self-esteem every step of the way. It is an absolute must for every owner who wants his second-hand dog to regain the ability to become the warm, loving companion every dog should be."--Kenneth A. Marden, President, The American Kennel Club"...Carol Lea Benjamin has written a witty, sound and thoroughly appropriate book on the extraordinary advantages that each of us who has second-hand pets knows first-hand. If you're thinking about sharing your life with a pet or with another pet, read this book first!"--John F. Kullberg, President, ASPCA

    What she did not count on was how much death would be a part of her work. Almost immediately, Chen found herself wrestling with medicine’s most profound paradox, that a profession premised on caring for the ill also systematically depersonalizes dying. Final Exam follows Chen over the course of her education, training, and practice as she grapples at strikingly close range with the problem of mortality, and struggles to reconcile the lessons of her training with her innate knowledge of shared humanity, and to separate her ideas about healing from her fierce desire to cure.From her first dissection of a cadaver in gross anatomy to the moment she first puts a scalpel to a living person; from the first time she witnesses someone flatlining in the emergency room to the first time she pronounces a patient dead, Chen is struck by her own mortal fears: there was a dying friend she could not call; a young patient’s tortured death she could not forget; even the sense of shared kinship with a corpse she could not cast aside when asked to saw its pelvis in two. Gradually, as she confronts the ways in which her fears have incapacitated her, she begins to reject what she has been taught about suppressing her feelings for her patients, and she begins to carve out a new role for herself as a physician and as human being. Chen’s transfixing and beautiful rumination on how doctors negotiate the ineluctable fact of death becomes, in the end, a brilliant questioning of how we should live.Moving and provocative, motored equally by clinical expertise and extraordinary personal grace, this is a piercing and compassionate journey into the heart of a world that is hidden and yet touches all of our lives. A superb addition to the best medical literature of our time.