Within two weeks, she and her team had designed a vaccine against a pathogen that no one had ever seen before. Less than 12 months later, vaccination was rolled out across the world to save millions of lives from Covid-19.In Vaxxers, we hear directly from Professor Gilbert and her colleague Dr Catherine Green as they reveal the inside story of making the Oxford AstraZeneca vaccine and the cutting-edge science and sheer hard work behind it. This is their story of fighting a pandemic as ordinary people in extraordinary circumstances. Sarah and Cath share the heart-stopping moments in the eye of the storm; they separate fact from fiction; they explain how they made a highly effective vaccine in record time with the eyes of the world watching; and they give us hope for the future.Vaxxers invites us into the lab to find out how science will save us from this pandemic, and how we can prepare for the inevitable next one.

    She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    I’m Tim. I’m a single cell in society’s body. U.S. society, to be specific.So let me explain why we’re here.As a writer and a generally thinky person, I’ve spent a lot of my life thinking about the society I live in, and societies in general. I’ve always imagined society as a kind of giant human—a living organism like each of us, only much bigger.When you’re a single cell in the body of a giant, it’s hard to understand what the giant’s doing, or why it is the way it is, because you can’t really zoom out and look at the whole thing all at once. But we do our best.The thing is, when I’ve recently tried to imagine what society might look like, I haven’t really been picturing this:Giant stick figure: "I am grown up."Based on what I see around me, in person and online, it seems like my society is actually more like this:Giant stick figure throwing a giant tantrum because their chocolate ice cream fell on the ground.Individual humans grow older as they age—but it kind of seems like the giant human I live in has been getting more childish each year that goes by.So I decided to write a blog post about this. But then something else happened.When I told people I was planning to write a post about society, and the way people are acting, and the way the media is acting, and the way the government is acting, and the way everyone else is acting, people kept saying the same thing to me.Don’t do it. Don’t touch it. Write about something else. Anything else. It’s just not worth it.They were right. With so many non-controversial topics to write about, why take on something so loaded and risk alienating a ton of readers? I listened to people’s warnings, and I thought about moving on to something else, but then I was like, “Wait what? I live inside a giant and the giant is having a six-year-old meltdown in the grocery store candy section and that’s a not-okay thing for me to talk about?”It hit me that what I really needed to write about was that—about why it’s perilous to write about society."

    In existence for some hundred million years, it was discovered only recently. Exploring its evolution, its daily existence, and its journey from ticks to mice to deer to humans, Karlen lucidly examines the life and world of this recently prominent germ. He also describes how it attacks the human body, and how by changing the environment, people are now much more likely to come into contact with it. Charming and thorough and smart, this book is a wonderfully written biography of your not so typical biographical subject.

    The political correctness police insist that America is “hated” around the world for being too big, too powerful, too rich, too successful, too loud, too intrusive. And besides, it’s not nice to brag. They are completely missing the point. America’s greatness, America’s exceptional greatness, is not based on that fact that we are the most powerful, most prosperous—and most generous—nation on earth. Rather, those things are the result of American Exceptionalism. To understand American Exceptionalism, as Newt Gingrich passionately argues in A Nation Like No Other, one must understand our unique birth as a nation. American Exceptionalism is found in the simple yet utterly remarkable principles expressed in the Declaration of Independence, “that all men are created equal, that we are endowed by our Creator with certain unalienable rights, that among these are life, liberty, the pursuit of happiness.” Our nation is exceptional, continues Newt, because we—unlike any nation before or since—are united by the belief and the promise that no king, no government, no ruling class has the power to infringe upon the rights of the individual. And when such a government attempts to do so, we will vigorously reject them. Sadly, many politicians and leaders today have forgotten our sacred commitment to these ideals. Our government has strayed alarmingly far from the scope of limited powers framed by our Founders. Meanwhile, the liberal media seek out, and sometimes create, stories intended to portray America as a bully and a thief. Even our own president seems clueless, assuring us that yes, yes, he believes in American exceptionalism, just like the Greeks believe in Greek exceptionalism and the British in British exceptionalism. But American Exceptionalism is not about cheerleading for the home team. It’s about recognizing and honoring the history-making, world-changing ideals our Founding Fathers enshrined to make this a nation of the people, by the people, for the people. And, as Lincoln warned, we must rededicate ourselves to those principles, lest our truly exceptional nation perish from this earth.

    Otis Brawley is the chief medical and scientific officer of The American Cancer Society, an oncologist with a dazzling clinical, research, and policy career. How We Do Harm pulls back the curtain on how medicine is really practiced in America. Brawley tells of doctors who select treatment based on payment they will receive, rather than on demonstrated scientific results; hospitals and pharmaceutical companies that seek out patients to treat even if they are not actually ill (but as long as their insurance will pay); a public primed to swallow the latest pill, no matter the cost; and rising healthcare costs for unnecessary—and often unproven—treatments that we all pay for. Brawley calls for rational healthcare, healthcare drawn from results-based, scientifically justifiable treatments, and not just the peddling of hot new drugs.Brawley's personal history – from a childhood in the gang-ridden streets of black Detroit, to the green hallways of Grady Memorial Hospital, the largest public hospital in the U.S., to the boardrooms of The American Cancer Society—results in a passionate view of medicine and the politics of illness in America - and a deep understanding of healthcare today. How We Do Harm is his well-reasoned manifesto for change.

    There they discover a city in the midst of revolution, bustling with gay men in search of liberation—few of whom are raising a child.Steve throws himself into San Francisco’s vibrant cultural scene. He takes Alysia to raucous parties, pushes her in front of the microphone at poetry readings, and introduces her to a world of artists, thinkers, and writers. But the pair live like nomads, moving from apartment to apartment, with a revolving cast of roommates and little structure. As a child Alysia views her father as a loving playmate who can transform the ordinary into magic, but as she gets older Alysia wants more than anything to fit in. The world, she learns, is hostile to difference.In Alysia’s teens, Steve’s friends—several of whom she has befriended—fall ill as AIDS starts its rampage through their community. While Alysia is studying in New York and then in France, her father tells her it’s time to come home; he’s sick with AIDS. Alysia must choose whether to take on the responsibility of caring for her father or continue the independent life she has worked so hard to create.Reconstructing their life together from a remarkable cache of her father’s journals, letters, and writings, Alysia Abbott gives us an unforgettable portrait of a tumultuous, historic time in San Francisco as well as an exquisitely moving account of a father’s legacy and a daughter’s love.It has been named a Stonewall Book Award-Israel Fishman Non-Fiction Award Honor Book for 2014.

    By his late forties, he'd gone from Princeton to Harvard Law to dramatic success as a prosecutor and attorney general to the governorship of New York. Many thought he would become the first Jewish president of the United States. Then came the prostitution scandal that shocked and mystified the nation. Peter Elkind's definitive account gets at all sides of this complex man: the well-intentioned do-gooder, the aggressive lawyer, the hardball politician, the dutiful son, the loving husband and father, and the secretive "Client 9" of the Emperor's Club escort service. Elkind interviewed dozens of key sources ranging from Spitzer's family, friends, and closest aides, to targets of his high-profile investigations, to central players in the prostitution ring. He reveals many groundbreaking new details about Spitzer's rise, his short time as governor, and the way his enemies plotted against him. The result is a gripping, almost Shakespearean narrative-a tragedy of one man's noble intentions and fatal flaws and the powerful forces (both internal and external) that destroyed him.

    In addition to offering a clear-eyed explanation of the root causes of this insidious and entrenched bias and laying out its effects, she suggests concrete steps we can take to cure it.

     Glen Retief's childhood was at once recognizably ordinary--and brutally unusual.Raised in the middle of a game preserve where his father worked, Retief's warm nuclear family was a preserve of its own, against chaotic forces just outside its borders: a childhood friend whose uncle led a death squad, while his cultured grandfather quoted Shakespeare at barbecues and abused Glen's sister in an antique-filled, tobacco-scented living room.But it was when Retief was sent to boarding school, that he was truly exposed to human cruelty and frailty. When the prefects were caught torturing younger boys, they invented "the jack bank," where underclassmen could save beatings, earn interest on their deposits, and draw on them later to atone for their supposed infractions. Retief writes movingly of the complicated emotions and politics in this punitive all-male world, and of how he navigated them, even as he began to realize that his sexuality was different than his peers'.

    A guide to women's health, including information on breast cancer, AIDS, pregnancy and childbirth, and medical practices and procedures.

    Well, I was diagnosed 24 years ago, and I still learned something new on every page.”—Michael Kinsley, Vanity Fair columnist and author of Old Age: A Beginner’s Guide Here is the book that John Vine and his wife, Joanne, wish they could have consulted when John was first diagnosed with Parkinson’s disease—a nontechnical, personal guide written from the patient’s perspective. Relying on his experiences over the past 12 years, John writes knowledgeably about all aspects of the disease. John also interviewed other Parkinson’s patients and their partners, whose stories and advice he includes throughout the book. “I wish we’d had John Vine’s book when my brother-in-law was diagnosed. The book is highly informative, unflinchingly honest, and reassuringly optimistic. It’s just what the doctor should have ordered.”—Cokie Roberts, best-selling author and political commentator on ABC News and NPR “John Vine details, in a compelling and accessible way, his experience with Parkinson’s disease. His book is an extraordinary guide to living successfully with Parkinson’s, and a must read for all who want to better understand the condition. Although diagnosed with Parkinson’s, my father lived an active and productive life until his death at age 94. As the book makes clear, while each patient’s journey is unique, common approaches are indispensable in treating the symptoms of the disease.”—Eric H. Holder, Jr. served as the 82nd Attorney General of the United States from 2009 to 2015 “John Vine has written the best primer I’ve ever read for newly diagnosed Parkinson’s patients and their families. It helps them cope with the shock of diagnosis, gives them (jargon-free) the scientific basics they need to know, describes the symptoms they may experience (making clear that every case is different) and catalogs the resources available to navigate living with Parkinson’s. John humanizes the book by describing his own experience and that of 22 other patients and their partners. I’d urge every neurologist to have copies of Vine’s primer on hand to help new PD on their journey forward.”—Morton Kondracke, author of Saving Milly: Love, Politics and Parkinson’s Disease and a member of the Founders' Council of the Michael J. Fox Foundation “My husband has PD, and I devoured this book. It’s wise, wonderfully readable, and, above all, helpful. Since John Vine has PD, he speaks with great authority about the challenges, both physical and psychological. If you have Parkinson’s, live with someone who has it, or just know someone battling the disease, A Parkinson’s Primer is for you.”—Lesley Stahl, award-winning television journalist on the CBS News program 60 Minutes “This is a remarkable book describing the personal experiences of many individuals, including the author, living with Parkinson’s disease. It captures the fact that although there are many possible symptoms in this disease, each person experiences different symptoms and copes with them in various ways. The thoughtful and insightful comments and coping strategies should be helpful for persons with PD, and their partners, regardless of the stage of the disease.”—Stephen Grill, MD, PhD, Director of the Parkinson’s & Movement Disorders Center of Maryland John M. Vine is a lawyer at Covington & Burling LLP in Washington, DC, where he is the senior member and former head of the firm’s employee benefits group. He was diagnosed with Parkinson’s in 2004.

    

    She searches the apparently fertile world around her--the emergence of thirteen-year cicadas, the birth of eaglets near her rural home, and an unusual gorilla pregnancy at a local zoo--for signs that she is not alone. Boggs also explores other aspects of fertility and infertility: the way longing for a child plays out in the classic Coen brothers film Raising Arizona; the depiction of childlessness in literature, from Macbeth to Who's Afraid of Virginia Woolf?; the financial and legal complications that accompany alternative means of family making; the private and public expressions of iconic writers grappling with motherhood and fertility. She reports, with great empathy, complex stories of couples who adopted domestically and from overseas, LGBT couples considering assisted reproduction and surrogacy, and women and men reflecting on childless or child-free lives.In The Art of Waiting, Boggs deftly distills her time of waiting into an expansive contemplation of fertility, choice, and the many possible roads to making a life and making a family.