is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    The coloring book helps you memorize the anatomy content you need to know in both veterinary medicine and veterinary technology and gives you a fun way to review the information you have studied. All illustrations in the book are suitable for coloring and are of the highest quality, created by expert medical illustrators.Organized by body region, the book is divided into sections devoted to the head and neck; neck, back, and vertebral column; thorax; abdomen; pelvis; forlimb; and hindlimb.Numbered lead lines clearly identify structures to be colored and correspond to a numbered list beneath the illustration so you can easily visualize the veterinary anatomy. Plus, you can create your own color code using the numbered boxes provided for each illustration.Comprehensive veterinary anatomy coverage helps you reinforce your understanding of canine, feline, equine, porcine, ruminants, and avian anatomy.High quality illustrations make it easy for you to color in each anatomic region and review anatomic details.Self-study format provides a fun and interactive way to prepare for exams throughout your veterinary courses.Part of Elsevier's complete veterinary anatomy learning system, integrating core anatomy knowledge, engaging review, hands-on practice, and clinical application to give you a solid foundation for success!

    The world of golf is at a crossroads. As tech­nological innovations displace traditional philosophies, the golfing community has splintered into two deeply combative factions: the old-school teachers and players who believe in feel, artistry, and imagination, and the technical minded who want to remake the game around data. In Golf’s Holy War, Brett Cyrgalis takes readers inside the heated battle playing out from weekend hackers to PGA Tour pros. At the Titleist Performance Institute in Oceanside, California, golfers clad in full-body sensors target weaknesses in their biomechanics, while others take part in mental exercises designed to test their brain’s psychological resilience. Meanwhile, coaches like Michael Hebron purge golfers of all technical infor­mation, tapping into the power of intuitive physical learning by playing rudimentary games. From historic St. Andrews to manicured Augusta, experimental com­munes in California to corporatized conferences in Orlando, William James to Ben Hogan to theoretical physics, the factions of the spiritual and technical push to redefine the boundaries of the game. And yet what does it say that Tiger Woods has orchestrated one of the greatest comebacks in sports history without the aid of a formal coach? But Golf’s Holy War is more than just a book about golf—it’s a story about modern life and how we are torn between resisting and embracing the changes brought about by the advancements of science and technology. It’s also an exploration of historical legacies, the enriching bonds of education, and the many interpretations of reality.

    This Boston-based alternative pop/German-like cabaret duo hand-designed this book which includes art, photos, commentary and 11 songs from their 2004 release. Songs included are: Bad Habit * Coin Operated Boy * Girl Anachronism * Good Day * Gravity * Half Jack * The Jeep Song * Missed Me *Perfect Fit * Slide * Truce.

    Then she is publicly hanged alongside her attacker. These events took place in 1644, in Boston, where today they would beviewed with horror. How--and when--did such a complete transformation of our culture's attitudes toward sex occur?In The Origins of Sex, Faramerz Dabhoiwala provides a landmark history, one that will revolutionize our understanding of the origins of sexuality in modern Western culture. For millennia, sex had been strictly regulated by the Church, the state, and society, who vigorously and brutally attempted topunish any sex outside of marriage. But by 1800, everything had changed. Drawing on vast research--from canon law to court cases, from novels to pornography, not to mention the diaries and letters of people great and ordinary--Dabhoiwala shows how this dramatic change came about, tracing theinterplay of intellectual trends, religious and cultural shifts, and politics and demographics. The Enlightenment led to the presumption that sex was a private matter; that morality could not be imposed; that men, not women, were the more lustful gender. Moreover, the rise of cities erodedcommunity-based moral policing, and religious divisions undermined both church authority and fear of divine punishment. Sex became a central topic in poetry, drama, and fiction; diarists such as Samuel Pepys obsessed over it. In the 1700s, it became possible for a Church of Scotland leader tocommend complete sexual liberty for both men and women. Arguing that the sexual revolution that really counted occurred long before the cultural movement of the 1960s, Dabhoiwala offers readers an engaging and wholly original look at the Western world's relationship to sex.Deeply researched and powerfully argued, The Origins of Sex is a major work of history.

    Your brain can't function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together.Sekeres, who writes regularly for the Well section of the New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family's wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimacy of the conversations Sekeres has with his patients, and watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it--describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia.The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

    The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free.Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers.Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

    These personal tragedies will, and must, be told and heard. There is, however, also a truthful and objective scientific narrative to be written about how the virus played out and how the world set about dealing with it. Spike is that story - from the inside. Its author, Jeremy Farrar, is one of the UK's leading scientists and a ­­member of the SAGE emergency committee.As head of the Wellcome Trust, and an expert in emerging infectious diseases, Jeremy Farrar was one of the first people in the world to hear about a mysterious new respiratory disease in China - and to learn that it could readily spread between people. Farrar describes how it feels as one of the key scientists at the sharp end of a fast-moving situation, when complex decisions must be made quickly amid great uncertainty. His book casts light on the UK government's claims to be 'following the science' in its response to the virus, and is informed not just by Farrar's views but by interviews with other top scientists and political figures.Farrar, who has spent his career on the frontlines of epidemics including Nipah virus in Malaysia, bird flu in Vietnam and Ebola in West Africa, also reflects on the wider issues of Covid-19: the breath-taking scientific advances in creating tests, treatments and vaccines; the challenge to world leaders to respond for the global good and the need to address inequalities that hold back success against the virus. All these shape how the world ultimately fares not just against Covid-19, but against all the major he­­alth challenges we face globally.

    It tells the astonishing story of sex in the West from the ancients to the moderns in a precise account of developments in reproductive anatomy and physiology. We cannot fail to recognize the players in Thomas Laqueur's story--the human sexual organs and pleasures, food, blood, semen, egg, sperm--but we will be amazed at the plots into which they have been woven by scientists, political activists, literary figures, and theorists of every stripe.Laqueur begins with the question of why, in the late eighteenth century, woman's orgasm came to be regarded as irrelevant to conception, and he then proceeds to retrace the dramatic changes in Western views of sexual characteristics over two millennia. Along the way, two "master plots" emerge. In the one-sex story, woman is an imperfect version of man, and her anatomy and physiology are construed accordingly: the vagina is seen as an interior penis, the womb as a scrotum, the ovaries as testicles. The body is thus a representation, not the foundation, of social gender. The second plot tends to dominate post-Enlightenment thinking while the one-sex model is firmly rooted in classical learning. The two-sex story says that the body determines gender differences, that woman is the opposite of man with incommensurably different organs, functions, and feelings. The two plots overlap; neither ever holds a monopoly. Science may establish many new facts, but even so, Laqueur argues, science was only providing a new way of speaking, a rhetoric and not a key to female liberation or to social progress. Making Sex ends with Freud, who denied the neurological evidence to insist that, as a girl becomes a woman, the locus of her sexual pleasure shifts from the clitoris to the vagina; she becomes what culture demands despite, not because of, the body. Turning Freud's famous dictum around, Laqueur posits that destiny is anatomy. Sex, in other words, is an artifice.This is a powerful story, written with verve and a keen sense of telling detail (be it technically rigorous or scabrously fanciful). Making Sex will stimulate thought, whether argument or surprised agreement, in a wide range of readers.

    And no delay causes more parental anxiety than late talking, which is associated in many parents' minds with such serious conditions as autism and severe intellectual disability. In fact, as children's speech expert Stephen Camarata points out in this enlightening book, children are late in beginning to talk for a wide variety of reasons. For some children, late talking may be a symptom of other, more serious, problems; for many others, however, it may simply be a stage with no long-term complications.Camarata describes in accessible language what science knows about the characteristics and causes of late talking. He explains that late talking is only one of a constellation of autism symptoms. Although all autistic children are late talkers, not all late-talking children are autistic.Camarata draws on more than twenty-five years of professional experience diagnosing and treating late talkers--and on his personal experience of being a late talker himself and having a late-talking son. He provides information that will help parents navigate the maze of doctors, speech therapists, early childhood services, and special education; and he describes the effect that late talking may have on children's post-talking learning styles.

    Ebola. "Killer microbes." All around us the alarms are going off, warning of the danger of new, deadly diseases. And yet, as Nancy Tomes reminds us in her absorbing book, this is really nothing new. A remarkable work of medical and cultural history, The Gospel of Germs takes us back to the first great "germ panic" in American history, which peaked in the early 1900s, to explore the origins of our modern disease consciousness.Little more than a hundred years ago, ordinary Americans had no idea that many deadly ailments were the work of microorganisms, let alone that their own behavior spread such diseases. The Gospel of Germs shows how the revolutionary findings of late nineteenth-century bacteriology made their way from the laboratory to the lavatory and kitchen, with public health reformers spreading the word and women taking up the battle on the domestic front. Drawing on a wealth of advice books, patent applications, advertisements, and oral histories, Tomes traces the new awareness of the microbe as it radiated outward from middle-class homes into the world of American business and crossed the lines of class, gender, ethnicity, and race.Just as we take some of the weapons in this germ war for granted--fixtures as familiar as the white porcelain toilet, the window screen, the refrigerator, and the vacuum cleaner--so we rarely think of the drastic measures deployed against disease in the dangerous old days before antibiotics. But, as Tomes notes, many of the hygiene rules first popularized in those days remain the foundation of infectious disease control today. Her work offers a timely look into the history of our long-standing obsession with germs, its impact on twentieth-century culture and society, and its troubling new relevance to our own lives.

    Roger Ekirch illuminates the aspects of life most often overlooked by other historians—those that unfold at night. In this "triumph of social history" (Mail on Sunday), Ekirch's "enthralling anthropology" (Harper's) exposes the nightlife that spawned a distinct culture and a refuge from daily life.Fear of crime, of fire, and of the supernatural; the importance of moonlight; the increased incidence of sickness and death at night; evening gatherings to spin wool and stories; masqued balls; inns, taverns, and brothels; the strategies of thieves, assassins, and conspirators; the protective uses of incantations, meditations, and prayers; the nature of our predecessors' sleep and dreams—Ekirch reveals all these and more in his "monumental study" (The Nation) of sociocultural history, "maintaining throughout an infectious sense of wonder" (Booklist).

    Wrigley, the great chewing-gum mogul and owner of the Chicago Cubs, who feared the effect of WWII on the major leagues, many of whose players weren't waiting to be drafted before joining up.Women answered the recruiters' call from all over the U.S. and Canada.They were drawn by the lure of bankable money and an escape from dead-end jobs and small towns.- Mary "Bonnie" Baker - the well-groomed stylish player from Regina, Saskatchewan who embodied the virtues of the All-American girl- Alma "Gabby" Ziegler - the great morale booster and captain of the Grand Rapids Chicks- Dorothy "Kammie" Kamenshek - rated the best all-round player in the League- Dorothy Schroeder - she lied about her age to join in the league's first year and played every year until the league ended 12 years laterThey were all superb athletes, but they also had to be perfect ladies.Chaperones directed their every move. Feminine uniforms included a knee-length skirt, and Charm School to teach them everything they needed to know about how to dress and act like a lady.Through all this, the All-American was a magnificent success.In its heyday, stadiums packed in fans and players were shipped off to spring training in Cuba and Florida. The All-American League teams played their first game in 1943 and their last game in 1954.

    --Hanoi to Hoboken: a round trip ticket --Living with other women --Take a lesbian to lunch --The last straw --The shape of things to come --Roxanne Dunbar --Gossip --Leadership vs. stardom --The last picture show --A manifesto for the feminist artist --Love song for feminists from Flamingo Park --I am a woman --The good fairy --It's all Dixie cups to me --The lady's not for burning.

    She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.