But it’s also messy, fallible, and about 50,000 years out of date. We cling to superstitions, remember faces but not names, miss things sitting right in front of us, and lie awake at night while our brains endlessly replay our greatest fears. Idiot Brain is for anyone who has ever wondered why their brain appears to be sabotaging their life—and what on earth it is really up to.A Library Journal Science Bestseller and a Finalist for the Goodreads Choice Award in Science Technology.

    Reeves (a biographer of Mill) and Haidt (a social psychologist) summarize Mill's three timeless arguments for free speech and the value of viewpoint diversity. They then reduce the text to half its original length, allowing Mill's best arguments and metaphors to shine. Artist Dave Cicirelli illustrates those metaphors to amplify their intuitive power. Ideal for use in college courses, or in any organization in which people would benefit from productive disagreement.

    His election night commentary became a viral sensation. A longtime progressive activist with deep roots in the conservative South, Jones has made it his mission to challenge voters and viewers to stand in one another's shoes and disagree constructively.Now, in Beyond the Messy Truth, Jones offers a blueprint for transforming our collective anxiety into meaningful change. Tough on Donald Trump but showing respect and empathy for his supporters, Jones takes aim at the failures of both parties before and after Trump's victory. He urges both sides to abandon the politics of accusation and focus on real solutions. Calling us to a deeper patriotism, he shows us how to get down to the vital business of solving, together, some of our toughest problems."The entire national conversation today can be reduced to a simple statement--'I'm right, and you're wrong, '" Jones has said. But the truth is messier; both sides have flaws. Both parties have strayed from their highest principles and let down their core constituencies. Rejecting today's political tribalism, Jones issues a stirring call for a new "bipartisanship from below." Recognizing that tough challenges require the best wisdom from both liberals and conservatives, he points us toward practical answers to problems that affect us all regardless of region or ideology: rural and inner-city poverty, unemployment, addiction, unfair incarceration, and the devastating effects of the pollution-based economy on both coal country and our urban centers.In explaining how he arrived at his views, Jones shares behind-the-scenes memories from his decades spent marching and protesting on behalf of working people, inspiring stories of ordinary citizens who became champions of their communities, and little-known examples of cooperation that have risen from the fog of partisan conflict. In his quest for positive solutions, Van Jones encourages us to set fire to our old ways of thinking about politics and come together where the pain is greatest.The audio edition includes a PDF of resources for getting involved and making a difference.Advance praise for Beyond the Messy Truth"Van Jones is a light in the darkness when we need it most. Beyond the Messy Truth breaks with the tribalism of today's politics and offers us a way forward. In the tradition of the great bridge builders of our past, Van's love for this country and all its people shines through."--Cory Booker, U.S. senator, New Jersey"In an age when hardworking families across America are feeling left behind, Van's commitment to letting other voices be heard is much needed in today's discourse."--Rick Santorum, former senator of Pennsylvania and Republican presidential candidate"Whether you agree or disagree with him, Van Jones's voice has become an integral part of our national political debate. He is one of the most provocative and interesting political figures in the country."--Bernie Sanders, U.S. senator, VermontIncludes an invaluable resource of contacts, books, media, and organizations for bipartisan bridge-building and problem solving.

    If your anxiety about global warming is dominated by fears of sea-level rise, you are barely scratching the surface of what terrors are possible. In California, wildfires now rage year-round, destroying thousands of homes. Across the US, "500-year" storms pummel communities month after month, and floods displace tens of millions annually.This is only a preview of the changes to come. And they are coming fast. Without a revolution in how billions of humans conduct their lives, parts of the Earth could become close to uninhabitable, and other parts horrifically inhospitable, as soon as the end of this century.In his travelogue of our near future, David Wallace-Wells brings into stark relief the climate troubles that await--food shortages, refugee emergencies, and other crises that will reshape the globe. But the world will be remade by warming in more profound ways as well, transforming our politics, our culture, our relationship to technology, and our sense of history. It will be all-encompassing, shaping and distorting nearly every aspect of human life as it is lived today.Like An Inconvenient Truth and Silent Spring before it, The Uninhabitable Earth is both a meditation on the devastation we have brought upon ourselves and an impassioned call to action. For just as the world was brought to the brink of catastrophe within the span of a lifetime, the responsibility to avoid it now belongs to a single generation.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    A world that is as creative and complex as it is dangerous and disturbing. A world that is much closer than you think.The dark net is an underworld that stretches from popular social media sites to the most secretive corners of the encrypted web. It is a world that frequently appears in newspaper headlines, but one that is little understood, and rarely explored. The Dark Net is a revelatory examination of the internet today, and of its most innovative and dangerous subcultures: trolls and pornographers, drug dealers and hackers, political extremists and computer scientists, Bitcoin programmers and self-harmers, libertarians and vigilantes.Based on extensive first-hand experience, exclusive interviews and shocking documentary evidence, The Dark Net offers a startling glimpse of human nature under the conditions of freedom and anonymity, and shines a light on an enigmatic and ever-changing world.

    Donald Trump’s surprise electoral victory shattered the fragile understanding between Washington and Beijing, putting the most important relationship of the twenty-first century in the hands of a novice who had bitterly attacked China from the campaign trail. Almost as soon as he entered office, Trump brought to a boil the long-simmering rivalry between the two countries, while also striking up a “friendship” with Chinese president Xi Jinping — whose manipulations of his American counterpart would undermine the White House’s already disjointed response to the historic challenge of a rising China. All the while, Trump’s own officials fought to steer U.S. policy from within. By the time the COVID-19 pandemic erupted in Wuhan, Trump’s love-hate relationship with Xi had sparked a trade war, while Xi’s aggression had pushed the world to the brink of a new Cold War. But their quarrel had also forced a long-overdue reckoning within the United States over China’s audacious foreign-influence operations, horrific human rights abuses, and creeping digital despotism. Ironically, this awakening was one of the biggest foreign-policy victories of Trump’s fractious term in office. ​Filled with shocking revelations drawn from Josh Rogin’s unparalleled access to top U.S. officials from the White House and deep within the country’s foreign policy machine, Chaos Under Heaven reveals an administration at war with itself during perhaps our most urgent hour.

    Their choices are limited by mountains, rivers, seas, and concrete. To understand world events, news organizations and other authorities often focus on people, ideas, and political movements, but without geography, we never have the full picture. Now, in the relevant and timely Prisoners of Geography, seasoned journalist Tim Marshall examines Russia, China, the USA, Latin America, the Middle East, Africa, Europe, Japan and Korea, and Greenland and the Arctic—their weather, seas, mountains, rivers, deserts, and borders—to provide a context often missing from our political reportage: how the physical characteristics of these countries affect their strengths and vulnerabilities and the decisions made by their leaders.In ten, up-to-date maps of each region, Marshall explains in clear and engaging prose the complex geo-political strategies of these key parts of the globe. What does it mean that Russia must have a navy, but also has frozen ports six months a year? How does this affect Putin’s treatment of Ukraine? How is China’s future constrained by its geography? Why will Europe never be united? Why will America never be invaded? Shining a light on the unavoidable physical realities that shape all of our aspirations and endeavors, Prisoners of Geography is the critical guide to one of the major (and most often overlooked) determining factors in world history.

    Mankind's battle to stay alive and healthy for as long as possible is our oldest, most universal struggle. With his characteristic wit and vastly informed historical scope, Roy Porter examines the war fought between disease and doctors on the battleground of the flesh from ancient times to the present. He explores the many ingenious ways in which we have attempted to overcome disease through the ages: the changing role of doctors, from ancient healers, apothecaries, and blood-letters to today's professionals; the array of drugs, from Ayurvedic remedies to the launch of Viagra; the advances in surgery, from amputations performed by barbers without anesthetic to today's sophisticated transplants; and the transformation of hospitals from Christian places of convalescence to modern medical powerhouses. Cleverly illustrated with historic line drawings, the chronic ailments of humanity provide vivid anecdotes for Porter's enlightening story of medicine's efforts to prevail over a formidable and ever-changing adversary.

    The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    That same year, a trove of Michael Jackson memorabilia—including his iconic crystal-encrusted white glove—was sold at auction for over $1 million to a guy who was, officially, just the lowly forestry minister of the tiny nation of Equatorial Guinea. And in 2014, Ukrainian revolutionaries raided the palace of their ousted president and found a zoo of peacocks, gilded toilets, and a floating restaurant modeled after a Spanish galleon. Unlikely as it might seem, there is a thread connecting these events, and Rachel Maddow follows it to its crooked source: the unimaginably lucrative and equally corrupting oil and gas industry. With her trademark black humor, Maddow takes us on a switchback journey around the globe, revealing the greed and incompetence of Big Oil and Gas along the way, and drawing a surprising conclusion about why the Russian government hacked the 2016 U.S. election. She deftly shows how Russia’s rich reserves of crude have, paradoxically, stunted its growth, forcing Putin to maintain his power by spreading Russia’s rot into its rivals, its neighbors, the West’s most important alliances, and the United States. Chevron, BP, and a host of other industry players get their star turn, most notably ExxonMobil and the deceptively well-behaved Rex Tillerson. The oil and gas industry has weakened democracies in developed and developing countries, fouled oceans and rivers, and propped up authoritarian thieves and killers. But being outraged at it is, according to Maddow, “like being indignant when a lion takes down and eats a gazelle. You can’t really blame the lion. It’s in her nature.” Blowout is a call to contain the lion: to stop subsidizing the wealthiest businesses on earth, to fight for transparency, and to check the influence of the world’s most destructive industry and its enablers. The stakes have never been higher. As Maddow writes, “Democracy either wins this one or disappears.”

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    WE ARE ANONYMOUS is the first full account of how a loosely assembled group of hackers scattered across the globe formed a new kind of insurgency, seized headlines, and tortured the feds-and the ultimate betrayal that would eventually bring them down. Parmy Olson goes behind the headlines and into the world of Anonymous and LulzSec with unprecedented access, drawing upon hundreds of conversations with the hackers themselves, including exclusive interviews with all six core members of LulzSec. In late 2010, thousands of hacktivists joined a mass digital assault on the websites of VISA, MasterCard, and PayPal to protest their treatment of WikiLeaks. Other targets were wide ranging-the websites of corporations from Sony Entertainment and Fox to the Vatican and the Church of Scientology were hacked, defaced, and embarrassed-and the message was that no one was safe. Thousands of user accounts from pornography websites were released, exposing government employees and military personnel.Although some attacks were perpetrated by masses of users who were rallied on the message boards of 4Chan, many others were masterminded by a small, tight-knit group of hackers who formed a splinter group of Anonymous called LulzSec. The legend of Anonymous and LulzSec grew in the wake of each ambitious hack. But how were they penetrating intricate corporate security systems? Were they anarchists or activists? Teams or lone wolves? A cabal of skilled hackers or a disorganized bunch of kids?WE ARE ANONYMOUS delves deep into the internet's underbelly to tell the incredible full story of the global cyber insurgency movement, and its implications for the future of computer security.

    It’s because constitutional law is so fundamental to our democracy that law schools across the country teach the subject. It's the area of law that determines what federal and state governments are permitted to do, and what rights you have as an individual citizen of the United States. In these 12 lectures, you'll get the same accessible, well-rounded introduction to constitutional law as a typical law student - but with the added benefit of noted constitutional scholar Eric Berger's brilliant insights. Taking you through all three branches of the federal government, Professor Berger uses some of the most important legal cases in the United States to probe the open-ended nature of the Constitution’s language and illustrate how legal reasoning has defined the power relationships that the Constitution governs. You’ll examine pivotal Supreme Court cases to learn how interpreting the Constitution has radically affected American society. You’ll consider the Supreme Court’s role in deciding - and sometimes avoiding - questions of constitutionality. And you’ll investigate how changes in public opinion can influence how the Supreme Court interprets the Constitution. While the open-ended nature of the Constitution’s language makes constitutional law often uncertain, these lectures offer you a better understanding of its many nuances, as well as its profound importance for the future of the United States.