The Lockheed L-188A Electra, on the way from Lima to Pucallpa, flew directly into a thunderstorm. A strike of lightning left the plane incinerated, and Juliane Diller (Koepcke), still strapped to her plane seat, fell through the night air two miles above the Earth. Her survival is unexplainable and considered a modern day miracle. Her mother was among the 91 dead and Juliane the sole survivor. For 11 days she crawled and walked alone through the jungle, fighting for her survival again with hunger and despair her only companions as maggots ate their way into her wounds.Juliane ultimately survived and went on to live an inspiring life as a scientist continually drawn back to the terrain that threatened to take her. On the 40th anniversary, she shares not only the private moments of her survival and rescue but her life in the wake of the dramatic true story.

    Humbly born on Staten Island during George Washington’s presidency, he rose from boatman to builder of the nation’s largest fleet of steamships to lord of a railroad empire. Lincoln consulted him on steamship strategy during the Civil War; Jay Gould was first his uneasy ally and then sworn enemy; and Victoria Woodhull, the first woman to run for president of the United States, was his spiritual counselor. We see Vanderbilt help to launch the transportation revolution, propel the Gold Rush, reshape Manhattan, and invent the modern corporation—in fact, as T. J. Stiles elegantly argues, Vanderbilt did more than perhaps any other individual to create the economic world we live in today.In The First Tycoon, Stiles offers the first complete, authoritative biography of this titan, and the first comprehensive account of the Commodore’s personal life. It is a sweeping, fast-moving epic, and a complex portrait of the great man. Vanderbilt, Stiles shows, embraced the philosophy of the Jacksonian Democrats and withstood attacks by his conservative enemies for being too competitive. He was a visionary who pioneered business models. He was an unschooled fistfighter who came to command the respect of New York’s social elite. And he was a father who struggled with a gambling-addicted son, a husband who was loving yet abusive, and, finally, an old man who was obsessed with contacting the dead.The First Tycoon is the exhilarating story of a man and a nation maturing together: the powerful account of a man whose life was as epic and complex as American history itself.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

    But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers--resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

    How she was treated by medical and legal officials reveals a lesser-known story of human and constitutional rights, entangled with the science of pathology and enduring questions about who Mary Mallon really was. How did her name become synonymous with deadly disease? And who is really responsible for the lasting legacy of Typhoid Mary? This thorough exploration includes an author's note, timeline, annotated source notes, and bibliography.

    In 1967, Dr. D.A. Henderson became director of a worldwide campaign to eliminate this disease from the face of the earth.This spellbinding book is Dr. Henderson’s personal story of how he led the World Health Organization’s campaign to eradicate smallpox—the only disease in history to have been deliberately eliminated. Some have called this feat "the greatest scientific and humanitarian achievement of the past century."In a lively, engrossing narrative, Dr. Henderson makes it clear that the gargantuan international effort involved more than straightforward mass vaccination. He and his staff had to cope with civil wars, floods, impassable roads, and refugees as well as formidable bureaucratic and cultural obstacles, shortages of local health personnel and meager budgets. Countries across the world joined in the effort; the United States and the Soviet Union worked together through the darkest cold war days; and professionals from more than 70 nations served as WHO field staff. On October 26, 1976, the last case of smallpox occurred. The disease that annually had killed two million people or more had been vanquished–and in just over ten years.The story did not end there. Dr. Henderson recounts in vivid detail the continuing struggle over whether to destroy the remaining virus in the two laboratories still that held it. Then came the startling discovery that the Soviet Union had been experimenting with smallpox virus as a biological weapon and producing it in large quantities. The threat of its possible use by a rogue nation or a terrorist has had to be taken seriously and Dr. Henderson has been a central figure in plans for coping with it.New methods for mass smallpox vaccination were so successful that he sought to expand the program of smallpox immunization to include polio, measles, whooping cough, diphtheria, and tetanus vaccines. That program now reaches more than four out of five children in the world and is eradicating poliomyelitis.This unique book is to be treasured—a personal and true story that proves that through cooperation and perseverance the most daunting of obstacles can be overcome.

    With a wealth of detail, "A Journal of the Plague Year" seems almost a firsthand account, taking readers through the neighborhoods, houses, and streets that have drastically changed with the rising death toll. The bustle of business and errands gives way to doors marked with the cross to signify a house of death, as well as the dead-carts transporting those struck down to the mass graves as the dead rise in number to nearly 100,000. As the epidemic progresses and the narrator encounters more stories of isolation and horror, Defoe reveals his masterful balance as both a historical and imaginative writer.

    In 1774, at the age of seventeen, Georgiana achieved immediate celebrity by marrying one of England's richest and most influential aristocrats, the Duke of Devonshire. Launched into a world of wealth and power, she quickly became the queen of fashionable society, adored by the Prince of Wales, a dear friend of Marie-Antoinette, and leader of the most important salon of her time. Not content with the role of society hostess, she used her connections to enter politics, eventually becoming more influential than most of the men who held office. Her good works and social exploits made her loved by the multitudes, but Georgiana's public success, like Diana's, concealed a personal life that was fraught with suffering. The Duke of Devonshire was unimpressed by his wife's legendary charms, preferring instead those of her closest friend, a woman with whom Georgiana herself was rumored to be on intimate terms. For over twenty years, the three lived together in a jealous and uneasy ménage à trois, during which time both women bore the Duke's children—as well as those of other men.Foreman's descriptions of Georgiana's uncontrollable gambling, all-night drinking, drug taking, and love affairs with the leading politicians of the day give us fascinating insight into the lives of the British aristocracy in the era of the madness of King George III, the American and French revolutions, and the defeat of Napoleon. A gifted young historian whom critics are already likening to Antonia Fraser, Amanda Foreman draws on a wealth of fresh research and writes colorfully and penetratingly about the fascinating Georgiana, whose struggle against her own weaknesses, whose great beauty and flamboyance, and whose determination to play a part in the affairs of the world make her a vibrant, astonishingly contemporary figure.

    Through horrible physical deformities which were almost impossible to describe, he spent much of his life exhibited as a fairground freak until even nineteenth-century sensibilities could take no more. Hounded, persecuted and starving, he ended up at London's Liverpool Street Station where he was rescued, housed and fed by the distinguished surgeon Frederick Treves. To Treves' surprise, he discovered during the course of their friendship that lurking beneath the mass of Merrick's corrupting flesh lived a spirit that was as courageous as it had been tortured, and a nature as gentle and dignified as it had been deprived and tormented. The subject of several books, a Broadway hit, and a film, Joseph Merrick has become part of popular mythology. Here, in this fully revised edition containing new details, are the true and unromantic facts of his life. This is an extraordinary and moving story, set among the brutal realities of the Victorian world, telling of a tragic individual and his survival against overwhelming odds."

    By the summer of 1918, the second wave struck as a highly contagious and lethal epidemic and within weeks exploded into a pandemic, an illness that travels rapidly from one continent to another. It would impact the course of the war, and kill many millions more soldiers than warfare itself.Of all diseases, the 1918 flu was by far the worst that has ever afflicted humankind; not even the Black Death of the Middle Ages comes close in terms of the number of lives it took. No war, no natural disaster, no famine has claimed so many. In the space of eighteen months in 1918-1919, about 500 million people--one-third of the global population at the time--came down with influenza. The exact total of lives lost will never be known, but the best estimate is between 50 and 100 million. In this powerful book, filled with black and white photographs, nonfiction master Albert Marrin examines the history, science, and impact of this great scourge--and the possibility for another worldwide pandemic today.

    Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.Deadly Outbreaks recounts the scientific adventures of a special group of intrepid individuals who investigate these outbreaks around the world and figure out how to stop them. Part homicide detective, part physician, these medical investigators must view the problem from every angle, exhausting every possible source of contamination. Any data gathered in the field must be stripped of human sorrows and carefully analyzed into hard statistics.Author Dr. Alexandra Levitt is an expert on emerging diseases and other public health threats. Here she shares insider accounts she’s collected that go behind the alarming headlines we’ve seen in the media: mysterious food poisonings, unexplained deaths at a children’s hospital, a strange neurologic disease afflicting slaughterhouse workers, flocks of birds dropping dead out of the sky, and drug-resistant malaria running rampant in a refugee camp. Meet the resourceful investigators—doctors, veterinarians, and research scientists—and discover the truth behind these cases and more.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an M.D. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.Exploring the sisters’ allies, enemies, and enduring partnership, Janice P. Nimura presents a story of trial and triumph. Together, the Blackwells founded the New York Infirmary for Indigent Women and Children, the first hospital staffed entirely by women. Both sisters were tenacious and visionary, but their convictions did not always align with the emergence of women’s rights—or with each other. From Bristol, Paris, and Edinburgh to the rising cities of antebellum America, this richly researched new biography celebrates two complicated pioneers who exploded the limits of possibility for women in medicine. As Elizabeth herself predicted, "a hundred years hence, women will not be what they are now."

    Recounts stories from her vast case files that are alternately terrifying, tragically comic, and profoundly moving, all while she deals with her best friend and fellow doctor's fight with cancer.

    It is a slave narrative of a black man who was born free in New York state but kidnapped in Washington, D.C., sold into slavery, and kept in bondage for 12 years in Louisiana. He provided details of slave markets in Washington, D.C. and New Orleans, as well as describing at length cotton and sugar cultivation on major plantations in Louisiana.