In the first anguished days, she began to create a record of her interior life as a mourner, trying to capture the paradox of grief-its monumental agony and microscopic intimacies-an endeavor that ultimately bloomed into a profound look at how caring for her mother during her illness changed and strengthened their bond. O'Rourke's story is one of a life gone off the rails, of how watching her mother's illness-and separating from her husband-left her fundamentally altered. But it is also one of resilience, as she observes her family persevere even in the face of immeasurable loss. With lyricism and unswerving candor, The Long Goodbye conveys the fleeting moments of joy that make up a life, and the way memory can lead us out of the jagged darkness of loss. Effortlessly blending research and reflection, the personal and the universal, it is not only an exceptional memoir, but a necessary one.

    Skin Game employs clear language and candid reflection to grant general readers as well as students an uncensored profile of a complex and unsettling disorder. "[This] mesmeric memoir examines the obsession with cutting that is believed to afflict somewhere around two million Americans, nearly all of them female," Francine Prose noted in Elle. "[Kettlewell's] language soars and its intensity deepens whenever she is recalling the lost joys and the thrilling sensation of sharp steel against her tender skin."

    Because if my mother is one of those crazy junk-house people, then what does that make me?When her divorced mother was diagnosed with cancer, New York City writer Jessie Sholl returned to her hometown of Minneapolis to help her prepare for her upcoming surgery and get her affairs in order. While a daunting task for any adult dealing with an aging parent, it's compounded for Sholl by one lifelong, complex, and confounding truth: her mother is a compulsive hoarder. Dirty Secret is a daughter's powerful memoir of confronting her mother's disorder, of searching for the normalcy that was never hers as a child, and, finally, cleaning out the clutter of her mother's home in the hopes of salvaging the true heart of their relationship before it's too late.Growing up, young Jessie knew her mother wasn't like other mothers: chronically disorganized, she might forgo picking Jessie up from kindergarten to spend the afternoon thrift store shopping. Now, tracing the downward spiral in her mother's hoarding behavior to the death of a long-time boyfriend, she bravely wades into a pathological sea of stuff: broken appliances, moldy cowboy boots, twenty identical pairs of graying bargain-bin sneakers, abandoned arts and crafts, newspapers, magazines, a dresser drawer crammed with discarded eyeglasses, shovelfuls of junk mail . . . the things that become a hoarder's treasures. With candor, wit, and not a drop of sentimentality, Jessie Sholl explores the many personal and psychological ramifications of hoarding while telling an unforgettable mother-daughter tale.

    The case would become one of the most famous in modern medicine—and a total failure. As Nature Made Him tells the extraordinary story of David Reimer, who, when finally informed of his medical history, made the decision to live as a male. A macabre tale of medical arrogance, it is first and foremost a human drama of one man's—and one family's—amazing survival in the face of terrible odds.

    What surfaced was terrifying: she was inhabited by 'the Troops'-92 individual personalities. This groundbreaking true story is made all the more extraordinary in that it was written by the Troops themselves. What they reveal is a spellbinding descent into a personal hell-and an ultimate deliverance for the woman they became.

    But then her son came to her with a real one…Josiah was nineteen with the world at his feet when things changed. Without warning, the new university student’s mental health deteriorated to the point that he planned his own death. His mother, bestselling author Amanda Prowse, found herself grappling for ways to help him, with no clear sense of where that could be found. This is the book they wish had been there for them during those dark times.Josiah’s situation is not unusual: the statistics on student mental health are terrifying. And he was not the only one suffering; his family was also hijacked by his illness, watching him struggle and fearing the day he might succeed in taking his life.In this book, Josiah and Amanda hope to give a voice to those who suffer, and to show them that help can be found. It is Josiah’s raw, at times bleak, sometimes humorous, but always honest account of what it is like to live with depression. It is Amanda’s heart-rending account of her pain at watching him suffer, speaking from the heart about a mother’s love for her child.For anyone with depression and anyone who loves someone with depression, Amanda and Josiah have a clear message—you are not alone, and there is hope.

    But with the unexpected death of her husband, her life became an empty, lightless space. Suddenly she was the single mother of two young boys, a widow at forty, clinging to three crumpled pages of instructions her husband had written for things like grocery shopping--things he had done while she did pioneering work as a planetary scientist at MIT. She became painfully conscious of her Asperger's, which before losing her husband had felt more like background noise. She felt, for the first time, alone in the universe.In this probing, invigoratingly honest memoir, Seager tells the story of how, as she stumblingly navigated the world of grief, she also kept looking for other worlds. She continues to develop groundbreaking projects, such as the Starshade, a sunflower-shaped instrument that, when launched into space, unfurls itself so as to block planet-obscuring starlight, and she takes solace in the alien beauty of exoplanets. At the same time, she discovers what feels every bit as wondrous: other people, reaching out across the space of her grief. Among them are the Widows of Concord, a group of women offering consolation and advice; and her beloved sons, Max and Alex. Most unexpected of all, there is another kind of one-in-a-billion match with an amateur astronomer.Equally attuned to the wonders of deep space and human connection, The Smallest Lights in the Universe is its own light in the dark.

    Ten years later, she is a psychologist running her own clinic, an award-winning writer, and happily married. The transformation in her life was brought about by Prozac. Prozac Diary is Lauren Slater's incisive account of a life restored to productivity, creativity, and love. When she wakes up one morning and finds that her demons no longer have a hold on her, Slater struggles with the strange state of being well after a lifetime of craziness. Yet this is no hymn to a miracle pharmaceutical. It is a frankly ambivalent quest for the truth of self behind an ongoing reliance on a drug. Slater also addresses Prozac's notorious "poop-out" effect and its devastating attack on her libido. This is the first memoir to reflect on long-term Prozac use, and reviewers agree that no one has written about Prozac with such beauty, honesty, and insight.

    It's caused alopecia, bulimia, and drug dependency. And Bryony is sick of it. Keeping silent about her illness has given it a cachet it simply does not deserve, so here she shares her story with trademark wit and dazzling honesty.A hugely successful columnist for the Telegraph, a bestselling author, and a happily married mother of an adorable daughter, Bryony has managed to laugh and live well while simultaneously grappling with her illness. Now it's time for her to speak out. Writing with her characteristic warmth and dark humour, Bryony explores her relationship with her OCD and depression as only she can.Mad Girl is a shocking, funny, unpredictable, heart-wrenching, raw and jaw-droppingly truthful celebration of life with mental illness.

    For as long as she could remember, she'd struggled with a series of learning disabilities that made it nearly impossible to judge time and space—standing at a cross walk, she couldn't tell you if an oncoming car would arrive in ten seconds or thirty; if you asked her to let you know when ten minutes had passed, she might notify you in a minute or an hour. These symptoms had always kept her from getting a driver's license, which she wanted to have for grad school. Instead of leaving the doctor's office with permission to drive, she left with a shocking diagnosis—doctors had found a large hole in her brain responsible for her life-long struggles. Because there aren't established tools to rely on in the wake of this unprecedented and mysterious diagnosis, Cole and her doctors and family create them, and discover firsthand how best to navigate the unique world that Cole lives in. Told without an ounce of self-pity and plenty of charm and wit, Head Case is ultimately a story of triumph, as we watch this passionate, loveable, and unsinkable young woman chart a path for herself.

    In this extraordinary memoir, she opens a window into the experience of wordlessness—the language paralysis called aphasia. In narrating the recovery of her husband, Paul West, from a stroke that reduced his vast vocabulary to a single syllable, she evokes the joy and mystery of the brain’s ability to find and connect words. Deeply rewarding to readers of all kinds, Ackerman has given us a literary love story, accessible insight into the science and medicine of brain injury,and invaluable spiritual sustenance in the face of life’s myriad physical sufferings.

    There would be uncontrolled, impulsive rages followed with denial, disavowed responsibility, and then extreme outpourings of affection. How does a child learn to feel safe in this topsy-turvy world of conditional love?Leve captures the chaos and lasting impact of a child’s life under siege and explores how the coping mechanisms she developed to survive later incapacitated her as an adult. There were material comforts, but no emotional safety, except for summer visits to her father’s home in South East Asia—an escape that was terminated after he attempted to gain custody. Following the death of a loving caretaker, a succession of replacements raised Leve—relationships which resulted in intense attachment and loss. It was not until decades later, when Leve moved to other side of the world, that she could begin to emancipate herself from the past. In a relationship with a man who has children, caring for them yields clarity of what was missing.In telling her haunting story, Leve seeks to understand the effects of chronic psychological maltreatment on a child’s developing brain, and to discover how to build a life for herself that she never dreamed possible: An unabbreviated life.

    This event, the culmination of more than twenty years of silent suffering, became the point of departure for an in-depth, groundbreaking book on depression and her struggle with the disease. The Beast shattered stereotypes and inspired countless readers to confront their own battles with mental illness. Having written that book, and having found the security of a happy marriage, Thompson assumed that she had learned to manage her illness. But when she took on one of the most emotionally demanding jobs of all—being a mother—depression returned with fresh vengeance.Very quickly Thompson realized that virtually everything she had learned up to then about dealing with depression was now either inadequate or useless. In fact, maternal depression was a different beast altogether. She tackled her problem head-on, meticulously investigating the latest scientific research and collecting the stories of nearly 400 mothers with depression. What she found was startling: a problem more widespread than she or any other mother struggling alone with this affliction could have imagined. Women make up nearly 12 million of the 19 million Americans affected by depression every year, experiencing episodes at nearly twice the rate that men do. Women suffer most frequently between the ages of twenty-five and forty-four—not coincidentally, the primary childbearing years.The Ghost in the House, the result of Thompson's extensive studies, is the first book to address maternal depression as a lifelong illness that can have profound ramifications for mother and child. A striking blend of memoir and journalism, here is an invaluable resource for the millions of women who are white-knuckling their way through what should be the most satisfying years of their lives. Thompson offers her readers a concise summary of the cutting-edge research in this field, deftly written prose, and, above all, hope.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Today he is the director of the Center for Compassion and Altruism Research and Education (CCARE) at Stanford University, of which the Dalai Lama is a founding benefactor. But back then his life was at a dead end until at twelve he wandered into a magic shop looking for a plastic thumb. Instead he met Ruth, a woman who taught him a series of exercises to ease his own suffering and manifest his greatest desires. Her final mandate was that he keep his heart open and teach these techniques to others. She gave him his first glimpse of the unique relationship between the brain and the heart.Doty would go on to put Ruth’s practices to work with extraordinary results—power and wealth that he could only imagine as a twelve-year-old, riding his orange Sting-Ray bike. But he neglects Ruth’s most important lesson, to keep his heart open, with disastrous results—until he has the opportunity to make a spectacular charitable contribution that will virtually ruin him. Part memoir, part science, part inspiration, and part practical instruction, Into the Magic Shop shows us how we can fundamentally change our lives by first changing our brains and our hearts.