He was left in a permanent vegetative state. Over the following years, Cathy and her parents took care of Matty - they built an extension onto the village pub where they lived and worked; they talked to him, fed him, bathed him, loved him. But there came a point at which it seemed the best thing they could do for Matty - and for themselves - was let him go. With unflinching honesty and raw emotional power, Cathy describes the unimaginable pain of losing her brother and the decision that changed her family's lives forever. As she delves into the past and reclaims memories that have lain buried for many years, Cathy reconnects with the bright, funny, adoring brother she lost and is finally able to see the end of his life as it really was - a last act of love. Powerful, intimate and intensely moving, this is a personal journey with universal resonance - a story of unconditional love, of grief, survival and the strength of the ties that bind. It's a story that will speak to anyone who has lost someone close to them, to anyone who has fiercely loved a sibling, and to anyone who has ever wondered whether prolonging a loved one's life might be more heartbreaking than saying goodbye.

    Kim Miller is an immaculately put-together woman with a great career, a loving boyfriend, and a beautifully tidy apartment in Brooklyn. You would never guess that she spent her childhood hiding behind the closed doors of her family’s idyllic Long Island house, navigating between teetering stacks of aging newspaper, broken computers, and boxes upon boxes of unused junk festering in every room—the product of her father’s painful and unending struggle with hoarding. In this coming-of-age story, Kim brings to life her experience of growing up in a rat-infested home, concealing her father’s shameful secret from friends for years, and of the emotional burden that ultimately led to an attempt to take her own life. And in beautiful prose, Miller sheds light on her complicated yet loving relationship with her parents that has thrived in spite of the odds. Coming Clean is a story about recognizing where we come from and the relationships that define us—and about finding peace in the homes we make for ourselves.

    Because if my mother is one of those crazy junk-house people, then what does that make me?When her divorced mother was diagnosed with cancer, New York City writer Jessie Sholl returned to her hometown of Minneapolis to help her prepare for her upcoming surgery and get her affairs in order. While a daunting task for any adult dealing with an aging parent, it's compounded for Sholl by one lifelong, complex, and confounding truth: her mother is a compulsive hoarder. Dirty Secret is a daughter's powerful memoir of confronting her mother's disorder, of searching for the normalcy that was never hers as a child, and, finally, cleaning out the clutter of her mother's home in the hopes of salvaging the true heart of their relationship before it's too late.Growing up, young Jessie knew her mother wasn't like other mothers: chronically disorganized, she might forgo picking Jessie up from kindergarten to spend the afternoon thrift store shopping. Now, tracing the downward spiral in her mother's hoarding behavior to the death of a long-time boyfriend, she bravely wades into a pathological sea of stuff: broken appliances, moldy cowboy boots, twenty identical pairs of graying bargain-bin sneakers, abandoned arts and crafts, newspapers, magazines, a dresser drawer crammed with discarded eyeglasses, shovelfuls of junk mail . . . the things that become a hoarder's treasures. With candor, wit, and not a drop of sentimentality, Jessie Sholl explores the many personal and psychological ramifications of hoarding while telling an unforgettable mother-daughter tale.

    She tried everything to appease her wakefulness: from medication to therapy, changes in her diet to changes in her living arrangements. Nothing seemed to help.The Shapeless Unease is Harvey's darkly funny and deeply intelligent anatomy of her insomnia, an immersive interior monologue of a year without one of the most basic human needs. Original and profound, and narrated with a lucid breathlessness, this is a startlingly insightful exploration of memory, writing and influence, death and the will to survive, from "this generation's Virginia Woolf" (Telegraph).

    Every passerby was an actor; every car would magically stop for him; everything he saw was a cue from "The Producer" to help inspire the performance of a lifetime. After a manic spree around Manhattan, Zack, who is bipolar, was arrested on a subway platform and admitted to Bellevue Hospital. So begins the story of Zack's freefall into psychosis and his desperate, poignant, often darkly funny struggle to claw his way back to sanity. It's a journey that will take him from New York City back to his Kansas roots and to the one person who might be able to save him, his tough, big-hearted Midwestern mother, nicknamed the Bird, whose fierce and steadfast love is the light in Zack's dark world. Before his odyssey is over, Zack will be tackled by guards in mental wards, run naked through cornfields, receive secret messages from the TV, befriend a former Navy Seal and his talking stuffed monkey, and see the Virgin Mary in the whorls of his own back hair. But with the Bird's help, he just might have a shot at pulling through, starting over, and maybe even meeting a woman who can love him back, bipolar and all. Written with raw emotional power, humor, and tenderness, GORILLA AND THE BIRD is a bravely honest account of a young man's unraveling and the relationship that saves him.

    In this compelling memoir, his first wife, Jane Hawking, relates the inside story of their extraordinary marriage. As Stephen's academic renown soared, his body was collapsing under the assaults of a motor neuron disease. Jane's candid account of trying to balance his 24-hour care with the needs of their growing family reveals the inner strength of the author, while the self-evident character and achievements of her husband make for an incredible tale presented with unflinching honesty. Jane's candor is no less apparent when the marriage finally ends in a high-profile meltdown, with Stephen leaving Jane for one of his nurses and Jane marrying an old family friend. In this exceptionally open, moving, and often funny memoir, Jane Hawking confronts not only the acutely complicated and painful dilemmas of her first marriage, but also the relationship's fault lines exposed by the pervasive effects of fame and wealth. The result is a book about optimism, love, and change that will resonate with readers everywhere.

    This cycle is at the root of all addictions, addictions to drugs, sex, love, cigarettes, soap operas, wealth, and wisdom itself. But why should this be so? Why are we desperate for what we don't have, or can't have, often at great cost to what we do have, thereby risking our peace and contentment, our safety, and even our lives?"The answer, says Dr. Marc Lewis, lies in the structure and function of the human brain. Marc Lewis is a distinguished neuroscientist. And, for many years, he was a drug addict himself, dependent on a series of dangerous substances, from LSD to heroin. His narrative moves back and forth between the often dark, compellingly recounted story of his relationship with drugs and a revelatory analysis of what was going on in his brain. He shows how drugs speak to the brain - which is designed to seek rewards and soothe pain - in its own language. He shows in detail the neural mechanics of a variety of powerful drugs and of the onset of addiction, itself a distortion of normal perception.Dr. Lewis freed himself from addiction and ended up studying it. At the age of 30 he traded in his pharmaceutical supplies for the life of a graduate student, eventually becoming a professor of developmental psychology, and then of neuroscience - his field for the last 12 years. This is the story of his journey, seen from the inside out.

    When the Close sisters were very young, their parents joined a cult called the MRA, or Moral Rearmament. The family was suddenly uprooted to a cult school in Switzerland and, ultimately, to the Belgian Congo where their father became a surgeon in the war-ravaged republic, and ultimately the personal physician to President Mobutu. Shortly after the girls returned to the US for boarding school, Jessie first started to exhibit symptoms of severe bipolar disorder (she would later learn that this ran in the family, a well-kept secret). Jessie embarked on a series of destructive marriages as the condition worsened. Glenn was always by her side throughout. Jessie's mental illness was passed on to her son, Calen. It wasn't until Calen entered McLean's psychiatric hospital that Jessie herself was diagnosed. Fifteen years and twelve years of sobriety later, Jessie is a stable and productive member of society. Glenn continues to be the major support in Jessie's life.In Resilience, the sisters share their story of triumphing over Jessie's illness. The book is written in Jessie's voice with running commentary and an epilogue written by Glenn.

    But work takes a strange turn when she is promoted onto the Pfizer account and suddenly finds herself on the other side of the curtain, developing ads for an anti-depressant drug. Overwhelmed by her professional life and the self-scrutiny it inspires, her mania takes hold. She quits her job to become an artist, only to be hospitalized by her parents against her will. Over the course of her two weeks in the ward, she tries to find a path out of the hospital and this cycle of treatment. One where she can live the life she wants, finding freedom and autonomy, without sacrificing her dreams in order to stay well.

    He was given four years to live. In 2010, in a state of lung-function collapse, Simon knew with crystal clarity that now was not his time to die. Against all prevailing medical opinion, he chose to ventilate in order to stay alive.Here, the young filmmaker, a husband and father of five small children draws us deeply into his inner world. Told in simply expressed and beautifully stark prose - in the vein of such memoirs as Jean-Dominique Bauby's The Diving Bell and the Butterfly - the result is an astonishing journey into a life which, though brutally compromised, is lived more fully and in the moment than most, revealing at its core the power of love its most potent.Written using an eye-gaze computer, It's Not Yet Dark is an unforgettable book about relationships and family, about what connects and separates us as people and, ultimately, about what it means to be alive.

    . . ranges from the shocking to the simply lovely." —Marya Hornbacher Stacy Pershall grew up depressed and too smart for her own good, a deeply strange girl in Prairie Grove, Arkansas (population 1,000), where the prevailing wisdom was that Jesus healed all. From her days as a thirteen-year-old Jesus freak, through a battle with anorexia and bulimia, her first manic episode at eighteen, and the eventual diagnosis of bipolar disorder and borderline personality disorder, this spirited and at times mordantly funny memoir chronicles Pershall's journey through hell-several breakdowns and suicide attempts—and her struggle with the mental health care system. After her 2001 suicide attempt, broadcast live on a Webcam, Pershall realized the need to heal her mind and body. She found a revolutionary cure (Dialectical Behavioral Therapy) and a new mood-stabilizing medication. She also met a tattoo artist and discovered the healing power of body modification. By giving over her skin and enduring the physical pain, she learned about the true nature of trust.

    A modern day fairy tale of New York, Your Voice in My Head is a dazzling and devastating memoir, clear-eyed and shot through with wit. In a voice unlike any other, Emma Forrest explores depression and mania, but also the beauty of love—and the heartbreak of loss.

    In 1887, 23-year-old reporter Nellie Bly had herself committed to a New York City asylum for 10 days to expose the horrific conditions for 19th-century century mental patients.

    In this extraordinary memoir, she opens a window into the experience of wordlessness—the language paralysis called aphasia. In narrating the recovery of her husband, Paul West, from a stroke that reduced his vast vocabulary to a single syllable, she evokes the joy and mystery of the brain’s ability to find and connect words. Deeply rewarding to readers of all kinds, Ackerman has given us a literary love story, accessible insight into the science and medicine of brain injury,and invaluable spiritual sustenance in the face of life’s myriad physical sufferings.

    Ten years later, she is a psychologist running her own clinic, an award-winning writer, and happily married. The transformation in her life was brought about by Prozac. Prozac Diary is Lauren Slater's incisive account of a life restored to productivity, creativity, and love. When she wakes up one morning and finds that her demons no longer have a hold on her, Slater struggles with the strange state of being well after a lifetime of craziness. Yet this is no hymn to a miracle pharmaceutical. It is a frankly ambivalent quest for the truth of self behind an ongoing reliance on a drug. Slater also addresses Prozac's notorious "poop-out" effect and its devastating attack on her libido. This is the first memoir to reflect on long-term Prozac use, and reviewers agree that no one has written about Prozac with such beauty, honesty, and insight.