Although her body healed rapidly, her memories never returned. Yet after just three weeks in the hospital, Su was released and once again charged with the care of two toddlers and a busy household. Adrift in a world about which she understood almost nothing, Su became an adept mimic, gradually creating routines and rituals that sheltered her and her family, however narrowly, from the near-daily threat of disaster, or so she thought. Though Su would eventually relearn to tie her shoes, cook a meal, and read and write, nearly twenty years would pass before a series of personally devastating events shattered the normal life she had worked so hard to build, and she realized that she would have to grow up all over again.In her own indelible voice, Su offers us a view from the inside of a terrible injury, with the hope that her story will help give other brain injury sufferers and their families the resolve and courage to build their lives anew. Piercing, heartbreaking, but finally uplifting, this book is the true story of a woman determined to live life on her own terms.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Leana Wen likes to use. You don’t know it because good public health is invisible. It becomes visible only in its absence, when it is underfunded and ignored, a bitter truth laid bare as never before by the devastation of COVID-19.Leana Wen—emergency physician, former Baltimore health commissioner, CNN medical analyst, and Washington Post contributing columnist—has lived on the front lines of public health, leading the fight against the opioid epidemic, outbreaks of infectious disease, maternal and infant mortality, and COVID-19 disinformation. Here, in gripping detail, Wen lays bare the lifesaving work of public health and its innovative approach to social ills, treating gun violence as a contagious disease, for example, and racism as a threat to health.Wen also tells her own uniquely American story: an immigrant from China, she and her family received food stamps and were at times homeless despite her parents working multiple jobs. That child went on to attend college at thirteen, become a Rhodes scholar, and turn to public health as the way to make a difference in the country that had offered her such possibilities.Ultimately, she insists, it is public health that ensures citizens are not robbed of decades of life, and that where children live does not determine whether they live.

    This "rueful, riveting, piercingly funny" (Julia Cameron) book is written by a Harvard graduate--but it tells a story in which hearts trump brains every time. It's a tale about mothering a Down syndrome child that opts for sass over sap, and it's a book of heavenly visions and inexplicable phenomena that's as down-to-earth as anyone could ask for. This small masterpiece is Martha Beck's own story--of leaving behind the life of a stressed-out superachiever, opening herself to things she'd never dared consider, meeting her son for (maybe) the first time...and "unlearn[ing] virtually everything Harvard taught [her] about what is precious and what is garbage.""Beck [is] very funny, particularly about the most serious possible subjects--childbirth, angels and surviving at Harvard." --New York Times Book Review"Immensely appealing...hooked me on the first page and propelled me right through visions and out-of-body experiences I would normally scoff at." --Detroit Free Press"I challenge any reader not to be moved by it." --Newsday"Brilliant." --Minneapolis Star-Tribune

    A member of the Dalhousie University track and field team, he was about to start classes at Dalhousie's medical school. He had attended a medical school in the Caribbean; he worked at a group home for adults with disabilities. "There's times for whatever reason that things don't go quite as planned," a Halifax police officer told Sandeson shortly after he was arrested for the first-degree murder of Taylor Samson, who also, on the surface, seemed like a model son. Samson lived in a fraternity house near Dalhousie, and when the six-foot-five physics student disappeared without a trace, the focus eventually turned to Sandeson.Sandeson's trial, with surprising testimony and the unanswered question of what happened to Samson's body, gripped the university city for months. Through interviews with friends and relatives, as well as transcripts of the trial and Sandeson's police interrogation, award-winning journalist Kayla Hounsell paints a complex portrait of both the victim and killer, two young men who seemed destined for bright futures. First Degree includes previously unpublished photos and details never made public until now.

    The deafening thrum of the helicopter announces the unknown perils and potential havoc that await. A critical care and emergency flight nurse, Culkin treats patients who are most often in mortal danger. Aboard the Agusta, she is entrusted with the life of a seventeen-year-old pulled from the wreckage of a headon collision as his father calls out a wrenching plea from below; she cares for a middle-aged man who is bleeding to death internally, remembering the four daughters who have kissed him goodbye, possibly for the last time. It is the arduous and acute struggle to keep her patients alive en route to the hospital that is Jennifer Culkin's most profound duty.Culkin is no stranger to death and its dramas, or the urgency that accompanies them. Her memoir pulls us into the neonatal intensive care unit, where she labors to ventilate an eleven-ounce preemie, the smallest human she has ever cared for. The tenuous lines between life and death lead us to the pediatric intensive care unit, where she looks after children seemingly too small to contain their devastating illnesses.As her personal life begins to mirror the intensity of her work, Culkin writes poignantly of attending her dying mother, who refuses to decide whether to prolong her life. She recounts with tenderness and exasperation the experience of looking after her widowed father, who faces death with dramatic stubbornness, ignoring medical advice and rejecting even basic treatment. Tempering her profound insights with humor, Culkin relates her taste for the edge, her own risky gambles, and her ongoing battle with multiple sclerosis. Finally, Culkin takes us back to flying, with the dramatic and redemptive stories of her colleagues who have perished in helicopter crashes in their very exceptional line of duty.A Final Arc of Sky does more than plunge readers into the chaos of emergency medicine; it is also a masterful reflection on the pivotal moments of our lives, on the beautiful fragility of our mortality.

    Blending months of classroom instruction with ER rotations and a grueling field internship with the Los Angeles Fire Department, UCLA’s paramedic program is like a mix of boot camp and med school. It would turn out to be the hardest thing Grange had ever done—but also the most transformational and inspiring.An in-depth look at the trials and tragedies that paramedic students experience daily, Lights and Sirens is ultimately about the best part of humanity—people working together to help save a human life.

    This singular memoir--a classic American story--invites readers to Erin's corner of her beloved Maine to share the real person behind the "girl from Freedom" fairytale, and the not-so-picture-perfect struggles that have taken every ounce of her strength to overcome, and that make Erin's life triumphant.In Finding Freedom, Erin opens up to the challenges, stumbles, and victories that have led her to the exact place she was ever meant to be, telling stories of multiple rock-bottoms, of darkness and anxiety, of survival as a jobless single mother, of pills that promised release but delivered addiction, of a man who seemed to offer salvation but in the end ripped away her very sense of self. And of the beautiful son who was her guiding light as she slowly rebuilt her personal and culinary life around the solace she found in food--as a source of comfort, a sense of place, as a way of bringing goodness into the world. Erin's experiences with deep loss and abiding hope, told with both honesty and humor, will resonate with women everywhere who are determined to find their voices, create community, grow stronger and discover their best-selves despite seemingly impossible odds. Set against the backdrop of rural Maine and its lushly intense, bountiful seasons, Erin reveals the passion and courage needed to invent oneself anew, and the poignant, timeless connections between food and generosity, renewal and freedom.

    She ruled China for decades and brought a medieval empire into the modern age. At the age of sixteen, in a nationwide selection for royal consorts, Cixi was chosen as one of the emperor’s numerous concubines. When he died in 1861, their five-year-old son succeeded to the throne. Cixi at once launched a palace coup against the regents appointed by her husband and made herself the real ruler of China—behind the throne, literally, with a silk screen separating her from her officials who were all male.In this groundbreaking biography, Jung Chang vividly describes how Cixi fought against monumental obstacles to change China. Under her the ancient country attained virtually all the attributes of a modern state: industries, railways, electricity, the telegraph and an army and navy with up-to-date weaponry. It was she who abolished gruesome punishments like “death by a thousand cuts” and put an end to foot-binding. She inaugurated women’s liberation and embarked on the path to introduce parliamentary elections to China. Chang comprehensively overturns the conventional view of Cixi as a diehard conservative and cruel despot.Cixi reigned during extraordinary times and had to deal with a host of major national crises: the Taiping and Boxer rebellions, wars with France and Japan—and an invasion by eight allied powers including Britain, Germany, Russia and the United States. Jung Chang not only records the Empress Dowager’s conduct of domestic and foreign affairs, but also takes the reader into the depths of her splendid Summer Palace and the harem of Beijing’s Forbidden City, where she lived surrounded by eunuchs—one of whom she fell in love, with tragic consequences. The world Chang describes here, in fascinating detail, seems almost unbelievable in its extraordinary mixture of the very old and the very new.Based on newly available, mostly Chinese, historical documents such as court records, official and private correspondence, diaries and eyewitness accounts, this biography will revolutionize historical thinking about a crucial period in China’s—and the world’s—history. Packed with drama, fast paced and gripping, it is both a panoramic depiction of the birth of modern China and an intimate portrait of a woman: as the concubine to a monarch, as the absolute ruler of a third of the world’s population, and as a unique stateswoman.

     It is a remarkable portrait, too, of the life of a psychiatric asylum--the sort of community in which, for better and for worse, hundreds of thousands of people lived out their lives.More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

    At the time of my arrest, I was a thirty-seven year old Harvard graduate with medical and post-doctoral degrees. I attended one of the finest residency and fellowship training programs in the world at the University of California, San Francisco. I played two sports in college, earned awards at every level of education and training, had wonderful friends and a beautiful three-year-old daughter. Having grown up the son of a restaurant manager and a housewife, I had transcended the humble beginnings of a small Midwestern town to become the quintessential American Dream.Or so I thought. But with my arrest on felony importation charges, everything I had worked so hard for was swept away and the entire trajectory of my life was indelibly altered. I would embark on a three year battle not only for my medical license, but also for my freedom. This journey would lead to intense personal introspection, and in that process, I would discover with ugliness, there was also beauty, and with punishment, mercy.There are many reasons I have written this manuscript, with one of the most important being that I hoped my story would resonate with others who have gone through difficult circumstances as a consequence of a dark side of their personality. With this book, I hope to inspire others to accept and embrace the good and bad, while continually striving for improved self-understanding and acceptance.I have changed names primarily for legal purposes, but the facts are unchanged. Although the events described in the book occurred more than ten years ago, I think about them nearly every day. The shame and humiliation are ever-present. Any simple Google search of my name reveals the truth, and that truth has affected me over and over, despite the years, as it probably should. As the judge told me that day in a federal courtroom, "You have betrayed the public's trust." This is my confessional.

    And yet she is often confounded by the cases she describes in her column: unexpected collections of symptoms that she and other physicians struggle to diagnose.A twenty-eight-year-old man, vacationing in the Bahamas for his birthday, tries some barracuda for dinner. Hours later, he collapses on the dance floor with crippling stomach pains. A middle-aged woman returns to her doctor, after visiting two days earlier with a mild rash on the back of her hands. Now the rash has turned purple and has spread across her entire body in whiplike streaks. A young elephant trainer in a traveling circus, once head-butted by a rogue zebra, is suddenly beset with splitting headaches, as if someone were "slamming a door inside his head."In each of these cases, the path to diagnosis--and treatment--is winding, sometimes frustratingly unclear. Dr. Sanders shows how making the right diagnosis requires expertise, painstaking procedure, and sometimes a little luck. Intricate, gripping, and full of twists and turns, Diagnosis puts readers in the doctor's place. It lets them see what doctors see, feel the uncertainty they feel--and experience the thrill when the puzzle is finally solved.

    A deeply moving and emotional read, STRUNG OUT challenges our preconceived ideas of what addiction looks like.”—Stephanie Land, New York Times bestselling author of MaidIn this deeply personal and illuminating memoir about her fifteen-year struggle with heroin, Khar sheds profound light on the opioid crisis and gives a voice to the over two million people in America currently battling with this addiction.Growing up in LA, Erin Khar hid behind a picture-perfect childhood filled with excellent grades, a popular group of friends and horseback riding. After first experimenting with her grandmother’s expired painkillers, Khar started using heroin when she was thirteen. The drug allowed her to escape from pressures to be perfect and suppress all the heavy feelings she couldn’t understand.This fiercely honest memoir explores how heroin shaped every aspect of her life for the next fifteen years and details the various lies she told herself, and others, about her drug use. With enormous heart and wisdom, she shows how the shame and stigma surrounding addiction, which fuels denial and deceit, is so often what keeps addicts from getting help. There is no one path to recovery, and for Khar, it was in motherhood that she found the inner strength and self-forgiveness to quit heroin and fight for her life.Strung Out is a life-affirming story of resilience while also a gripping investigation into the psychology of addiction and why people turn to opioids in the first place.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Some of them, he’s the first to admit, seem unbelievable--like chasing a naked patient around the ER parking lot in the middle of the night . . . or constructing a horse sling for a 700-pound patient . . . or treating a patient who swallowed a cigarette lighter . . . or serving as a major in the U.S. Army Medical Corps during the Cold War, on orders of the president and with a KGB agent hot on his tail in the Soviet Union. In his wildest dreams, Dr. Waymack could never have imagined most of what he experienced as a doctor, but these stories are all true. He couldn’t have made them up if he tried.