But with the unexpected death of her husband, her life became an empty, lightless space. Suddenly she was the single mother of two young boys, a widow at forty, clinging to three crumpled pages of instructions her husband had written for things like grocery shopping--things he had done while she did pioneering work as a planetary scientist at MIT. She became painfully conscious of her Asperger's, which before losing her husband had felt more like background noise. She felt, for the first time, alone in the universe.In this probing, invigoratingly honest memoir, Seager tells the story of how, as she stumblingly navigated the world of grief, she also kept looking for other worlds. She continues to develop groundbreaking projects, such as the Starshade, a sunflower-shaped instrument that, when launched into space, unfurls itself so as to block planet-obscuring starlight, and she takes solace in the alien beauty of exoplanets. At the same time, she discovers what feels every bit as wondrous: other people, reaching out across the space of her grief. Among them are the Widows of Concord, a group of women offering consolation and advice; and her beloved sons, Max and Alex. Most unexpected of all, there is another kind of one-in-a-billion match with an amateur astronomer.Equally attuned to the wonders of deep space and human connection, The Smallest Lights in the Universe is its own light in the dark.

    This unexpected journey lit a fire in me that would carry me through the next 23 years of nursing.I’ve witnessed births, deaths and all that lies in between. I’ve been exhausted, heartbroken and sexually assaulted. I’ve anguished over children who aren’t my own and I have battled an illness that forced me to change places from nurse to patient.But I have also had a blast. I’ve met and learned from extraordinary characters who I can never forget. I’d love you to meet them too and share the crazy, sad, shocking, moving and hilarious experiences that made me Blue Girl.

    She tried everything to appease her wakefulness: from medication to therapy, changes in her diet to changes in her living arrangements. Nothing seemed to help.The Shapeless Unease is Harvey's darkly funny and deeply intelligent anatomy of her insomnia, an immersive interior monologue of a year without one of the most basic human needs. Original and profound, and narrated with a lucid breathlessness, this is a startlingly insightful exploration of memory, writing and influence, death and the will to survive, from "this generation's Virginia Woolf" (Telegraph).

    He was at the center of the wildest play in college football history, simply known as "The Play." Before he signed a pro contract, there was "The Trade." His NFL career included "The Drive" and "The Fumble," and, of course, "The Helicopter," one of the most iconic highlights in Super Bowl lore. There are so many memorable comeback victories and heroic plays that people have to make lists rather than consider Elway in the context of any singular event.Yet Elway's story is filled with one challenge after another. At Stanford, he never played in a Bowl game. He was ripped for being petulant after refusing to sign with the Baltimore Colts when he was drafted No. 1 overall, and later for his failure to get along with coach Dan Reeves. Over the first 10 years of his career, Elway led Denver to three Super Bowls, but lost in progressively worse fashion each time. Finally, after fifteen years of perseverance, Elway led the Broncos to back-to-back championships, including the biggest upset in Super Bowl history. Elway won the MVP award in his final Super Bowl and then walked away from the game.Within four years, Elway's father and twin sister both died, and he went through a difficult divorce. Reeling in his post-retirement, he returned to football . . . at the bottom, running the Colorado Crush of the Arena Football League. He waited more than a decade to return to his beloved Broncos. While many people doubted him initially, Elway navigated the Broncos through massive changes and to victory in Super Bowl 50, making Elway the rare Hall of Famer to win a title both on and off the field. Elway has put his passion for competition on display in a way that only a handful of other NFL greats have ever done, and Elway is the most complete look at one of the most accomplished legends in the history of American sports.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    Debbie St. Germain’s death in her remote trailer, apparently at the hands of her fifth husband, is a passing curiosity. “A real-life old West murder mystery,” the local TV announcers intone before the commercial break, while barroom gossips snicker cruelly. But for her twenty-year-old son, Justin St. Germain, the tragedy marks the line that separates his world into before and after.   Long after his mother’s death is “solved,” closure still seems missing. Distancing himself from the legendary town of his childhood, Justin makes another life a world away in San Francisco and achieves all the surface successes that would have filled his mother with pride. Yet years later he’s still sleeping with a loaded rifle under his bed. Ultimately, he is pulled back to the desert landscape of his childhood on a search to make sense of the unfathomable. What made his mother, a onetime army paratrooper, the type of woman who would stand up to any man except the men she was in love with? What led her to move from place to place, house to house, man to man, job to job, until finally she found herself in a desperate and deteriorating situation, living on an isolated patch of desert with an unstable ex-cop?   Justin’s journey takes him back to the ghost town of Wyatt Earp and the Gunfight at the O.K. Corral, to the trailers he and Debbie shared, to the string of stepfathers who were a constant, sometimes threatening presence in his life, to a harsh world on the margins full of men and women all struggling to define what family means. He decides to confront people from his past and delve into the police records in an attempt to make sense of his mother’s life and death. All the while he tries to be the type of man she would have wanted him to be.   Brutally honest and beautifully written, Son of a Gun is a brave, unexpected and unforgettable memoir.

    Styron is perhaps the first writer to convey the full terror of depression's psychic landscape, as well as the illuminating path to recovery.

    because he wants to watch Caillou, he’s an a-hole. When your daughter outlines every corner of your living room with a purple crayon, she’s an a-hole. When your rug rats purposely decorate the kitchen ceiling with their smoothies, they’re a-holes. So it’s only natural to want to kill them sometimes. Of course you can’t because you’d go to prison, and then you’d really never get to poop alone again. Plus, there’s that whole loving them more than anything in the whole world thing. Karen Alpert is the writer of the popular blog Baby Sideburns. You may have seen some of her more viral posts like “Ten Things I Really F’ing Want for Mother’s Day,” “Daddy Sticker Chart” and “What NOT to F’ing Buy My Kids this Holiday.” Or you may know her from her Facebook page that has over 130,000 followers. I Heart My Little A-Holes is full of hilarious stories, lists, thoughts and pictures that will make you laugh so hard you’ll wish you were wearing a diaper.

    There’s also Felicia Day—violinist, filmmaker, Internet entrepreneur, compulsive gamer, hoagie specialist, and former lonely homeschooled girl who overcame her isolated childhood to become the ruler of a new world... or at least semi-influential in the world of Internet Geeks and Goodreads book clubs.After growing up in the south where she was "home-schooled for hippie reasons", Felicia moved to Hollywood to pursue her dream of becoming an actress and was immediately typecast as a crazy cat-lady secretary. But Felicia’s misadventures in Hollywood led her to produce her own web series, own her own production company, and become an Internet star.Felicia’s short-ish life and her rags-to-riches rise to Internet fame launched her career as one of the most influential creators in new media. Now, Felicia’s strange world is filled with thoughts on creativity, video games, and a dash of mild feminist activism—just like her memoir.Hilarious and inspirational, You’re Never Weird on the Internet (Almost) is proof that everyone should embrace what makes them different and be brave enough to share it with the world, because anything is possible now—even for a digital misfit.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    When they began living together, she was 25; he was 58. Three years later, they married, but within a year and a half, she left him, amidst reports of loud arguments and spanking episodes. Their divorce, finalized in 1968, was a major news splash even in that pre-TMZ, pre-internet era. Grant died in 1986, but Cannon has continued to wrestle with the details, the rights, and the wrongs of their relationship. Dear Cary is a memoir that celebrates and scrutinizes the great love of her life.

    Enter Ting, a seven-pound Korat who changed his life, and the life of the family. All kittens are mischievous, but Ting “the cat grenade” was real trouble. She was also smart, endearing, and the soul of the Warren family.     In late 2008, Lissa’s father died of a heart attack. The images from that night still haunt her—especially the EKG readout ending in one long, devastating em dash. Less than a year later, Lissa and her mother stared at another EKG readout, this time for Ting. A living feline extension of the man they missed so much—the man they had tried, but failed, to save—she was diagnosed with a potentially fatal heart condition. The only option was to have a human pacemaker implanted in the cat—a procedure even the best animal hospital in Boston hadn’t performed in a decade. Determined not to lose another family member, they embarked on a medical odyssey on behalf of the gray cat who had been her father’s shadow—a journey that would prepare one of them for her own serious diagnosis.   A gorgeously written memoir about grief, hope, and how pets both complicate and enrich our lives, The Good Luck Cat is a testament to the power of the human—and the feline—spirit.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Today, it is the most common form of officially classified mental illness. Scott Stossel gracefully guides us across the terrain of an affliction that is pervasive yet too often misunderstood. Drawing on his own long-standing battle with anxiety, Stossel presents an astonishing history, at once intimate and authoritative, of the efforts to understand the condition from medical, cultural, philosophical, and experiential perspectives. He ranges from the earliest medical reports of Galen and Hippocrates, through later observations by Robert Burton and Søren Kierkegaard, to the investigations by great nineteenth-century scientists, such as Charles Darwin, William James, and Sigmund Freud, as they began to explore its sources and causes, to the latest research by neuroscientists and geneticists. Stossel reports on famous individuals who struggled with anxiety, as well as on the afflicted generations of his own family. His portrait of anxiety reveals not only the emotion’s myriad manifestations and the anguish anxiety produces but also the countless psychotherapies, medications, and other (often outlandish) treatments that have been developed to counteract it. Stossel vividly depicts anxiety’s human toll—its crippling impact, its devastating power to paralyze—while at the same time exploring how those who suffer from it find ways to manage and control it. My Age of Anxiety is learned and empathetic, humorous and inspirational, offering the reader great insight into the biological, cultural, and environmental factors that contribute to the affliction.

    In Also Human, vocational psychologist Caroline Elton introduces us to some of the distressed physicians who have come to her for help: doctors who face psychological challenges that threaten to destroy their careers and lives, including an obstetrician grappling with his own homosexuality, a high-achieving junior doctor who walks out of her first job within weeks of starting, and an oncology resident who faints when confronted with cancer patients. Entering a doctor's office can be terrifying, sometimes for the doctor most of all. By examining the inner lives of these professionals, Also Human offers readers insight into, and empathy for, the very real struggles of those who hold power over life and death.