The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir


Steffanie Strathdee - 2019
    What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

The Revenge Of Geography: What the Map Tells Us About Coming Conflicts and the Battle Against Fate


Robert D. Kaplan - 2012
    Kaplan, the bestselling author of Monsoon and Balkan Ghosts, offers a revelatory new prism through which to view global upheavals and to understand what lies ahead for continents and countries around the world.   In The Revenge of Geography, Kaplan builds on the insights, discoveries, and theories of great geographers and geopolitical thinkers of the near and distant past to look back at critical pivots in history and then to look forward at the evolving global scene. Kaplan traces the history of the world’s hot spots by examining their climates, topographies, and proximities to other embattled lands. The Russian steppe’s pitiless climate and limited vegetation bred hard and cruel men bent on destruction, for example, while Nazi geopoliticians distorted geopolitics entirely, calculating that space on the globe used by the British Empire and the Soviet Union could be swallowed by a greater German homeland.   Kaplan then applies the lessons learned to the present crises in Europe, Russia, China, the Indian subcontinent, Turkey, Iran, and the Arab Middle East. The result is a holistic interpretation of the next cycle of conflict throughout Eurasia. Remarkably, the future can be understood in the context of temperature, land allotment, and other physical certainties: China, able to feed only 23 percent of its people from land that is only 7 percent arable, has sought energy, minerals, and metals from such brutal regimes as Burma, Iran, and Zimbabwe, putting it in moral conflict with the United States. Afghanistan’s porous borders will keep it the principal invasion route into India, and a vital rear base for Pakistan, India’s main enemy. Iran will exploit the advantage of being the only country that straddles both energy-producing areas of the Persian Gulf and the Caspian Sea. Finally, Kaplan posits that the United States might rue engaging in far-flung conflicts with Iraq and Afghanistan rather than tending to its direct neighbor Mexico, which is on the verge of becoming a semifailed state due to drug cartel carnage.   A brilliant rebuttal to thinkers who suggest that globalism will trump geography, this indispensable work shows how timeless truths and natural facts can help prevent this century’s looming cataclysms.

All That Remains: A Life in Death


Sue Black - 2018
    As Professor of Anatomy and Forensic Anthropology, she focuses on mortal remains in her lab, at burial sites, at scenes of violence, murder and criminal dismemberment, and when investigating mass fatalities due to war, accident or natural disaster. In All that Remains she reveals the many faces of death she has come to know, using key cases to explore how forensic science has developed, and what her work has taught her. Do we expect a book about death to be sad? Macabre? Sue’s book is neither. There is tragedy, but there is also humour in stories as gripping as the best crime novel. Our own death will remain a great unknown. But as an expert witness from the final frontier, Sue Black is the wisest, most reassuring, most compelling of guides.

The Fever of 1721: The Epidemic That Revolutionized Medicine and American Politics


Stephen Coss - 2016
    This is the story of a fateful year that prefigured the events of 1776.In The Fever of 1721, Stephen Coss brings to life an amazing cast of characters in a year that changed the course of medical history, American journalism, and colonial revolution, including Cotton Mather, the great Puritan preacher, son of the president of Harvard College; Zabdiel Boylston, a doctor whose name is on one of Boston's grand avenues; James and his younger brother Benjamin Franklin; and Elisha Cooke and his protegee; Samuel Adams.During the worst smallpox epidemic in Boston history Mather convinced Doctor Boylston to try a procedure that he believed would prevent death--by making an incision in the arm of a healthy person and implanting it with smallpox. Inoculation led to vaccination, one of the most profound medical discoveries in history. Public outrage forced Boylston into hiding, and Mather's house was firebombed.A political fever also raged. Elisha Cooke was challenging the Crown for control of the colony and finally forced Royal Governor Samuel Shute to flee Massachusetts. Samuel Adams and the Patriots would build on this to resist the British in the run-up to the American Revolution. And a bold young printer James Franklin (who was on the wrong side of the controversy on inoculation), launched America's first independent newspaper and landed in jail. His teenage brother and apprentice, Benjamin Franklin, however, learned his trade in James' shop and became a father of the Independence movement.One by one, the atmosphere in Boston in 1721 simmered and ultimately boiled over, leading to the full drama of the American Revolution.

Chasing the Scream: The First and Last Days of the War on Drugs


Johann Hari - 2015
    On the eve of this centenary, journalist Johann Hari set off on an epic three-year, thirty-thousand-mile journey into the war on drugs. What he found is that more and more people all over the world have begun to recognize three startling truths: Drugs are not what we think they are. Addiction is not what we think it is. And the drug war has very different motives to the ones we have seen on our TV screens for so long.In Chasing the Scream, Hari reveals his discoveries entirely through the stories of people across the world whose lives have been transformed by this war. They range from a transsexual crack dealer in Brooklyn searching for her mother, to a teenage hit-man in Mexico searching for a way out. It begins with Hari's discovery that at the birth of the drug war, Billie Holiday was stalked and killed by the man who launched this crusade--and it ends with the story of a brave doctor who has led his country to decriminalize every drug, from cannabis to crack, with remarkable results.Chasing the Scream lays bare what we really have been chasing in our century of drug war--in our hunger for drugs, and in our attempt to destroy them. This book will challenge and change how you think about one of the most controversial--and consequential--questions of our time.

The Basque History of the World: The Story of a Nation


Mark Kurlansky - 1999
    No one has ever been able to determine their origins, and even the Basques' language, Euskera—the most ancient in Europe—is related to none other on earth. For centuries, their influence has been felt in nearly every realm, from religion to sports to commerce. Even today, the Basques are enjoying what may be the most important cultural renaissance in their long existence.Mark Kurlansky's passion for the Basque people and his exuberant eye for detail shine throughout this fascinating book. Like Cod, The Basque History of the World,blends human stories with economic, political, literary, and culinary history into a rich and heroic tale.Among the Basques' greatest accomplishments:Exploration—the first man to circumnavigate the globe, Juan Sebastian de Elcano, was a Basque and the Basques were the second Europeans, after the Vikings, in North America Gastronomy and agriculture—they were the first Europeans to eat corn and chili peppers and cultivate tobacco, and were among the first to use chocolate Religion—Ignatius Loyola, a Basque, founded the Jesuit religious order Business and politics—they introduced capitalism and modern commercial banking to southern Europe Recreation—they invented beach resorts, jai alai, and racing regattas, and were the first Europeans to play sports with balls“A delectable portrait of an uncanny, indomitable nation.” –Newsday“Exciting, Illuminating, and thought provoking.” –The Boston Globe"Entertaining and instructive… [Kurlansky’s] approach is unorthodox, mixing history with anecdotes, poems with recipes.” –The New York Times Book Review

How Democracies Die: What History Reveals About Our Future


Steven Levitsky - 2018
    Democracy no longer ends with a bang--in a revolution or military coup--but with a whimper: the slow, steady weakening of critical institutions, such as the judiciary and the press, and the gradual erosion of long-standing political norms. The good news is that there are several exit ramps on the road to authoritarianism. The bad news is that, by electing Trump, we have already passed the first one.Drawing on decades of research and a wide range of historical and global examples, from 1930s Europe to contemporary Hungary, Turkey, and Venezuela, to the American South during Jim Crow, Levitsky and Ziblatt show how democracies die--and how ours can be saved.

Origins: How Earth's History Shaped Human History


Lewis Dartnell - 2019
    But how has the earth itself determined our destiny? Our planet wobbles, driving changes in climate that forced the transition from nomadism to farming. Mountainous terrain led to the development of democracy in Greece. Atmospheric circulation patterns later on shaped the progression of global exploration, colonization, and trade. Even today, voting behavior in the south-east United States ultimately follows the underlying pattern of 75 million-year-old sediments from an ancient sea. Everywhere is the deep imprint of the planetary on the human.From the cultivation of the first crops to the founding of modern states, Origins reveals the breathtaking impact of the earth beneath our feet on the shape of our human civilizations.

Preventing the Next Pandemic: Vaccine Diplomacy in a Time of Anti-Science


Peter J. Hotez - 2021
    From such twenty-first-century forces, we have seen declines in previous global health gains, with sharp increases in vaccine-preventable and neglected diseases on the Arabian Peninsula, in Venezuela, in parts of Africa, and even on the Gulf Coast of the United States. In Preventing the Next Pandemic, international vaccine scientist and tropical disease and coronavirus expert Peter J. Hotez, MD, PhD, argues that we can--and must--rely on vaccine diplomacy to address this new world order in disease and global health. Detailing his years in the lab developing new vaccines, Hotez also recounts his travels around the world to shape vaccine partnerships with people in countries both rich and poor in an attempt to head off major health problems. Building on the legacy of Dr. Albert Sabin, who developed the oral polio vaccine with Soviet scientists at the height of the Cold War, he explains how he is still working to refresh and redirect vaccine diplomacy toward neglected and newly emerging diseases.Hotez reveals how--during his Obama-era tenure as the US Science Envoy for the Middle East and North Africa, which coincided with both the rise in these geopolitical forces and climate change--he witnessed tropical infectious diseases and established vaccine partnerships that may still combat them up close. He explores why, since 2015, we've seen the decline of global cooperation and cohesion, to the detriment of those programs that are meant to benefit the most vulnerable people in the world. Unfortunately, Hotez asserts, these negative global events kick off a never-ending loop. Problems in a country may lead to disease outbreaks, but those outbreaks can lead to further problems--such as the impact of coronavirus on China's society and economy, which has been felt around the globe. Zeroing in on the sociopolitical and environmental factors that drive our most controversial and pressing global health concerns, Hotez proposes historically proven methods to soothe fraught international relations while preparing us for a safer, healthier future. He hammers home the importance of public engagement to communicate the urgency of embracing science during troubled times.Touching on a range of disease, from leishmaniasis, schistosomiasis, and Middle East Respiratory Syndrome (MERS) to COVID-19, Preventing the Next Pandemic has always been a timely goal, but it will be even more important in a COVID and post-COVID world.

Asperger's Children: The Origins of Autism in Nazi Vienna


Edith Sheffer - 2018
    But in this groundbreaking book, prize-winning historian Edith Sheffer exposes that Asperger was not only involved in the racial policies of Hitler’s Third Reich, he was complicit in the murder of children.As the Nazi regime slaughtered millions across Europe during World War Two, it sorted people according to race, religion, behavior, and physical condition for either treatment or elimination. Nazi psychiatrists targeted children with different kinds of minds—especially those thought to lack social skills—claiming the Reich had no place for them. Asperger and his colleagues endeavored to mold certain "autistic" children into productive citizens, while transferring others they deemed untreatable to Spiegelgrund, one of the Reich’s deadliest child-killing centers.In the first comprehensive history of the links between autism and Nazism, Sheffer uncovers how a diagnosis common today emerged from the atrocities of the Third Reich. With vivid storytelling and wide-ranging research, Asperger’s Children will move readers to rethink how societies assess, label, and treat those diagnosed with disabilities.

A Little History of the World


E.H. Gombrich - 1936
    Amazingly, he completed the task in an intense six weeks, and Eine kurze Weltgeschichte für junge Leser was published in Vienna to immediate success, and is now available in seventeen languages across the world. Toward the end of his long life, Gombrich embarked upon a revision and, at last, an English translation. A Little History of the World presents his lively and involving history to English-language readers for the first time. Superbly designed and freshly illustrated, this is a book to be savored and collected. In forty concise chapters, Gombrich tells the story of man from the stone age to the atomic bomb. In between emerges a colorful picture of wars and conquests, grand works of art, and the spread and limitations of science. This is a text dominated not by dates and facts, but by the sweep of mankind's experience across the centuries, a guide to humanity's achievements and an acute witness to its frailties. The product of a generous and humane sensibility, this timeless account makes intelligible the full span of human history.

Being Mortal: Medicine and What Matters in the End


Atul Gawande - 2014
    But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

Banana: The Fate of the Fruit That Changed the World


Dan Koeppel - 2007
    Americans eat more bananas than apples and oranges combined. In others parts of the world, bananas are what keep millions of people alive. But for all its ubiquity, the banana is surprisingly mysterious; nobody knows how bananas evolved or exactly where they originated. Rich cultural lore surrounds the fruit: In ancient translations of the Bible, the 'apple' consumed by Eve is actually a banana (it makes sense, doesn't it?). Entire Central American nations have been said to rise and fall over the banana. But the biggest mystery about the banana today is whether it will survive. A seedless fruit with a unique reproductive system, every banana is a genetic duplicate of the next, and therefore susceptible to the same blights. Today's yellow banana, the Cavendish, is increasingly threatened by such a blight -- and there's no cure in sight. Banana combines a pop-science journey around the globe, a fascinating tale of an iconic American business enterprise, and a look into the alternately tragic and hilarious banana subculture (one does exist) -- ultimately taking us to the high-tech labs where new bananas are literally being built in test tubes, in a race to save the world's most beloved fruit.

Our Oriental Heritage


Will Durant - 1935
    So the Durants embarked on an encyclopedic survey of all civilization, ancient and modern, Occidental and Oriental. The books: Our Oriental Heritage (Volume 1): Will Durant opens his massive survey of civilized history with a sweeping look at the Orient: the Egyptians, who perfected monumental architecture, medicine and mummification; the Babylonians, who developed astronomy and physics; the Judeans, who preserved their culture in the immortal books of the Old Testament; and the Persians, who ruled the largest empire in recorded history before Rome.The Life of Greece (Volume 2): Will Durant's survey of ancient Greece shows us the origins of democracy and the political legacy to the Western world; the golden age of Athens, its architecture, poetry, drama, sculpture and Olympic contests; the blossoming of philosophical thought amid a society still rooted in slavery and barbarism; and the mysterious lost island of Crete, land of the Minotaur and the Labyrinth. Caesar and Christ (Volume 3): Spanning a millenium in Roman history, the third volume in the Durants' series shows us a world-conquering Roman army, undefeated, unafraid and...vegeterian; Hannibal, who transported an army of elephants over the Alps to invade Rome; Julius Caesar, who brought Western Europe under Roman rule; the life and Passion of Christ; and the struggle of the rising church. The Age of Faith (Volume 4): Over 1,000 years, we meet the Christian ascetics and martyrs, including Simeon Stylites, who sat atop a pillar for 30 years, exposed to rain, sun, and snow, and rejoiced as worms ate his rotting flesh; the saints, including Augustine, the most influential philosopher of his age; Mohammed, the desert merchant who founded a religion that conquered one-third of the known world in two centuries; and the Italian poet Dante, whose sensibility marks the transition to the Renaissance. The Renaissance (Volume 5): In this volume, Will Durant examines the economic seeds -- the growth of industry, the rise of banking families, the conflicts of labor and capital -- for Italy's emergence as the first nation to feel the awakening of the modern mind. He follows the cultural flowering from Florence to Milan to Verona and eventually to Rome, allowing us to witness a colorful pageant of princes, queens, poets, painters, sculptors and architects. We see humanity moved boldly from a finite world to an infinite one. The Reformation (Volume 6): In Europe's tumultuous emergence from the Middle Ages, we encounter two rival popes fighting for control of a corrupt, cynical church; the Hundred Years' War and 13-year-old warrior Joan of Arc; Christopher Columbus' accidental discovery of the New World; and Martin Luther, who defied the pope and ultimately led Northern Europe into the age of individualism. The Age of Reason Begins (Volume 7): In one of Europe's most turbulent centuries, Philip II of Spain sees his "invincible" armada suffer defeat at the hands of England; Elizabeth I of England receives assistance from explorer Walter Raleigh and pirate Francis Drake; and new appeals for reason and science are exemplified in the ideas of Copernicus, Galileo and Descartes. The Age of Louis XIV (Volume 8): This installment is the biography of a period some consider the apex of modern European civilization. "Some centuries hence," Frederick the Great predicted to Voltaire, "they will translate the good authors of the time of Louis XIV as we translate those of the age of Pericles or Augustus." Those authors are lovingly treated here: Pascal and Fenelon, Racine and Boileau, Mme. de Sevigne and Mme. de La Fayette, and, above all, the philosopher-dramatist Moliere, exposing the vices and hypocrisies of the age. The Age of Voltaire (Volume 9): A biography of a great man and the period he embodied. We witness Voltaire's satiric work in the salons and the theater as well as his banishment to England. With him we view the complex relationships between nobility, clergy, bourgeoisie and peasantry in the France of Louis XV. We explore the music of Bach and the struggle between Frederick the Great and Maria Theresa of Austria. And finally we hear an imaginary discussion between Voltaire and Pope Benedict XIV on the significance and value of religion. Rousseau and Revolution (Volume 10): This volume ranges over a Europe in ferment, but centers on the passionate rebel-philosopher Jean-Jacques Rousseau, who contended with Voltaire for the mind of Europe. Rousseau condemned civilization as a disease, glorified the noble savage, proclaimed to the world with equal intensity his own love affairs and the natural rights of man, and became the patron saint of the French Revolution and social upheavals across the globe for two centuries. The Age of Napoleon (Volume 11): The final volume. Napoleon is the archetypical hero, whose restless, ambitious, and intelligent mind dominated his age and has never ceased to fascinate the world he helped fashion. Yet even Bonaparte is dwarfed by the age that took his name. For, the Durants have re-created the life, the history, the arts, the science, the politics, the philosophy, the manners and the morality, the very spirit of the turbulent epoch that began with the French Revolution, ended with the fall of the emperor and ushered in the modern world.

A Shot to Save the World: The Remarkable Race and Ground-Breaking Science Behind the Covid-19 Vaccines


Gregory Zuckerman - 2021
    Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist despised by his peers. Far from the limelight, each had spent years developing innovative vaccine approaches. Their work was met with skepticism and scorn. By 2020, these individuals had little proof of progress. Yet they and their colleagues wanted to be the ones to stop the virus holding the world hostage. They scrambled to turn their life’s work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough—and to beat each other for the glory that a vaccine guaranteed. A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist, Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It’s a story of courage, genius, and heroism. It’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.