Life's Greatest Secret: The Race to Crack the Genetic Code


Matthew Cobb - 2015
    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

Madness and Memory: The Discovery of Prions--A New Biological Principle of Disease


Stanley B. Prusiner - 2014
    Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

Homo Mysterious: Evolutionary Puzzles of Human Nature


David Philip Barash - 2012
    Barash, there are even more things that we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personalaspects of being human.Homo Mysterious examines a number of these evolutionary mysteries, exploring things that we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse. Why do women experience orgasm? Why do men have a shorterlifespan than women? Why does homosexuality exist? Why does religion exist in virtually every culture? Why do we have a fondness for the arts? Why do we have such large brains? And why does consciousness exist? Readers are plunged into an ocean of unknowns--the blank spots on the human evolutionarymap, the terra incognita of our own species--and are introduced to the major hypotheses that currently occupy scientists who are attempting to unravel each puzzle (including some solutions proposed here for the first time). Throughout the book, readers are invited to share the thrill of science atits cutting edge, a place where we know what we don't know, and, moreover, where we know enough to come up with some compelling and seductive explanations.Homo Mysterious is a guide to creative thought and future explorations, based on the best, most current thinking by evolutionary scientists. It captures the allure of the not-yet-known for those interested in stretching their scientific imaginations.

The Case of the Midwife Toad


Arthur Koestler - 1971
    It isn't surprising then that Koestler should hark back to the opprobrious case of Dr Paul Kammerer, an Austrian biologist whose controversial experiments on the evolutionary process (using among other amphibians the midwife toad, so named for its mating habits) were denounced as fraudulent in 1926 by an American herpetologist, G.K. Noble, in the pages of Nature-- whereupon Kammerer blew his brains out, seemingly confirming the old saw "confession is suicide & suicide is confession." But Koestler's investigation, begun as a study of a scientist who betrayed his commitment to truth, indicates that Kammerer, far from being a laboratory quisling, was probably innocent; a victim of an unknown colleague's machinations to discredit his work & therefore in the larger sense a casualty of the still unresolved war between the nco-Darwinist evolutionists who support the random mutation theory & the heretical Lamarckians who maintain (as did Kammerer's experiments) that acquired characteristics can be transmitted from one generation to another. "I did not start with the intention to rehabilitate Paul Kammerer," says Koestler, "but I ended up with an attempt to do so." In the course of that effort he uses his skill as both inventive fantast & experienced researcher to give the midwife toad case a sense of drama & veracity. Those who found The Double Helix satisfying will enjoy this one too, no matter if they agree with Koestler's conclusions.--Kirkus (edited)

Suspended In Language: Niels Bohr's Life, Discoveries, And The Century He Shaped


Jim Ottaviani - 2004
    His friends and enemies agreed: Niels Bohr was more than the father of quantum mechanics - he was one of the most important figures of the 20th century. The Tony Award-winning Broadway play Copenhagen barely scratched the surface... Suspended in Language tells the complete story of Niels Bohr's amazing life, discoveries, and his pervasive influence on science, philosophy, and politics. Told in an engaging and accessible mixture of text and comics, it includes a full color supplement on how to teleport just like the pros do-and why you might not want to!

Exploring the History of Medicine: From the Ancient Physicians of Pharaoh to Genetic Engineering


John Hudson Tiner - 1999
    Quality of life has improved dramatically in the last few decades alone, and the future is bright. But students must not forget that God provided humans with minds and resources to bring about these advances.A biblical perspective of healing and the use of medicine provides the best foundation for treating diseases and injury. In Exploring the World of Medicine, author John Hudson Tiner reveals the spectacular discoveries that started with men and women who used their abilities to better mankind and give glory to God.The fascinating history of medicine comes alive in this book, providing students with a healthy dose of facts, mini-biographies, and vintage illustrations. Includes chapter tests and index.

Anatomy 101: From Muscles and Bones to Organs and Systems, Your Guide to How the Human Body Works


Kevin Langford - 2015
    Too often, textbooks turn the fascinating systems, processes, and figures of anatomy into tedious discourse that even Leonardo Da Vinci would reject. This easy-to-read guide cuts out the boring details, and instead, provides you with a compelling lesson in anatomy. Covering every aspect of anatomical development and physiology, each chapter details the different parts of the human body, how systems are formed, and disorders that could disrupt bodily functions. You'll unravel the mysteries of anatomy with unique, accessible elements like: Detailed charts of each system in the body Illustrations of cross sections Unique profiles of the most influential figures in medical history From cell chemistry to the respiratory system, Anatomy 101 is packed with hundreds of entertaining facts that you can't get anywhere else!

Who Was Adam?: A Creation Model Approach to the Origins of Man


Fazale Rana - 2005
    Did humans emerge through evolutionary processes from an ape-like ancestor or are we God's creation? A comparison of scientific models provides stunning insights and a framework to test emerging evidence.

Undeniable: Evolution and the Science of Creation


Bill Nye - 2014
    In this book, he expands the points he has made, and claims that this debate is not so much about religion versus science, as about the nature of science itself. With infectious enthusiasm, he reveals the mechanics of evolutionary theory, explains how it is rooted in the testable and verifiable scientific method, and why it is therefore a sound explanation of our beginning. He argues passionately that to continue to assert otherwise, to continue to insist that creationism has a place in the science classroom is harmful not only to our children, but to the future of the greater world as well.

Genesis: The Deep Origin of Societies


Edward O. Wilson - 2019
    Of these, Wilson demonstrates that at least seventeen—among them the African naked mole rat and the sponge- dwelling shrimp—have been found to have advanced societies based on altruism and cooperation.Whether writing about midges who “dance about like acrobats” or schools of anchovies who protectively huddle “to appear like a gigantic fish,” or proposing that human society owes a debt of gratitude to “postmenopausal grandmothers” and “childless homosexuals,” Genesis is a pithy yet path-breaking work of evolutionary theory, braiding twenty-first-century scientific theory with the lyrical biological and humanistic observations for which Wilson is known.

The Ultimate Fate Of The Universe


Jamal Nazrul Islam - 1983
    To understand the universe in the far future, we must first describe its present state and structure on the grand scale, and how its present properties arose. Dr Islam explains these topics in an accessible way in the first part of the book. From this background he speculates about the future evolution of the universe and predicts the major changes that will occur. The author has largely avoided mathematical formalism and therefore the book is well suited to general readers with a modest background knowledge of physics and astronomy.

The Death of Cancer: After Fifty Years on the Front Lines of Medicine, a Pioneering Oncologist Reveals Why the War on Cancer Is Winnable--and How We Can Get There


Vincent T. DeVita Jr. - 2015
    But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible.Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers.With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

The Mathematics of Life


Ian Stewart - 2011
    Within the past ten years, however, mathematicians have proven that they hold the key to unlocking the mysteries of our world--and ourselves. In The Mathematics of Life, Ian Stewart provides a fascinating overview of the vital but little-recognized role mathematics has played in pulling back the curtain on the hidden complexities of the natural world--and how its contribution will be even more vital in the years ahead. In his characteristically clear and entertaining fashion, Stewart explains how mathematicians and biologists have come to work together on some of the most difficult scientific problems that the human race has ever tackled, including the nature and origin of life itself.

The Spanish Flu: A History from Beginning to End


Hourly History - 2020
    It infected nearly one-third of the world’s population and killed ten percent of those it struck. In its wake, schools and businesses closed, hospitals became overwhelmed, and the sick spilled out into makeshift care centers in public spaces. Policemen, public transportation workers, and everyday citizens in face masks were a common—and eerie—sight. Yet, discussion of this global pandemic often takes a backseat to World War I and other contemporary events.

Biology For Dummies


Rene Fester Kratz - 2010
    Wouldn't it be great to have a single source of quick answers to all our questions about how living things work? Now there is.From molecules to animals, cells to ecosystems, Biology For Dummies, 2nd Edition answers all your questions about how living things work.Written in plain English and packed with dozens of illustrations, quick-reference Cheat Sheets, and helpful tables and diagrams, it cuts right to the chase with fast-paced, easy-to-absorb explanations of the life processes common to all organisms. More than 20% new and updated content, including a substantial overhaul to the organization of topics to make it a friendly classroom supplement Coverage of the most recent developments and discoveries in evolutionary, reproductive, and ecological biology Includes practical, up-to-date examples Whether you're currently enrolled in a biology class or just want to know more about this fascinating and ever-evolving field of study, this engaging guide will give you a grip on complex biology concepts and unlock the mysteries of how life works in no time.