They discuss how scientists are working out the clockwork mechanisms and what governs them, and they describe how organisms measure different intervals of time, how they are adapted to various cycles, and how light coordinates the time within to the external world. They review problems that can be caused by malfunctioning biological clocks—including jet lag, seasonal affective disorder, and depression. And they warn that although new drugs are being promoted to allow us to stay awake for longer periods, a 24/7 lifestyle can have a harmful impact on our health, both as individuals and as a society.

    It contains accounts by Richard 'The Iceman' Kuklinski, the contract killer who claimed to have murdered over 200 people in a career lasting 43 years.

    F. Skinner and the legend of a child raised in a box, Slater takes us from a deep empathy with Stanley Milgram's obedience subjects to a funny and disturbing re-creation of an experiment questioning the validity of psychiatric diagnosis. Previously described only in academic journals and textbooks, these often daring experiments have never before been narrated as stories, chock-full of plot, wit, personality, and theme.

    That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research—the Philadelphia chromosome. This book charts not only that landmark discovery, but also—for the first time, all in one place—the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings extensive original reporting to this book, including interviews with more than thirty-five people with a direct role in this story. Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 70,000 people worldwide who are diagnosed with CML each year. Chief among them is researcher and oncologist Dr. Brian Druker, whose dedication to his patients fueled his quest to do everything within his power to save them.The Philadelphia Chromosome helps us to fully understand and appreciate just how pathbreaking, hard-won, and consequential are the achievements it recounts—and to understand the principles behind much of today’s most important cancer research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

    While they're at it, they helpfully demystify many complicated things we do know about, from quarks and neutrinos to gravitational waves and exploding black holes. With equal doses of humor and delight, they invite us to see the universe as a vast expanse of mostly uncharted territory that's still ours to explore.This entertaining illustrated science primer is the perfect book for anyone who's curious about all the big questions physicists are still trying to answer.

    Written by Curie’s daughter, the renowned international activist Eve Curie, this biography chronicles Curie’s legendary achievements in science, including her pioneering efforts in the study of radioactivity and her two Nobel Prizes in Physics and Chemistry. It also spotlights her remarkable life, from her childhood in Poland, to her storybook Parisian marriage to fellow scientist Pierre Curie, to her tragic death from the very radium that brought her fame. Now updated with an eloquent, rousing introduction by best-selling author Natalie Angier, this timeless biography celebrates an astonishing mind and a extraordinary woman’s life.

    What will happen if humanity makes contact with another civilization on a different planet? In The Contact Paradox, space journalist Keith Cooper tackles some of the myths and assumptions that underlie SETI--the Search for Extraterrestrial Intelligence.In 1974 a message was beamed towards the stars by the giant Arecibo telescope in Puerto Rico, a brief blast of radio waves designed to alert extraterrestrial civilizations to our existence. Of course, we don't know if such civilizations really exist. But for the past six decades a small cadre of researchers have been on a quest to find out, as part of SETI, the search for extraterrestrial intelligence.The silence from the stars is prompting some researchers, inspired by the Arecibo transmission, to transmit more messages into space, in an effort to provoke a response from any civilizations out there that might otherwise be staying quiet. However, the act of transmitting raises troubling questions about the process of contact. We look for qualities such as altruism and intelligence in extraterrestrial life, but what do these mean to humankind? Can we learn something about our own history when we explore what happens when two civilizations come into contact? Finally, do the answers tell us that it is safe to transmit, even though we know nothing about extraterrestrial life, or as Stephen Hawking argued, are we placing humanity in jeopardy by doing so?In The Contact Paradox, author Keith Cooper looks at how far SETI has come since its modest beginnings, and where it is going, by speaking to the leading names in the field and beyond. SETI forces us to confront our nature in a way that we seldom have before--where did we come from, where are we going, and who are we in the cosmic context of things? This book considers the assumptions that we make in our search for extraterrestrial life, and explores how those assumptions can teach us about ourselves.

    Carl Linnaeus's controversial new system for classifying plants based on their sexual characteristics, as well as his use of language resonating with erotic allusions, provoked intense public debate over the morality of botanical study. And the renowned Tahitian exploits of Joseph Banks--whose trousers were reportedly stolen while he was inside the tent of Queen Oberea of Tahiti--reinforced scandalous associations with the field. Yet Linnaeus and Banks became powerful political and scientific figures who were able to promote botanical exploration alongside the exploitation of territories, peoples, and natural resources. Sex, Botany, and Empire explores the entwined destinies of these two men and how their influence served both science and imperialism.Patricia Fara reveals how Enlightenment botany, under the veil of rationality, manifested a drive to conquer, subdue, and deflower--all in the name of British empire. Linnaeus trained his traveling disciples in a double mission--to bring back specimens for the benefit of the Swedish economy and to spread the gospel of Linnaean taxonomy. Based in London at the hub of an international exchange and correspondence network, Banks ensured that Linnaeus's ideas became established throughout the world. As the president of the Royal Society for more than forty years, Banks revolutionized British science, and his innovations placed science at the heart of trade and politics. He made it a policy to collect and control resources not only for the sake of knowledge but also for the advancement of the empire. Although Linnaeus is often celebrated as modern botany's true founder, Banks has had a greater long-term impact. It was Banks who ensured that science and imperialism flourished together, and it was he who first forged the interdependent relationship between scientific inquiry and the state that endures to this day.

    “I walk with a new spring in my step and I look at life through physics-colored eyes,” wrote one such fan. When Lewin’s lectures were made available online, he became an instant YouTube celebrity, and The New York Times declared, “Walter Lewin delivers his lectures with the panache of Julia Child bringing French cooking to amateurs and the zany theatricality of YouTube’s greatest hits.” For more than thirty years as a beloved professor at the Massachusetts Institute of Technology, Lewin honed his singular craft of making physics not only accessible but truly fun, whether putting his head in the path of a wrecking ball, supercharging himself with three hundred thousand volts of electricity, or demonstrating why the sky is blue and why clouds are white. Now, as Carl Sagan did for astronomy and Brian Green did for cosmology, Lewin takes readers on a marvelous journey in For the Love of Physics, opening our eyes as never before to the amazing beauty and power with which physics can reveal the hidden workings of the world all around us. “I introduce people to their own world,” writes Lewin, “the world they live in and are familiar with but don’t approach like a physicist—yet.” Could it be true that we are shorter standing up than lying down? Why can we snorkel no deeper than about one foot below the surface? Why are the colors of a rainbow always in the same order, and would it be possible to put our hand out and touch one? Whether introducing why the air smells so fresh after a lightning storm, why we briefly lose (and gain) weight when we ride in an elevator, or what the big bang would have sounded like had anyone existed to hear it, Lewin never ceases to surprise and delight with the extraordinary ability of physics to answer even the most elusive questions. Recounting his own exciting discoveries as a pioneer in the field of X-ray astronomy—arriving at MIT right at the start of an astonishing revolution in astronomy—he also brings to life the power of physics to reach into the vastness of space and unveil exotic uncharted territories, from the marvels of a supernova explosion in the Large Magellanic Cloud to the unseeable depths of black holes. “For me,” Lewin writes, “physics is a way of seeing—the spectacular and the mundane, the immense and the minute—as a beautiful, thrillingly interwoven whole.” His wonderfully inventive and vivid ways of introducing us to the revelations of physics impart to us a new appreciation of the remarkable beauty and intricate harmonies of the forces that govern our lives.

    More than a possibility, it is becoming a necessity: whether our hand is forced by climate change and resource depletion or whether future catastrophes compel us to abandon Earth, one day we will make our homes among the stars.World-renowned physicist and futurist Michio Kaku explores in rich, accessible detail how humanity might gradually develop a sustainable civilization in outer space. With his trademark storytelling verve, Kaku shows us how science fiction is becoming reality: mind-boggling developments in robotics, nanotechnology, and biotechnology could enable us to build habitable cities on Mars; nearby stars might be reached by microscopic spaceships sailing through space on laser beams; and technology might one day allow us to transcend our physical bodies entirely.With irrepressible enthusiasm and wonder, Dr. Kaku takes readers on a fascinating journey to a future in which humanity could finally fulfil its long-awaited destiny among the stars - and perhaps even achieve immortality.

    Someday, we know, we will all die. And, we know, so too will the universe itself.Until the End of Time is Brian Greene's breathtaking new exploration of the cosmos and our quest to understand it. Greene takes us on a journey across time, from our most refined understanding of the universe's beginning, to the closest science can take us to the very end. He explores how life and mind emerged from the initial chaos, and how our minds, in coming to understand their own impermanence, seek in different ways to give meaning to experience: in story, myth, religion, creative expression, science, the quest for truth, and our longing for the timeless, or eternal. Through a series of nested stories that explain distinct but interwoven layers of reality-from the quantum mechanics to consciousness to black holes-Greene provides us with a clearer sense of how we came to be, a finer picture of where we are now, and a firmer understanding of where we are headed.Yet all this understanding, which arose with the emergence of life, will dissolve with its conclusion. Which leaves us with one realization: during our brief moment in the sun, we are tasked with the charge of finding our own meaning.Let us embark.

    When temperatures drop below 56°F, tin crumbles into powder. Were the soldiers of the Grande Armée acutee fatally weakened by cold because the buttons of their uniforms fell apart? How different our world might be if tin did not disintegrate at low temperatures and the French had continued their eastward expansion! This fascinating book tells the stories of seventeen molecules that, like the tin of those buttons, greatly influenced the course of history. These molecules provided the impetus for early exploration and made possible the ensuing voyages of discovery. They resulted in grand feats of engineering and spurred advances in medicine; lie behind changes in gender roles, in law, and in the environment; and have determined what we today eat, drink, and wear. Showing how a change as small as the position of an atom can lead to enormous differences in the properties of a substance, the authors reveal the astonishing chemical connections among seemingly unrelated events. Napoleon's Buttons offers a novel way to understand how our contemporary world works and how our civilization has been shaped over time.

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    Such age-old stories as the tragic love of Orpheus and Eurydice or Demeter’s loss of her daughter, Persephone, resonate strongly with readers even today. In this book the rousing adventures of the heroes Herakles, Theseus, and Perseus are intertwined with the tragedies of immortal Prometheus and mortal Oedipus, the amorous escapades of Zeus, the trickery of Hermes, and the ecstasy of Dionysus. In-depth introductions to each section deepen your understanding of the myths—and heighten your reading pleasure.Presented in simple yet elegant prose, these tales emerge in brilliant new life. From the creation battle of the gods and Titans to Odysseus’ return home from the Trojan War, this indispensable volume contains fifty-six legendary stories—handed down from generations past—that will continue to captivate readers for generations to come.

    But are there limits to what we can discover about our physical universe?In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data.Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding?In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there’s anything we truly cannot know.