The Addictive Brain


Thad A. Polk - 2015
    Whether it’s a friend who can’t quit smoking, a colleague afflicted with alcoholism, or a relative abusing prescription drugs, we all know someone who suffers from some form of addiction—we may even have an addiction ourselves. By some estimates, roughly one in four Americans might be considered addicts. On the other hand, many of us use substances such as alcohol recreationally, without suffering the physical or psychological symptoms of addiction. So what is the difference between drug use, abuse, and clinical addiction? What causes addictions? What happens when your brain is on drugs, and why do addicts behave the way they do?12 Lectures 1. Addiction 101 2. The Psychology and Neuroscience of Reward 3. How Addiction Hijacks the Brain 4. Genetics: Born to Be an Addict? 5. Your Brain on Drugs 6. Why We Crave Coffee and Cigarettes 7. Alcohol: Social Lubricant or Drug of Abuse? 8. The Science of Marijuana 9. Stimulants: From Cocaine to Ritalin 10. The Science of Poppies, Pleasure, and Pain 11. The Gambler's Brain 12. Junk Food, Porn, Video Games: Addictions?Listening Length: 6 hours and 23 minutes

Genes vs Cultures vs Consciousness: A Brief Story of Our Computational Minds


Andres Campero - 2019
    It touches on its evolutionary development, its algorithmic nature and its scientific history by bridging ideas across Neuroscience, Computer Science, Biotechnology, Evolutionary History, Cognitive Science, Political Philosophy, and Artificial Intelligence.Never before had there been nearly as many scientists, resources or productive research focused on these topics, and humanity has achieved some understanding and some clarification. With the speed of progress it is timely to communicate an overreaching perspective, this book puts an emphasis on conveying the essential questions and what we know about their answers in a simple, clear and exciting way.Humans, along with the first RNA molecules, the first life forms, the first brains, the first conscious animals, the first societies and the first artificial agents constitute an amazing and crucial development in a path of increasingly complex computational intelligence. And yet, we occupy a minuscule time period in the history of Earth, a history that has been written by Genes, by Cultures and by Consciousnesses. If we abandon our anthropomorphic bias it becomes obvious that Humans are not so special after all. We are an important but short and transitory step among many others in a bigger story. The story of our computational minds, which is ours but not only ours. What is the relationship between computation, cognition and everything else? What is life and how did it originate? What is the role of culture in human minds? What do we know about the algorithmic nature of the mind, can we engineer it? What is the computational explanation of consciousness? What are some possible future steps in the evolution of minds? The underlying thread is the computational nature of the Mind which results from the mixture of Genes, Cultures and Consciousness. While these three interact in complex ways, they are ultimately computational systems on their own which appeared at different stages of history and which follow their own selective processes operating at different time scales. As technology progresses, the distinction between the three components materializes and will be a key determinant of the future.Among the many topics covered are the origin of life, the concept of computation and its relation to Turing Machines, cultural evolution and the notion of a Selfish Meme, free will and determinism, moral relativity, the hard problem of consciousness, the different theories of concepts from the perspective of cognitive science, the current status of AI and Machine Learning including the symbolic vs sub-symbolic dichotomy, the contrast between logical reasoning and neural networks, and the recent history of Deep Learning, Geoffrey Hinton, DeepMind and its algorithm AlphaGo. It also develops on the history of science and looks into the possible future building on the work of authors like Daniel Dennett, Yuval Harari, Richard Dawkins, Francis Crick, George Church, David Chalmers, Susan Carey, Stanislas Dehaene, Robert Boyd, Joseph Henrich, Daniel Kahneman, Moran Cerf, Josh Tenenbaum, David Deutsch, Steven Pinker, Ray Kurzweil, John von Neumann, Herbert Simon and many more. Andres Campero is a researcher and PhD student at the Brain and Cognitive Sciences Department and at the Computer Science and Artificial Intelligence Laboratory at the Massachusetts Institute of Technology (MIT).

Steve Jobs Graduation Speech


Steve Jobs - 2011
    Here, word for word is that amazing speech to inspire you to find what it is that you "Love".

Habits of a Happy Brain: Retrain Your Brain to Boost Your Serotonin, Dopamine, Oxytocin, Endorphin Levels


Loretta Graziano Breuning - 2015
    Each page offers simple activities that help you understand the roles of your “happy chemicals”—serotonin, dopamine, oxytocin, and endorphin. You’ll also learn how to build new habits by rerouting the electricity in your brain to flow down a new pathway, making it even easier to trigger these happy chemicals and increase feelings of satisfaction when you need them most. Filled with dozens of exercises that will help you reprogram your brain, Habits of a Happy Brain shows you how to live a happier, healthier life!

The Science of Fear: Why We Fear the Things We Shouldn't--and Put Ourselves in Greater Danger


Daniel Gardner - 2008
    And yet, we are the safest and healthiest humans in history. Irrational fear seems to be taking over, often with tragic results. For example, in the months after 9/11, when people decided to drive instead of fly—believing they were avoiding risk—road deaths rose by more than 1,500. In this fascinating, lucid, and thoroughly entertaining examination of how humans process risk, journalist Dan Gardner had the exclusive cooperation of Paul Slovic, the world renowned risk-science pioneer, as he reveals how our hunter gatherer brains struggle to make sense of a world utterly unlike the one that made them. Filled with illuminating real world examples, interviews with experts, and fast-paced, lean storytelling, The Science of Fear shows why it is truer than ever that the worst thing we have to fear is fear itself.

Just Babies: The Origins of Good and Evil


Paul Bloom - 2013
    Many of us take for granted that babies are born selfish and that it is the role of society—and especially parents—to transform them from little sociopaths into civilized beings. In Just Babies, Paul Bloom argues that humans are in fact hardwired with a sense of morality. Drawing on groundbreaking research at Yale, Bloom demonstrates that, even before they can speak or walk, babies judge the goodness and badness of others’ actions; feel empathy and compassion; act to soothe those in distress; and have a rudimentary sense of justice.Still, this innate morality is limited, sometimes tragically. We are naturally hostile to strangers, prone to parochialism and bigotry. Bringing together insights from psychology, behavioral economics, evolutionary biology, and philosophy, Bloom explores how we have come to surpass these limitations. Along the way, he examines the morality of chimpanzees, violent psychopaths, religious extremists, and Ivy League professors, and explores our often puzzling moral feelings about sex, politics, religion, and race.

Memoirs of an Addicted Brain: A Neuroscientist Examines his Former Life on Drugs


Marc Lewis - 2011
    This cycle is at the root of all addictions, addictions to drugs, sex, love, cigarettes, soap operas, wealth, and wisdom itself. But why should this be so? Why are we desperate for what we don't have, or can't have, often at great cost to what we do have, thereby risking our peace and contentment, our safety, and even our lives?"The answer, says Dr. Marc Lewis, lies in the structure and function of the human brain. Marc Lewis is a distinguished neuroscientist. And, for many years, he was a drug addict himself, dependent on a series of dangerous substances, from LSD to heroin. His narrative moves back and forth between the often dark, compellingly recounted story of his relationship with drugs and a revelatory analysis of what was going on in his brain. He shows how drugs speak to the brain - which is designed to seek rewards and soothe pain - in its own language. He shows in detail the neural mechanics of a variety of powerful drugs and of the onset of addiction, itself a distortion of normal perception.Dr. Lewis freed himself from addiction and ended up studying it. At the age of 30 he traded in his pharmaceutical supplies for the life of a graduate student, eventually becoming a professor of developmental psychology, and then of neuroscience - his field for the last 12 years. This is the story of his journey, seen from the inside out.

Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America


Robert Whitaker - 2010
    What is going on? Anatomy of an Epidemic challenges readers to think through that question themselves. First, Whitaker investigates what is known today about the biological causes of mental disorders. Do psychiatric medications fix “chemical imbalances” in the brain, or do they, in fact, create them? Researchers spent decades studying that question, and by the late 1980s, they had their answer. Readers will be startled—and dismayed—to discover what was reported in the scientific journals. Then comes the scientific query at the heart of this book: During the past fifty years, when investigators looked at how psychiatric drugs affected long-term outcomes, what did they find? Did they discover that the drugs help people stay well? Function better? Enjoy good physical health? Or did they find that these medications, for some paradoxical reason, increase the likelihood that people will become chronically ill, less able to function well, more prone to physical illness?  This is the first book to look at the merits of psychiatric medications through the prism of long-term results. Are long-term recovery rates higher for medicated or unmedicated schizophrenia patients? Does taking an antidepressant decrease or increase the risk that a depressed person will become disabled by the disorder? Do bipolar patients fare better today than they did forty years ago, or much worse? When the National Institute of Mental Health (NIMH) studied the long-term outcomes of children with ADHD, did they determine that stimulants provide any benefit?  By the end of this review of the outcomes literature, readers are certain to have a haunting question of their own: Why have the results from these long-term studies—all of which point to the same startling conclusion—been kept from the public?  In this compelling history, Whitaker also tells the personal stories of children and adults swept up in this epidemic. Finally, he reports on innovative programs of psychiatric care in Europe and the United States that are producing good long-term outcomes. Our nation has been hit by an epidemic of disabling mental illness, and yet, as Anatomy of an Epidemic reveals, the medical blueprints for curbing that epidemic have already been drawn up.

The Invisible Gorilla: And Other Ways Our Intuitions Deceive Us


Christopher Chabris - 2010
    In The Invisible Gorilla, Christopher Chabris and Daniel Simons, creators of one of psychology’s most famous experiments, use remarkable stories and counterintuitive scientific findings to demonstrate an important truth: Our minds don’t work the way we think they do. We think we see ourselves and the world as they really are, but we’re actually missing a whole lot.Again and again, we think we experience and understand the world as it is, but our thoughts are beset by everyday illusions. We write traffic laws and build criminal cases on the assumption that people will notice when something unusual happens right in front of them. We’re sure we know where we were on 9/11, falsely believing that vivid memories are seared into our minds with perfect fidelity. And as a society, we spend billions on devices to train our brains because we’re continually tempted by the lure of quick fixes and effortless self-improvement.  The Invisible Gorilla reveals the myriad ways that our intuitions can deceive us, but it’s much more than a catalog of human failings. Chabris and Simons explain why we succumb to these everyday illusions and what we can do to inoculate ourselves against their effects. Ultimately, the book provides a kind of x-ray vision into our own minds, making it possible to pierce the veil of illusions that clouds our thoughts and to think clearly for perhaps the first time.

Why Us?: How Science Rediscovered the Mystery of Ourselves


James Le Fanu - 2009
    The first is the astonishing achievement of the Human Genome Project, which, it was anticipated, would identify the genetic basis of those characteristics that distinguish humans from their primate cousins. The second is the phenomenal advance in brain imaging that now permits neuroscientists to observe the brain 'in action' and thus account for the remarkable properties of the human mind.But that is not how it has turned out. It is simply not possible to get from the monotonous sequence of genes along the Double Helix to the near infinite diversity of the living world, nor to translate the electrical firing of the brain into the creativity of the human mind. This is not a matter of not knowing all the facts. Rather, science has inadvertently discovered that its theories are insufficient to conjure the wonder of the human experience from the bare bones of our genes and brains.We stand on the brink of a tectonic shift in our understanding of ourselves that will witness the rediscovery of the central premise of Western philosophy that there is 'more than we can know'. Lucid, compelling and utterly engaging, ‘Why Us?’ offers a convincing and provocative vision of the new science of being human.

Why Do People Get Ill


David Corfield - 2007
    With case studies and advice for a fitter life, this is an intriguing and thought-provoking book, one which should be read by anyone who cares about their wellbeing.

Mirrors in the Brain: How Our Minds Share Actions and Emotions


Giacomo Rizzolatti - 2006
    When we see someone in distress, we share that distress. When we see a great actor, musician or sportsperson perform at the peak of their abilities, it can feel like we are experiencing just something of what they are experiencing. Yet only recently, with the discover of mirror neurons, has it become clear just how this powerful sharing of experience is realised within the human brain. This book provides, for the first time, a systematic overview of mirror neurons, written by the man who first discovered them.In the early 1990's Giacomo Rizzolatti and his co-workers at the University of Parma discovered that some neurons had a surprising property. They responded not only when a subject performed a given action, but also when the subject observed someone else performing that same action. These results had a deep impact on cognitive neuroscience, leading the neuroscientist vs Ramachandran to predict that 'mirror neurons would do for psychology what DNA did for biology'. The unexpected properties of these neurons have not only attracted the attention of neuroscientists. Many sociologists, anthropologists, and even artists have been fascinated by mirror neurons. The director and playwright Peter Brook stated that mirror neurons throw new light on the mysterious link that is created each time actors take the stage and face their audience - the sight of a great actor performing activates in the brain of the observer the very same areas that are active in the performer - including both their actions and their emotions.Written in a highly accessible style, that conveys something of the excitement of this groundbreaking theory, Mirrors in the Brain is the definitive account of one the major scientific discoveries of the past 50 years.

Keep Sharp: Build a Better Brain at Any Age


Sanjay Gupta - 2020
    Throughout our life, we look for ways to keep our mind sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age. Keep Sharp debunks common myths about aging and cognitive decline, explores whether there’s a “best” diet or exercise regimen for the brain, and explains whether it’s healthier to play video games that test memory and processing speed, or to engage in more social interaction. Discover what we can learn from “super-brained” people who are in their eighties and nineties with no signs of slowing down—and whether there are truly any benefits to drugs, supplements, and vitamins. Dr. Gupta also addresses brain disease, particularly Alzheimer’s, answers all your questions about the signs and symptoms, and shows how to ward against it and stay healthy while caring for a partner in cognitive decline. He likewise provides you with a personalized twelve-week program featuring practical strategies to strengthen your brain every day. Keep Sharp is the only owner’s manual you’ll need to keep your brain young and healthy regardless of your age!

The Mind-Gut Connection: How the Astonishing Dialogue Taking Place in Our Bodies Impacts Health, Weight, and Mood


Emeran Mayer - 2015
    While the dialogue between the gut and the brain has been recognized by ancient healing traditions, including Ayurvedic and Chinese medicine, Western medicine has failed to appreciate the complexity of how the brain, gut, and more recently, the microbiome—the microorganisms that live inside us—communicate with one another. In The Mind-Gut Connection, Dr. Emeran Mayer, executive director of the UCLA Center for Neurobiology of Stress, offers a revolutionary look at this developing science, teaching us how to harness the power of the mind-gut connection to take charge of our health.The Mind-Gut Connection shows how to keep the brain-gut communication clear and balanced to:• heal the gut by focusing on a plant-based diet• balance the microbiome by consuming fermented foods and probiotics, fasting, and cutting out sugar and processed foods• promote weight loss by detoxifying and creating healthy digestion and maximum nutrient absorption• boost immunity and prevent the onset of neurological diseases such as Parkinson’s andAlzheimer’s• generate a happier mindset and reduce fatigue, moodiness, anxiety, and depression• prevent and heal GI disorders such as leaky gut syndrome, food sensitivities and allergies, and IBS, as well as digestive discomfort such as heartburn and bloating• and much more.

A Billion Wicked Thoughts: What the World's Largest Experiment Reveals about Human Desire


Ogi Ogas - 2011
     For his groundbreaking sexual research, Alfred Kinsey and his team interviewed 18,000 people, relying on them to honestly report their most intimate experiences. Using the Internet, the neuroscientists Ogas and Gaddam quietly observed the raw sexual behaviors of half a billion people. By combining their observations with neuroscience and animal research, these two young neuroscientists finally answer the long-disputed question: what do people really like? Ogas and Gaddam's findings are transforming the way scientists and therapists think about sexual desire. In their startling book, Ogas and Gaddam analyze a "billion wicked thoughts" on the Internet: a billion Web searches, a million individual search histories, a million erotic stories, a half-million erotic videos, a million Web sites, millions of online personal ads, and many other enormous sources of sexual data in order to understand the true differences between male and female desires, including: ?Men and women have hardwired sexual cues analogous to our hardwired tastes-there are sexual versions of sweet, sour, salty, savory, and bitter. But men and women are wired with different sets of cues. ?The male sexual brain resembles a reckless hunter, while the female sexual brain resembles a cautious detective agency. ?Men form their sexual interests during adolescence and rarely change. Women's sexual interests are plastic and change frequently. ?The male sexual brain is an "or gate": A single stimulus can arouse it. The female sexual brain is an "and gate": It requires many simultaneous stimuli to arouse it. ?When it comes to sexual arousal, men prefer overweight women to underweight women, and a significant number of men seek out erotic images of women in their 40s, 50s, and 60s. ?Women enjoy writing and sharing erotic stories with other women. The fastest growing genre of erotic stories for women are stories about two heterosexual men having sex. ?Though the male sexual brain is much more different from the female sexual brain than is commonly believed, the sexual brain of gay men is virtually identical to that of straight men. Featuring cutting-edge, jaw-dropping science, this wildly entertaining and controversial book helps readers understand their partner's sexual desires with a depth of knowledge unavailable from any other source. Its fascinating and occasionally disturbing findings will rock our modern understanding of sexuality, just as Kinsey's reports did sixty years ago.