Tell Me Where It Hurts: A Day of Humor, Healing, and Hope in My Life as an Animal Surgeon

    On Instagram, his uproarious videos have entertained millions and have made him a global celebrity. Now, he brings his bon vivance to the page with this collection of intimate and sassy essays.Bursting with color and life, dripping with his puckish Southern charm, How Y’all Doing? is Leslie doing what Leslie does best: telling stories that make us laugh and lift our spirits even in the darkest days. Whether he’s writing about his brush with a group of ruffians in a West Hollywood Starbucks, or an unexpected phone call from legendary Hollywood start Debbie Reynolds, Leslie infuses each story with his fresh and saucy humor and pure heart.How Y’all Doing? is an authentic, warm, and joyful portrait of an American Sweetheart— a Southern Baptist celebutante, first-rate raconteur, and keen observer of the odd side of life whose quirky wit rivals the likes of Amy Sedaris, Jenny Lawson, David Rakoff, and Sarah Vowell.

    You'd be wrong. When he buys a beach house on the Carolina coast, Sedaris envisions long, relaxing vacations spent playing board games and lounging in the sun with those he loves most. And life at the Sea Section, as he names the vacation home, is exactly as idyllic as he imagined, except for one tiny, vexing realization: it's impossible to take a vacation from yourself.With Calypso, Sedaris sets his formidable powers of observation toward middle age and mortality. Make no mistake: these stories are very, very funny--it's a book that can make you laugh 'til you snort, the way only family can. Sedaris's powers of observation have never been sharper, and his ability to shock readers into laughter unparalleled. But much of the comedy here is born out of that vertiginous moment when your own body betrays you and you realize that the story of your life is made up of more past than future.This is beach reading for people who detest beaches, required reading for those who loathe small talk and love a good tumor joke. Calypso is simultaneously Sedaris's darkest and warmest book yet--and it just might be his very best.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Tackling the job with skills picked up along the way and enough Redbull to sink a battleship. The stories are real. The patients are real, and the emotions are real. Things I would tell my former student-self: You are going to laugh. You are going to cry. You are going to be scared. You are going to want to quit. You will have PTSD. You are going to see death. But hold on, you got this. It's just a few bumps.

    FOCUS takes readers into Ingrid’s world as she faces the crippling fear of not being able to see her two young daughters grow up, of becoming a burden to her husband, of losing the career she loves, and of being robbed of the independence that defines her.Ultimately, FOCUS is about Ingrid’s quest to fix her eyes that ends up fixing her life. Through an eight-year journey marked by a trip to South Africa to write about AIDS orphans, a four-day visit with a doctor who focuses on whole-body health, a relationship-changing confrontation with her husband and a life-changing lesson from her daughters, Ingrid learns to embrace the moment and see what counts—something no amount of vision loss can take from her.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Cohen's Blindsided will be profoundly moved by My Life, Deleted, a remarkable story of tragedy, hope, love, and perseverance.

    Then she was diagnosed with ALS, and her world turned upside down. I Remember Running is Darcy's story of change and loss and challenges during her first year with ALS, as she struggles to make sense of her diagnosis and redefine herself in the face of this terminal illness. With unflagging courage, wit, and eloquence, Darcy shares what she calls her "fast-forward" life, a life in which she applies for disability, leaves her job, and plans her own funeral as well as meets and moves in with her true love, buys a house, and gives birth to her first child in less time than it takes most of us to accomplish even one of these things. Beautifully written and wholly inspiring, I Remember Running proves that it is possible to live a rich, meaningful life after being diagnosed with a terminal illness, and will move readers to see the world in a different light.

    And in so doing, he offers something for everyone, no matter which strand draws you in.”—The New York Times Book ReviewIn November 2014, thirteen members of the Biden family gathered on Nantucket for Thanksgiving, a tradition they had been celebrating for the past forty years; it was the one constant in what had become a hectic, scrutinized, and overscheduled life. The Thanksgiving holiday was a much-needed respite, a time to connect, a time to reflect on what the year had brought, and what the future might hold. But this year felt different from all those that had come before. Joe and Jill Biden’s eldest son, Beau, had been diagnosed with a malignant brain tumor fifteen months earlier, and his survival was uncertain. “Promise me, Dad,” Beau had told his father. “Give me your word that no matter what happens, you’re going to be all right.” Joe Biden gave him his word.Promise Me Dad chronicles the year that followed, which would be the most momentous and challenging in Joe Biden’s extraordinary life and career. As vice president, Biden traveled more than a hundred thousand miles that year, across the world, dealing with crises in Ukraine, Central America, and Iraq. When a call came from New York, or Capitol Hill, or Kyiv, or Baghdad—“Joe, I need your help”—he responded. For twelve months, while Beau fought for and then lost his life, the vice president balanced the twin imperatives of living up to his responsibilities to his country and his responsibilities to his family. And never far away was the insistent and urgent question of whether he should seek the presidency in 2016.The year brought real triumph and accomplishment, and wrenching pain. But even in the worst times, Biden was able to lean on the strength of his long, deep bonds with his family, on his faith, and on his deepening friendship with the man in the Oval Office, Barack Obama.Writing with poignancy and immediacy, Joe Biden allows readers to feel the urgency of each moment, to experience the days when he felt unable to move forward as well as the days when he felt like he could not afford to stop.This is a book written not just by the president, but by a father, grandfather, friend, and husband. Promise Me Dad is a story of how family and friendships sustain us and how hope, purpose, and action can guide us through the pain of personal loss into the light of a new future.

    Forget about Letterman's Top Ten, Amy Krouse Rosenthal's random ponderings on quirky topics are refreshingly clever and zany. Her humor is of the great everyday observational type that everyone can relate to.

    Stunned to learn that her son, Sam, is about to become a father at nineteen, Lamott begins a journal about the first year of her grandson Jax's life. In careful and often hilarious detail, Lamott and Sam-about whom she first wrote so movingly in Operating Instructions-struggle to balance their changing roles with the demands of college and work, as they both forge new relationships with Jax's mother, who has her own ideas about how to raise a child. Lamott writes about the complex feelings that Jax fosters in her, recalling her own experiences with Sam when she was a single mother. Over the course of the year, the rhythms of life, death, family, and friends unfold in surprising and joyful ways. By turns poignant and funny, honest and touching, Some Assembly Required is the true story of how the birth of a baby changes a family-as this book will change everyone who reads it.

    As she faced life without the husband she called her “magic man,” Jai learned to make herself a priority to create a new life of hope and happiness—as she puts it, to “feel a spark of my own magic beginning to flicker.”     Dream New Dreams is a powerful story of grief, healing, and newfound independence. With advice artfully woven into an intimate, beautifully written narrative, Jai’s story will inspire not only the legions of readers who made The Last Lecture a bestseller, but also those who are embarking on a journey of loss and renewal themselves.

    I have loved and been loved. I have been given much and I have given something in return. Above all, I have been a sentient being, a thinking animal, on this beautiful planet, and that in itself has been an enormous privilege and adventure.” —Oliver SacksNo writer has succeeded in capturing the medical and human drama of illness as honestly and as eloquently as Oliver Sacks. During the last few months of his life, he wrote a set of essays in which he movingly explored his feelings about completing a life and coming to terms with his own death. “It is the fate of every human being,” Sacks writes, “to be a unique individual, to find his own path, to live his own life, to die his own death.”Together, these four essays form an ode to the uniqueness of each human being and to gratitude for the gift of life.

    Like twelve million other Americans, Sandra Beasley suffers from food allergies. Her allergies—severe and lifelong—include dairy, egg, soy, beef, shrimp, pine nuts, cucumbers, cantaloupe, honeydew, mango, macadamias, pistachios, cashews, swordfish, and mustard. Add to that mold, dust, grass and tree pollen, cigarette smoke, dogs, rabbits, horses, and wool, and it’s no wonder Sandra felt she had to live her life as “Allergy Girl.” When butter is deadly and eggs can make your throat swell shut, cupcakes and other treats of childhood are out of the question—and so Sandra’s mother used to warn guests against a toxic, frosting-tinged kiss with “Don’t kill the birthday girl!” It may seem that such a person is “not really designed to survive,” as one blunt nutritionist declared while visiting Sandra’s fourth-grade class. But Sandra has not only survived, she’s thrived—now an essayist, editor, and award-winning poet, she has learned to navigate a world in which danger can lurk in an unassuming corn chip. Don’t Kill the Birthday Girl is her story. With candor, wit, and a journalist’s curiosity, Sandra draws on her own experiences while covering the scientific, cultural, and sociological terrain of allergies. She explains exactly what an allergy is, describes surviving a family reunion in heart-of-Texas beef country with her vegetarian sister, delves into how being allergic has affected her romantic relationships, exposes the dark side of Benadryl, explains how parents can work with schools to protect their allergic children, and details how people with allergies should advocate for themselves in a restaurant. A compelling mix of memoir, cultural history, and science, Don’t Kill the Birthday Girl is mandatory reading for the millions of families navigating the world of allergies—and a not-to-be-missed literary treat for the rest of us.