Hacking Darwin: Genetic Engineering and the Future of Humanity


Jamie Metzl - 2019
    After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

The Meme Machine


Susan Blackmore - 1999
    The meme is also one of the most important--and controversial--concepts to emerge since 'The Origin of the Species' appeared nearly 150 years ago.In 'The Meme Machine' Susan Blackmore boldly asserts: "Just as the design of our bodies can be understood only in terms of natural selection, so the design of our minds can be understood only in terms of memetic selection." Indeed, Blackmore shows that once our distant ancestors acquired the crucial ability to imitate, a second kind of natural selection began, a survival of the fittest amongst competing ideas and behaviors. Ideas and behaviors that proved most adaptive - making tools, for example, or using language--survived and flourished, replicating themselves in as many minds as possible. These memes then passed themselves on from generation to generation by helping to ensure that the genes of those who acquired them also survived and reproduced. Applying this theory to many aspects of human life, Blackmore offers brilliant explanations for why we live in cities, why we talk so much, why we can't stop thinking, why we behave altruistically, how we choose our mates, and much more.With controversial implications for our religious beliefs, our free will, our very sense of "self," 'The Meme Machine' offers a provocative theory everyone will soon be talking about.

Homo Deus: A History of Tomorrow


Yuval Noah Harari - 2015
    This may seem hard to accept, but, as Harari explains in his trademark style—thorough, yet riveting—famine, plague and war have been transformed from incomprehensible and uncontrollable forces of nature into manageable challenges. For the first time ever, more people die from eating too much than from eating too little; more people die from old age than from infectious diseases; and more people commit suicide than are killed by soldiers, terrorists and criminals put together. The average American is a thousand times more likely to die from binging at McDonalds than from being blown up by Al Qaeda.What then will replace famine, plague, and war at the top of the human agenda? As the self-made gods of planet earth, what destinies will we set ourselves, and which quests will we undertake? Homo Deus explores the projects, dreams and nightmares that will shape the twenty-first century—from overcoming death to creating artificial life. It asks the fundamental questions: Where do we go from here? And how will we protect this fragile world from our own destructive powers? This is the next stage of evolution. This is Homo Deus.With the same insight and clarity that made Sapiens an international hit and a New York Times bestseller, Harari maps out our future.

Human Errors: A Panorama of Our Glitches, from Pointless Bones to Broken Genes


Nathan H. Lents - 2018
    But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

The Story of the Human Body: Evolution, Health, and Disease


Daniel E. Lieberman - 2013
    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

The Tangled Tree: A Radical New History of Life


David Quammen - 2018
    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

The Gap: The Science of What Separates Us from Other Animals


Thomas Suddendorf - 2013
    Our minds have spawned civilizations and technologies that have changed the face of the Earth, whereas even our closest animal relatives sit unobtrusively in their dwindling habitats. Yet despite longstanding debates, the nature of this apparent gap has remained unclear. What exactly is the difference between our minds and theirs? In The Gap, psychologist Thomas Suddendorf provides a definitive account of the mental qualities that separate humans from other animals, as well as how these differences arose. Drawing on two decades of research on apes, children, and human evolution, he surveys the abilities most often cited as uniquely human -- language, intelligence, morality, culture, theory of mind, and mental time travel -- and finds that two traits account for most of the ways in which our minds appear so distinct: Namely, our open-ended ability to imagine and reflect on scenarios, and our insatiable drive to link our minds together. These two traits explain how our species was able to amplify qualities that we inherited in parallel with our animal counterparts; transforming animal communication into language, memory into mental time travel, sociality into mind reading, problem solving into abstract reasoning, traditions into culture, and empathy into morality. Suddendorf concludes with the provocative suggestion that our unrivalled status may be our own creation -- and that the gap is growing wider not so much because we are becoming smarter but because we are killing off our closest intelligent animal relatives. Weaving together the latest findings in animal behavior, child development, anthropology, psychology, and neuroscience, this book will change the way we think about our place in nature. A major argument for reconsidering what makes us human, The Gap is essential reading for anyone interested in our evolutionary origins and our relationship with the rest of the animal kingdom.

How to Argue With a Racist: What Our Genes Do (and Don't) Say About Human Difference


Adam Rutherford - 2020
    But its toxic effects on society are plain to see—feeding white nationalism, fueling hatred, endangering lives, and corroding our discourse on everything from sports to intelligence. Even well-intentioned people repeat stereotypes based on “science,” because cutting-edge genetics are hard to grasp—and all too easy to distort. Paradoxically, these misconceptions are multiplying even as scientists make unprecedented discoveries in human genetics—findings that, when accurately understood, are powerful evidence against racism. We’ve never had clearer answers about who we are and where we come from, but this knowledge is sorely needed in our casual conversations about race.How to Argue With a Racist emphatically dismantles outdated notions of race by illuminating what modern genetics actually can and can’t tell us about human difference. We now know that the racial categories still dividing us do not align with observable genetic differences. In fact, our differences are so minute that, most of all, they serve as evidence of our shared humanity.

Y: The Descent of Men


Steve Jones - 2002
    With effervescent wit, Jones argues that men, biologically speaking, are the true second sex. Here he lays out the cases for and against masculinity -- exploring every biological aspect from the genesis of the Y chromosome onward -- based on the recent explosion of biological research. Along the way, he offers pithy commentary on topics such as male hormones, hair loss, and the hydraulics of man's most intimate organ. Fascinating and often surprising, Jones's evidence offers fresh fuel for the battle of the sexes.

She Has Her Mother's Laugh: The Powers, Perversions, and Potential of Heredity


Carl Zimmer - 2018
    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

Superior: The Return of Race Science


Angela Saini - 2019
    After the horrors of the Nazi regime in WWII, the mainstream scientific world turned its back on eugenics and the study of racial difference. But a worldwide network of eugenicists founded journals and funded research, providing the kind of shoddy studies that were ultimately cited in Richard Hernstein's and Charles Murray's 1994 title, The Bell Curve, which purported to show differences in intelligence among races.Whether you think of racist science as bad science, evil science, alt-right science, or pseudoscience, why would any contemporary scientist imagine that gross inequality is a fact of nature, rather than of political history? Angela Saini's Superior connects the dots, laying bare the history, continuity, and connections of modern racist science, some more subtle than you might think.

A Short History of Nearly Everything


Bill Bryson - 2003
    Taking as territory everything from the Big Bang to the rise of civilization, Bryson seeks to understand how we got from there being nothing at all to there being us. To that end, he has attached himself to a host of the world’s most advanced (and often obsessed) archaeologists, anthropologists, and mathematicians, travelling to their offices, laboratories, and field camps. He has read (or tried to read) their books, pestered them with questions, apprenticed himself to their powerful minds. A Short History of Nearly Everything is the record of this quest, and it is a sometimes profound, sometimes funny, and always supremely clear and entertaining adventure in the realms of human knowledge, as only Bill Bryson can render it. Science has never been more involving or entertaining.

Life Ascending: The Ten Great Inventions of Evolution


Nick Lane - 2009
    Comparing gene sequences, examining atomic structures of proteins, and looking into the geochemistry of rocks have helped explain evolution in more detail than ever before. Nick Lane expertly reconstructs the history of life by describing the ten greatest inventions of evolution (including DNA, photosynthesis, sex, and sight), based on their historical impact, role in organisms today, and relevance to current controversies. Who would have guessed that eyes started off as light-sensitive spots used to calibrate photosynthesis in algae? Or that DNA’s building blocks form spontaneously in hydrothermal vents? Lane gives a gripping, lucid account of nature’s ingenuity, and the result is a work of essential reading for anyone who has ever pondered or questioned the science underlying evolution’s greatest gifts to man.

Blueprint: The Evolutionary Origins of a Good Society


Nicholas A. Christakis - 2019
    But natural selection has given us a suite of beneficial social features, including our capacity for love, friendship, cooperation, and learning. Beneath all of our inventions -- our tools, farms, machines, cities, nations -- we carry with us innate proclivities to make a good society.In Blueprint, Nicholas A. Christakis introduces the compelling idea that our genes affect not only our bodies and behaviors, but also the ways in which we make societies, ones that are surprisingly similar worldwide.With many vivid examples -- including diverse historical and contemporary cultures, communities formed in the wake of shipwrecks, commune dwellers seeking utopia, online groups thrown together by design or involving artificially intelligent bots, and even the tender and complex social arrangements of elephants and dolphins that so resemble our own -- Christakis shows that, despite a human history replete with violence, we cannot escape our social blueprint for goodness.In a world of increasing political and economic polarization, it's tempting to ignore the positive role of our evolutionary past. But by exploring the ancient roots of goodness in civilization, Blueprint shows that our genes have shaped societies for our welfare and that, in a feedback loop stretching back many thousands of years, societies are still shaping our genes today.

Darwin's Dangerous Idea: Evolution and the Meanings of Life


Daniel C. Dennett - 1995
    Dennett, whom Chet Raymo of The Boston Globe calls "one of the most provocative thinkers on the planet," focuses his unerringly logical mind on the theory of natural selection, showing how Darwin's great idea transforms and illuminates our traditional view of humanity's place in the universe. Dennett vividly describes the theory itself and then extends Darwin's vision with impeccable arguments to their often surprising conclusions, challenging the views of some of the most famous scientists of our day.