Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    It promised to shed light on the deep mysteries of consciousness, as well as offer relief to addicts and the mentally ill. But in the 1960s, with the vicious backlash against the counter-culture, all further research was banned. In recent years, however, work has quietly begun again on the amazing potential of LSD, psilocybin and DMT. Could these drugs in fact improve the lives of many people? Diving deep into this extraordinary world and putting himself forward as a guinea-pig, Michael Pollan has written a remarkable history of psychedelics and a compelling portrait of the new generation of scientists fascinated by the implications of these drugs. How to Change Your Mind is a report from what could very well be the future of human consciousness.

    Prohibition’s end has led to a technological revolution that’s generated powerful medicines and products containing almost zero carcinogens and little smoke. Marijuana icon Ed Rosenthal and leading cannabis reporter David Downs guide readers through the best new consumer products, and demonstrate how to make and use the safest, cleanest extracts. Beyond Buds details how award-winning artisans make hash and concentrates, and includes modern techniques utilizing dry ice and CO2. The book is a primer on making kief, water hash, tinctures, topicals, edibles, and other extracts from cannabis leaves, trim, and bud bits, and it goes on to explore and simplify the more exotic and trendy marijuana-infused products, such as butane hash oil (BHO), shatter, wax, and budder. More complex than lighting a joint, these innovative products call for new accessories — special pipes, dabbing tools, and vaporizers — all of which are reviewed and pictured in the book. Beyond Buds expands on Rosenthal’s previous book Ask Ed: Marijuana Gold: Trash to Stash. Completely updated with full-color photographs that are both “how-to” guides and eye candy, this book enables not only the health-conscious toker but also the bottom line–driven cultivator.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    Weed. Grass. Mary Jane. We all think we know what cannabis is and what we use it for. But do we? Our collective understanding of this surprising plant has been muddled by politics and morality; what we think we know isn’t the real story.A war on cannabis has been waged in the United States since the early years of the twentieth century, yet in the past decade, society has undergone a massive shift in perspective that has allowed us to reconsider our beliefs. In Brave New Weed, Joe Dolce travels the globe to "tear down the cannabis closet" and de-mystify this new frontier, seeking answers to the questions we didn’t know we should ask.Dolce heads to a host of places, including Amsterdam, Israel, California, and Colorado, where he skillfully unfolds the odd, shocking, and wildly funny history of this complex plant. From the outlandish stories of murder trials where defendants claimed "insanity due to marijuana consumption" to the groundbreaking success stories about the plant’s impressive medicinal benefits, Dolce paints a fresh and much-needed portrait of cannabis, our changing attitudes toward it, and the brave new direction science and cultural acceptance are leading us.Enlightening, entertaining, and thought-provoking, Brave New Weed is a compelling read that will surprise and educate proponents on both sides of the cannabis debate.

    We spend 90 percent of our time inside, shuttling between homes and offices, schools and stores, restaurants and gyms. And yet, in many ways, the indoor world remains unexplored territory. For all the time we spend inside buildings, we rarely stop to consider: How do these spaces affect our mental and physical well-being? Our thoughts, feelings, and behaviors? Our productivity, performance, and relationships?In this wide-ranging, character-driven book, science journalist Emily Anthes takes us on an adventure into the buildings in which we spend our days, exploring the profound, and sometimes unexpected, ways that they shape our lives. Drawing on cutting-edge research, she probes the pain-killing power of a well-placed window and examines how the right office layout can expand our social networks. She investigates how room temperature regulates our cognitive performance, how the microbes hiding in our homes influence our immune systems, and how cafeteria design affects what—and how much—we eat.Along the way, Anthes takes readers into an operating room designed to minimize medical errors, a school designed to boost students’ physical fitness, and a prison designed to support inmates’ psychological needs. And she previews the homes of the future, from the high-tech houses that could monitor our health to the 3D-printed structures that might allow us to live on the Moon.The Great Indoors provides a fresh perspective on our most familiar surroundings and a new understanding of the power of architecture and design. It's an argument for thoughtful interventions into the built environment and a story about how to build a better world—one room at a time.

    Throughout our life, we look for ways to keep our mind sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age. Keep Sharp debunks common myths about aging and cognitive decline, explores whether there’s a “best” diet or exercise regimen for the brain, and explains whether it’s healthier to play video games that test memory and processing speed, or to engage in more social interaction. Discover what we can learn from “super-brained” people who are in their eighties and nineties with no signs of slowing down—and whether there are truly any benefits to drugs, supplements, and vitamins. Dr. Gupta also addresses brain disease, particularly Alzheimer’s, answers all your questions about the signs and symptoms, and shows how to ward against it and stay healthy while caring for a partner in cognitive decline. He likewise provides you with a personalized twelve-week program featuring practical strategies to strengthen your brain every day. Keep Sharp is the only owner’s manual you’ll need to keep your brain young and healthy regardless of your age!

    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    Introverts gain energy and power through reflection and solitude. Our culture, however, is geared toward the extrovert. The pressure to enjoy parties, chatter, and interactions can lead people to think that an inward orientation is a problem instead of an opportunity. Helgoe shows that the exact opposite is true: Introverts can capitalize on this inner source of power. INTROVERT POWER is a groundbreaking call for an introvert renaissance, a blueprint for how introverts can take full advantage of this hidden strength in daily life. Supplemented by the voices of several introverts, Helgoe presents a startling look at introvert numbers, influence, and economic might. Revolutionary and invaluable, INTROVERT POWER includes ideas for how introverts can learn to: Claim private spaceCarve out time to thinkBring a slower tempo into daily lifeCreate breaks in conversation and relationshipsDeal effectively with parties, interruptions, and crowds QUIET IS MIGHT. SOLITUDE IS STRENGTH. INTROVERSION IS POWER.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    From the world’s most painful hornet, to the flies that transmit deadly diseases, to millipedes that stop traffic, to the “bookworms” that devour libraries, to the Japanese beetles munching on your roses, Wicked Bugs delves into the extraordinary powers of many-legged creatures. With wit, style, and exacting research, Stewart has uncovered the most terrifying and titillating stories of bugs gone wild. It’s an A to Z of insect enemies, interspersed with sections that explore bugs with kinky sex lives (“She’s Just Not That Into You”), creatures lurking in the cupboard (“Fear No Weevil”), insects eating your tomatoes (“Gardener’s Dirty Dozen”), and phobias that feed our (sometimes) irrational responses to bugs (“Have No Fear”). Intricate and strangely beautiful etchings and drawings by Briony Morrow-Cribbs capture diabolical bugs of all shapes and sizes in this mixture of history, science, murder, and intrigue that begins—but doesn’t end—in your own backyard.

    Much more commonly, they are linked to sensory deprivation, intoxication, illness, or injury. People with migraines may see shimmering arcs of light or tiny, Lilliputian figures of animals and people. People with failing eyesight, paradoxically, may become immersed in a hallucinatory visual world. Hallucinations can be brought on by a simple fever or even the act of waking or falling asleep, when people have visions ranging from luminous blobs of color to beautifully detailed faces or terrifying ogres. Those who are bereaved may receive comforting “visits” from the departed. In some conditions, hallucinations can lead to religious epiphanies or even the feeling of leaving one’s own body. Humans have always sought such life-changing visions, and for thousands of years have used hallucinogenic compounds to achieve them. As a young doctor in California in the 1960s, Oliver Sacks had both a personal and a professional interest in psychedelics. These, along with his early migraine experiences, launched a lifelong investigation into the varieties of hallucinatory experience. Here, with his usual elegance, curiosity, and compassion, Dr. Sacks weaves together stories of his patients and of his own mind-altering experiences to illuminate what hallucinations tell us about the organization and structure of our brains, how they have influenced every culture’s folklore and art, and why the potential for hallucination is present in us all, a vital part of the human condition.

    Presented in an eye-popping package and filled with hyperdetailed photography of individual buds, this essential guide to marijuana is smart, practical, and exceedingly beautiful. The "Primer" section explores the culture of this complex flower and explains the botany that makes each strain unique. The "Buds" section describes the variations of lineage, flavor, and mental or physical high that define 170 exceptional strains. Poised to become the go-to marijuana guide for recreational and medicinal users alike, Green is easy to pick up and impossible to put down.

    Prepare. Trip. Transform!With so much misinformation surrounding magic mushrooms out there, it can be hard to separate fact from fiction. This is where Your Psilocybin Mushroom Companion comes in to help. In this book, you’ll find a comprehensive yet friendly guide to everything there is to know about magic mushrooms.Learn how to plan safe, effective trips with easy-to-follow step-by-step advice. Discover how to train a guide to take care of those on psychedelic voyages, as well as how to access the transformative nature of these experiences. Even learn how microdosing can improve your mood, cognitive functioning, creativity, physical stamina, and more.With the most up-to-date research, Your Psilocybin Mushroom Companion will put magic mushrooms into perspective, dispel myths and urban legends, and open your mind to the benefits of psychedelic tripping.

    It has been revised in such a way to retain Dr Comfort's original, revelatory advice while making it appropriate for the 21st century.