Each case includes an extended discussion, definition of terms, clinical pearls, and USMLE format review questions. This interactive learning system helps you understand essential concepts instead of memorizing facts.

    In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.

    That was, of course, an oblique reference to the mind-bending drugs that clouded perception--yet time has proven an equally effective hallucinogen. This book revisits the Sixties we forgot or somehow failed to witness. In a kaleidoscopic global tour of the decade, Gerard DeGroot reminds us that the Ballad of the Green Beret outsold Give Peace a Chance, that the Students for a Democratic Society were outnumbered by Young Americans for Freedom, that revolution was always a pipe dream, and that the Sixties belong to Reagan and de Gaulle more than to Kennedy and Dubcek. The Sixties Unplugged shows how opportunity was squandered, and why nostalgia for the decade has obscured sordidness and futility. DeGroot returns us to a time in which idealism, tolerance, and creativity gave way to cynicism, chauvinism, and materialism. He presents the Sixties as a drama acted out on stages around the world, a theater of the absurd in which China's Cultural Revolution proved to be the worst atrocity of the twentieth century, the Six-Day War a disaster for every nation in the Middle East, and a million slaughtered Indonesians martyrs to greed. The Sixties Unplugged restores to an era the prevalent disorder and inconvenient truths that longing, wistfulness, and distance have obscured. In an impressionistic journey through a tumultuous decade, DeGroot offers an object lesson in the distortions nostalgia can create as it strives to impose order on memory and value on mayhem.

    Gases and dust particles ejected into the atmosphere changed weather patterns around the world, resulting in the infamous ''year without a summer'' in North America, food riots in Europe, and a widespread cholera epidemic. And the gloomy weather inspired Mary Shelley to write the gothic novel Frankenstein.This book tells the story of nine such epic volcanic events, explaining the related geology for the general reader and exploring the myriad ways in which the earth's volcanism has affected human history. Zeilinga de Boer and Sanders describe in depth how volcanic activity has had long-lasting effects on societies, cultures, and the environment. After introducing the origins and mechanisms of volcanism, the authors draw on ancient as well as modern accounts--from folklore to poetry and from philosophy to literature. Beginning with the Bronze Age eruption that caused the demise of Minoan Crete, the book tells the human and geological stories of eruptions of such volcanoes as Vesuvius, Krakatau, Mount Pel�e, and Tristan da Cunha. Along the way, it shows how volcanism shaped religion in Hawaii, permeated Icelandic mythology and literature, caused widespread population migrations, and spurred scientific discovery.From the prodigious eruption of Thera more than 3,600 years ago to the relative burp of Mount St. Helens in 1980, the results of volcanism attest to the enduring connections between geology and human destiny.

    Many have survived because of an author’s status—part of the reason we have so much of Chaucer’s writing, for example, is because he was a London-based government official first and a poet second. Other works by the less influential have narrowly avoided ruin, like the book of illiterate Margery Kempe, found in a country house closet, the cover nibbled on by mice. Scholar Mary Wellesley recounts the amazing origins of these remarkable manuscripts, surfacing the important roles played by women and ordinary people—the grinders, binders, and scribes—in their creation and survival.  The Gilded Page is the story of the written word in the manuscript age. Rich and surprising, The Gilded Page shows how the most exquisite objects ever made by human hands came from unexpected places.

    But while this medieval medicine now seems archaic, it also made a critical contribution to modern science.Medieval Bodies guides us on a head-to-heel journey through this era’s revolutionary advancements and disturbing convictions. We learn about the surgeons who dissected a living man’s stomach, then sewed him up again; about the geographers who delineated racial groups by skin color; and about the practice of fasting to gain spiritual renown. Encompassing medicine and mysticism, politics and art—and complete with vivid, full-color illustrations—Medieval Bodies shows us how it felt to live and die a thousand years ago.

    Medieval dentists burned candles in patients' mouths to kill invisible worms gnawing at their teeth. Renaissance physicians, by law, timed surgical procedures with the position of the stars, and instructed epileptics to collect fresh blood from the newly beheaded. Highlighting bad science, oafish behavior, and stomach-turning procedures that hurt more than helped, Strange Medicine presents extraordinary but true facts and an honor roll of doctors, scientists, and dreamers who gave a whole new meaning to clinical trials!

    Its very name evokes images of almost superhuman courage, endurance, and fighting spirit. But until now, the story of what happened at Marathon has been told exclusively through the narrow viewpoint of specialists in antiquity. In this eye-opening new book, acclaimed journalist Jim Lacey, both a military historian and a combat veteran, takes a fresh look at Marathon and reveals why the battle happened, how it was fought, and whether, in fact, it saved Western civilization.Lacey brilliantly reconstructs the world of the fifth century B.C. leading up to the astonishing military defeat of the Persian Empire by the vastly undermanned but determined Greek defenders. Using the seminal work of Herodotus as his starting point, Lacey reconstructs the tactical and strategic scenario of the battle, including how many combatants each side might have used and who actually led the Greeks. He also disputes the long-repeated myths of Athenian inexperience and effete Persian arrogance.With the kind of vivid detail that characterizes the best modern war reportage, Lacey shows how the heavily armed Persian army was shocked, demoralized, and ultimately defeated by the relentless assault of the Athenian phalanx, which battered the Persian line in a series of brutal attacks. He reveals the fascinating aftermath of Marathon, how its fighters became the equivalent of our “Greatest Generation,” and challenges the view of many historians that Marathon ultimately proved the Greek “Western way of war” to be the superior strategy for fighting—and winning—battles to the present day. Immediate, visceral, and full of new analyses that defy decades of conventional wisdom, The First Clash is a superb interpretation of a conflict that indeed made the world safe for Aristotle, Plato, and our own modern democracy. But it was also a battle whose legacy and lessons have often been misunderstood—perhaps, now more than ever, at our own peril.

    Now, with the discovery of Richard III's bones under a parking lot in Leicester, England, interest in this divisive and enigmatic figure in British history is at an all-time high. It is a compelling story to scholars as well as general readers, who continue to seek out the kind of strong narrative history that David Horspool delivers in this groundbreaking biography of the king.Richard III dispassionately examines the legend as well as the man to uncover both what we know of the life of Richard, and the way that his reputation has been formed and re-formed over centuries. But beyond simply his reputation, there is no dispute that the last Plantagenet is a pivotal figure in English history--his death signaled the end of the War of the Roses, and, arguably, the end of the medieval period in England--and Horspool's biography chronicles this tumultuous time with flair.This narrative-driven and insightful biography lays out a view of Richard that is fair to his historical character and to his background in the medieval world. Above all, it is authoritative in its assessment of a king who came to the throne under extraordinary circumstances.

    Encompassing a grand sweep of human history, A History of the World in 100 Objects begins with one of the earliest surviving objects made by human hands, a chopping tool from the Olduvai gorge in Africa, and ends with objects which characterise the world we live in today. Seen through MacGregor's eyes, history is a kaleidoscope - shifting, interconnected, constantly surprising, and shaping our world today in ways that most of us have never imagined. A stone pillar tells us about a great Indian emperor preaching tolerance to his people; Spanish pieces of eight tell us about the beginning of a global currency; and an early Victorian tea-set speaks to us about the impact of empire. An intellectual and visual feast, this is one of the most engrossing and unusual history books published in years. 'Brilliant, engagingly written, deeply researched' Mary Beard, Guardian 'A triumph: hugely popular, and rightly lauded as one of the most effective and intellectually ambitious initiatives in the making of 'public history' for many decades' Sunday Telegraph 'Highly intelligent, delightfully written and utterly absorbing ' Timothy Clifford, Spectator 'This is a story book, vivid and witty, shining with insights, connections, shocks and delights' Gillian Reynolds Daily Telegraph

    In The Woman with a Worm in Her Head, Dr. Pamela Nagami reveals-through real-life cases-the sobering facts about some of the world's most horrific diseases: the warning signs, the consequences, treatments, and most compellingly, what it feels like to make medical and ethical decisions that can mean the difference between life and death.Unfailingly precise, calmly instructive, and absolutely engrossing, The Woman with the Worm in Her Head offers both useful information and enjoyable reading.

    The first Indian Army officer to be promoted to the five-star rank of Field Marshal, Sam Bahadur continues to be the most admired of our Army Chiefs.

    A startling and precocious example of her celebrated wit—not to mention a brilliant social commentary—this lively piece sweeps rapidly across almost four centuries of British monarchy. In rambunctious and wickedly funny prose, Austen's critique spans from Henry IV to Charles I, from Richard III to Mary Queen of Scots, offering a fierce parody of the kind of biased history that young ladies of Austen's time were being forced to study. Reproduced here in its entirety, this is a rare, tantalizing look at the great novelist's budding talent, and an extraordinary bit of literary history that lay unpublished for more than 130 years.Charles Dickens's A Child's History of England, by contrast, was written and published at the height of its author's considerable fame. A gory and dramatic account, full of villains and heroes, the essay was originally intended as a study-piece for his children, but in fact represented a sly, unconventional countertext to the more straitlaced historical canon. Dickens's exciting, flamboyant narrative is hugely evocative, both of the history he describes and of the time in which he himself was writing.With an insightful introduction by bestselling historian David Starkey, Two Histories of England brings together, in a single, irresistible volume, these remarkable—and remarkably overlooked—literary treasures by two of the world's most beloved writers.

    The greatest historians are vivid storytellers, Robert Lacey reminds us, and in Great Tales from English History, he proves his place among them, illuminating in unforgettable detail the characters and events that shaped a nation. In this volume, Lacey limns the most important period in England's past, highlighting the spread of the English language, the rejection of both a religion and a traditional view of kingly authority, and an unstoppable movement toward intellectual and political freedom from 1387 to 1689. Opening with Chaucer's Canterbury Tales and culminating in William and Mary's "Glorious Revolution," Lacey revisits some of the truly classic stories of English history: the Battle of Agincourt, where Henry V's skilled archers defeated a French army three times as large; the tragic tale of the two young princes locked in the Tower of London (and almost certainly murdered) by their usurping uncle, Richard III; Henry VIII's schismatic divorce, not just from his wife but from the authority of the Catholic Church; "Bloody Mary" and the burning of religious dissidents; Sir Francis Drake's dramatic, if questionable, part in the defeat of the Spanish Armada; and the terrible and transformative Great Fire of London, to name but a few. Here Anglophiles will find their favorite English kings and queens, villains and victims, authors and architects - from Richard II to Anne Boleyn, the Virgin Queen to Oliver Cromwell, Samuel Pepys to Christopher Wren, and many more. Continuing the "eminently readable, highly enjoyable" (St. Louis Post-Dispatch) history he began in volume I of Great Tales from English History, Robert Lacey has drawn on the most up-to-date research to present a taut and riveting narrative, breathing life into the most pivotal characters and exciting landmarks in England's history.

    Bronowski's exciting, illustrated investigation offers a perspective not just on science, but on civilization itself. Lower than the angelsForewordThe harvest of the seasons The grain in the stoneThe hidden structure The music of the spheresThe starry messanger The majestic clockworkThe drive for power The ladder of creation World within world Knowledge or certainty Generation upon generationThe long childhoodBibliographyIndex