We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise.So we've all heard of genes, but how do they actually work?According to legend, Ernest Hemingway was once given a six-toed cat by an old sea captain, and her distinctive descendants still roam the writer's Florida estate today. Scientists now know that the fault driving this profusion of digits lies in a tiny genetic control switch, miles away (in molecular terms) from the gene that 'makes' toes. And it's the same mistake that gives rise to multi-toed humans too.There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. And figuring out how it all works – how your genes make you, you – is a major challenge for researchers around the world.Drawing on stories ranging from six-toed cats and stickleback hips to wobbly worms and zombie genes, geneticist Kat Arney explores the how our genes work, creating a companion reader to the book of life itself.

    New stadiums in this completely revised and updated edition include Citizens Bank Ballpark (Philadelphia), PETCO Park (San Diego), and the newly renovated RFK Stadium (Washington, D.C.) home to the Washington Nationals. Crammed with the statistics baseball fans love, Take Me Out to the Ballpark will hit a home run with legions of new readers this fall.

    Weight gain and obesity are driven by hormones—in everyone—and only by understanding the effects of insulin and insulin resistance can we achieve lasting weight loss.In this highly readable and provocative book, Dr. Jason Fung sets out an original, robust theory of obesity that provides startling insights into proper nutrition. In addition to his five basic steps, a set of lifelong habits that will improve your health and control your insulin levels, Dr. Fung explains how to use intermittent fasting to break the cycle of insulin resistance and reach a healthy weight—for good.

    This clear, concise look at the basic principles and concepts of genetics uses a human genetics perspective to discuss the methods and experiments upon which genetic principles are based, such as DNA replication.

    Wes Burgess, the diagnosis of bipolar disorder means hope-hope for the estimated ten million people who will develop the disorder during their lifetimes, and hope for the families and friends of people who suffer from it. Drawing upon the real questions asked by patients and families during his nearly twenty years as a bipolar specialist, The Bipolar Handbook comprehensively tackles every area of the disorder, from its causes to medical treatment and psychotherapy, to strategies for creating a healthy lifestyle, to the prevention of, coping with, and treatment of bipolar episodes. From the more than five hundred questions and answers, you'll learn: - what to expect when pursuing a diagnosis- how to choose the right doctor or specialist- how to get the disorder under control- what treatments and medication protocols are best for you- how to reduce stress to prevent manic and depressive episodes- what family members and friends can do to support you, and more Dr. Burgess also addresses unique lifestyle concerns facing bipolar individuals. Special chapters on practical strategies for career success, building healthy relationships, issues that specifically affect bipolar women, and coping techniques for families and friends further explore the impact of the disorder on daily life. The Bipolar Handbook's easy-to-access format and full chapter of resources, as well as diagnostic criteria from the American Psychiatric Association and the National Institute for Mental Health, make this a versatile guide-perfect for quick reference and in-depth discovery.

    It uses a taxonomic approach for the study of pathogens.

    What happened, how it happened, and what it means to you today. A colorful cast of characters whose discoveries were often driven not only by personal tragedy, curiosity, and hard work, but petty bickering, dumb luck, and a healthy dose of humor. For anyone interested in science, medicine, and beyond... Why are you alive right now? Chances are, you owe your life to one of the remarkable medical discoveries in this book. Maybe it was vaccines. Or antibiotics. Or X-rays. Revolutionary medical breakthroughs like these haven’t just changed the way we treat disease, they’ve transformed how we understand ourselves and the world we live in. In Breakthrough!, Jon Queijo tells the hidden stories behind 10 of history’s most amazing medical discoveries. This isn’t dry history: These are life-and-death mysteries uncovered, tales of passionate, often-mocked individuals who stood their ground and were proven right. From germs to genetics, the ancient Hippocrates to the cutting edge, these are stories that have changed the world—and, quite likely, saved your life.

    Integrated central case studies woven throughout each chapter, use real-life stories to give you a tangible and engaging framework around which to learn and understand the science behind environmental issues. Printed on FSC (Forest Stewardship Council) certified paper, the newly revised Fourth Edition engages you through the addition of new EnvisionIt photo essays.

    One of the biggest fears of fasting is the fear hunger, the false hunger that most people are afraid of while depleting their glycogen stores (the body sugar storage). Fasting has often been associated with religious customs. It is time to define a line between the two. In Periodic Fasting, I embark on a timeless journey from the very beginning of life on Earth, through early human societies, through the middle Ages and into modern days to explore the concepts and practices of prolonged fasting and intermittent fasting (IF). Periodic Fasting is about: 1. My early life encounters with fasting in the small village of my grandparents (using a high-carb diet). 2. How primitive life-forms on Earth and fasting co-evolved; fasting in the animal kingdom. 3. Early hominid species, food restriction, and meal frequency. The first organized human societies and the switch between irregular feeding to regular dietary patterns. Circadian rhythmicity and meal timing. 4. The personal story of a man from the middle Ages who started consuming less food in his mid-thirties because of poor health and lived to 102 years (narrated by himself). 5. The dozens of prolonged fasting experiments in the beginning of the 20th century; fasting as a cure to many ailments. 6. How people can live without food for 139, 236 and even 382 days (medically supervised experiments). Details of 7-40 days fasts done by lean people for rejuvenation, detoxification and increased life span. 7. The emerging science and the studies of fasting from the mid-20th century (pathological implications - diabetes, obesity, CVD, cancer, and others). 8. How fasting and semi-starvation can be totally opposite: disturbing stories from the Second World War. 9. The molecular mechanisms of fasting: what happens when your body focuses on cell repair and tissue rejuvenation, instead of digesting food. 10. How the secretion of some hormones may be widely misunderstood: especially thyroid hormones and insulin. On muscle-loss phobia, mainstream media, and bro-science. 11. The modern-day science of prolonged fasting and intermittent fasting (AMPk, SIRT, FOXO, etc). 12. My personal prolonged water-only fasting experiment; insights into refeeding and realimentation after long-term fasting. 13. My 1 year and 3 months daily intermittent fasting protocol (still on-going). My ever-adapting exercising protocol (lifting), what I eat everyday, what supplements I use and what other cool strategies help me stay consistent and compliant with the protocol. 14. How I combine intermittent fasting (IF), a well formulated ketogenic diet, and calorie restriction to immensely increase the quality of my life, and paradoxically, never feel hungry; how energy levels and mood can increase if you correctly adopt a fasting protocol. Once armed with this knowledge, you will drastically alter your perspective about your body's limits.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    Finding these forays both puzzling and exhilarating, Robb dug deeper into the science of dreams at an extremely opportune moment: just as researchers began to understand why dreams exist. They aren’t just random events; they have clear purposes. They help us learn and even overcome psychic trauma. Robb draws on fresh and forgotten research, as well as her experience and that of other dream experts, to show why dreams are vital to our emotional and physical health. She explains how we can remember our dreams better—and why we should. She traces the intricate links between dreaming and creativity, and even offers advice on how we can relish the intense adventure of lucid dreaming for ourselves.Why We Dream is a clear-eyed, cutting-edge examination of the meaning and purpose of our nightly visions and a guide to changing our dream lives—and making our waking lives richer, healthier, and happier.

    Oliver Sacks--called "the poet laureate of medicine" by the New York Times--illuminated the mysteries of the brain for a wide audience in a series of richly acclaimed books, including Awakenings and The Man Who Mistook His Wife for a Hat, and numerous The New Yorker articles. In this collection of interviews, Sacks is at his most candid and disarming, rich with insights about his life and work. Any reader of Oliver Sacks will find in this book an entirely new way of looking at a brilliant writer"--

    Research psychologist Sonja Lyubomirsky's pioneering concept of the 40% solution shows you how Drawing on her own groundbreaking research with thousands of men and women, research psychologist and University of California professor of psychology Sonja Lyubomirsky has pioneered a detailed yet easy-to-follow plan to increase happiness in our day-to-day lives-in the short term and over the long term. The How of Happiness is a different kind of happiness book, one that offers a comprehensive guide to understanding what happiness is, and isn't, and what can be done to bring us all closer to the happy life we envision for ourselves. Using more than a dozen uniquely formulated happiness-increasing strategies, The How of Happiness offers a new and potentially life- changing way to understand our innate potential for joy and happiness as well as our ability to sustain it in our lives. Beginning with a short diagnostic quiz that helps readers to first quantify and then to understand what she describes as their "happiness set point," Lyubomirsky reveals that this set point determines just 50 percent of happiness while a mere 10 percent can be attributed to differences in life circumstances or situations. This leaves a startling, and startlingly underdeveloped, 40 percent of our capacity for happiness within our power to change. Lyubomirsky's "happiness strategies" introduce readers to the concept of intentional activities, mindful actions that they can use to achieve a happier life. These include exercises in practicing optimism when imagining the future, instruction in how best to savor life's pleasures in the here and now, and a thoroughgoing explanation of the importance of staying active to being happy. Helping readers find the right fit between the goals they set and the activities she suggests, Lyubomirsky also helps readers understand the many obstacles to happiness as well as how to harness individual strengths to overcome them. Always emphasizing how much of our happiness is within our control, Lyubomirsky addresses the "scientific how" of her happiness research, demystifying the many myths that unnecessarily complicate its pursuit. Unlike those of many self-help books, all her recommendations are supported by scientific research. The How of Happiness is both a powerful contribution to the field of positive psychology and a gift to all those who have questioned their own well- being and sought to take their happiness into their own hands.

    He was eager to begin his first practice, but it turned out to be more than he bargained for. In just two years, in September, 1918, the entire village was sickened in rapid succession in the flu pandemic that killed quickly and indiscriminately throughout the world. It was wartime, and Nixon was unable to find help., This story is an up close and personal account of what it was like to be sick with the HINI type virus in 1918. It is a tale of a dedicated doctor whose selflessness, compassion and courage helped the villagers survive in the pandemic that killed more people in a year than the Black Death killed in a century...

    Illustrated.