The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    Since its creation in 2010, Instagram’s fun and simple interface has captured our collective imagination, swiftly becoming a way of life. In No Filter: The Inside Story of Instagram, technology reporter Sarah Frier explains how Instagram’s founders married art and technology to overcome skeptics and to hook the public on visual storytelling. At first, Instagram initially attracted artisans, but then the platform exploded in popularity among the masses, creating an entire industry of digital influencers that’s now worth tens of billions of dollars. Eighteen months after Instagram’s launch and explosive growth, the founders—Kevin Systrom and Mike Krieger—made the gut-wrenching decision to sell the company to Facebook. For most companies, that would be the end of the story; but for Instagram, it was only the beginning. Instagram borrowed some lessons from Facebook and rejected others, until eventually its success stirred tension with Facebook’s CEO Mark Zuckerberg, just as Facebook became embroiled in a string of public crises. Frier unearths the details that led to the cofounders’ departure, bringing to light dramatic moments unknown to the public until now. At its heart, No Filter draws on unprecedented exclusive access—from the founders of Instagram, as well as employees, executives, and competitors; hedge fund billionaire Ray Dalio; Anna Wintour of Vogue; Kris Jenner of the Kardashian-Jenner empire; and a plethora of influencers, from fashionistas with millions of followers to owners of famous dogs worldwide—to show how Instagram has fundamentally changed the way we communicate, shop, eat, and travel. The book brings readers inside users’ strategies to craft their personal image and fame, explaining how the company’s product decisions have affected the structure of our society. From teenagers to the pope, No Filter tells the captivating story of how Instagram not only created a new industry but also changed our lives.

    But they are under threat as never before, and their problems are spreading across the continent. The Death and Life of the Great Lakes is prize-winning reporter Dan Egan’s compulsively readable portrait of an ecological catastrophe happening right before our eyes, blending the epic story of the lakes with an examination of the perils they face and the ways we can restore and preserve them for generations to come.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    They were hunter-gatherers, consummate foraging experts, but taking the world as they found it. Then a revolution occurred – our ancestors’ interaction with other species changed. They began to tame them. The human population boomed; civilization began.In her new book, Tamed, Alice Roberts uncovers the amazing deep history of ten familiar species with incredible wild pasts: dogs, apples and wheat; cattle; potatoes and chickens; rice, maize, and horses – and, finally, humans. Alice Roberts not only reveals how becoming part of our world changed these animals and plants, but shows how they became our allies, essential to the survival and success of our own species – and to our future.Enlightening, wide-ranging and endlessly fascinating, Tamed is an epic story, encompassing hundreds of thousands of years of history and archaeology alongside cutting-edge genetics and anthropology. Yet it is also a deeply personal journey that will change how we see ourselves and the species on which we have left our mark.

    In Turing’s Cathedral, George Dyson focuses on a small group of men and women, led by John von Neumann at the Institute for Advanced Study in Princeton, New Jersey, who built one of the first computers to realize Alan Turing’s vision of a Universal Machine. Their work would break the distinction between numbers that mean things and numbers that do things—and our universe would never be the same. Using five kilobytes of memory (the amount allocated to displaying the cursor on a computer desktop of today), they achieved unprecedented success in both weather prediction and nuclear weapons design, while tackling, in their spare time, problems ranging from the evolution of viruses to the evolution of stars. Dyson’s account, both historic and prophetic, sheds important new light on how the digital universe exploded in the aftermath of World War II. The proliferation of both codes and machines was paralleled by two historic developments: the decoding of self-replicating sequences in biology and the invention of the hydrogen bomb. It’s no coincidence that the most destructive and the most constructive of human inventions appeared at exactly the same time.  How did code take over the world? In retracing how Alan Turing’s one-dimensional model became John von Neumann’s two-dimensional implementation, Turing’s Cathedral offers a series of provocative suggestions as to where the digital universe, now fully three-dimensional, may be heading next.

    The ice sheet that covers it is 700 miles wide and 1,500 miles long, and is composed of nearly three quadrillion tons of ice. For the last 150 years, explorers and scientists have sought to understand Greenland--at first hoping that it would serve as a gateway to the North Pole, and later coming to realize that it contained essential information about our climate. Locked within this vast and frozen white desert are some of the most profound secrets about our planet and its future. Greenland's ice doesn't just tell us where we've been. More urgently, it tells us where we're headed.In The Ice at the End of the World, Jon Gertner explains how Greenland has evolved from one of earth's last frontiers to its largest scientific laboratory. The history of Greenland's ice begins with the explorers who arrived here at the turn of the twentieth century--first on foot, then on skis, then on crude, motorized sleds--and embarked on grueling expeditions that took as long as a year and often ended in frostbitten tragedy. Their original goal was simple: to conquer Greenland's seemingly infinite interior. Yet their efforts eventually gave way to scientists who built lonely encampments out on the ice and began drilling--one mile, two miles down. Their aim was to pull up ice cores that could reveal the deepest mysteries of earth's past, going back hundreds of thousands of years.Today, scientists from all over the world are deploying every technological tool available to uncover the secrets of this frozen island before it's too late. As Greenland's ice melts and runs off into the sea, it not only threatens to affect hundreds of millions of people who live in coastal areas. It will also have drastic effects on ocean currents, weather systems, economies, and migration patterns.Gertner chronicles the unfathomable hardships, amazing discoveries, and scientific achievements of the Arctic's explorers and researchers with a transporting, deeply intelligent style--and a keen sense of what this work means for the rest of us. The melting ice sheet in Greenland is, in a way, an analog for time. It contains the past. It reflects the present. It can also tell us how much time we might have left.

    Now he broadens the warning: the entire human game, he suggests, has begun to play itself out.Bill McKibben’s groundbreaking book The End of Nature -- issued in dozens of languages and long regarded as a classic -- was the first book to alert us to global warming. But the danger is broader than that: even as climate change shrinks the space where our civilization can exist, new technologies like artificial intelligence and robotics threaten to bleach away the variety of human experience.Falter tells the story of these converging trends and of the ideological fervor that keeps us from bringing them under control. And then, drawing on McKibben’s experience in building 350.org, the first truly global citizens movement to combat climate change, it offers some possible ways out of the trap. We’re at a bleak moment in human history -- and we’ll either confront that bleakness or watch the civilization our forebears built slip away.Falter is a powerful and sobering call to arms, to save not only our planet but also our humanity.

    A young man is murdered for his prized pet fish. An Asian tycoon buys a single specimen for $150,000. Meanwhile, a pet detective chases smugglers through the streets of New York. Delving into an outlandish world of obsession, paranoia, and criminality, The Dragon Behind the Glass tells the story of a fish like none other. Treasured as a status symbol believed to bring good luck, the Asian arowana, or “dragon fish,” is a dramatic example of a modern paradox: the mass-produced endangered species. While hundreds of thousands are bred in captivity, the wild fish has become a near-mythical creature. From the South Bronx to Borneo and beyond, journalist Emily Voigt follows the trail of the arowana to learn its fate in nature. With a captivating blend of personal reporting, history, and science, Voigt traces our fascination with aquarium fish back to the era of exploration when intrepid naturalists stood on the cutting edge of modern science, discovering new species around the globe. In an age when freshwater fish now comprise one of the most rapidly vanishing groups of animals, she unearths a surprising truth behind the arowana’s rise to fame—one that calls into question how we protect the world’s rarest species. An elegant examination of the human conquest of nature, The Dragon Behind the Glass revels in the sheer wonder of life’s diversity and lays bare our deepest desire—to hold on to what is wild.

    But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    Both the book and film were inspired by a series of multimedia presentations on global warming that Gore created and delivers to groups around the world. With this book, Gore, who is one of our environmental heroes—and a leading expert—brings together leading-edge research from top scientists around the world; photographs, charts, and other illustrations; and personal anecdotes and observations to document the fast pace and wide scope of global warming. He presents, with alarming clarity and conclusiveness—and with humor, too—that the fact of global warming is not in question and that its consequences for the world we live in will be disastrous if left unchecked. This riveting new book—written in an accessible, entertaining style—will open the eyes of even the most skeptical.

    Delving into brand-new research, she uncovers the powers of the natural world to improve health, promote reflection and innovation, and strengthen our relationships. As our modern lives shift dramatically indoors, these ideas—and the answers they yield—are more urgent than ever.

    But we should--even those of us who take care of our business in pristine, sanitary conditions. For it's not only in developing countries that human waste is a major public health threat: population growth is taxing even the most advanced sewage systems, and the disease spread by waste kills more people worldwide every year than any other single cause of death. Even in America, 1.95 million people have no access to an indoor toilet. Yet the subject remains unmentionable."The Big Necessity "takes aim at the taboo, revealing everything that matters about how people do--and don't--deal with their own waste. Moving from the deep underground sewers of Paris, London, and New York--an infrastructure disaster waiting to happen--to an Indian slum where ten toilets are shared by 60,000 people, Rose George stops along the way to explore the potential saviors: China's five million biogas digesters, which produce energy from waste; the heroes of third world sanitation movements; the inventor of the humble Car Loo; and the U.S. Army's personal lasers used by soldiers to zap their feces in the field.With razor-sharp wit and crusading urgency, mixing levity with gravity, Rose George has turned the subject we like to avoid into a cause with the most serious of consequences.

    But, Alex Bellos says, "math can be inspiring and brilliantly creative. Mathematical thought is one of the great achievements of the human race, and arguably the foundation of all human progress. The world of mathematics is a remarkable place."Bellos has traveled all around the globe and has plunged into history to uncover fascinating stories of mathematical achievement, from the breakthroughs of Euclid, the greatest mathematician of all time, to the creations of the Zen master of origami, one of the hottest areas of mathematical work today. Taking us into the wilds of the Amazon, he tells the story of a tribe there who can count only to five and reports on the latest findings about the math instinct--including the revelation that ants can actually count how many steps they've taken. Journeying to the Bay of Bengal, he interviews a Hindu sage about the brilliant mathematical insights of the Buddha, while in Japan he visits the godfather of Sudoku and introduces the brainteasing delights of mathematical games.Exploring the mysteries of randomness, he explains why it is impossible for our iPods to truly randomly select songs. In probing the many intrigues of that most beloved of numbers, pi, he visits with two brothers so obsessed with the elusive number that they built a supercomputer in their Manhattan apartment to study it. Throughout, the journey is enhanced with a wealth of intriguing illustrations, such as of the clever puzzles known as tangrams and the crochet creation of an American math professor who suddenly realized one day that she could knit a representation of higher dimensional space that no one had been able to visualize. Whether writing about how algebra solved Swedish traffic problems, visiting the Mental Calculation World Cup to disclose the secrets of lightning calculation, or exploring the links between pineapples and beautiful teeth, Bellos is a wonderfully engaging guide who never fails to delight even as he edifies. "Here's Looking at Euclid "is a rare gem that brings the beauty of math to life.