Along the way, she meets biologists who are trying to preserve the world's rarest fish, which lives in a single tiny pool in the middle of the Mojave; engineers who are turning carbon emissions to stone in Iceland; Australian researchers who are trying to develop a super coral that can survive on a hotter globe; and physicists who are contemplating shooting tiny diamonds into the stratosphere to cool the earth.One way to look at human civilization, says Kolbert, is as a ten-thousand-year exercise in defying nature. In The Sixth Extinction, she explored the ways in which our capacity for destruction has reshaped the natural world. Now she examines how the very sorts of interventions that have imperiled our planet are increasingly seen as the only hope for its salvation.

    But which one? And how?Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they’ve never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. It could be Ebola, avian flu, a drug-resistant superbug, or something completely new. While we can’t know which pathogen will cause the next pandemic, by unraveling the story of how pathogens have caused pandemics in the past, we can make predictions about the future. In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, the prizewinning journalist Sonia Shah—whose book on malaria, The Fever, was called a “tour-de-force history” (The New York Times) and “revelatory” (The New Republic)—interweaves history, original reportage, and personal narrative to explore the origins of contagions, drawing parallels between cholera, one of history’s most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.To reveal how a new pandemic might develop, Sonia Shah tracks each stage of cholera’s dramatic journey, from its emergence in the South Asian hinterlands as a harmless microbe to its rapid dispersal across the nineteenth-century world, all the way to its latest beachhead in Haiti. Along the way she reports on the pathogens now following in cholera’s footsteps, from the MRSA bacterium that besieges her own family to the never-before-seen killers coming out of China’s wet markets, the surgical wards of New Delhi, and the suburban backyards of the East Coast.By delving into the convoluted science, strange politics, and checkered history of one of the world’s deadliest diseases, Pandemic reveals what the next global contagion might look like— and what we can do to prevent it.

    For real.If you're like most people, geometry is a sterile and dimly remembered exercise you gladly left behind in the dust of ninth grade, along with your braces and active romantic interest in pop singers. If you recall any of it, it's plodding through a series of miniscule steps only to prove some fact about triangles that was obvious to you in the first place. That's not geometry. Okay, it is geometry, but only a tiny part, which has as much to do with geometry in all its flush modern richness as conjugating a verb has to do with a great novel.Shape reveals the geometry underneath some of the most important scientific, political, and philosophical problems we face. Geometry asks: Where are things? Which things are near each other? How can you get from one thing to another thing? Those are important questions. The word "geometry," from the Greek for "measuring the world." If anything, that's an undersell. Geometry doesn't just measure the world—it explains it. Shape shows us how.

    In a spirited tour across continents and cultures, Adam Rogers takes us from bourbon country to the world’s top gene-sequencing labs, introducing us to the bars, barflies, and evolving science at the heart of boozy technology. He chases the physics, biology, chemistry, and metallurgy that produce alcohol, and the psychology and neurobiology that make us want it. If you’ve ever wondered how your drink arrived in your glass, or what it will do to you, Proof makes an unparalleled drinking companion.

    Perhaps ideas have us. After all, ideas do appear to have a life of their own. And it is they, not us, that benefit most when they are spread. Many biologists have already come to the opinion that our genes are selfish entities, tricking us into helping them to reproduce. Is it the same with our ideas?     Jonnie Hughes, a science writer and documentary filmmaker, investigates the evolution of ideas in order to find out. Adopting the role of a cultural Charles Darwin, Hughes heads off, with his brother in tow, across the Midwest to observe firsthand the natural history of ideas—the patterns of their variation, inheritance, and selection in the cultural landscape. In place of Darwin’s oceanic islands, Hughes visits the “mind islands” of Native American tribes. Instead of finches, Hughes searches for signs of natural selection among the tepees.     With a knack for finding the humor in the quirks of the American cultural landscape, Hughes takes us on a tour from the Mall of America in Minneapolis to what he calls the “maul” of America—Custer’s last stand—stopping at road-sides and discoursing on sandwiches, the shape of cowboy hats, the evolution of barn roofs, the wording of jokes, the wearing of moustaches, and, of course, the telling features from tepees of different tribes. Original, witty, and engaging, On the Origin of Tepees offers a fresh way of understanding both our ideas and ourselves.

    But what were and are the true potentates of our planet? Insects, says Scott Richard Shaw—millions and millions of insect species. Starting in the shallow oceans of ancient Earth and ending in the far reaches of outer space—where, Shaw proposes, insect-like aliens may have achieved similar preeminence—Planet of the Bugs spins a sweeping account of insects’ evolution from humble arthropod ancestors into the bugs we know and love (or fear and hate) today. Leaving no stone unturned, Shaw explores how evolutionary innovations such as small body size, wings, metamorphosis, and parasitic behavior have enabled insects to disperse widely, occupy increasingly narrow niches, and survive global catastrophes in their rise to dominance. Through buggy tales by turns bizarre and comical—from caddisflies that construct portable houses or weave silken aquatic nets to trap floating debris, to parasitic wasp larvae that develop in the blood of host insects and, by storing waste products in their rear ends, are able to postpone defecation until after they emerge—he not only unearths how changes in our planet’s geology, flora, and fauna contributed to insects’ success, but also how, in return, insects came to shape terrestrial ecosystems and amplify biodiversity. Indeed, in his visits to hyperdiverse rain forests to highlight the current insect extinction crisis, Shaw reaffirms just how crucial these tiny beings are to planetary health and human survival. In this age of honeybee die-offs and bedbugs hitching rides in the spines of library books, Planet of the Bugs charms with humor, affection, and insight into the world’s six-legged creatures, revealing an essential importance that resonates across time and space.

    This seems to have been the case even from the first recognition of the Neanderthals as a species. The first Neanderthal fossil discovery was that of a child’s skull in Belgium in 1829, but it was badly damaged. Another would be discovered in 1856 in a limestone mine of the Neanderthal region of what is present-day Germany, and a skull with differing distinct traits (indicating a different species than the Neanderthals) would be discovered just over a decade later in southwestern France. The latter specimen would come to be recognized as an example of the species Homo Sapiens, and these anatomically modern humans arrived in Europe between 45,000 and 43,000 years ago, around the time the Neanderthals are believed to started going extinct. The Neanderthals are a member of the genus Homo just like Homo sapiens and share roughly 99.7% of their DNA with modern humans (Reynolds and Gallagher 2012). Both species even lived briefly during the same time in Eurasia. However, the Neanderthals evolved separately in Europe, away from modern humans, who evolved in Africa. Physically, the Neanderthal skeleton was much more robust, suggesting that there was more room for muscle attachment. However, while Neanderthals were stronger than modern humans, the average height of the Neanderthal male was shorter, standing at only about 5’5 tall. Other physical characteristics that set the Neanderthals apart from modern humans were certain skull traits. The skull in general was low and elongated, featuring a sloping forehead with an occipital bun (a bone projection at the back of the skull), whereas modern humans have a more vertical forehead with no occipital bun. The cranial capacity of the Neanderthal skull was also greater than the modern human at 1,500–1,740 cc, and it lacked a chin and had more circular eye orbits, in contrast to Homo sapiens, which have a chin and tend to feature more rectangular eye orbits (Wolpoff 1999). Despite these differences, the Neanderthals may have been recognizable enough to interact with Homo sapiens or even blend in with Homo sapiens for the thousands of years they lived together in Europe. The Neanderthals lived in Europe and Asia for nearly 200,000 years and thrived in these regions, but they went extinct between 40,000 and 30,000 years ago, around the same time that modern humans began arriving in Europe. This has prompted much speculation as to the nature of the interactions between Neanderthals and Homo sapiens, especially since some researchers believe they interacted with each other for over 5,000 years before the Neanderthals began going extinct at different times across Europe. One hypothesis is that Homo sapiens displaced the Neanderthals and were better suited for the environment, and it is obviously possible if not likely that these two groups had become competitors for food and other resources, with Homo sapiens being more successful in the end. If such close interactions were taking place, there is also a possibility that the relatively new-to-Europe Homo sapiens brought pathogens from Africa with them that were unknown to the Neanderthal’s immune system. A more recent example of this type of resulting interaction is the European expansion into the Americas, which brought diseases like smallpox that the natives of America had never experienced before, especially diseases resulting from the domestication of animals. It is possible that the domestication of the dog by Homo sapiens may have contributed in spreading foreign diseases among the Neanderthals.

    Is it in our genes? The structure of our brains? Our genome may determine our eye color and even aspects of our personality. But our friendships, failures, and passions also shape who we are. The question is: how?Sebastian Seung, a dynamic professor at MIT, is on a quest to discover the biological basis of identity. He believes it lies in the pattern of connections between the brain’s neurons, which change slowly over time as we learn and grow. The connectome, as it’s called, is where our genetic inheritance intersects with our life experience. It’s where nature meets nurture.Seung introduces us to the dedicated researchers who are mapping the brain’s connections, neuron by neuron, synapse by synapse. It is a monumental undertaking—the scientific equivalent of climbing Mount Everest—but if they succeed, it could reveal the basis of personality, intelligence, memory, and perhaps even mental disorders. Many scientists speculate that people with anorexia, autism, and schizophrenia are "wired differently," but nobody knows for sure. The brain’s wiring has never been clearly seen.In sparklingly clear prose, Seung reveals the amazing technological advances that will soon help us map connectomes. He also examines the evidence that these maps will someday allow humans to "upload" their minds into computers, achieving a kind of immortality.Connectome is a mind-bending adventure story, told with great passion and authority. It presents a daring scientific and technological vision for at last understanding what makes us who we are. Welcome to the future of neuroscience.

    Wright unveils the genetic strategies behind everything from our sexual preferences to our office politics--as well as their implications for our moral codes and public policies. Illustrations.

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    In biology labs across the world, fruit flies are turning up answers to some of the basic questions of life. It's business as usual for the fly, which for generations has been defining biology's major landmarks. From genetics to development, behavior to aging, and evolution to the origin of species, the fruit fly has been a key player in some of the twentieth century's greatest biological discoveries.Techniques to pinpoint genes that play a role in human disease depend on genetic mapmaking principles first established with the fly. It was experiments on fruit flies that opened our eyes to the dangers of radiation to human health. In fact, everything from gene therapy to cloning to the Human Genome Project is built on the foundation of fruit fly research. Despite its many achievements, the fruit fly remains an unsung hero in the history of science. At last, here is a book that gives the fly its long overdue credit.In a highly original, witty, and irreverent style, Martin Brookes takes us through successive stages in the life cycle of the fly, each illustrating an important concept in biology. Some, such as the fundamentals of heredity, are well established; others, such as sexual warfare, learning, and memory, are still in their infancy. But whether flies are getting high on crack cocaine, enjoying the pleasures and pains of a boozy night out, being trained by punishment and reward, or struggling with insomnia, this book provides a glimpse of how one short life has informed almost every aspect of human existence. The result is a broad introduction to biology with insights into the practical realities of science.Often dismissed as irrelevant outside academic circles, the fruit fly, through this distinctive biography, will come to be recognized for what it really is: an icon of twentieth-century science and a window on our own biological world.

    How does Jane Goodall’s relationship with her dog Rusty inform her thinking about our relationship to other species? Which time and place would Jared Diamond most prefer to live in, in light of his work on the role of chance in history? What does driving a sports car have to do with Steven Weinberg’s quest for the “theory of everything”? Physicist and journalist Stefan Klein’s intimate conversations with nineteen of the world’s best-known scientists (including three Nobel Laureates) let us listen in as they talk about their paradigm-changing work—and how it is deeply rooted in their daily lives. • Cosmologist Martin Rees on the beginning and end of the world • Evolutionary biologist Richard Dawkins on egoism and selflessness • Neuroscientist V. S. Ramachandran on consciousness • Molecular biologist Elizabeth Blackburn on aging • Philosopher Peter Singer on morality • Physician and social scientist Nicholas Christakis on human relationships • Biochemist Craig Venter on the human genome • Chemist and poet Roald Hoffmann on beauty

    Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences.In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility.A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

    The science of complexity studies how single elements, such as a species or a stock, spontaneously organize into complicated structures like ecosystems and economies; stars become galaxies, and snowflakes avalanches almost as if these systems were obeying a hidden yearning for order. Drawing from diverse fields, scientific luminaries such as Nobel Laureates Murray Gell-Mann and Kenneth Arrow are studying complexity at a think tank called The Santa Fe Institute. The revolutionary new discoveries researchers have made there could change the face of every science from biology to cosmology to economics. M. Mitchell Waldrop's groundbreaking bestseller takes readers into the hearts and minds of these scientists to tell the story behind this scientific revolution as it unfolds.

    Filled with data about the Earth, Moon, the planets, the stars, our Galaxy, and the myriad galaxies in deep space, it also reveals the latest scientific discoveries about black holes, quasars, and the origins of the Universe. Written by a premier astronomy expert, this book begins with a discussion of the Sun, from sunspots to solar eclipses. It then features over 100 tables on characteristics of the Moon, and the names, positions, sizes, and other key descriptors of all the planets and their satellites. The book tabulates solar and lunar eclipse, comets, close-approach asteroids, and significant meteor showers dates. Twenty-four maps show the surface features of the planets and their moons. The author then looks to the stars, their distances and movements, and their detailed classification and evolution. Forty-eight star charts cover both northern and southern hemispheres, enabling you to track down and name the main stars in all the constellations. The maps are supported by detailed tables of the names, positions, magnitudes, and spectra of the main stars in each constellation, along with key data on galaxies, nebulae, and clusters. There is a useful catalogue of the world's great telescopes and observatories, a history of astronomy and of space research, and biographies of 250 astronomers who have been most influential in developing the current understanding of the subject.