We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    From the research biologist who stung himself with every conceivable insect to the world's most murderous mammals, this book explores oft-ignored but alluring facets of biology, anatomy, space exploration, nature, and more. Featuring interviews with leading researchers in the field and a large dose of wit, the author reveals the most intriguing real-world applications of science in all their glory.

    He traced the ownership of individual copies through the hands of saints, heretics, scalawags, and bibliomaniacs. He was called as the expert witness in the theft of one copy, witnessed the dramatic auction of another, and proves conclusively that "De revolutionibus" was as inspirational as it was revolutionary. Part biography of a book, part scientific exploration, part bibliographic detective story, "The Book Nobody Read" recolors the history of cosmology and offers new appreciation of the enduring power of an extraordinary book and its ideas.

    In Consilience  (a word that originally meant "jumping together"), Edward O. Wilson renews the Enlightenment's search for a unified theory of knowledge in disciplines that range from physics to biology, the social sciences and the humanities.Using the natural sciences as his model, Wilson forges dramatic links between fields. He explores the chemistry of the mind and the genetic bases of culture. He postulates the biological principles underlying works of art from cave-drawings to Lolita. Presenting the latest findings in prose of wonderful clarity and oratorical eloquence, and synthesizing it into a dazzling whole, Consilience is science in the path-clearing traditions of Newton, Einstein, and Richard Feynman.

    Darrell Huff runs the gamut of every popularly used type of statistic, probes such things as the sample study, the tabulation method, the interview technique, or the way the results are derived from the figures, and points up the countless number of dodges which are used to fool rather than to inform.

    From the United States Memory Championship to deep within the author's own mind, this is an electrifying work of journalism that reminds us that, in every way that matters, we are the sum of our memories.

    It can be microscopic, yet also accounts for the largest organisms ever recorded, living for millennia and weighing tens of thousands of tonnes. Its ability to digest rock enabled the first life on land, it can survive unprotected in space, and thrives amidst nuclear radiation.In this captivating adventure, Merlin Sheldrake explores the spectacular and neglected world of fungi: endlessly surprising organisms that sustain nearly all living systems. They can solve problems without a brain, stretching traditional definitions of ‘intelligence’, and can manipulate animal behaviour with devastating precision. In giving us bread, alcohol and life-saving medicines, fungi have shaped human history, and their psychedelic properties, which have influenced societies since antiquity, have recently been shown to alleviate a number of mental illnesses. The ability of fungi to digest plastic, explosives, pesticides and crude oil is being harnessed in break-through technologies, and the discovery that they connect plants in underground networks, the ‘Wood Wide Web’, is transforming the way we understand ecosystems. Yet they live their lives largely out of sight, and over ninety percent of their species remain undocumented.Entangled Life is a mind-altering journey into this hidden kingdom of life, and shows that fungi are key to understanding the planet on which we live, and the ways we think, feel and behave. The more we learn about fungi, the less makes sense without them.

    Planetary science has mainly been a descriptive science, but it is becoming increasingly experimental. The space probes that went up between the 1960s and 1990s were primarily generalists-they collected massive amounts of information so that scientists could learn what questions to pursue. But recent missions have become more focused: Scientists know better what information they want and how to collect it. Even now probes are on their way to Mercury, Venus, Mars, and Pluto, with Europa-one of Jupiter's moons-on the agenda. In a sweeping look into the manifold objects inhabiting the depths of space, Lives of the Planets delves into the mythology and the knowledge humanity has built over the ages. Placing our current understanding in historical context, Richard Corfield explores the seismic shifts in planetary astronomy and probes why we must change our perspective of our place in the universe. In our era of extraordinary discovery, this is the first comprehensive survey of this new understanding and the history of how we got here.

    Sixty-six million years ago, the Earth’s most fearsome creatures vanished. Today they remain one of our planet’s great mysteries. Now The Rise and Fall of the Dinosaurs reveals their extraordinary, 200-million-year-long story as never before.In this captivating narrative (enlivened with more than seventy original illustrations and photographs), Steve Brusatte, a young American paleontologist who has emerged as one of the foremost stars of the field—naming fifteen new species and leading groundbreaking scientific studies and fieldwork—masterfully tells the complete, surprising, and new history of the dinosaurs, drawing on cutting-edge science to dramatically bring to life their lost world and illuminate their enigmatic origins, spectacular flourishing, astonishing diversity, cataclysmic extinction, and startling living legacy. Captivating and revelatory, The Rise and Fall of the Dinosaurs is a book for the ages.Brusatte traces the evolution of dinosaurs from their inauspicious start as small shadow dwellers—themselves the beneficiaries of a mass extinction caused by volcanic eruptions at the beginning of the Triassic period—into the dominant array of species every wide-eyed child memorizes today, T. rex, Triceratops, Brontosaurus, and more. This gifted scientist and writer re-creates the dinosaurs’ peak during the Jurassic and Cretaceous, when thousands of species thrived, and winged and feathered dinosaurs, the prehistoric ancestors of modern birds, emerged. The story continues to the end of the Cretaceous period, when a giant asteroid or comet struck the planet and nearly every dinosaur species (but not all) died out, in the most extraordinary extinction event in earth’s history, one full of lessons for today as we confront a “sixth extinction.”Brusatte also recalls compelling stories from his globe-trotting expeditions during one of the most exciting eras in dinosaur research—which he calls “a new golden age of discovery”—and offers thrilling accounts of some of the remarkable findings he and his colleagues have made, including primitive human-sized tyrannosaurs; monstrous carnivores even larger than T. rex; and paradigm-shifting feathered raptors from China.An electrifying scientific history that unearths the dinosaurs’ epic saga, The Rise and Fall of the Dinosaurs will be a definitive and treasured account for decades to come.

    Marvel at the Dual Slit experiment as a tiny atom passes through 2 separate openings at the same time. Ponder the peculiar communication of quantum particles, which can remain in touch no matter how far apart. Join the genius jewel thief as he carries out a quantum measurement on a diamond without ever touching the object in question. With its clean, colorful layout and conversational tone, this text will hook you into the conundrum that is quantum mechanics.

    As these divides deepen, we have lost the sense of ethical obligation to others that was crucial to the rise of post-war social democracy. So far these rifts have been answered only by the revivalist ideologies of populism and socialism, leading to the seismic upheavals of Trump, Brexit, and the return of the far-right in Germany. We have heard many critiques of capitalism but no one has laid out a realistic way to fix it, until now.In a passionate and polemical book, celebrated economist Paul Collier outlines brilliantly original and ethical ways of healing these rifts—economic, social and cultural—with the cool head of pragmatism, rather than the fervor of ideological revivalism. He reveals how he has personally lived across these three divides, moving from working-class Sheffield to hyper-competitive Oxford, and working between Britain and Africa, and acknowledges some of the failings of his profession.Drawing on his own solutions as well as ideas from some of the world’s most distinguished social scientists, he shows us how to save capitalism from itself—and free ourselves from the intellectual baggage of the twentieth century.

    From that modest beginning, container shipping developed into a huge industry that made the boom in global trade possible. "The Box" tells the dramatic story of the container's creation, the decade of struggle before it was widely adopted, and the sweeping economic consequences of the sharp fall in transportation costs that containerization brought about.Published on the fiftieth anniversary of the first container voyage, this is the first comprehensive history of the shipping container. It recounts how the drive and imagination of an iconoclastic entrepreneur, Malcom McLean, turned containerization from an impractical idea into a massive industry that slashed the cost of transporting goods around the world and made the boom in global trade possible.But the container didn't just happen. Its adoption required huge sums of money, both from private investors and from ports that aspired to be on the leading edge of a new technology. It required years of high-stakes bargaining with two of the titans of organized labor, Harry Bridges and Teddy Gleason, as well as delicate negotiations on standards that made it possible for almost any container to travel on any truck or train or ship. Ultimately, it took McLean's success in supplying U.S. forces in Vietnam to persuade the world of the container's potential.Drawing on previously neglected sources, economist Marc Levinson shows how the container transformed economic geography, devastating traditional ports such as New York and London and fueling the growth of previously obscure ones, such as Oakland. By making shipping so cheap that industry could locate factories far from its customers, the container paved the way for Asia to become the world's workshop and brought consumers a previously unimaginable variety of low-cost products from around the globe.

    The theme of Heisenberg's exposition is that words and concepts familiar in daily life can lose their meaning in the world of relativity and quantum physics. This in turn has profound philosophical implications for the nature of reality and for our total world view.

    In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation. Among the questions the obituary—and consequent outcry—prompted were, Who are the role models for today’s female scientists, and where can we find the stories that cast them in their true light?      Headstrong delivers a powerful, global, and engaging response. Covering Nobel Prize winners and major innovators, as well as lesser-known but hugely significant scientists who influence our every day, Rachel Swaby’s vibrant profiles span centuries of courageous thinkers and illustrate how each one’s ideas developed, from their first moment of scientific engagement through the research and discovery for which they’re best known. This fascinating tour reveals these 52 women at their best—while encouraging and inspiring a new generation of girls to put on their lab coats.

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”