To reach this unique audience, Whitlock and Schluter motivate learning with interesting biological and medical examples; they emphasize intuitive understanding; and they focus on real data. The book covers basic topics in introductory statistics, including graphs, confidence intervals, hypothesis testing, comparison of means, regression, and designing experiments. It also introduces the principles behind such modern topics as likelihood, linear models, meta-analysis and computer-intensive methods. Instructors and students consistently praise the book's clear and engaging writing, strong visualization techniques, and its variety of fascinating and relevant biological examples.

    For advanced crafters, this book instructs on features such as modes and functions, and teaches how to create with color, texture, and dimension. A cutting guide teaches the perfect settings to cut every type of material. A separate chapter introduces the new features of Cricut Expression™ 2 and explains how it differs from the original Expression machine. More than 50 creative projects inspire ideas for home décor, gifts, parties, cards, and scrapbook layouts.

    For over forty years he has dominated Hollywood and his success both in front of and behind the camera has assured his place in cinema history alongside such superstars as Marlon Brando, John Wayne and Robert De Niro..."Clint" reveals the man behind the myth. Bestselling author Douglas Thompson draws on exclusive interviews with the star, to provide the definitive portrait of Clint Eastwood. From his early days as a jobbing actor on $75 a week to his directorial triumph with "Million Dollar Baby", "Clint" reveals the personal highlights of one of the most celebrated careers in cinema history.

    Our species emerged out of the depths of time into a world already populated by these great carnivores. Before we mastered iron and later developed firearms, we had few defences against bears--only watchful caution and elaborate ceremonies and sacrifices to ward off fear.Where human populations grow, bears have traditionally dwindled or disappeared. But when we return to the wild, to places where bears still survive, all our primeval fears awaken again. The risk of an automobile accident on the way to bear country far outstrips the risk of a close-range encounter with a bear, but it's the bear that worries us as we hurtle down the pavement at a hundred kilometres an hour.In this timely and sensitive book, Kevin Van Tighem calls on decades of experience, knowledge and understanding in order to enlighten readers about our relationship with and attitude toward bears. Along the way we are confronted with the realities confronting these great animals as a result of our ever-expanding human population and their ever-shrinking natural habitat. Through historical research, field observation, practical advice, personal anecdotes and an array of stunning photos, Van Tighem has written a comprehensive book that is meant to demystify bears in order to promote a deeper understanding of these powerful yet vulnerable creatures.

    But when Paco was struck down by a disease that left him unable to walk, Hickam was faced with a terrible decision, let his beloved cat live in misery or put him to sleep. Before that decision could be made, the space mission Hickam was working on needed to be rescued and there was only one sure way to save it: Paco's magic meow! This is a true story of the space age that is also a delightful tale of the love between an engineer and his cat.

    Thanks largely to YouTube clips posted by the sloth orphanage in Costa Rica, sloths have attracted a vast audience of admirers. Instead of seeing them as ridiculous anachronisms of which we know little, they have turned into creatures considered by many to be the most endearing on earth.Over much the same period, scientific investigations have also changed our view of sloths. No longer are they seen as total misfits in the modern world but, in the words of one specialist sloth investigator, they are 'masters of an alternative lifestyle'.In this wonderfully entertaining celebration of this most unique of creatures, William Hartston reveals the fascinating history of the sloth, from the prehistoric ground sloth to modern pygmy sloths in Panama, explores the current state of the science of sloths and reveals the truth behind sloth behaviour.

    He decried the internment of Japanese-Americans in World War Two, agitated against nuclear weapons, promoted vitamin C as a cure for the common cold and researched the idea of DNA.

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    The Grand Question of Lifes Origins 2. The Historical Setting of Origins Research 3. What Is Life? 4. Is There Life on Mars? 5. Earths Oldest Fossils 6. Fossil Isotopes 7. Molecular Biosignatures 8. Emergence 9. The Miller-Urey Experiment 10. Life from the Bottom of the Sea 11. The Deep, Hot Biosphere 12. Experiments at High Pressure 13. More Experiments Under Pressure 14. Deep Space Dust, Molten Rock, and Zeolite 15. Macromolecules and the Tree of Life 16. Lipids and Membrane Self-Organization 17. Life on Clay, Clay as Life 18. Lifes Curious Handedness 19. Self-Replicating Molecular Systems 20. Günter Wächtershäusers Grand Hypothesis 21. The RNA World 22. The Pre-RNA World 23. Natural Selection and Competition 24. Three Scenarios for the Origin of Life

    Boundless works with subject matter experts to select the best open educational resources available on the web, review the content for quality, and create introductory, college-level textbooks designed to meet the study needs of university students.<br><br>This textbook covers:<br><br><b>Human Anatomy and Physiology Introduction</b> -- Anatomy and Physiology Overview, Life, Homeostasis, Anatomical Terms, Clinical Cases<br><br><b>General Chemistry</b> -- Matter and Energy, Element Properties: Atomic structure, Chemical Bonds, Chemical Reactions, Inorganic Compounds, Organic Compounds<br><br><b>Cellular Structure and Function</b> -- the study of cells, Cell membranes and the fluid mosaic model, Transport across membranes, How reception works in cell signaling, Nucleus and Ribosomes, Organelles, The Cytoskeleton, External cellular components, Cell division: process and importance, The cell cycle, Transcription and translation, RNA processing, Translation to a polypeptide, Transcription, Apoptosis signals an orderly cell death<br><br><b>Tissues</b> -- Epithelial Tissue, Cell Junctions, Clinical Cases, Tissue Repair, Tissue Development, Cancer, Connective Tissue, Membranes, Nervous Tissue<br><br><b>The Integumentary System</b> -- The Skin, Accessory Structures of the Skin, Functions of the Integumentary System, Wound Healing, Integumentary System Development, Skin Disorders, Imbalances, Diseases, and Clinical Cases<br><br><b>Skeletal Tissue</b> -- Cartilage, Bone Classification, Bone Formation, Bone and Calcium, Bone Development, Bone Diseases, Disorders, Imbalances, and Clinical Cases<br><br><b>The Skeletal System</b> -- Overview of the Musculoskeletal system, Divisions of the Skeletal System, The Axial Skeleton, Skull, Hyoid Bone, Vertebral Column, Thorax, Clinical Cases of the Axial Skeleton, The Appendicular Skeleton, The Pectoral (Shoulder) Girdle, Upper Limb, The Pelvic (Hip) Girdle, Lower Limb, Skeletal System Development, Clinical Cases of the Appendicular Skeleton<br><br><b>Joints</b> -- Classification of Joints, Synovial Joints, Joint Development, Clinical Cases<br><br><b>Muscle Tissue</b> -- Overview of Muscle Tissue, Skeletal Muscle, Control of Muscle Tension, Muscle Metabolism, Exercise and Skeletal Muscle Tissue, Smooth Muscle, Clinical Cases: Muscle Disorders, Development of Muscle<br><br><b>The Muscular System</b> -- Overview of the Muscular System, Head And Neck Muscles, Trunk Muscles, Muscles of the Upper Limb, Muscles of the Lower Limb, Clinical Cases and Muscular System Disorders<br><br><b>Nervous Tissue</b> -- Overview of the Nervous System, Neuroglia, Neurons, Collections of Nervous Tissue, Neurophysiology<br><br><b>Central Nervous System (CNS)</b> -- The Brain, Consciousness, Sleep, Language, and Memory, Protection of the Brain, Parts of The Brain Stem, The Cerebellum, The Diencephalon, Cerebral Cortex (or Cerebral Hemispheres), Functional Systems of the Cerebral Cortex, Development of the CNS, Brain Disorders and Clinical Cases, The Spinal Cord, Spinal Cord Anatomy, Disorders and Clinical Cases of the Spinal Cord<br><br><b>Peripheral Nervous System (PNS)</b> -- Sensation, Sensory Receptors, Somatosensory System, Nerves, Cranial Nerves, Spinal Nerves, Distribution of Spinal Nerves, Motor Activity, Motor Pathways, Reflexes, Pain, Development of the Nervous System, Disorders of Spinal Nerves and Clinical Cases<br><br><b>Autonomic Nervous System (ANS)</b> -- Autonomic Nervous System, ANS Anatomy, Physiology of ANS,

    With a logical, body-systems organization and engaging terminology exercises throughout, it's your key to communicating confidently and effectively with other health care professionals.Systematic approach to terminology prepares you to recognize and define new words as you encounter them and build the medical vocabulary you'll need in the health care setting.Pronunciation key provides quick access to frequently referenced material.Complimentary and Alternative Medicine terms boxes highlight words and phrases associated with this increasingly popular discipline.Case studies encourage critical thinking and demonstrate how to apply the information you've learned.Terminology flash cards, included with every book, give you valuable review and self-assessment tools you can take anywhere for study on the go.Evolve resources enhance your learning and reinforcement opportunities with additional exercises, a Spanish/English glossary, and the Body Spectrum Electronic Anatomy Coloring Book.Medical Terminology Online, available at an additional charge, gives you access to a complete online course for the most advanced learning and understanding.New terms and abbreviations familiarize you with the latest terminology in use in health care.New images and illustrations visually acquaint you with pathologic information and procedures you'll encounter in the clinical setting.Enhanced chapter features highlight important concepts and provide guidance for more effective learning and study.CD references within the text direct you to expanded learning opportunities on the companion CD.More than 20 new medical records let you practice medical terminology using the forms you'll encounter in the clinical setting.New icons make it easy to distinguish a variety of helpful boxes and reference the material you need quickly.Answers to review exercises help you gauge your strengths and weaknesses and configure the most effective study plan for you.Website boxes refer you to valuable content you can access online for further learning.Revised pharmacy appendix helps you easily reference key pharmaceutical terms.The vastly updated companion CD provides fun alternatives for reinforcing what you've learned with new learning games, including Medical Millionaire and Termbusters.Enhanced audio companion, available on CD or as iTerms downloads for portable media players, helps you perfect your pronunciation skills and confidently use the terms you've learned in practice.

    A who's who of pathology experts delivers the most dependable, current, and complete coverage of today's essential pathology knowledge. At the same time, masterful editing and a practical organization make mastering every concept remarkably easy. Online access via Student Consult includes self-assessment and review questions, interactive case studies, downloadable images, videos, and a virtual microscope that lets you view slides at different magnifications. The result remains the ideal source for an optimal understanding of pathology. Offers the most authoritative and comprehensive, yet readable coverage available in any pathology textbook, making it ideal for USMLE or specialty board preparation as well as for course work. Includes access to the complete contents online via Student Consult, along with self-assessment and review questions, over 100 interactive clinical case studies, videos, and a virtual microscope that lets users view slides at different magnifications.Delivers a state-of-the-art understanding of the pathologic basis of disease through completely updated coverage, including the latest cellular and molecular biology.Demonstrates every concept visually with over 1,600 full-color photomicrographs and conceptual diagrams - many revised for even better quality.Facilitates learning with an outstanding full-color, highly user-friendly design.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    Just ask biotechnologist Matti Leisola. It all started when a student loaned the Finnish scientist a book criticizing evolutionary theory. Leisola reacted angrily, and set out to defend evolution, but found his efforts raised more questions than they answered. He soon morphed into a full-on Darwin skeptic, even as he was on his way to becoming a leading bio-engineer.Heretic is the story of Leisola's adventures making waves-and many friends and enemies-at major research labs and universities across Europe. Tracing his investigative path, the book draws on Leisola's expertise in molecular biology to show how the evidence points more strongly than ever to the original biotechnologist-a designing intelligence whose skill and reach dwarf those of even our finest bioengineers, and leave blind evolution in the dust.Endorsements "Award-winning Finnish biotechnologist Matti Leisola has written a fascinating account of what happens when a scientist follows the evidence wherever it leads. Leisola's account of how he succeeded should inspire up-and-coming scientists who face the same challenge." Biologist Jonathan Wells, PhD, author of Icons of Evolution and Zombie Science "Scientists, like all other intellectuals, have ideas about what constitutes and what does not constitute reality. However, they are often not aware-and sometimes not ready to admit-that such ideas represent the principles of their philosophy. Leisola and Witt's Heretic is a unique first-hand account of the life-long adventures of a scientist who dared to challenge philosophical principles of colleague scientists. In my opinion, the outcome shows that to many scientists their philosophy is dearer than their science." Biochemist and inventor Branko Kozulic, PhD "This book is an exciting story about how a scientist's relentless search for truth makes him a heretic in the eyes of a cultural community more concerned about prestige than principle." Tapio Puolimatka, PhD and EdD, University of Jyvaskyla, Finland "This book is a personal, strong, and motivated plea for intelligent design (ID) and 'swims against the current' of Darwinian evolution, now generally accepted in scientific circles and society. I personally do not endorse ID, but I am a good friend of the author, whom I also highly respect as a scientist active in academia and in the biotech industry over so many years. Heretic inspires readers to think critically and to open up a civilized discussion on neo-Darwinism versus ID. It covers the science and philosophical parts adequately; it is accessible to a large readership; and statements are underpinned by relevant research and literature data. Its value lies in the author's lifelong engagement and personal crusade to stimulate the public debate among scientists as well as laymen over Darwinism (chance/random mutation and natural selection) versus ID, a vision that Leisola strongly advocates." Dr. Erick J. Vandamme, Emeritus Professor of Bioscience Engineering, Ghent University, Belgium "Matti Leisola has written the exciting story of almost the entire spectrum of aberrant motives, absurd fears, and unreasonable reactions to intelligent design (ID) by evolutionary scientists, clergymen, and church institutions alike, notably during his career as a scientist over the last some forty years. I would add a word on the fears of so many critics that accepting ID also means accepting the dogmata of some 1700 years of church history. ID is thoroughly neutral concerning such topics. So, the reader is invited to carefully check the historical and, what is more, the enormous wealth of scientific data Matti Leisola has presented in the present book: Test them carefully with an open mind and form your own independent opinion!" Dr. Wolf-Ekkehard Lonnig, geneticist, Cologne,