For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family’s spoons, tried on their underpants and tested their chamber pots.Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions. Women wore makeup made with mercury and lead. Men rubbed turds on their bald spots. Physicians prescribed mercury enemas, arsenic skin cream, drinks of lead filings, and potions of human fat and skull, fresh from the executioner. The most gorgeous palaces were little better than filthy latrines. Gazing at gorgeous portraits of centuries past, we don’t see what lies beneath the royal robes and the stench of unwashed bodies; the lice feasting on private parts; and worms nesting in the intestines.In The Royal Art of Poison, Eleanor Herman combines her unique access to royal archives with cutting-edge forensic discoveries to tell the true story of Europe’s glittering palaces: one of medical bafflement, poisonous cosmetics, ever-present excrement, festering natural illness, and, sometimes, murder.

    His contribution to our understanding not only of mental illness but also of the human condition is truly stunning.The Noonday Demon examines depression in personal, cultural, and scientific terms. Drawing on his own struggles with the illness and interviews with fellow sufferers, doctors and scientists, policymakers and politicians, drug designers and philosophers, Solomon reveals the subtle complexities and sheer agony of the disease. He confronts the challenge of defining the illness and describes the vast range of available medications, the efficacy of alternative treatments, and the impact the malady has had on various demographic populations around the world and throughout history. He also explores the thorny patch of moral and ethical questions posed by emerging biological explanations for mental illness.The depth of human experience Solomon chronicles, the range of his intelligence, and his boundless curiosity and compassion will change the reader's view of the world.

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong.Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

    But Cullen was no mercy killer, nor was he a simple monster. He was a favorite son, husband, beloved father, best friend, and celebrated caregiver. Implicated in the deaths of as many as 300 patients, he was also perhaps the most prolific serial killer in American history.Cullen's murderous career in the world's most trusted profession spanned sixteen years and nine hospitals across New Jersey and Pennsylvania. When, in March of 2006, Charles Cullen was marched from his final sentencing in an Allentown, Pennsylvania, courthouse into a waiting police van, it seemed certain that the chilling secrets of his life, career, and capture would disappear with him. Now, in a riveting piece of investigative journalism nearly ten years in the making, journalist Charles Graeber presents the whole story for the first time. Based on hundreds of pages of previously unseen police records, interviews, wire-tap recordings and videotapes, as well as exclusive jailhouse conversations with Cullen himself and the confidential informant who helped bring him down, THE GOOD NURSE weaves an urgent, terrifying tale of murder, friendship, and betrayal.Graeber's portrait of Cullen depicts a surprisingly intelligent and complicated young man whose promising career was overwhelmed by his compulsion to kill, and whose shy demeanor masked a twisted interior life hidden even to his family and friends. Were it not for the hardboiled, unrelenting work of two former Newark homicide detectives racing to put together the pieces of Cullen's professional past, and a fellow nurse willing to put everything at risk, including her job and the safety of her children, there's no telling how many more lives could have been lost.In the tradition of In Cold Blood, THE GOOD NURSE does more than chronicle Cullen's deadly career and the breathless efforts to stop him; it paints an incredibly vivid portrait of madness and offers a penetrating look inside America's medical system. Harrowing and irresistibly paced, this book will make you look at medicine, hospitals, and the people who work in them, in an entirely different way.

    Many books on the plague rely on statistics to tell the story: how many people died; how farm output and trade declined. But statistics can’t convey what it was like to sit in Siena or Avignon and hear that a thousand people a day are dying two towns away. Or to have to chose between your own life and your duty to a mortally ill child or spouse. Or to live in a society where the bonds of blood and sentiment and law have lost all meaning, where anyone can murder or rape or plunder anyone else without fear of consequence.In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    Beginning with his family’s odyssey, In a Different Key tells the extraordinary story of this often misunderstood condition, and of the civil rights battles waged by the families of those who have it. Unfolding over decades, it is a beautifully rendered history of ordinary people determined to secure a place in the world for those with autism—by liberating children from dank institutions, campaigning for their right to go to school, challenging expert opinion on what it means to have autism, and persuading society to accept those who are different.  It is the story of women like Ruth Sullivan, who rebelled against a medical establishment that blamed cold and rejecting “refrigerator mothers” for causing autism; and of fathers who pushed scientists to dig harder for treatments. Many others played starring roles too: doctors like Leo Kanner, who pioneered our understanding of autism; lawyers like Tom Gilhool, who took the families’ battle for education to the courtroom; scientists who sparred over how to treat autism; and those with autism, like Temple Grandin, Alex Plank, and Ari Ne’eman, who explained their inner worlds and championed the philosophy of neurodiversity. This is also a story of fierce controversies—from the question of whether there is truly an autism “epidemic,” and whether vaccines played a part in it; to scandals involving “facilitated communication,” one of many treatments that have proved to be blind alleys; to stark disagreements about whether scientists should pursue a cure for autism. There are dark turns too: we learn about experimenters feeding LSD to children with autism, or shocking them with electricity to change their behavior; and the authors reveal compelling evidence that Hans Asperger, discoverer of the syndrome named after him, participated in the Nazi program that consigned disabled children to death.<

    It's the late 1960s and homosexuality has only just been legalised, and Jeremy Thorpe, the leader of the Liberal party, has a secret he's desperate to hide. As long as Norman Scott, his beautiful, unstable lover is around, Thorpe's brilliant career is at risk. With the help of his fellow politicians, Thorpe schemes, deceives, embezzles - until he can see only one way to silence Scott for good.The trial of Jeremy Thorpe changed our society forever: it was the moment the British public discovered the truth about its political class. Illuminating the darkest secrets of the Establishment, the Thorpe affair revealed such breath-taking deceit and corruption in an entire section of British society that, at the time, hardly anyone dared believe it could be true.

    Forced to remain inside until they'd "proven" themselves sane, all eight emerged with alarming diagnoses and even more troubling stories of their treatment. Rosenhan's study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever. But, as Cahalan's new research shows, very little in this saga is exactly as it seems. What really happened behind those closed asylum doors, and what does it mean for our understanding of mental illness today?

    The compilation of the OED, begun in 1857, was one of the most ambitious projects ever undertaken. As definitions were collected, the overseeing committee, led by Professor James Murray, discovered that one man, Dr. W. C. Minor, had submitted more than ten thousand. When the committee insisted on honoring him, a shocking truth came to light: Dr. Minor, an American Civil War veteran, was also an inmate at an asylum for the criminally insane.

    In the eighteenth century, this palace was a world of skulduggery, intrigue, politicking, etiquette, wigs, and beauty spots, where fans whistled open like switchblades and unusual people were kept as curiosities. Lucy Worsley's The Courtiers charts the trajectory of the fantastically quarrelsome Hanovers and the last great gasp of British court life. Structured around the paintings of courtiers and servants that line the walls of the King's Staircase of Kensington Palace-paintings you can see at the palace today-The Courtiers goes behind closed doors to meet a pushy young painter, a maid of honor with a secret marriage, a vice chamberlain with many vices, a bedchamber woman with a violent husband, two aging royal mistresses, and many more. The result is an indelible portrait of court life leading up to the famous reign of George III , and a feast for both Anglophiles and lovers of history and royalty.

    Operation Fortitude, which protected and enabled the invasion, and the Double Cross system, which specialized in turning German spies into double agents, deceived the Nazis into believing that the Allies would attack at Calais and Norway rather than Normandy. It was the most sophisticated and successful deception operation ever carried out, ensuring that Hitler kept an entire army awaiting a fake invasion, saving thousands of lives, and securing an Allied victory at the most critical juncture in the war.   The story of D-Day has been told from the point of view of the soldiers who fought in it, the tacticians who planned it, and the generals who led it. But this epic event in world history has never before been told from the perspectives of the key individuals in the Double Cross System. These include its director (a brilliant, urbane intelligence officer), a colorful assortment of MI5 handlers (as well as their counterparts in Nazi intelligence), and the five spies who formed Double Cross’s nucleus: a dashing  Serbian playboy, a Polish fighter-pilot, a bisexual Peruvian party girl, a deeply eccentric Spaniard with a diploma in chicken farming and a volatile Frenchwoman, whose obsessive love for her pet dog very nearly wrecked the entire plan. The D-Day spies were, without question, one of the oddest military units ever assembled, and their success depended on the delicate, dubious relationship between spy and spymaster, both German and British. Their enterprise was saved from catastrophe by a shadowy sixth spy whose heroic sacrifice is revealed here for the first time.   With the same depth of research, eye for the absurd and masterful storytelling that have made Ben Macintyre an international bestseller,  Double Cross is a captivating narrative of the spies who wove a web so intricate it ensnared Hitler’s army and carried thousands of D-Day troops across the Channel in safety.

    . . or it might have been last night, when you watched three episodes in a row. But either way, fifteen years after the show first aired, it's more popular than ever, and fans have only one problem--what to watch, or read, next.Fortunately, Rolling Stone writer Andy Greene has that answer. In his brand-new oral history, The Office: The Untold Story of the Greatest Sitcom of the 2000s, Greene will take readers behind the scenes of their favorite moments and characters. Greene gives us the true inside story behind the entire show, from its origins on the BBC through its impressive nine-season run in America, with in-depth research and exclusive interviews. Fans will get the inside scoop on key episodes from "The Dundies" to "Threat Level Midnight" and "Goodbye, Michael," including behind-the-scenes details like the battle to keep it on the air when NBC wanted to pull the plug after just six episodes and the failed attempt to bring in James Gandolfini as the new boss after Steve Carell left, spotlighting the incredible, genre-redefining show created by the family-like team, who together took a quirky British import with dicey prospects and turned it into a primetime giant with true historical and cultural significance.Hilarious, heartwarming, and revelatory, The Office gives fans and pop culture buffs a front-row seat to the phenomenal sequence of events that launched The Office into wild popularity, changing the face of television and how we all see our office lives for decades to come.

    With a wealth of detail, "A Journal of the Plague Year" seems almost a firsthand account, taking readers through the neighborhoods, houses, and streets that have drastically changed with the rising death toll. The bustle of business and errands gives way to doors marked with the cross to signify a house of death, as well as the dead-carts transporting those struck down to the mass graves as the dead rise in number to nearly 100,000. As the epidemic progresses and the narrator encounters more stories of isolation and horror, Defoe reveals his masterful balance as both a historical and imaginative writer.