hopeful news [for those] suffering from functional bowel disease.”  — New York Times Book ReviewDr. Gershon’s groundbreaking book fills the gap between what you need to know—and what your doctor has time to tell you.Dr. Michael Gershon has devoted his career to understanding the human bowel (the stomach, esophagus, small intestine, and colon). His thirty years of research have led to an extraordinary rediscovery: nerve cells in the gut that act as a brain. This "second brain" can control our gut all by itself. Our two brains—the one in our head and the one in our bowel—must cooperate. If they do not, then there is chaos in the gut and misery in the head—everything from "butterflies" to cramps, from diarrhea to constipation. Dr. Gershon's work has led to radical new understandings about a wide range of gastrointestinal problems including gastroenteritis, nervous stomach, and irritable bowel syndrome.The Second Brain represents a quantum leap in medical knowledge and is already benefiting patients whose symptoms were previously dismissed as neurotic or "it's all in your head."

    Such a simple defect should be fixable, yet despite all of the resources that have been devoted to finding a pharmacological solution, depression remains stubbornly widespread. Why are we losing this fight?In this humane and illuminating challenge to defect models of depression, psychologist Jonathan Rottenberg argues that depression is a particularly severe outgrowth of our natural capacity for emotion. In other words, it is a low mood gone haywire. Drawing on recent developments in the science of mood—and his own harrowing depressive experience as a young adult—Rottenberg explains depression in evolutionary terms, showing how its dark pull arises from adaptations that evolved to help our ancestors ensure their survival. Moods, high and low, evolved to compel us to more efficiently pursue rewards. While this worked for our ancestors, our modern environment—in which daily survival is no longer a sole focus—makes it all too easy for low mood to slide into severe, long-lasting depression.Weaving together experimental and epidemiological research, clinical observations, and the voices of individuals who have struggled with depression, The Depths offers a bold new account of why depression endures—and makes a strong case for de-stigmatizing this increasingly common condition. In so doing, Rottenberg offers hope in the form of his own and other patients’ recovery, and points the way towards new paths for treatment.

    Margaret I. Cuomo is inspired to seek out new strategies for waging a smarter war on cancer.This year, about 1.6 million new cases of cancer will be diagnosed and more than 1,500 people will die "per day." We've been asked to accept the disappointing strategy to "manage cancer as a chronic disease." We've allowed pharmaceutical companies to position cancer drugs that extend life by just weeks and may cost $100,000 for a single course of treatment as breakthroughs. Where is the bold leadership that will transform our system from treatment to prevention? Have we forgotten the mission of the National Cancer Act of 1971 to "conquer cancer"?Through an analysis of more than 40 years of medical evidence and interviews with the top cancer researchers, drug company executives, and health policy advisers, Dr. Cuomo reveals intriguing answers to these questions. She shows us how all cancer stakeholders--the pharmaceutical industry, the government, physicians, and concerned Americans--can change the way we view and fight cancer in this country.

    The growing number of patients being diagnosed with depression, ADD, alcoholism, and other illnesses mean that few people are not touched by it. This book provides a valuable and comprehensible introduction to the subject. It starts with the history of its development as a scientific field, including the identification of major mental illnesses, the rise and fall of the asylum system, and the flourishing of psychoanalysis and other psychotherapies. More than any other branch of medicine, psychiatry has been attacked and criticized. There is a long list of perceived horrors--patient abuse, bizarre medical experiments, mind-control by evil governments, coercion by maniacal hypnotists. Modern psychiatry brings with it new controversies, such as the perceived over-prescription of antidepressants and behavior modifiers for children and teens, or unchecked marketing power of drug companies. This book does not draw conclusions on these issues, but rather provides the reader with a clear understanding of what psychiatry is, and what it does, so that they can draw their own. It is a great reference for anyone with an interest in mental illness and its treatment, students of psychiatry, medicine, psychology, and history of science, and health professionals.

    The New Mind Readers provides a compelling look at the origins, development, and future of these extraordinary tools, revealing how they are increasingly being used to decode our thoughts and experiences--and how this raises sometimes troubling questions about their application in domains such as marketing, politics, and the law.Russell Poldrack takes readers on a journey of scientific discovery, telling the stories of the visionaries behind these breakthroughs. Along the way, he gives an insider's perspective on what is perhaps the single most important technology in cognitive neuroscience today--functional magnetic resonance imaging, or fMRI, which is providing astonishing new insights into the contents and workings of the mind. He highlights both the amazing power and major limitations of these techniques and describes how applications outside the lab often exceed the bounds of responsible science. Poldrack also details the unique and sometimes disorienting experience of having his own brain scanned more than a hundred times as part of a landmark study of how human brain function changes over time.Written by one of the world's leading pioneers in the field, The New Mind Readers cuts through the hype and misperceptions surrounding these emerging new methods, offering needed perspective on what they can and cannot do--and demonstrating how they can provide new answers to age-old questions about the nature of consciousness and what it means to be human.

    It’s almost as much fun, and needs less energy.” — Peter Macinnis, author of 100 Discoveries: The Greatest Breakthroughs in History "How Sex Works manages to inject science writing with the prurient thrill of a gossip rag." —O magazineMedical maverick and New York Times bestselling author of Survival of the Sickest Dr. Sharon Moalem presents an insightful and engaging voyage through the surprising history and evolution of sexual reproduction. Fans of Freakonomics, Blink, You: The Owner’s Manual, and Why Do Men Have Nipples will find many engaging insights in How Sex Works.

     For more than twenty years, Kitty Dukakis battled severe depression with every medication and treatment available. But it wasn't until she tried electroconvulsive therapy- ECT-that she began getting her life back for good. Written with award-winning medical reporter Larry Tye, "Shock" is both the personal story of how ECT dramatically changed Kitty Dukakis's life as well as a captivating look at the science behind ECT, the controversy surrounding it, and the history of its intriguing rebirth in this country. "Shock" explores the stigma afflicting ECT-still a treatment that many hospitals do not administer-and debunks long-held misconceptions about how it is performed. Though some continue to view ECT as a dangerous, even barbaric, procedure, as this book explains there is no scientific evidence to suggest that ECT damages the brain. It can cause side effects like memory loss, but they generally are not far-reaching or long-lasting, especially when newer, lower-impact techniques are employed. In fact, the U.S. surgeon general and the National Institutes of Health agree that for severe depression ECT is safe, and often more effective than antidepressants or psychotherapy. An eye-opening and powerful book about one of the most contentious medical treatments in history, Shock demystifies ECT and brings to life-through Kitty Dukakis's moving account -its impressive capacity to heal. For the millions who suffer from depression, bipolar disorder, and other mental illnesses, it offers real information, practical guidance, and hope.

     Heather Sellers is face-blind-that is, she has prosopagnosia, a rare neurological condition that prevents her from reliably recognizing people's faces. Growing up, unaware of the reason for her perpetual confusion and anxiety, she took what cues she could from speech, hairstyle, and gait. But she sometimes kissed a stranger, thinking he was her boyfriend, or failed to recognize even her own father and mother. She feared she must be crazy. Yet it was her mother who nailed windows shut and covered them with blankets, made her daughter walk on her knees to spare the carpeting, had her practice secret words to use in the likely event of abduction. Her father went on weeklong "fishing trips" (aka benders), took in drifters, wore panty hose and bras under his regular clothes. Heather clung to a barely coherent story of a "normal" childhood in order to survive the one she had. That fairy tale unraveled two decades later when Heather took the man she would marry home to meet her parents and began to discover the truth about her family and about herself. As she came at last to trust her own perceptions, she learned the gift of perspective: that embracing the past as it is allows us to let it go. And she illuminated a deeper truth-that even in the most flawed circumstances, love may be seen and felt. Watch a Video

    But for thousands of years, people have done things like this—and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare. And some of the terrifying detours along the way.Every week, Dr. Sydnee McElroy and her husband Justin amaze, amuse, and gross out (depending on the week) hundreds of thousands of avid listeners to their podcast, Sawbones. Consistently rated a top podcast on iTunes, with over 15 million total downloads, this rollicking journey through thousands of years of medical mishaps and miracles is not only hilarious but downright educational. While you may never even consider applying  boiled weasel to your forehead (once the height of sophistication when it came to headache cures), you will almost certainly face some questionable medical advice in your everyday life (we’re looking at you, raw water!) and be better able to figure out if this is a miracle cure (it’s not) or a scam. Table of Contents:Part One: The Unnerving The Resurrection Men Fun w Galvanism Weird Weight Loss Miracle Cure: Opium Black Plague Heroes of Misguided Medicine: Pliny the Elder Erectile Dysfunction The Doctor Is In: Listener Questions Answered Don’t Drill a Hole in Your HeadPart Two: The Gross Mummy Medicine The Guthole Bromance The Unkillable Phineas Gage Max Drank Poopy Water Heroes of Misguided Medicine: Robert Liston Golden Showers of Health Miracle Cure-All: Radium Dr. John Romulus Brinkley The Doctor Is In Q&A Just (Four) Humour Me The Camel Dung MiraclePart Three: The Weird The Dancing Plague Bad Medicine: Tobacco for Health The Seasick-Proof Saloon Miracle Cure-All: Vinegar The Doctor Is In Q&A Heroes of Misguided MedicinePart Four: The Awesome The Poison Squad Bad Medicine: Self Experimentation Eat Your Chocolate! Heroes of Misguided Medicine Parrot Fever Miracle Cure-All: Honey The Miraculous Polio Vaccine The Doctor Is In

    Along the way, she turns up fresh scientific findings, explores the dark regions of the human brain, and hears the intimate confessions of high-functioning midlife adults who—like you—want to understand exactly what's going on upstairs.Anyone older than forty knows that forgetfulness can be unnerving, frustrating, and sometimes terrifying. With compassion and humor, Jakobson Ramin sets out to discover what midlife forgetfulness is all about—from the perspectives of physiology, psychology, and sociology. Relentless in her search for answers to questions about her own unreliable memory, she explores the factors that determine how well—or poorly—one's brain will age. She consults experts in the fields of sleep, stress, traumatic brain injury, hormones, genetics, and dementia, as well as specialists in nutrition, cognitive psychology, and the burgeoning field of drug-based cognitive enhancement. The landscape of the midlife brain is not what you might think, and to understand its strengths and weaknesses turns out to be the best way to cope.Jakobson Ramin's reporting of the stories of a wide array of midlife men and women will resonate with readers. Her audience will glean spectacular insight into how to elicit the very best performance from a middle-aged brain. A groundbreaking work that represents the best of narrative nonfiction, this is a timely, highly readable, and much-needed book for anyone whose memory is not what it used to be.

    Katherine Sharpe, the former editor of Seed magazine’s ScienceBlogs.com, addresses the questions that millions of young men and women are struggling with. “Where does my personality end and my prescription begin?” “Do I have a disease?” “Can I get better on my own?” Combining stout scientific acumen with first-person experience gained through her own struggle with antidepressants, Sharpe leads the reader through a complex subject, a guide towards a clearer future for all.

    This book includes a chapter on friendship for women with ADHD.

    The highs, the lows, historic match days and foul play. It’s a celebration of a beloved player, a history maker, and his tragic ending at the final whistle. It’s a story about science and discovery, about the people on the front line of life-changing research. But above all it’s a story about family and about consequence. All of this is wrapped up in three little letters: CTE. An investigative documentary from multi-award-winning producer Hana Walker-Brown [Audio Production Awards Best Documentary (Winner, 2017, 2016), Prix Europa (Nominee, 2018, 2017, 2015), Åke Blomström Prize (Winner, 2015) Hearsay International Audio Arts Award (Nominee, 2014) and Charles Parker Prize Gold Award (Winner, 2013)], The Beautiful Brain looks at the devastating effects of chronic traumatic encephalopathy (CTE) - a degenerative brain disease found in people who’ve suffered severe or repeated blows to the head. Beginning with the story of FA Cup winner Jeff Astle, the audiobook expands outwards looking at the widows, daughters and families who are left fighting for answers following the death of their loved ones. As the documentary progresses, Hana’s investigation leads her from Britain’s football pitches to support groups for victims of domestic violence and beyond, sparking a vital discussion about accountability and the urgent need for further scientific studies into CTE.Running time: 3 hrs and 42 mins©2019 Audible, Ltd (P)2019 Audible, Ltd

    Along the way, you’ll encounter Boschean beasts, giant squid, guitar-playing sea slugs, and the great pioneers of neuroscience. Hana Roš and Matteo Farinella provide an insight into the most complex thing in the universe.

    They speak their own language, they abide by their own rules, and they seem to exist to drive adults crazy. But adolescence is a typical stage of human development that is the essential preparation for success in the adult world. The more you understand about your teen’s brain, the better prepared you will be to handle this turbulent time in your child’s life.Professor Abigail Baird has devoted the majority of her career to studying adolescence, and in this Audible Original, she shares the latest perspectives on this amazing time of cognitive and behavioral growth. The 10 lectures in this series will reveal that adolescent behavior is much easier to understand than most people think. Rather than seeing the teen years as a crucible to be endured by parents and young people alike, this series offers a practical perspective for adults who hope to help teens truly thrive in their personal journeys to adulthood—not merely to survive their adolescence.Whether you are a parent, someone who works with teens, or even a teen yourself, this course will shed new light on a period of human development that is all too often incorrectly described as a time where psychological peril is inevitable.