Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

    In this extraordinary feat of nature writing, we meet ants who harvest crops, raise insects as livestock, build roadways and bridges, embark on nuptial flights, and make war.

    After a highly publicized and controversial exit from Mormonism, Lamborn intertwines the story of his awakening with psychological aspects of religious belief.

    Nature’s many innovations—some uncannily perfect—call for natural principles that accelerate life’s ability to innovate.”Darwin’s theory of natural selection explains how useful adaptations are preserved over time. But the biggest mystery about evolution eluded him. As genetics pioneer Hugo de Vries put it, “natural selection may explain the survival of the fittest, but it cannot explain the arrival of the fittest.”Can random mutations over a mere 3.8 billion years really be responsible for wings, eyeballs, knees, camouflage, lactose digestion, photosynthesis, and the rest of nature’s creative marvels? And if the answer is no, what is the mechanism that explains evolution’s speed and efficiency?In Arrival of the Fittest, renowned evolutionary biologist Andreas Wagner draws on over fifteen years of research to present the missing piece in Darwin's theory. Using experimental and computational technologies that were heretofore unimagined, he has found that adaptations are not just driven by chance, but by a set of laws that allow nature to discover new molecules and mechanisms in a fraction of the time that random variation would take.Consider the Arctic cod, a fish that lives and thrives within six degrees of the North Pole, in waters that regularly fall below 0 degrees. At that temperature, the internal fluids of most organisms turn into ice crystals. And yet, the arctic cod survives by producing proteins that lower the freezing temperature of its body fluids, much like antifreeze does for a car’s engine coolant. The invention of those proteins is an archetypal example of nature’s enormous powers of creativity. Meticulously researched, carefully argued, evocatively written, and full of fascinating examples from the animal kingdom, Arrival of the Fittest offers up the final puzzle piece in the mystery of life’s rich diversity.

    Spanning evolutionary science from its inception to its latest findings, from discoveries and data to philosophy and history, this book is an authoritative introduction to evolutionary biology.

    Olga Kotelko is not your average ninety-three-year-old. She not only looks and acts like a much younger woman, she holds over twenty-three world records in track and field, seventeen in her current ninety to ninety-five category. Convinced that this remarkable woman could help unlock many of the mysteries of aging, Grierson set out to uncover what it is that’s driving Olga. He considers every piece of the puzzle, from her diet and sleep habits to how she scores on various personality traits, from what she does in her spare time to her family history. Olga participates in tests administered by some of the world’s leading scientists and offers her DNA to groundbreaking research trials. What emerges is not only a tremendously uplifting personal story but a look at the extent to which our health and longevity are determined by the DNA we inherit at birth, and the extent to which we can shape that inheritance. It examines the sum of our genes, opportunities, and choices, and the factors that forge the course of any life, especially during our golden years.

    This updated edition features new material.

    Readers who enjoyed Too Much Tuscan Sun will welcome this second book, which includes even more episodes from the author’s life growing up as a Chiantigiano.

    Have you ever stopped to think about what it is that will make your life worth living? Is it the large amount of money that you have in the bank? The prestigious education that you have? The family and friends that surround you? Or your spiritual belief that there is someone greater than you in the world? Most people will spend their entire lifetimes trying to figure it out, but only a few will have the privilege of really understanding and experiencing themselves what it means to live a fulfilled life. Over the past years, we’ve seen many life philosophies take center stage, all claiming to hold to secret to happiness and fulfillment. While all of them may have very convincing premises, only one truly stands out. Ikigai, or the Japanese concept of finding your purpose, is the key to living a meaningful life. If there’s one people group who have mastered the art of living - and living well, it’s definitely the Okinawans of Japan. Famous for being the world’s longest-living people, they attribute their joy and contentment to finding their ikigai. It’s the reason why they live longer, happier, and better lives than the rest of us. So how does knowing your ikigai change your life? And what should you do to help you uncover your ikigai? Well, you’ll discover all that and more after you’ve listened to this audiobook. This audiobook is packed with helpful insights that will change not just the way you think, but also the way you live. You’ll learn how to slow down and let go of the things that stop you from finding your ultimate purpose. This audiobook will also give you the blueprint to living the life that you always wanted so you won’t have to feel your life is meaningless ever again. I hope that through this audiobook, you will see joy, meaning, and purpose in every single day of your life.©2018 Zen Mastery (P)2018 Zen Mastery

    In an era when women were rarely permitted any serious schooling, this twenty-seven-year-old’s nimble conversation and unusual brilliance led Voltaire, then in his late thirties, to wonder, “Why did you only reach me so late?” They fell immediately and passionately in love.Through the prism of their tumultuous fifteen-year relationship we see the crumbling of an ancient social order and the birth of the Enlightenment. Together the two lovers rebuilt a dilapidated and isolated rural chateau at Cirey where they conducted scientific experiments, entertained many of the leading thinkers of the burgeoning scientific revolution, and developed radical ideas about the monarchy, the nature of free will, the subordination of women, and the separation of church and state. But their time together was filled with far more than reading and intellectual conversation. There were frantic gallopings across France, sword fights in front of besieged German fortresses, and a deadly burning of Voltaire’s books by the public executioner at the base of the grand stairwell of the Palais de Justice in Paris. The pair survived court intrigues at Versailles, narrow escapes from agents of the king, a covert mission to the idyllic lakeside retreat of Frederick the Great of Prussia, forays to the royal gambling tables (where Emilie put her mathematical acumen to lucrative use), and intense affairs that bent but did not break their bond.Along with its riveting portrait of Voltaire as a vulnerable romantic, Passionate Minds at last does justice to the supremely unconventional life and remarkable achievements of Emilie du Châtelet—including her work on the science of fire and the nature of light. Long overlooked, her story tells us much about women’s lives at the time of the Enlightenment. Equally important, it demonstrates how this graceful, quick-witted, and attractive woman worked out the concepts that would lead directly to the “squared” part of Einstein’s revolutionary equation: E=mc2.Based on a rich array of personal letters, as well as writings from houseguests, neighbors, scientists, and even police reports, Passionate Minds is both panoramic and intimate in feeling. It is an unforgettable love story and a vivid rendering of the birth of modern ideas.

    This Hockey Dad, Bob McKenzie, is not afraid to look into the mirror and candidly assess and reveal his own strengths and weaknesses. He has anecdotes that will make you laugh, stories that will bring a tear to your eye, and insights into this minor hockey world that can only come from having lived through the highs and the lows and everything in between with two boys who grew up in an environment where minor hockey was their epicenter. Michael is now a 22-year-old entering his junior year playing NCAA hockey on scholarship, one step away from the professional ranks. Shawn, now 19, had his competitive minor hockey life cut drastically short at age 14 because of complications from multiple concussions. While Michael has attempted to, and continues to try to, scale the heights within hockey, Shawn has, at times, had to navigate the depths. Their deeply personal stories, and how their father dealt with them (sometimes well, sometimes not so well), are a compelling look into the world of minor hockey--a major Canadian passion. From hysterically funny anecdotes, to debates on numerous hockey issues, praise and criticism for the system, and personal reflections on the game, this book is an insightful, irreverent, and moving look at a slice of hockey culture that is not so much a recreation as it is a way of life.

    Who else routinely interviews the likes of Lynn Margulis, Roger Penrose, Francis Crick, Richard Dawkins, Freeman Dyson, Murray Gell-Mann, Stephen Jay Gould, Stephen Hawking, Thomas Kuhn, Chris Langton, Karl Popper, Stephen Weinberg, and E.O. Wilson, with the freedom to probe their innermost thoughts?In The End Of Science, Horgan displays his genius for getting these larger-than-life figures to be simply human, and scientists, he writes, ”are rarely so human...so at ther mercy of their fears and desires, as when they are confronting the limits of knowledge.”This is the secret fear that Horgan pursues throughout this remarkable book: Have the big questions all been answered? Has all the knowledge worth pursuing become known? Will there be a final ”theory of everything” that signals the end? Is the age of great discoverers behind us? Is science today reduced to mere puzzle solving and adding detains to existing theories?Horgan extracts surprisingly candid answers to there and other delicate questions as he discusses God, Star Trek, superstrings, quarks, plectics, consciousness, Neural Darwinism, Marx's view of progress, Kuhn's view of revolutions, cellular automata, robots, and the Omega Point, with Fred Hoyle, Noam Chomsky, John Wheeler, Clifford Geertz, and dozens of other eminent scholars. The resulting narrative will both infuriate and delight as it mindles Horgan's smart, contrarian argument for ”endism” with a witty, thoughtful, even profound overview of the entire scientific enterprise.Scientists have always set themselves apart from other scholars in the belief that they do not construct the truth, they discover it. Their work is not interpretation but simple revelation of what exists in the empirical universe. But science itself keeps imposing limits on its own power. Special relativity prohibits the transmission of matter or information as speeds faster than that of light; quantum mechanics dictates uncertainty; and chaos theory confirms the impossibility of complete prediction. Meanwhile, the very idea of scientific rationality is under fire from Neo-Luddites, animal-rights acitivists, religious fundamentalists, and New Agers alike.As Horgan makes clear, perhaps the greatest threat to science may come from losing its special place in the hierarchy of disciplines, being reduced to something more akin to literaty criticism as more and more theoreticians engage in the theory twiddling he calls ”ironic science.” Still, while Horgan offers his critique, grounded in the thinking of the world's leading researchers, he offers homage too. If science is ending, he maintains, it is only because it has done its work so well.

    Table of Contents General Information Vol I Diversity in the Living World Structural Organisation in Plants and Animals Cell Structure and Function Plant Physiology Human Physiology Vol II Reproduction Genetics and Evolution Biology and Human Welfare Biotechnology and Its Applications Ecology and Environment Some More Additional Topics Assertion and Research Questions top

    Yet there is much more to the monarch than its distinctive presence and mythic journeying. In Monarchs and Milkweed, Anurag Agrawal presents a vivid investigation into how the monarch butterfly has evolved closely alongside the milkweed--a toxic plant named for the sticky white substance emitted when its leaves are damaged--and how this inextricable and intimate relationship has been like an arms race over the millennia, a battle of exploitation and defense between two fascinating species.The monarch life cycle begins each spring when it deposits eggs on milkweed leaves. But this dependency of monarchs on milkweeds as food is not reciprocated, and milkweeds do all they can to poison or thwart the young monarchs. Agrawal delves into major scientific discoveries, including his own pioneering research, and traces how plant poisons have not only shaped monarch-milkweed interactions but have also been culturally important for centuries. Agrawal presents current ideas regarding the recent decline in monarch populations, including habitat destruction, increased winter storms, and lack of milkweed--the last one a theory that the author rejects. He evaluates the current sustainability of monarchs and reveals a novel explanation for their plummeting numbers.Lavishly illustrated with more than eighty color photos and images, Monarchs and Milkweed takes readers on an unforgettable exploration of one of nature's most important and sophisticated evolutionary relationships.

    From the unforgettable moment when a wild chimpanzee gently grasps her hand to the terror of a hostage-taking and the sorrow of her husband's death. Here, thoughtfully exploring the challenges of both science and the soul, she offers an inspiring, optimistic message as profound as the knowledge she brought back from the forests, and that gives us all...reason for hope.