This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions - 98% of the human genome - were dismissed as 'junk'. But in recent years researchers have discovered that variations in this 'junk' DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself - and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.

    In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today. Whipsawed by daily crises and frustrations, Reilly must deal with several daunting challenges simultaneously: the extraordinary patients under his care on the teeming wards of a renowned teaching hospital; the life-threatening illnesses of both of his ninety-year-old parents; and the tragic memory of a cold case from long ago that haunts him still. As Reilly’s patients and their families survive close calls, struggle with heartrending decisions, and confront the limits of medicine’s power to cure, One Doctor lays bare a fragmented, depersonalized, business-driven health-care system where real caring is hard to find. Every day, Reilly sees patients who fall through the cracks and suffer harm because they lack one doctor who knows them well and relentlessly advocates for their best interests.Filled with fascinating characters in New York City and rural New England — people with dark secrets, mysterious illnesses, impossible dreams, and many kinds of courage — One Doctor tells their stories with sensitivity and empathy, reminding us of professional values once held dear by all physicians. But medicine has changed enormously during Reilly’s career, for both better and worse, and One Doctor is a cautionary tale about those changes. It is also a hopeful, inspiring account of medicine’s potential to improve people’s lives, Reilly’s quest to understand the "truth" about doctoring, and a moving testament to the difference one doctor can make.

    Though referenced like a work of research, Brizedine's writing style is fully accessible. Brizendine provides a fascinating look at the life cycle of the female brain from birth ("baby girls will connect emotionally in ways that baby boys don't") to birthing ("Motherhood changes you because it literally alters a woman's brain-structurally, functionally, and in many ways, irreversibly") to menopause (when "the female brain is nowhere near ready to retire") and beyond. At the same time, Brizedine is not above reviewing the basics: "We may think we're a lot more sophisticated than Fred or Wilma Flintstone, but our basic mental outlook and equipment are the same." While this book will be of interest to anyone who wonders why men and women are so different, it will be particularly useful for women and parents of girls.

    Part One presents the general principles of pathophysiology and discusses the influence of the environment and the role of genetics in the development of disease. Part Two, organized by body system, examines normal anatomy and physiology, alterations of function in adults, and alterations of function in children.

    Charting the most cutting-edge scientific breakthroughs, and marshalling his decades of research and clinical practice, Walker explains how we can harness sleep to improve learning, mood and energy levels, regulate hormones, prevent cancer, Alzheimer's and diabetes, slow the effects of aging, and increase longevity. He also provides actionable steps towards getting a better night's sleep every night.

    His theories on the evolutionary tensions between parent and offspring, sibling and sibling, man and woman, friend and friend, and a person and himself or herself have not only revolutionized genetics and evolutionary biology but have influenced disciplines from medicine and the social sciences to history, economics, and literary studies. But unlike other renowned scientists, Trivers has spent time behind bars, drove a getaway car for Huey P. Newton, and founded an armed group in Jamaica to protect gay men from mob violence. Now, in the entertaining tradition of Surely You're Joking Mr. Feynman, Trivers tell us in his inimitable voice about the inimitable life behind the revolutionary science. He comments with irreverent wit and penetrating insight on everything from American racism to the history of psychiatry to who killed Peter Tosh, musical heir to Bob Marley. Sprinkled with anecdotes about such luminaries as Richard Dawkins and Stephen Jay Gould, and with photographs throughout, this volume is sure to enlighten and entertain anyone with an interest in science, the human condition, or the nature of creative genius. PRAISE FOR WILD LIFE"To call Robert Trivers an acclaimed biologist is an understatement akin to calling the late Richard Feynman a popular professor of physics." -- PSYCHOLOGY TODAY"Who would have guessed that arguably today’s most original thinker in evolutionary theory could possibly have led the extraordinary life Robert Trivers recounts in these pages. We are taken on a wild trip from inspired meditations on the biology of self deception, through a steamy Jamaican underworld, to Black Panthers in California, to frank appraisals of distinguished or over-rated scientists, the whole adding up to a disarmingly frank and utterly unique memoir of a rollercoaster of a life. -- RICHARD DAWKINS, bestselling author of The Selfish Gene and The God Delusion“Robert Trivers is not just a brilliant evolutionary thinker but a world-class raconteur, adventurer, kibitzer, people-watcher, jester, and provocateur. This memoir is filled with sharp and hilarious observations about the living world, not least a certain species of hairless primate, not least a certain member of that species named Robert Trivers.” – STEVEN PINKER,best-selling author of How the Mind Works and The Better Angels of Our Nature: Why Violence Has Declined“It would not be hyperbole to say that Robert Trivers is one of the most important evolutionary theorists since Charles Darwin. But contrary to the image most people have of theoretical scientists as stodgy intellectuals holed up in their offices buried in paper, Trivers' memoir reveals a man whose life has been wild in every sense of the word. A lust for life doesn’t begin to sum up a career devoted to truth, courage, and the audacity to think what no one else has thought, and to act in ways few others would dare (you’ll even learn how to defend yourself in a knife fight). If that were not enough, Trivers is witty, clever, and compassionate. This book is destined to become a classic in scientific autobiography." -- MICHAEL SHERMER, Editor in Chief, The SkepticABOUT THE AUTHORRobert Trivers is a professor of anthropology and biological sciences at Rutgers University.

    Susan Macqueen was 12 years old when she accompanied her mother to see her friend Ms. Fairweather, the matron at the local nursing home, and from that day on she knew she wanted to be a nurse. A few years later, despite being told that her grades weren't good enough, Susan was accepted on the three-year nurses training course at Addenbooke's hospital in Cambridge. It wasn't long before Susan knew she wanted to work with children and set her sights on a job at Great Ormond Street. Thirty-five years later, on her third attempt, Susan has finally retired from that iconic hospital and is enjoying a more leisurely pace of life. Hope, despair, laughter, and tears, Susan's stories move the reader through the incredible stories that she was faced with on an every day basis.

    This is the complete novel version--no cliffhangers. Billionaires don’t date real women like Jada ... they marry them. Jada Howarth doesn’t believe in fantasies, unlike her sister who dreams of being swept into happily-ever-after in the sculpted arms of a handsome billionaire. Jada knows the truth, that rich men want supermodels, actresses and heiresses. They don’t want women from small towns with smaller bank accounts, women who lead normal, ordinary lives like Jada. Then the day arrives when Jada awakes to find a swarm of reporters outside her house. They want the scoop on her secret marriage to Ian Buckley, one of the wealthiest, most sought-after bachelors in the country. Jada is dumbfounded. She has no idea what they’re talking about, but no one’s listening to her. Ian Buckley, billionaire and man-in-charge, couldn’t be more surprised when he’s told that a marriage license was leaked to the press proving he married someone named Jada Howarth. He’s never heard of her, and he definitely doesn’t remember marrying her. Either he’s lost his wits, or someone’s out to make a fool of him. When Ian sees the disheveled, lovely Jada on TV, peeking out her door in horror at the press crushing her lawn, he’s confident she’s not behind the scam. He’ll have to meet her to be certain. Men should probably meet their wives, anyway, shouldn’t they? It’ll be fun getting to the bottom of this fiasco. Whodunnit? Perhaps spending time with his bride at Ian’s lakeside estate will solve the mystery.

    

    recreates verbal images of the events surrounding the Advent of Christ, offering a devotional journey into the heart of the Christmas season. Through rich detail and vivid images, these moving meditations make Christ's birth both intimate and immediate, allowing us to see Christmas from its original happening to its perennial recurrence in our hearts. Preparing for Jesus is sure to be a seasonal classic, treasured year after year.

    Conventional wisdom may be wrong. In this controversial book, the eminent biologist Paul W. Ewald offers some startling arguments:-Germs appear to be at the root of heart disease, Alzheimer’s, schizophrenia, many forms of cancer, and other chronic diseases.-The greatest threats to our health come not from sensational killers such as Ebola, West Nile virus, and super-virulent strains of influenza, but from agents that are already here causing long-term infections, which eventually lead to debilitation and death. -The medical establishment has largely ignored the evidence that implicates these germs, to the detriment of our public health.-New evolutionary theories are available, which explain how germs function and offer opportunities for controlling these modern plagues — if we are willing to listen to them.Plague Time is an eye-opening exploration of the revolutionary new understanding of disease that may set the course of medical research for the twenty-first century.

    It is uniquely designed to help students master pharmacology both in class and in preparing for the NCLEX(R) examination. It will also benefit practicing nurses who'd like a refresher and memory device on pharmacology. Using a wide variety of learning aids, humor, illustrations, and mnemonics, it covers topics including administration, antibiotics, antivirals, anticoagulants, cardiac drugs, CNS drugs, diuretics, endocrine drugs, GI drugs, musculoskeletal drugs, OB drugs, pain, psychiatric drugs, and pulmonary drugs.Features 91 full-color illustrated mnemonics on individual drug topics and key drugs.Offers durability and portability with spiral-bound format and removable cards on sturdy stock.Perforated cards may be used as is, in spiral-bound notebook or removed for use as individual flash cards, which allows the reader flexibility when studying.Topics are listed alphabetically for quick reference.Offers easy referral, with tabs and color cover guide using a different color for each topic.Concise What You Need to Know drug monographs on the back of each image include quick information on drug action, use, contraindications/precautions, side effects, and nursing implications.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.