Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. Theimmune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called innate immuneresponses, which react very fast to infection, and adaptive immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading toserious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the Immunesystem v2.o - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

    Despite this, and perhaps in part because of its prevalence in the media, it is often denigrated as trivial and superficial, as a sign of vanity and narcissism. Written by a highly regarded authority on twentieth-century fashion, this Very Short Introduction offer a wide-ranging and revealing look at fashion that discusses everything from production and design, to couture and retailing, to the wider role of fashion in society. This lively book illuminates the structure of the fashion industry and the range of professionals involved in its creation, and it provides cogent insight into its historical, social and cultural contexts. It also sheds light on how fashion has developed, while raising questions about its ethical and controversial aspects, such as the use of fur, exploitative trading, and poor working conditions for laborers.

    S. Lewis claimed, or is it part of human nature? Will winning the lottery really make you happy? Is it possible to build robots that have feelings? These are just some of the intriguing questions explored in this new guide to the latest thinking about emotions. Drawing on a wide range of scientific research, from anthropology and psychology to neuroscience and artificial intelligence, Emotion: The Science of Sentiment takes the reader on a fascinating journey into the human heart. Illustrating his points with entertaining examples from fiction, film, and popular culture, Dylan Evans ranges from the evolution of emotions to the nature of love and happiness to the language of feelings, offering readers the most recent thinking on real life topics that touch us all.

    It tackles many questions, such as: What accounts for the perpetuation of ethnic and religious conflict in Ireland? Why has armedviolence proven so hard to control? Who are the major figures and issues in the conflict? Can we expect more Northern Irelands in the future?

    In this Very Short Introduction, engineer David Muir Wood turns a spotlight on a field that we often take for granted. He sheds light on the nature and importance of civil engineering in the history of civilization and urbanization, outlines its many accomplishments in the modern era, and points to the hurdles that civil engineering will face in the future. Beginning with the task of creating a settlement on a deserted island, Muir Wood sets out the problems that civil engineers face every day, highlighting the social and environmental challenges as well as the grasp of science and technology needed to craft buildings, bridges, tunnels, houses, and areas of recreation. The author also profiles the lives of some of the major civil engineers, such as Isambard Kingdom Brunel, the acclaimed builder of steamships, railways, and tunnels, and Sir Joseph Bazalgette, whose sewer system in central London was instrumental in relieving the city from cholera epidemics. Finally, Muir Wood considers the growing difficulty of managing our water and energy supplies, and he looks at the engineering profession's increased sensitivity to building and the environment.

    People readily behave as amateur psychologists, offering explanations for what we think, feel, and do. But what exactly are psychologists trying to help us understand? What scientific grounding do they have for their approach? In Psychology: A Very Short Introduction, Dr. Gillian Butler and Dr. Freda McManus provide an understanding of some of psychology's leading ideas and their practical relevance. The authors answer some of the most frequently asked questions about psychology including: What is psychology? How do we use what is in the mind? How does psychology work? How do we influence each other? What can or can't a psychologist do for you? Psychology is a large part of our everyday experience, and this elemental guide is a stimulating introduction for anyone interested in understanding the human mind. About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

    In its heyday during the late 1990s, neoliberalism emerged as the world's dominant economic paradigm, stretching from the Anglo-American heartlands of capitalism to the former communist bloc all the way to the developing regions of the global South. Today, however, neoliberalism has been discredited as the global economy, built on its principles, has been shaken to its core by the worst financial calamity since the 1930s. Is neoliberalism doomed or will it regain its former status? Will the new U.S. President Barack Obama embrace or reject the neoliberal agenda of his predecessors in the White House? And how will his decision impact the current global economic order? Is there a viable alternative to neoliberalism? Exploring the origins, core claims, and various forms of neoliberalism, this Very Short Introduction offers a concise and accessible introduction to one of the most debated "isms" of our time.

    The rise of the Internet and the wide availability of inexpensive computers have made it possible to gather and analyze network data on a large scale, and the development of a variety of new theoretical tools has allowed us to extract new knowledge from many different kinds of networks.The study of networks is broadly interdisciplinary and important developments have occurred in many fields, including mathematics, physics, computer and information sciences, biology, and the social sciences. This book brings together for the first time the most important breakthroughs in each of these fields and presents them in a coherent fashion, highlighting the strong interconnections between work in different areas.Subjects covered include the measurement and structure of networks in many branches of science, methods for analyzing network data, including methods developed in physics, statistics, and sociology, the fundamentals of graph theory, computer algorithms, and spectral methods, mathematical models of networks, including random graph models and generative models, and theories of dynamical processes taking place on networks.

    It traces the history and cultural impact of the elements on humankind, and examines why people have long sought to identify thesubstances around them. The book includes chapters on particular elements such as gold, iron, and oxygen, showing how they shaped culture and technology. Looking beyond the Periodic Table, the author examines our relationship with matter, from the uncomplicated vision of the Greek philosophers, whobelieved there were four elements--earth, air, fire, and water--to the work of modern-day scientists in creating elements such as hassium and meitnerium. Packed with anecdotes, The Elements is a highly engaging and entertaining exploration of the fundamental question: what is the world made from?

    Arguments still rage about the implications of his evolutionary theory, and scepticism about the value of Darwin's contribution to knowledge is widespread. In this analysis of Darwin's major insights and arguments, Jonathan Howard reasserts the importance of Darwin's work for the development of modern science and culture."--BOOK JACKET.

    It offers a compelling account of the political, religious and economic changes of the country under such leading monarchs as Henry VIII and Elizabeth I.The work has been substantially revised and updated for this edition. In particular, the reigns of Henry VII, Edward VI, and Philip and Mary are comprehensively reassessed.

    In this Very Short Introduction, Michael Newman seeks to place the idea of socialism in a modern context for today's readers. He explains socialist ideas in the framework of its historical evolution, from the French Revolution to the present day, and examines practical attempts to implement socialism.Not just another history of socialist ideas, this book aims for a different approach that looks at practice as well as theory--centering on the contrast between Communism and Social Democracy. The relationship between socialism and notions of democracy, freedom, and equality is also discussed. Newman brings the subject entirely up to date by tackling contemporary forms of socialism. While the book's focus is on Europe and the Soviet Union, it is set in a broader geographical context. Newman's fresh approach to the subject enables the reader to re-evaluate socialism.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

    It draws on material from the recent report of the Intergovernmental Panel on Climate Change, a huge collaborative study drawing together current thinking on the subject from experts in a range of disciplines, and presents the findings of the panel for a general readership for the first time. The book also discusses the politics of global warming and what we can do now to adapt to climate change and mitigate its worst effects.

    Writing with a focus on Christianity, David Ford provides a trenchant and balanced discussion of the study of faith and religion. He describes the development of the field of theology, and explores such issues as knowledge, community, worship, salvation, God, prayer, and evil. Ford also weaves the idea of the quest for wisdom into the entire fabric of his discussion, and concludes with a look ahead to the theology of the next century. Theology: A Very Short Introduction tackles the questions raised by and about religion in a thought-provoking and engaging manner. About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

    Yet there is much more to the debate than theclash of these extremes. As Thomas Dixon shows in this balanced and thought-provoking introduction, a whole range of views, subtle arguments, and fascinating perspectives can be found on this complex and centuries-old subject. He explores the key philosophical questions that underlie the debate, but also highlights the social, political, and ethical contexts that have made the tensions between science and religion such a fraught and interesting topic in the modern world. Dixon emphasizes how the modern conflict between evolution and creationism is quintessentially an American phenomenon, arising from the culture and history of the United States, as exemplified through the ongoing debates about how to interpret the First-Amendment's separation of church and state. Along the way, he examines landmark historical episodes such as the Galileo affair, Charles Darwin's own religious andscientific odyssey, the Scopes Monkey Trial in Tennessee in 1925, and the Dover Area School Board case of 2005, and includes perspectives from non-Christian religions and examples from across the physical, biological, and social sciences.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundredsof key topics, from philosophy to Freud, quantum theory to Islam.