The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race
Walter Isaacson - 2021
As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.
Elizabeth the Queen: The Life of a Modern Monarch
Sally Bedell Smith - 2012
But through the fog of glamour and gossip, how well do we really know the world’s most famous monarch? Drawing on numerous interviews and never-before-revealed documents, acclaimed biographer Sally Bedell Smith pulls back the curtain to show in intimate detail the public and private lives of Queen Elizabeth II, who has led her country and Commonwealth through the wars and upheavals of the last sixty years with unparalleled composure, intelligence, and grace. In Elizabeth the Queen, we meet the young girl who suddenly becomes “heiress presumptive” when her uncle abdicates the throne. We meet the thirteen-year-old Lilibet as she falls in love with a young navy cadet named Philip and becomes determined to marry him, even though her parents prefer wealthier English aristocrats. We see the teenage Lilibet repairing army trucks during World War II and standing with Winston Churchill on the balcony of Buckingham Palace on V-E Day. We see the young Queen struggling to balance the demands of her job with her role as the mother of two young children. Sally Bedell Smith brings us inside the palace doors and into the Queen’s daily routines—the “red boxes” of documents she reviews each day, the weekly meetings she has had with twelve prime ministers, her physically demanding tours abroad, and the constant scrutiny of the press—as well as her personal relationships: with Prince Philip, her husband of sixty-four years and the love of her life; her children and their often-disastrous marriages; her grandchildren and friends.
A Very Expensive Poison: The Definitive Story of the Murder of Litvinenko and Russia's War with the West
Luke Harding - 2016
Alexander Litvinenko is brazenly poisoned in central London. Twenty two days later he dies, killed from the inside. The poison? Polonium; a rare, lethal and highly radioactive substance. His crime? He had made some powerful enemies in Russia.Based on the best part of a decade's reporting, as well as extensive interviews with those closest to the events (including the murder suspects), and access to trial evidence, Luke Harding's A Very Expensive Poison is the definitive inside story of the life and death of Alexander Litvinenko. Harding traces the journey of the nuclear poison across London, from hotel room to nightclub, assassin to victim; it is a deadly trail that seemingly leads back to the Russian state itself.Harding argues that Litvinenko's assassination marked the beginning of the deterioration of Moscow's relations with the west and a decade of geo-political disruptions--from the war in Ukraine, a civilian plane shot down, at least 7,000 dead, two million people displaced and a Russian president's defiant rejection of a law-based international order. With Russia's covert war in Ukraine and annexation of the Crimea, Europe and the US face a new Cold War, but with fewer certainties.This is a shocking real-life revenge tragedy with corruption and subterfuge at every turn, and walk-on parts from Russian mafia, the KGB, MI6 agents, dedicated British coppers, Russian dissidents. At the heart of this all is an individual and his family torn apart by a ruthless crime.
Bad Sports: How Owners Are Ruining the Games We Love
Dave Zirin - 2010
Complaints abound: from inflated ticket prices, $6 hot dogs, and $9 beers to owners endlessly demanding new multimillion-dollar stadiums funded by public tax dollars. Those sitting in the owners’ boxes are increasingly placing profit over players’ performances and fan loyalty. Bad Sports cuts through the hype and bombast to zero in on tales of abusive, dictatorial owners who move their teams thousands of miles away from their fan base, use their stadiums as religious and political platforms, or hold communities ransom for millions of dollars of taxpayer money to fund their gargantuan stadiums.As the multibillion-dollar sports-industrial complex continues to lumber along, Dave Zirin is the voice in the wilderness, speaking out for the common fan with a tough, passionate, and intelligent voice that will remind readers that there is more to sportswriting than glowing athlete profiles.
The Black Count: Glory, Revolution, Betrayal, and the Real Count of Monte Cristo
Tom Reiss - 2012
The real-life protagonist of The Black Count, General Alex Dumas, is a man almost unknown today yet with a story that is strikingly familiar, because his son, the novelist Alexandre Dumas, used it to create some of the best loved heroes of literature.Yet, hidden behind these swashbuckling adventures was an even more incredible secret: the real hero was the son of a black slave -- who rose higher in the white world than any man of his race would before our own time. Born in Saint-Domingue (now Haiti), Alex Dumas was briefly sold into bondage but made his way to Paris where he was schooled as a sword-fighting member of the French aristocracy. Enlisting as a private, he rose to command armies at the height of the Revolution in an audacious campaign across Europe and the Middle East – until he met an implacable enemy he could not defeat.The Black Count is simultaneously a riveting adventure story, a lushly textured evocation of 18th-century France, and a window into the modern world’s first multi-racial society. But it is also a heartbreaking story of the enduring bonds of love between a father and son.
And the Sun Shines Now: How Hillsborough and the Premier League Changed Britain
Adrian Tempany - 2014
The Hillsborough disaster was broadcast live on the BBC; it left millions of people traumatised, and English football in ruins.And the Sun Shines Now is not a book about Hillsborough. It is a book about what arrived in the wake of unquestionably the most controversial tragedy in the post-war era of Britain's history. The Taylor Report. Italia 90. Gazza's tears. All seater stadia. Murdoch. Sky. Nick Hornby. The Premier League. The transformation of a game that once connected club to community to individual into a global business so rapacious the true fans have been forgotten, disenfranchised.In powerful polemical prose, against a backbone of rigorous research and interviews, Adrian Tempany deconstructs the past quarter century of English football and examines its place in the world. How did Hillsborough and the death of 96 Liverpool fans come to change the national game beyond recognition? And is there any hope that clubs can reconnect with a new generation of fans when you consider the startling statistic that the average age of season ticket holder here is 41, compared to Germany's 21?Perhaps the most honest account of the relationship between the football and the state yet written, And the Sun Shines Now is a brutal assessment of the modern game.
Back to Work: Why We Need Smart Government for a Strong Economy
Bill Clinton - 2011
He supports President Obama’s emphasis on green technology, saying that changing the way we produce and consume energy is the strategy most likely to spark a fast-growing economy while enhancing our national security.Clinton also stresses that we need a strong private sector and a smart government working together to restore prosperity and progress, demonstrating that whenever we’ve given in to the temptation to blame government for all our problems, we’ve lost our ability to produce sustained economic growth and shared prosperity.Clinton writes, “There is simply no evidence that we can succeed in the twenty-first century with an antigovernment strategy,” based on “a philosophy grounded in ‘you’re on your own’ rather than ‘we’re all in this together.’ ” He believes that conflict between government and the private sector has proved to be good politics but has produced bad policies, giving us a weak economy with not enough jobs, growing income inequality and poverty, and a decline in our competitive position. In the real world, cooperation works much better than conflict, and “Americans need victories in real life.”
Three Years in Hell: The Brexit Chronicles
Fintan O'Toole - 2020
In 2011 Queen Elizabeth made her first ever state visit to the Irish Republic. It was a great, moving occasion. 'In settling once and for all its relationship with Ireland,' Fintan O'Toole writes, 'Britain was also settling its relationship with the rest of the world taking its place as a normal, equal democracy.'
It was not to last.
Three Years in Hell is the fiercely intelligent, funny and sorrowful record of a slow-motion catastrophe. At its heart is the enigma of English nationalism. On the morning after the 2016 referendum O'Toole wrote:
'It is a question the English used to ask about their subject peoples: are they ready for self-government? But it is now one that has to be asked about the English themselves... England seems to be stumbling towards a national independence it has scarcely even discussed, let alone prepared for. It is on the brink of one of history's strangest nationalist revolutions.'
The story culminates in the election of Boris Johnson, running against a weak, accidental Labour leader who promised to remain 'neutral' on the most important question of our time.