The Structure of Scientific Revolutions is that kind of book. When it was first published in 1962, it was a landmark event in the history and philosophy of science. Fifty years later, it still has many lessons to teach. With The Structure of Scientific Revolutions, Kuhn challenged long-standing linear notions of scientific progress, arguing that transformative ideas don’t arise from the day-to-day, gradual process of experimentation and data accumulation but that the revolutions in science, those breakthrough moments that disrupt accepted thinking and offer unanticipated ideas, occur outside of “normal science,” as he called it. Though Kuhn was writing when physics ruled the sciences, his ideas on how scientific revolutions bring order to the anomalies that amass over time in research experiments are still instructive in our biotech age. This new edition of Kuhn’s essential work in the history of science includes an insightful introduction by Ian Hacking, which clarifies terms popularized by Kuhn, including paradigm and incommensurability, and applies Kuhn’s ideas to the science of today. Usefully keyed to the separate sections of the book, Hacking’s introduction provides important background information as well as a contemporary context.  Newly designed, with an expanded index, this edition will be eagerly welcomed by the next generation of readers seeking to understand the history of our perspectives on science.

    In this Very Short Introduction, renowned evolutionary scholar Bernard Wood traces the history of paleoanthropology from its beginnings inthe eighteenth century to today's latest fossil finds. Along the way we are introduced to the lively cast of characters, past and present, involved in evolutionary research. Although concentrating on the fossil evidence for human evolution, the book also covers the latest genetic evidence aboutregional variations in the modern human genome that relate to our evolutionary history. Wood draws on over thirty years of experience to provide an insiders view of the field, and demonstrates that our understanding of human evolution is critically dependent on advances in related sciences such aspaleoclimatology, geochronology, systematics, genetics, and developmental biology. This is an ideal introduction for anyone interested in the origins and development of humankind.

    This ninth edition covers both analytical and empirical approaches to the subject. The examples and templates provide students with resources for computer-numerical solutions.

    The sixth edition explores core concepts in considerable depth and presents experimental detail when it helps to explain and reinforce the concepts. The majority of discussions have been modified to reflect the latest changes in the field. The book also builds on its strong illustration program by opening each chapter with “VIP” art that serves as a visual summary for the chapter. Over 60 new micrographs and computer-derived images have been added to enhance the material. Biologists benefit from these changes as they build their skills in making the connection. Doody Review Services Reviewer: Bruce A. Fenderson, PhD(Thomas Jefferson University) Description: The author expertly organizes, explains, and illustrates the chemical and cellular basis of life on Earth in this comprehensive and exciting introduction to cell and molecular biology. The 18 fascinating chapters cover topics ranging from control of gene expression to mechanisms of immune response. There is even a chapter on laboratory techniques. The focus of the book is on biological chemistry, with an emphasis on core concepts and experimental approaches. Purpose: The purpose is to provide a textbook for an introductory course in cell and molecular biology. The author hopes that students will visualize a world filled with "giant molecules and minuscule structures" that constitute the chemistry of life. He encourages students to consider the evidence that is presented to support a biological model, think of alternate explanations, and plan experiments that may lead to new hypotheses. One of the author's goals is to help students develop their independent, critical-thinking skills. Audience: This is an excellent companion textbook for undergraduate and graduate-level courses in cell and molecular biology. It is written for students across a wide range of life science disciplines

    Today, that taboo is dead. The causal revolution, instigated by Judea Pearl and his colleagues, has cut through a century of confusion and established causality -- the study of cause and effect -- on a firm scientific basis. His work explains how we can know easy things, like whether it was rain or a sprinkler that made a sidewalk wet; and how to answer hard questions, like whether a drug cured an illness. Pearl's work enables us to know not just whether one thing causes another: it lets us explore the world that is and the worlds that could have been. It shows us the essence of human thought and key to artificial intelligence. Anyone who wants to understand either needs The Book of Why.

    The material is presented in a brief and quick-access format which allows for topic and exam review. It provides enough detailed and specific information to address most all questions and problems that arise in the ICU. Emphasis on fundamental principles in the text should prove useful for patient care outside the ICU as well.New chapters in this edition include hyperthermia and hypothermia syndromes; infection control in the ICU; and severe airflow obstruction. Sections have been reorganized and consolidated when appropriate to reinforce concepts.Purchase The ICU Book, Third Edition and visit TheICUBook.com, which gives you free access to links from references to PubMed, updated regularly; and a directory of Websites handpicked by Dr. Marino.

    This book draws on material Michael created for his renowned Object Mentor seminars, techniques Michael has used in mentoring to help hundreds of developers, technical managers, and testers bring their legacy systems under control. The topics covered include: Understanding the mechanics of software change, adding features, fixing bugs, improving design, optimizing performance Getting legacy code into a test harness Writing tests that protect you against introducing new problems Techniques that can be used with any language or platform, with examples in Java, C++, C, and C# Accurately identifying where code changes need to be made Coping with legacy systems that aren't object-oriented Handling applications that don't seem to have any structureThis book also includes a catalog of twenty-four dependency-breaking techniques that help you work with program elements in isolation and make safer changes.

    In this exciting book, we meet a who's who of heartless murderers. Mary Ann Cotton, who used arsenic to murder her mother, three husbands, a lover, eight of her own children, and seven step children; Michael Swango, who may have killed as many as 60 of his patients and several of his colleagues during the 20 years he practiced as a doctor and paramedic; and even Saddam Hussein, who used thallium sulfate to poison his political rivals. Emsley also shows which toxic elements may have been behind the madness of King George III, the delusions of Isaac Newton, and the strange death of King Charles II. In addition, the book examines many modern day environmental catastrophes, including accidental mass poisonings from lead and arsenic, and the Minamata Bay disaster in Japan. Written by a leading science writer, famous for his knowledge of the elements and their curious and colorful histories, The Elements of Murder offers an enticing combination of true crime tales and curious science that adds up to an addictive read.

    All chapters have been thoroughly updated with the latest information as well as new case studies, practice questions, and exercises. This latest edition not only covers the how of clinical testing but also places greater emphasis on the what, why, and when in order to meet the needs of today's clinical laboratorians. A companion Website offers the full text online, objectives, a quiz bank, flashcards, glossary, and appendices for students and improved instructor's resources.

    Its organization and thoroughness are unsurpassed, putting it above similar review books. Students who thoroughly read this book should have no trouble successfully completing their psychiatry clerkship and passing the shelf exam. As course director for the core psychiatry clerkship at my institution, I will recommend this book to students."--Doody's Review Service"First Aid for the Psychiatry Clerkship" gives you the core information needed to impress on the wards and pass the psychiatry clerkship exam. Written by students who know what it takes to succeed, and based on the national guidelines for the psychiatry clerkship, the book is filled with mnemonics, ward and exam tips, tables, clinical images, algorithms, and newly added mini-cases.Features Completely revised based on the psychiatry clerkship's core competencies Written by medical students who passed and reviewed by faculty for accuracy NEW integrated mini-cases illustrate classic patient presentations and/or commonly tested scenarios NEW illustrations and management algorithms Updated throughout with enhanced sections on medications, depression/anxiety, and child psychiatry Helps students hone in on the most important concepts for the clerkship and the examThe content you need to ace the clerkship: Section I: How to Succeed in the Psychiatry Clerkship Section II: High-Yield Facts; Examination and Diagnosis; Psychotic Disorders; Mood Disorders; Anxiety and Adjustment Disorders; Personality Disorders; Substance-Related Disorders; Cognitive Disorders; Geriatric Disorders; Psychiatric Disorders in Children; Dissociative Disorders; Somataform and Factitious Disorders; Impulse Control Disorders; Eating Disordes; Disorders; Sleep Disorders; Sexual Disorders; Psychtherapies; Psychopharmacology; Legal Issues; Section III: Awards and Opportunities.

    Each technique is introduced with a simple, jargon-free explanation, practical examples, and hands-on guidance for solving real problems with Excel or a TI-83/84 series calculator, including Plus models. Hate math? No sweat. You'll be amazed how little you need! For those who do have an interest in mathematics, optional "Equation Blackboard" sections review the equations that provide the foundations for important concepts. David M. Levine is a much-honored innovator in statistics education. He is Professor Emeritus of Statistics and Computer Information Systems at Bernard M. Baruch College (CUNY), and co-author of several best-selling books, including Statistics for Managers using Microsoft Excel, Basic Business Statistics, Quality Management, and Six Sigma for Green Belts and Champions. Instructional designer David F. Stephan pioneered the classroom use of personal computers, and is a leader in making Excel more accessible to statistics students. He has co-authored several textbooks with David M. Levine. Here's just some of what you'll learn how to do... Use statistics in your everyday work or study Perform common statistical tasks using a Texas Instruments statistical calculator or Microsoft Excel Build and interpret statistical charts and tables "Test Yourself" at the end of each chapter to review the concepts and methods that you learned in the chapter Work with mean, median, mode, standard deviation, Z scores, skewness, and other descriptive statistics Use probability and probability distributions Work with sampling distributions and confidence intervals Test hypotheses and decision-making risks with Z, t, Chi-Square, ANOVA, and other techniques Perform regression analysis and modeling The easy, practical introduction to statistics--for everyone! Thought you couldn't learn statistics? Think again. You can--and you will!

    And through CODE, we see how this ingenuity and our very human compulsion to communicate have driven the technological innovations of the past two centuries. Using everyday objects and familiar language systems such as Braille and Morse code, author Charles Petzold weaves an illuminating narrative for anyone who’s ever wondered about the secret inner life of computers and other smart machines. It’s a cleverly illustrated and eminently comprehensible story—and along the way, you’ll discover you’ve gained a real context for understanding today’s world of PCs, digital media, and the Internet. No matter what your level of technical savvy, CODE will charm you—and perhaps even awaken the technophile within.

    The most current information on the mechanisms, manifestations, and treatments of disease are clearly and concisely presented. Accessible writing, numerous illustrations in full-color, and complete and separate treatment of pediatric pathophysiology are the hallmarks of this popular and respected text. The new third edition features extensively revised and updated content and an enhanced art program.The book is divided into two parts. Part One presents the general principles of pathophysiology, including cell injury and repair; genetics; fluids and electrolytes, acids and bases; immunity, inflammation, and infection; stress; and cancer. Part Two is organized by body system, and for each system it covers normal anatomy and physiology, alterations of function in adults, and alterations of function in children.• Complete but concise coverage provides a thorough discussion of general pathophysiology and specific disease processes. • Outstanding full-color art program illustrates normal anatomy and physiology, disease processes, and clinical manifestations of disease. • Pediatric content is presented in 9 separate chapters to provide thorough coverage of how disease processes specifically affect children. • Health Alert boxes present brief discussions of new research, diagnostic studies, preventative care, treatments, or other developments related to health or specific diseases. • Quick Check questions appear at the end of major sections of text and are designed to promote critical thinking. Suggested answers to the questions are found on the CD companion included with the text. • Risk Factor boxes illustrate how certain risk factors are associated with specific diseases. • Did You Understand? chapter summaries provide students with a comprehensive review of the major concepts presented in each chapter. • Aging content is identified with a special icon within the adult chapters. • Algorithms are used throughout the text to illustrate normal and compensatory physiology and pathophysiology. • Key terms are boldface in text and listed with page numbers at the end of each chapter for easy reference and chapter review.• Approximately 250 new full-color drawings have been added. • An Introduction to Pathophysiology included in the front matter defines pathophysiology — and related terms such as etiology and epidemiology — and explains why it is important. • Extensive updates, based on the most current research, have been made throughout the book. • To reflect the latest developments, the Biology of Cancer chapter has been completely rewritten. • Several chapters, including Fluids and Electrolytes, Acids and Bases and Alterations of the Reproductive Systems have been extensively edited.

    It covers topics ranging from personal responsibility and career development to architectural techniques for keeping your code flexible and easy to adapt and reuse. Read this book, and you'll learn how toFight software rot; Avoid the trap of duplicating knowledge; Write flexible, dynamic, and adaptable code; Avoid programming by coincidence; Bullet-proof your code with contracts, assertions, and exceptions; Capture real requirements; Test ruthlessly and effectively; Delight your users; Build teams of pragmatic programmers; and Make your developments more precise with automation. Written as a series of self-contained sections and filled with entertaining anecdotes, thoughtful examples, and interesting analogies, The Pragmatic Programmer illustrates the best practices and major pitfalls of many different aspects of software development. Whether you're a new coder, an experienced programmer, or a manager responsible for software projects, use these lessons daily, and you'll quickly see improvements in personal productivity, accuracy, and job satisfaction. You'll learn skills and develop habits and attitudes that form the foundation for long-term success in your career. You'll become a Pragmatic Programmer.

    The books also provides a companion web site that provides the toold and materials necessary to build the hardware and software.