What is going on? Anatomy of an Epidemic challenges readers to think through that question themselves. First, Whitaker investigates what is known today about the biological causes of mental disorders. Do psychiatric medications fix “chemical imbalances” in the brain, or do they, in fact, create them? Researchers spent decades studying that question, and by the late 1980s, they had their answer. Readers will be startled—and dismayed—to discover what was reported in the scientific journals. Then comes the scientific query at the heart of this book: During the past fifty years, when investigators looked at how psychiatric drugs affected long-term outcomes, what did they find? Did they discover that the drugs help people stay well? Function better? Enjoy good physical health? Or did they find that these medications, for some paradoxical reason, increase the likelihood that people will become chronically ill, less able to function well, more prone to physical illness?  This is the first book to look at the merits of psychiatric medications through the prism of long-term results. Are long-term recovery rates higher for medicated or unmedicated schizophrenia patients? Does taking an antidepressant decrease or increase the risk that a depressed person will become disabled by the disorder? Do bipolar patients fare better today than they did forty years ago, or much worse? When the National Institute of Mental Health (NIMH) studied the long-term outcomes of children with ADHD, did they determine that stimulants provide any benefit?  By the end of this review of the outcomes literature, readers are certain to have a haunting question of their own: Why have the results from these long-term studies—all of which point to the same startling conclusion—been kept from the public?  In this compelling history, Whitaker also tells the personal stories of children and adults swept up in this epidemic. Finally, he reports on innovative programs of psychiatric care in Europe and the United States that are producing good long-term outcomes. Our nation has been hit by an epidemic of disabling mental illness, and yet, as Anatomy of an Epidemic reveals, the medical blueprints for curbing that epidemic have already been drawn up.

    The case would become one of the most famous in modern medicine—and a total failure. As Nature Made Him tells the extraordinary story of David Reimer, who, when finally informed of his medical history, made the decision to live as a male. A macabre tale of medical arrogance, it is first and foremost a human drama of one man's—and one family's—amazing survival in the face of terrible odds.

    Gang Leader for a Day is the fascinating full story of how Sudhir Venkatesh managed to gain entrée into the gang, what he learned, and how his method revolutionized the academic establishment. When Venkatesh walked into an abandoned building in one of Chicago's most notorious housing projects, he was looking for people to take a multiple-choice survey on urban poverty. A first-year grad student, he would befriend a gang leader named JT and spend the better part of the next decade inside the projects under JT's protection, documenting what he saw there. Over the next seven years, Venkatesh observed JT and the rest of the gang as they operated their crack selling business, conducted PR within their community, and rose up or fell within the ranks of the gang's complex organizational structure. Gang Leader for a Day is an inside view into the morally ambiguous, highly intricate, often corrupt struggle to survive in an urban war zone. It is also the story of a complicated friendship between two young and ambitious men, a universe apart.

    But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers--resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

    Alvord left a dusty reservation in New Mexico for Stanford University Medical School, becoming the first Navajo woman surgeon. Rising above the odds presented by her own culture and the male-dominated world of surgeons, she returned to the reservation to find a new challenge. In dramatic encounters, Dr. Alvord witnessed the power of belief to influence health, for good or for ill. She came to merge the latest breakthroughs of medical science with the ancient tribal paths to recovery and wellness, following the Navajo philosophy of a balanced and harmonious life, called Walking in Beauty. And now, in bringing these principles to the world of medicine, The Scalpel and the Silver Bear joins those few rare works, such as Healing and the Mind, whose ideas have changed medical practices-and our understanding of the world.

    His great-grandfather was beaten to death by the Klu Klux Klan for attempting to vote. His grandfather was prevented from voting by Klan intimidation; his father was barred by poll taxes and literacy tests. Today, Cotton cannot vote because he, like many black men in the United States, has been labeled a felon and is currently on parole."As the United States celebrates the nation's "triumph over race" with the election of Barack Obama, the majority of young black men in major American cities are locked behind bars or have been labeled felons for life. Although Jim Crow laws have been wiped off the books, an astounding percentage of the African American community remains trapped in a subordinate status--much like their grandparents before them.In this incisive critique, former litigator-turned-legal-scholar Michelle Alexander provocatively argues that we have not ended racial caste in America: we have simply redesigned it. Alexander shows that, by targeting black men and decimating communities of color, the U.S. criminal justice system functions as a contemporary system of racial control, even as it formally adheres to the principle of color blindness. The New Jim Crow challenges the civil rights community--and all of us--to place mass incarceration at the forefront of a new movement for racial justice in America.

    But Maurice Hilleman came close. Maurice Hilleman is the father of modern vaccines. Chief among his accomplishments are nine vaccines that practically every child gets, rendering formerly deadly diseases — including mumps, rubella, and measles — nearly forgotten. Author Paul A. Offit's rich and lively narrative details Hilleman's research and experiences as the basis for a larger exploration of the development of vaccines, covering two hundred years of medical history and traveling across the globe in the process. The history of vaccines necessarily brings with it a cautionary message, as they have come under assault from those insisting they do more harm than good. Paul Offit clearly and compellingly rebuts these arguments, and, by demonstrating how much the work of Hilleman and others has gained for humanity, shows us how much we have to lose.

    The government’s ferocious response, and the refusal of the demonstrators to back down, sparked a brutal civil war that over the past five years has escalated into the worst humanitarian catastrophe of our times.Yet despite all the reporting, the video, and the wrenching photography, the stories of ordinary Syrians remain unheard, while the stories told about them have been distorted by broad brush dread and political expediency. This fierce and poignant collection changes that. Based on interviews with hundreds of displaced Syrians conducted over four years across the Middle East and Europe, We Crossed a Bridge and It Trembled is a breathtaking mosaic of first-hand testimonials from the frontlines. Some of the testimonies are several pages long, eloquent narratives that could stand alone as short stories; others are only a few sentences, poetic and aphoristic. Together, they cohere into an unforgettable chronicle that is not only a testament to the power of storytelling but to the strength of those who face darkness with hope, courage, and moral conviction.

    Braided with that history is the moving story of Powers's beloved son Kevin--spirited, endearing, and gifted--who triumphed even while suffering from schizophrenia until finally he did not, and the story of his courageous surviving son Dean, who is also schizophrenic.A blend of history, biography, memoir, and current affairs ending with a consideration of where we might go from here, this is a thought-provoking look at a dreaded illness that has long been misunderstood.

    An award-winning investigative journalist, he used his real name; In American Prison, Bauer weaves a much deeper reckoning with his experiences together with a thoroughly researched history of for-profit prisons in America from their origins in the decades before the Civil War. For, as he soon realized, we can't understand the cruelty of our current system and its place in the larger story of mass incarceration without understanding where it came from. Private prisons became entrenched in the South as part of a systemic effort to keep the African-American labor force in place in the aftermath of slavery, and the echoes of these shameful origins are with us still.

    Most Americans could agree that no candidate like Donald Trump had ever been elected President before. But political journalist Ezra Klein makes the case that the 2016 election wasn't surprising at all. In fact, Trump's electoral victory followed the exact same template as previous elections, by capturing a nearly identical percentage of voter demographics as previous Republican candidates.Over the past 50 years in America, our partisan identities have merged with our racial, religious, geographic, ideological, and cultural identities. Those merged identities have attained a weight that is breaking much in our politics and tearing at the bonds that hold this country together.In this groundbreaking book, Klein shows how and why American politics polarized around identity in the 20th century, and what that polarization did to the way we see the world and each other. And he traces the feedback loops between our polarized political identities and our polarized political institutions that are driving our political system towards crisis.Neither a polemic nor a lament, Klein offers a clear framework for understanding everything from Trump's rise to the Democratic Party's leftward shift to the politicization of everyday culture. A revelatory book that will change how you look at politics, and perhaps at yourself.

    Focusing on two romances - Jessica's dizzying infatuation with a hugely successful young heroin dealer, Boy George, and Coco's first love with Jessica's little brother, Cesar - Random Family is the story of young people trying to outrun their destinies. Jessica and Boy George ride the wild adventure between riches and ruin, while Coco and Cesar stick closer to the street, all four caught in a precarious dance between survival and death. Friends get murdered; the DEA and FBI investigate Boy George; Cesar becomes a fugitive; Jessica and Coco endure homelessness, betrayal, the heartbreaking separation of prison, and, throughout it all, the insidious damage of poverty.Charting the tumultuous cycle of the generations - as girls become mothers, boys become criminals, and hope struggles against deprivation - LeBlanc slips behind the cold statistics and sensationalism and comes back with a riveting, haunting, and true story.

    Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    Methland tells the story of Oelwein, Iowa (pop. 6,159), which, like thousands of other small towns across the country, has been left in the dust by the consolidation of the agricultural industry, a depressed local economy, and an out-migration of people. As if this weren t enough to deal with, an incredibly cheap, longlasting, and highly addictive drug has rolled into town.Over a period of four years, journalist Nick Reding brings us into the heart of Oelwein through a cast of intimately drawn characters, including: Clay Hallburg, the town doctor, who fights meth even as he struggles with his own alcoholism; Nathan Lein, the town prosecutor, whose caseload is filled almost exclusively with meth-related crime; and Jeff Rohrick, a meth addict, still trying to kick the habit after twenty years. Tracing the connections between the lives touched by the drug and the global forces that set the stage for the epidemic, Methland offers a vital and unique perspective on a pressing contemporary tragedy.

    There is no cure. In a few days 90 percent of its victims are dead. A secret military SWAT team of soldiers and scientists is mobilized to stop the outbreak of this exotic "hot" virus. The Hot Zone tells this dramatic story, giving a hair-raising account of the appearance of rare and lethal viruses and their "crashes" into the human race. Shocking, frightening, and impossible to ignore, The Hot Zone proves that truth really is scarier than fiction.