Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    When Dr. Judy Mikovits finished her presentation the room was silent for a moment, then one of the scientists said, �Oh my God!” The resulting investigation would be like no other in science.For Dr. Mikovits, a twenty-year veteran of the National Cancer Institute, this was the midpoint of a five-year journey that would start with the founding of the Whittemore-Peterson Institute for Neuro-Immune Disease at the University of Nevada, Reno, and end with her as a witness for the federal government against her former employer, Harvey Whittemore, for illegal campaign contributions to Senate Majority Leader Harry Reid.On this journey Dr. Mikovits would face the scientific prejudices against CFS, wander into the minefield that is autism, and through it all struggle to maintain her faith in God and the profession to which she had dedicated her life. This is a story for anybody interested in the peril and promise of science at the very highest levels in our country.

    Are you the type of person who tilts at windmills, or the one who prefers to view them from the comfort of an air-conditioned motorcoach? Our personalities are endlessly fascinating—not just to ourselves but also to our spouses, our parents, our children, our co-workers, our neighbors. As a highly social species, humans have to navigate among an astonishing variety of personalities. But how did all these different permutations come about? And what purpose do they serve? With her trademark wit and sly humor, Hannah Holmes takes readers into the amazing world of personality and modern brain science. Using the Five Factor Model, which slices temperaments into the major factors (Extraversion, Neuroticism, Agreeableness, Conscientiousness, and Openness) and minor facets (such as impulsive, artistic, or cautious), Holmes demonstrates how our genes and brains dictate which factors and facets each of us displays. Are you a Nervous Nelly? Your amygdala is probably calling the shots. Hyperactive Hal? It’s all about the dopamine. Each facet took root deep in the evolution of life on Earth, with Nature allowing enough personal variation to see a species through good times and bad. Just as there are introverted and extroverted people, there are introverted and extroverted mice, and even starfish. In fact, the personality genes we share with mice make them invaluable models for the study of disorders like depression, schizophrenia, and anxiety. Thus it is deep and ancient biases that guide your dealings with a very modern world. Your personality helps to determine the political party you support, the car you drive, the way you eat M&Ms, and the likelihood that you’ll cheat on your spouse. Drawing on data from top research laboratories, the lives of her eccentric friends, the conflicts that plague her own household, and even the habits of her two pet mice, Hannah Holmes summarizes the factors that shape you. And what she proves is that it does take all kinds. Even the most irksome and trying personality you’ve ever encountered contributes to the diversity of our species. And diversity is the key to our survival.

    In Written in Bones, significant discoveries are carefully brought together and analyzed. Readers learn how experts use modern scientific techniques to piece together the stories behind the bones. The data is used to create a picture of cultures and ritual beliefs. There are such astonishing discoveries as:Han Dynasty aristocrat preserved in an unknown red liquid Bog bodies in Europe The riddle of Tomb KV55 - where a male body was found inside a female coffin World's oldest dwarf The headless men and giant wolves of the Mesolithic cemetery in Siberia

    Immerse yourself in the history of medicine - a colourful story of skill, serendipity, trial and error, moments of genius, and dogged determination.From traditional chinese medicine to today's sophisticated gene therapies and robotic surgery, A Short History of Medicine combines riveting storytelling and beautiful images, historical accounts and lucid explanations, to illuminate the story of medicine through time.Witness early, bloody, anaesthetic-free operations; see the first crude surgical instruments; trace the mapping of the circulatory system; follow the painstaking detective work that led to the decoding of the human genome; and understand the role that potions, cures, therapies, herbal medicines, and drugs have played in the human quest to tame and conquer disease, injury, and death.A Short History of Medicine is an engrossing illustrated history and tale of drama and discovery that celebrates the milestones of medical history across generations and cultures.

    This clear, concise look at the basic principles and concepts of genetics uses a human genetics perspective to discuss the methods and experiments upon which genetic principles are based, such as DNA replication.

    It has become known for its engaging writing style, instructional art program and focus on active learning. We are so excited to offer a robust learning program with student-focused learning activities, allowing the student to manage their learning while you easily manage their assessment. Detailed reports show how your assignments measure various learning objectives from the book (or input your own!), levels of Bloom's Taxonomy or other categories, and how your students are doing. The Cowan Learning program will save you time and improve your student's success in this course.

    You discover how fundamental principles and concepts relate to everyday life. Plus, you get plenty of study tips to improve your grades and score higher on exams! Explore the world of the cell — take a tour inside the structure and function of cells and see how viruses attack and destroy them Understand the stuff of life (molecules) — get up to speed on the structure of atoms, types of bonds, carbohydrates, proteins, DNA, RNA, and lipids Watch as cells function and reproduce — see how cells communicate, obtain matter and energy, and copy themselves for growth, repair, and reproduction Make sense of genetics — learn how parental cells organize their DNA during sexual reproduction and how scientists can predict inheritance patterns Decode a cell's underlying programming — examine how DNA is read by cells, how it determines the traits of organisms, and how it's regulated by the cell Harness the power of DNA — discover how scientists use molecular biology to explore genomes and solve current world problems Open the book and find: Easy-to-follow explanations of key topics The life of a cell — what it needs to survive and reproduce Why molecules are so vital to cells Rules that govern cell behavior Laws of thermodynamics and cellular work The principles of Mendelian genetics Useful Web sites Important events in the development of DNA technology Ten great ways to improve your biology grade

    This new edition, written with five new authors, has been brought fully up to date, and incorporates insights very recently derived from genome sequencing in a variety of organisms. The book is an authoritative and comprehensive survey of the fundamentals of molecular biology, from basic mechanisms to the elaborate role of gene regulation in embryonic development and evolution. Although updated, the twentyone chapters of the new edition retain the distinctive and celebrated features of the original work, including introductory chapters on the history of genetics and molecular biology and an emphasis throughout on the chemical underpinnings of molecular biology. The new team of authors brings to this edition awardwinning teaching experience and outstanding research achievements. By revealing the intellectual framework and experimental approaches that made new discoveries in the field possible, the new edition highlights the significance of the molecular approach for all of biology.

    If you suffer from ailments your doctors can’t seem to diagnose or help—mysterious rashes, unpredictable digestive problems, debilitating headaches, mood and energy swings, constant tiredness—nerve compression is the likely cause. Over the years, Dr. Richard Jacoby has treated thousands of patients with peripheral neuropathy. Now, he shares his insights as well as the story of how he connected the dots to determine how sugar is the common denominator of many chronic diseases. In Sugar Crush, he offers a unique holistic approach to understanding the exacting toll sugar and carbs take on the body. Based on his clinical work, he breaks down his highly effective methods, showing how dietary changes reducing sugar and wheat, coinciding with an increase of good fats, can dramatically help regenerate nerves and rehabilitate their normal function.Sugar Crush includes a quiz to assess your nerve damage, practical dietary advice, and the latest thinking on ways to prevent and reverse neuropathy. If you have diabetes, this essential guide will help you understand the dangers and give you the tools you need to make a difference beyond your doctor’s prescriptions. If you have the metabolic syndrome or prediabetes, or are just concerned about your health, it will help you reverse and prevent nerve damage.

    

    In The Compatibility Gene, one of our foremost immunologists tells the remarkable history of these genes' discovery and the unlocking of their secrets. Davis shows how the compatibility gene is radically transforming our knowledge of the way our bodies work - and is having profound consequences for medical research and ethics. Looking to the future, he considers the startling possibilities of what these wondrous discoveries might mean for you and me.

    This popular Blueprints book has been refined and updated while keeping the concise, organized style and clinical high-yield content of previous editions. Features include USMLE-style questions and answers with full explanations; Key Points in every section; and a color-enhanced design that increases the usefulness of figures and tables.This edition's completely revised art program includes many additional illustrations. Each chapter in this edition ends with evidence-based references (journals) for students to do additional reading/research.

    Written By Two Of Today'S Most Respected Computer Science Educators, Nell Dale And John Lewis, The Text Provides A Broad Overview Of The Many Aspects Of The Discipline From A Generic View Point. Separate Program Language Chapters Are Available As Bundle Items For Those Instructors Who Would Like To Explore A Particular Programming Language With Their Students. The Many Layers Of Computing Are Thoroughly Explained Beginning With The Information Layer, Working Through The Hardware, Programming, Operating Systems, Application, And Communication Layers, And Ending With A Discussion On The Limitations Of Computing. Perfect For Introductory Computing And Computer Science Courses, Computer Science Illuminated, Third Edition's Thorough Presentation Of Computing Systems Provides Computer Science Majors With A Solid Foundation For Further Study, And Offers Non-Majors A Comprehensive And Complete Introduction To Computing.

    A school cafeteria lunch is infected with a drug-resistant strain of E. coli.... Thousands in a bustling shopping mall inhale a lethal mist of smallpox, turning each individual into a highly infectious agent of suffering and death....Dr. Michael Osterholm knows all too well the horrifying scenarios he describes. In this eye-opening account, the nation’s leading expert on bioterrorism sounds a wake-up call to the terrifying threat of biological attack — and America’s startling lack of preparedness. He demonstrates the havoc these silent killers can wreak, exposes the startling ease with which they can be deployed, and asks probing questions about America’s ability to respond to such attacks. Are most doctors and emergency rooms able to diagnose correctly and treat anthrax, smallpox, and other potential tools in the bioterrorist’s arsenal? Is the government developing the appropriate vaccines and treatments? The answers are here in riveting detail — what America has and hasn’t done to prevent the coming bioterrorist catastrophe. Impeccably researched, grippingly told, Living Terrors presents the unsettling truth about the magnitude of the threat. And more important, it presents the ultimate insider’s prescription for change: what we must do as a nation to secure our freedom, our future, our lives.