The books explores medical and scientific themes in a fictional way and it is difficult to think of an earlier book that does this. Although he was not a doctor, Sinclair Lewis's father was and he was greatly helped in the preparation of the manuscript by the science writer Paul de Kruif. It was de Kruif who brings a reality to the book that is almost biographical.This reality means that the books heralds the real impact of advances in drugs, public health, and immunology that were about to change the world. It also satirises those medical and scientific practitioners whose pursuit of fame and fortune, at the expense of truth, remains just as pertinent today.The book was first published in 1925 and was a popular and commercial success. It was awarded a Pulitzer Prize in 1926 which was refused by Sinclair Lewis. He was later to win the Nobel Prize for Literature—which he accepted.

    Even before the Great Depression struck, Jeeter Lester and his family were desperately poor sharecroppers. But when hard times begin to affect the families that once helped support them, the Lesters slip completely into the abyss. Rather than hold on to each other for support, Jeeter, his wife Ada, and their twelve children are overcome by the fractured and violent society around them. Banned and burned when first released in 1932, Tobacco Road is a brutal examination of poverty’s dehumanizing influence by one of America’s great masters of political fiction.

    Grace Strasser-Mendana controls much of the country's wealth and knows virtually all of its secrets; Charlotte Douglas knows far too little. "Immaculate of history, innocent of politics," she has come to Boca Grande vaguely and vainly hoping to be reunited with her fugitive daughter. As imagined by Didion, her fate is at once utterly particular and fearfully emblematic of an age of conscienceless authority and unfathomable violence.

    In the retelling, Olympus becomes small-town Olinger High School; Chiron is George Caldwell, a science teacher there; and Prometheus is Caldwell’s fifteen-year-old son, Peter. Brilliantly conflating the author’s remembered past with tales from Greek mythology, John Updike translates Chiron’s agonized search for relief into the incidents and accidents of three winter days spent in rural Pennsylvania in 1947. The result, said the judges of the National Book Award, is “a courageous and brilliant account of a conflict in gifts between an inarticulate American father and his highly articulate son.”

    His brother, a slumlord, hires him to collect rent in the buildings he owns in Manhattan. Making his rounds from apartment to apartment, Moonbloom confronts a wildly varied assortment of brilliantly described urban characters, among them a gay jazz musician with a sideline as a gigolo, a Holocaust survivor, and a brilliant young black writer modeled on James Baldwin. Moonbloom hears their cries of outrage and abuse; he learns about their secret sorrows and desires. And as he grows familiar with their stories, he finds that he is drawn, in spite of his best judgment, into a desperate attempt to improve their lives.Edward Lewis Wallant's astonishing comic tour de force is a neglected masterpiece of 1960s America.

    From his base in Tangier he produced globally ranging novels, stories, and travel writings that set exquisite surfaces over violent undercurrents. His elegantly spare novels chart the unpredictable collisions between "civilized" exiles and a Morocco they never grasp, achieving effects of extreme horror and dislocation.This Library of America Bowles set, the first annotated edition, offers the full range of his achievement: the portrait of an outsider who was one of the essential American writers of the last century. In addition to his novels -- The Sheltering Sky (1949), Let It Come Down (1952), The Spider's House (1955), Up Above the World (1966) -- and his collected stories -- including such classics as "A Distant Episode" and "Pages from Cold Point" -- they contain his masterpiece of travel writing, Their Heads Are Green and Their Hands Are Blue (1963). Throughout, Bowles shows himself a master of gothic terror and a diabolically funny observer of manners as well as a prescient guide to everything from the roots of Islamist politics to the world of Moghrebi music. With a hallucinatory clarity as dry and unforgiving as the desert air, Bowles sends his characters toward encounters with unknown and terrifying forces both outside them and within them.

    But as night falls and the season begins to change, Neddy sinks from optimistic bliss to utter despair.

    First published in Norway as two books in 1924 and 1925, the author collaborated with Minnesotan Lincoln Colcord on the English translation.The novel follows a Norwegian family's struggles as they try to make a new life as pioneers in the Dakota territory. Rølvaag is interested in psychology and the human cost of empire building, at a time when other writers focused on the glamor and romance of the West. The book reflects his personal experiences as a settler as well as the immigrant homesteader experience of his wife’s family. Both the grim realities of pioneering and the gloomy fatalism of the Norse mind are captured in depictions of snow storms, locusts, poverty, hunger, loneliness, homesickness, the difficulty of fitting into a new culture, and the estrangement of immigrant children who grow up in a new land. It is a novel at once palpably European and distinctly American.Giants in the Earth was turned into an opera by Douglas Moore and Arnold Sundgaard; it won the Pulitzer Prize for Music in 1951.

    From local bars to train yards to prison, it's the story of two young men, bound to the town by family, responsibility, inertia, and the beauty around them, who dream of a future beyond the factories and abandoned homes.Left alone to care for his aging father after his mother commits suicide and his sister escapes to Yale, Isaac English longs for a life beyond his hometown. When he finally sets out to leave for good, accompanied by his temperamental best friend, they are caught up in a terrible act of violence that changes their lives forever.Evoking John Steinbeck’s novels of restless lives during the Great Depression, American Rust delves into the contemporary American heartland at a moment of profound unrest and uncertainty about the future. It's a dark but lucid vision, a moving novel about the bleak realities that battle our desire for transcendence and the power of love and friendship to redeem us.

    For his centennial, The Library of America inaugurates its Macdonald edition with four classic novels from the 1950s, all featuring his incomparable protagonist, private investigator Lew Archer.Set against the background of a glittering yet darkly enigmatic Southern California, Macdonald’s books are both unsurpassed entertainments and emotionally powerful evocations of an outwardly prosperous, inwardly turbulent America. Macdonald mastered the hard-boiled detective form early on and brought to it a prose style of extraordinary beauty. The four novels collected in this volume reveal him broadening the genre into an intensely personal means of expression, transforming the tragedies and dislocations of his own life into haunting fiction. “My interest,” he wrote to his publisher, “is the exploration of lives.”In The Way Some People Die, Lew Archer embarks on a missing persons case that starts at a house in Santa Monica “within earshot of the coast highway and rifleshot of the sea,” and takes him on a violent and twisted journey through Los Angeles high and low. The Barbarous Coast exposes a world of hidden crime and corruption in the movie business, as Archer intrudes on the well-protected secrets of a studio head. A gripping and tightly knit drama of madness and self-destruction, The Doomsters signaled a breakthrough in the Archer novels with its exploration of “an alternating current of guilt” within a family, a theme to which Macdonald would often return. The Galton Case, one of the standout masterpieces of the detective form, is a mythically charged and deeply personal book that traces the calamitous consequences of a young man’s claim to be the lost heir to a fortune. For Macdonald The Galton Case marked a turning point in his career, the realization of his quest to create fiction from “some of the more complicated facts of my experience.”As a special feature, this volume includes five important statements—among them the famous essay “Writing The Galton Case”—in which Macdonald reveals the autobiographical background of his books and his understanding of his own contribution to the evolving genre of detective fiction.

    This comprehensive collection includes all his most accomplished and best-known works: five novels, short stories, journalism, war correspondence, and his two completed books of poetry.Here are the classic novels he published in a span of five years: The Red Badge of Courage (1895), about a young and confused Union soldier under fire for the first time; Maggie: A Girl of the Streets (1893), a vivid portrait of slum life and a young girl’s fall; George’s Mother (1896), about New York’s Bowery and its effect on a young workingman fresh from the country; The Third Violet (1897), the story of a bohemian artist’s country romance; and The Monster (1899), a novella about sacrifice and rescue, guilt and isolation.Among his short stories are such masterpieces as “The Open Boat,” “The Blue Hotel,” and “The Bride Comes to Yellow Sky.” His prose is at the same time dense and lean, suited to his description of the elusive forces that impinge upon his characters, and suited also to his desire not to circumscribe them with traditional moral and interpretive definition. Included here as well are the Whilomville stories of children and childhood in small-town America and the Sullivan County sketches of turn-of-the-twentieth-century rural life.As a journalist, Crane covered the Spanish-American War and the Greco-Turkish War, traveled through Mexico and the West, and reported on the seamier sides of New York City life; the best of his dispatches are gathered here. Also featured are both of Crane’s collections of epigrammatic free verse—The Black Riders (1895) and War is Kind (1899)—and selections from his uncollected poems. His poetry shows strong affinities to Emily Dickinson, while also anticipating the Imagist movement later in the twentieth century.This is the most substantial gathering of Crane’s work ever made available in one volume; it is an enduring testimony to his heroic achievement.

    The family house is in the small Far West town of Fingerbone set on a glacial lake, the same lake where their grandfather died in a spectacular train wreck, and their mother drove off a cliff to her death. It is a town "chastened by an outsized landscape and extravagant weather, and chastened again by an awareness that the whole of human history had occurred elsewhere." Ruth and Lucille's struggle toward adulthood beautifully illuminates the price of loss and survival, and the dangerous and deep undertow of transience.

    But even though this gutsy 14-year-old is seeking vengeance, she is smart enough to figure out she can't go alone after a desperado who's holed up in Indian territory. With some fast-talking, she convinces mean, one-eyed US Marshal "Rooster" Cogburn into going after the despicable outlaw with her.

    But he has yet to meet the test of human conflict. In a tale of violent action and superbly sustained suspense, the harsh realities of tribal warfare force him to kill his first foe, then face torture at the stake. Still yet another kind of initiation awaits him when he discovers not only the ruthlessness of "civilized" men, but also the special danger of a woman's will. His reckless spirit transformed into mature courage and moral certainty, the Deerslayer emerges to face life with nobility as pure and proud as the wilderness whose fierce beauty and freedom have claimed his heart.

    Living on the fringe of society, these two outcasts develop an unlikely bond. This is the book on which the Academy Award-winning film was based.