She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.

    But in her mother, a would-be artist burdened by the endless arrival of new babies, young Kate saw the consequences of a dream deferred. Determined to pursue her own no matter the cost, at 18 she left her small Midwestern town for New York, where, studying with the legendary Stella Adler, she learned the lesson that would define her as an actress: "Use it," Adler told her. Whatever disappointment, pain, or anger life throws in your path, channel it into the work.It was a lesson she would need. At twenty-two, just as her career was taking off, she became pregnant and gave birth to a daughter. Having already signed the adoption papers, she was allowed only a fleeting glimpse of her child. As her star continued to rise, her life became increasingly demanding and fulfilling, a whirlwind of passionate love affairs, life-saving friendships, and bone-crunching work. Through it all, Mulgrew remained haunted by the loss of her daughter, until, two decades later, she found the courage to face the past and step into the most challenging role of her life, both on and off screen.We know Kate Mulgrew for the strong women she's played--Captain Janeway on Star Trek; the tough-as-nails "Red" on Orange is the New Black. Now, we meet the most inspiring and memorable character of all: herself. By turns irreverent and soulful, laugh-out-loud funny and heart-piercingly sad, BORN WITH TEETH is the breathtaking memoir of a woman who dares to live life to the fullest, on her own terms.

    His contribution to our understanding not only of mental illness but also of the human condition is truly stunning.The Noonday Demon examines depression in personal, cultural, and scientific terms. Drawing on his own struggles with the illness and interviews with fellow sufferers, doctors and scientists, policymakers and politicians, drug designers and philosophers, Solomon reveals the subtle complexities and sheer agony of the disease. He confronts the challenge of defining the illness and describes the vast range of available medications, the efficacy of alternative treatments, and the impact the malady has had on various demographic populations around the world and throughout history. He also explores the thorny patch of moral and ethical questions posed by emerging biological explanations for mental illness.The depth of human experience Solomon chronicles, the range of his intelligence, and his boundless curiosity and compassion will change the reader's view of the world.

    Not ready to settle down and in need of an escape from her fast-paced job as a sitcom writer, Kristin instead traveled the world, often alone, for several weeks each year. In addition to falling madly in love with the planet, Kristin fell for many attractive locals, men who could provide the emotional connection she wanted without costing her the freedom she desperately needed. Kristin introduces readers to the Israeli bartenders, Finnish poker players, sexy Bedouins, and Argentinean priests who helped her transform into "Kristin-Adjacent" on the road–a slower, softer, and, yes, sluttier version of herself at home.

    Detroit, once the richest city in the nation, is now its poorest. Once the vanguard of America’s machine age—mass production, automobiles, and blue-collar jobs—Detroit is now America’s capital for unemployment, illiteracy, foreclosure, and dropouts. A city the size of San Francisco and Manhattan could neatly fit into Detroit’s vacant lots. In another life, Charlie LeDuff won the Pulitzer Prize reporting for The New York Times. But all that is behind him now, after returning to find his hometown in total freefall. Detroit is where his mother’s flower shop was firebombed; where his sister lost herself to drugs; where his brother works in a factory cleaning Chinese-manufactured screws so they can be repackaged as “Made in America.” With the steel-eyed reportage that has become his trademark—and the righteous indignation only a native son possesses—LeDuff sets out to uncover what destroyed his city. He embeds with a local fire brigade struggling to defend its neighborhood against systemic arson and bureaucratic corruption. He investigates state senators and career police officials, following the money to discover who benefits from Detroit’s decline. He befriends union organizers, homeless do-gooders, embattled businessmen, and struggling homeowners, all ordinary people holding the city together by sheer determination. Americans have hoped for decades that Detroit was an exception, an outlier. What LeDuff reveals is that Detroit is, once and for all, America’s city: It led us on the way up, and now it is leading us on the way down. Detroit can no longer be ignored because what happened there is happening out here. Redemption is thin on the ground in this ghost of a city, but Detroit: An American Autopsy is no hopeless parable. Instead, LeDuff shares a deeply human drama of colossal greed, ignorance, endurance, and courage. Detroit is an unbelievable story of a hard town in a rough time filled with some of the strangest and strongest people our country has to offer—and a black comic tale of the absurdity of American life in the twenty-first century.

    That simple act became a national news story because Abby was the director of a Planned Parenthood clinic in Texas who, after participating in her first actual abortion procedure, walked across the road to join the Coalition for Life. "Unplanned" is a heartstopping personal drama of life-and-death encounters, a courtroom battle, and spiritual transformation that speaks hope and compassion into the political controversy that surrounds this issue. Telling Abby’s story from both sides of the abortion clinic property line, this book is a must-read for anyone who cares about the life versus rights debate and helping women who face crisis pregnancies.

    They ate braised leeks. They played by themselves while their parents sipped coffee. And yet French kids were still boisterous, curious, and creative. Why? How?            With a notebook stashed in her diaper bag, Druckerman set out to investigate—and wound up sparking a national debate on parenting. Researched over three years and written in her warm, funny voice, Bringing Up Bébé is deeply wise, charmingly told, and destined to become a classic resource for American parents.

    Kathryn Mannix has studied and practiced palliative care for thirty years. In With the End in Mind , she shares beautifully crafted stories from a lifetime of caring for the dying, and makes a case for the therapeutic power of approaching death not with trepidation, but with openness, clarity, and understanding. Weaving the details of her own experiences as a caregiver through stories of her patients, their families, and their distinctive lives, Dr. Mannix discusses the universal, but deeply personal, process of dying. With meditations on life, death, and the space between them, With the End in Mind describes the possibility of meeting death gently, with forethought and preparation, and shows the unexpected beauty, dignity, and profound humanity of life coming to an end.

    Mary Anne Schwalbe is waiting for her chemotherapy treatments when Will casually asks her what she's reading. The conversation they have grows into tradition: soon they are reading the same books so they can have something to talk about in the hospital waiting room. The ones they choose range from classic to popular, from fantastic to spiritual, and we hear their passion for reading and their love for each other in their intimate and searching discussions. A profoundly moving testament to the power of love between a child and parent, and the power of reading in our lives.

    America faced a troubling question: What happened? How was this epidemic allowed to spread so far before it was taken seriously? In answering these questions, Shilts weaves the disparate threads into a coherent story, pinning down every evasion and contradiction at the highest levels of the medical, political, and media establishments. Shilts shows that the epidemic spread wildly because the federal government put budget ahead of the nation's welfare; health authorities placed political expediency before the public health; and scientists were often more concerned with international prestige than saving lives. Against this backdrop, Shilts tells the heroic stories of individuals in science and politics, public health and the gay community, who struggled to alert the nation to the enormity of the danger it faced. And the Band Played On is both a tribute to these heroic people and a stinging indictment of the institutions that failed the nation so badly.

    Here, nurses remember their first “sticks,” first births, and first deaths, and reflect on what gets them though long, demanding shifts, and keeps them in the profession. The stories reveal many voices from nurses at different stages of their careers: One nurse-in-training longs to be trusted with more “important” procedures, while another questions her ability to care for nursing home residents. An efficient young emergency room nurse finds his life and career irrevocably changed by a car accident. A nurse practitioner wonders whether she has violated professional boundaries in her care for a homeless man with AIDS, and a home care case manager is the sole attendee at a funeral for one of her patients. What connects these stories is the passion and strength of the writers, who struggle against burnout and bureaucracy to serve their patients with skill, empathy, and strength.

    But work takes a strange turn when she is promoted onto the Pfizer account and suddenly finds herself on the other side of the curtain, developing ads for an anti-depressant drug. Overwhelmed by her professional life and the self-scrutiny it inspires, her mania takes hold. She quits her job to become an artist, only to be hospitalized by her parents against her will. Over the course of her two weeks in the ward, she tries to find a path out of the hospital and this cycle of treatment. One where she can live the life she wants, finding freedom and autonomy, without sacrificing her dreams in order to stay well.

    She moved from New York to San Francisco, where she landed at a big-data startup in the heart of the Silicon Valley bubble: a world of surreal extravagance, dubious success, and fresh-faced entrepreneurs hell-bent on domination, glory, and, of course, progress.Anna arrived amidst a massive cultural shift, as the tech industry rapidly transformed into a locus of wealth and power rivaling Wall Street. But amid the company ski vacations and in-office speakeasies, boyish camaraderie and ride-or-die corporate fealty, a new Silicon Valley began to emerge: one in far over its head, one that enriched itself at the expense of the idyllic future it claimed to be building.Part coming-age-story, part portrait of an already-bygone era, Anna Wiener’s memoir is a rare first-person glimpse into high-flying, reckless startup culture at a time of unchecked ambition, unregulated surveillance, wild fortune, and accelerating political power. With wit, candor, and heart, Anna deftly charts the tech industry’s shift from self-appointed world savior to democracy-endangering liability, alongside a personal narrative of aspiration, ambivalence, and disillusionment.Unsparing and incisive, Uncanny Valley is a cautionary tale, and a revelatory interrogation of a world reckoning with consequences its unwitting designers are only beginning to understand.

    She was also generous. When Anna proposed an all-expenses-paid trip to Marrakech, Rachel jumped at the chance. But when Anna’s credit cards mysteriously stopped working, the dream vacation quickly took a dark turn. Anna asked Rachel to begin fronting costs—first for flights, then meals and shopping, and, finally, for their $7,500-per-night private villa. Before Rachel knew it, more than $62,000 had been charged to her credit cards. Anna swore she would reimburse Rachel the moment they returned to New York. Back in Manhattan, the repayment never materialized, and a shocking pattern of deception emerged. Rachel learned that Anna had left a trail of deceit—and unpaid bills—wherever she’d been. Mortified, Rachel contacted the district attorney, and in a stunning turn of events, found herself helping to bring down one of the city’s most notorious con artists.

    He’s an established legend, having starred in Mary Poppins, Chitty Chitty Bang Bang, and The Dick Van Dyke Show. And yet he’s still keeping himself busy, entertaining America on television, movies, the stage, and social media. Everyone wonders, “How does he do it?” For the first time, Van Dyke shares his secrets and tips on old age: Just keep moving. In a fun and folksy way of addressing readers, Keep Moving serves as an instruction book on how to embrace old age with a positive attitude. The chapters are filled with exclusive personal anecdotes that explore various themes on aging: how to adapt to the physical and social changes, deal with loss of friends and loved ones, stay current, fall in love again, and “keep moving” every day like there’s no tomorrow.