Book picks similar to
Darwin: The Five Essential Works by Charles Darwin
old-classiques
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genetics
Tears of the Cheetah: The Genetic Secrets of Our Animal Ancestors
Stephen J. O'Brien - 2003
If animals could talk, we would ask them to recall their own ancestries, in particular the secrets as to how they avoided almost inevitable annihilation in the face of daily assaults by predators, climactic cataclysms, deadly infections and innate diseases.In Tears of the Cheetah, medical geneticist and conservationist Stephen J. O'Brien narrates fast-moving science adventure stories that explore the mysteries of survival among the earth's most endangered and beloved wildlife. Here we uncover the secret histories of exotic species such as Indonesian orangutans, humpback whales, and the imperiled cheetah-the world's fastest animal which nonetheless cannot escape its own genetic weaknesses.Among these genetic detective stories we also discover how the Serengeti lions have lived with FIV (the feline version of HIV), where giant pandas really come from, how bold genetic action pulled the Florida panther from the edge of extinction, how the survivors of the medieval Black Death passed on a genetic gift to their descendents, and how mapping the genome of the domestic cat solved a murder case in Canada.With each riveting account of animal resilience and adaptation, a remarkable parallel in human medicine is drawn, adding yet another rationale for species conservation-mining their genomes for cures to our own fatal diseases. Tears of the Cheetah offers a fascinating glimpse of the insight gained when geneticists venutre into the wild.
Little Boy Blue: A Puppy's Rescue from Death Row and His Owner's Journey for Truth
Kim Kavin - 2012
She had no idea that the adorable brindle puppy—advertised as healthy and near her home in New Jersey—was actually a last-minute rescue from a gas-chamber shelter in North Carolina. Blue had arrived in the Northeast with at least a dozen other dogs in an RV that is just one among countless transports whose sponsors are dedicating their efforts to saving dogs by any means possible. Blue was happy and friendly, but he seemed to have endured some unusual albeit unknown ordeal. The dog’s manner prompted Kavin to trace his history all the way back to a long row of cages where Blue had been tagged to be put down in just three more days. Little Boy Blue is the true story of one sweet puppy’s journey of survival. It’s also a shocking exposé that describes a brutal ongoing reality inside some of this country’s taxpayer-funded shelters. But Little Boy Blue also tells an inspiring story of the grass-roots rescue network that has exploded across the nation in recent years. Readers will come to know and love a very special dog who now brings smiles to the faces of everyone he meets. From a single click of Kim Kavin’s computer mouse, Blue’s journey of a lifetime began. This is the story of Little Boy Blue, told with candor and a great deal of love. Readers will see Blue and other foster dogs that have been rescued by Kim Kavin in this book’s color photo insert.A portion of the proceeds from the sale of this book will donated to the Petfinder.com Foundation.From the Reviews:"A moving call to action."—Kirkus Reviews
Rosalind Franklin: The Dark Lady of DNA
Brenda Maddox - 2002
Brenda Maddox tells a powerful story of a remarkably single-minded, forthright, and tempestuous young woman who, at the age of fifteen, decided she was going to be a scientist, but who was airbrushed out of the greatest scientific discovery of the twentieth century.
The Monk in the Garden: The Lost and Found Genius of Gregor Mendel, the Father of Genetics
Robin Marantz Henig - 2000
Shrouded in mystery, Gregor Mendel's quiet life and discoveries make for fascinating reading. Among his pea plants Henig finds a tale filled with intrigue, jealousy, and a healthy dose of bad timing. She "has done a remarkable job of fleshing out the myth with what few facts there are" (Washington Post Book World) and has delivered Mendel's story with grace and glittering prose. THE MONK IN THE GARDEN is both a "classic tale of redemption" (New York Times Book Review) and a science book of the highest literary order.
Lone Survivors: How We Came to Be the Only Humans on Earth
Chris Stringer - 2011
Stringer's new theory, based on archeological and genetic evidence, holds that distinct humans coexisted and competed across the African continent—exchanging genes, tools, and behavioral strategies.Stringer draws on analyses of old and new fossils from around the world, DNA studies of Neanderthals (using the full genome map) and other species, and recent archeological digs to unveil his new theory. He shows how the most sensational recent fossil findings fit with his model, and he questions previous concepts (including his own) of modernity and how it evolved.Lone Survivors will be the definitive account of who and what we were, and will change perceptions about our origins and about what it means to be human.
Gene Machine: The Race to Decipher the Secrets of the Ribosome
Venki Ramakrishnan - 2018
But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.
Origins: How the Nine Months Before Birth Shape the Rest of Our Lives
Annie Murphy Paul - 2010
Others are sure it's the environment we experience in childhood. But could it be that many of our individual characteristics—our health, our intelligence, our temperaments—are influenced by the conditions we encountered before birth? That's the claim of an exciting and provocative field known as fetal origins. Over the past twenty years, scientists have been developing a radically new understanding of our very earliest experiences and how they exert lasting effects on us from infancy well into adulthood. Their research offers a bold new view of pregnancy as a crucial staging ground for our health, ability, and well-being throughout life.Author and journalist Annie Murphy Paul ventures into the laboratories of fetal researchers, interviews experts from around the world, and delves into the rich history of ideas about how we're shaped before birth. She discovers dramatic stories: how individuals gestated during the Nazi siege of Holland in World War II are still feeling its consequences decades later; how pregnant women who experienced the 9/11 attacks passed their trauma on to their offspring in the womb; how a lab accident led to the discovery of a common household chemical that can harm the developing fetus; how the study of a century-old flu pandemic reveals the high personal and societal costs of poor prenatal experience. Origins also brings to light astonishing scientific findings: how a single exposure to an environmental toxin may produce damage that is passed on to multiple generations; how conditions as varied as diabetes, heart disease, and mental illness may get their start in utero; why the womb is medicine's latest target for the promotion of lifelong health, from preventing cancer to reducing obesity. The fetus is not an inert being, but an active and dynamic creature, responding and adapting as it readies itself for life in the particular world it will enter. The pregnant woman is not merely a source of potential harm to her fetus, as she is so often reminded, but a source of influence on her future child that is far more powerful and positive than we ever knew. And pregnancy is not a nine-month wait for the big event of birth, but a momentous period unto itself, a cradle of individual strength and wellness and a crucible of public health and social equality.With the intimacy of a personal memoir and the sweep of a scientific revolution, Origins presents a stunning new vision of our beginnings that will change the way you think about yourself, your children, and human nature itself.
Introduction to Genetic Analysis
Anthony J.F. Griffiths - 1900
Carroll, a recognized leader in the field of evolutionary development, to this new edition of Introduction to Genetic Analysis (IGA). The authors’ ambitious new plans for this edition focus on showing how genetics is practiced today. In particular, the new edition renews its emphasis on how genetic analysis can be a powerful tool for answering biological questions of all types.
Cradle
Arthur C. Clarke - 1987
After launch it mysteriously disappears. If it reaches civilian areas they'll be in big trouble. Carol Dawson, a journalist, is alerted by an unusual sight of whales in the Miami area & decides to write about it. Armed with equipment provided by her friend, Dr. Dale Michaels from the Miami Oceanographic Institute, she goes to investigate the rumors of a missing missile that could be behind the mysterious whale behavior. She hires the services of Nick Williams & Jefferson Troy, boat owners, so she can get to the Mexican Gulf to investigate. They find an unknown artifact. They have doubts about its nature, hoping it's part of a lost treasure. Old friends of Williams & Troy notice their discovery & want to steal it. In the story's background, the authors describe a submarine snake civilization on a planet called Canthor, & how they struggled to stay alive despite threats to their ecosystem. It's revealed that the artifact is actually a cradle that contains seeds with altered superhumans extracted from Earth millions of years ago & altered so they could live with other species--including the submarine snakes--on Earth. The spaceship that carries the cradle is manned by robots/cyborgs & has hidden itself on the ocean floor to make repairs. Dawson, Williams & Troy are asked to gather materials so the ship can be repaired & return to its mission. The ship...
Overkill: When Modern Medicine Goes Too Far
Paul A. Offit - 2020
Illnesses that once were a death sentence, such as HIV and certain forms of cancer, can now be managed, allowing those affected to live longer, healthier lives. Because of these advances, we now live 30 years longer than we did 100 years ago.In this game-changing book, Dr. Paul A. Offit debunks fifteen common medical interventions that have long been considered gospel despite mounting evidence of their adverse effects, from vitamins, sunscreen, fever-reducing medicines, and eyedrops for pink eye to more serious procedures like heart stents and knee surgery. Analyzing how these practices came to be, the biology of what makes them so ineffective and harmful, and the medical culture that continues to promote them, Overkill informs patients to help them advocate for their health. By educating ourselves, we can ask better questions about some of the drugs and surgeries that are all too readily available—and all too heavily promoted.
Perfection Unleashed
Jade Kerrion - 2012
One man seeks to embrace destiny, the other to escape it. Danyael Sabre spent sixteen years clawing out of the ruins of his childhood and finally has everything he wanted--a career, a home, and a trusted friend. To hold on to them, he keeps his head down and plays by the rules. An alpha empath, he is powerful in a world transformed by the Genetic Revolution, yet his experience has taught him to avoid attention.When the perfect human being, Galahad, escapes from Pioneer Laboratories, the illusory peace between humans and their derivatives--the in vitros, clones, and mutants--collapses into social upheaval. The abominations, deformed and distorted mirrors of humanity, created unintentionally in Pioneer Lab's search for perfection, descend upon Washington D.C. The first era of the Genetic Revolution was peaceful. The second is headed for open war.Although the genetic future of the human race pivots on Galahad, Danyael does not feel compelled to get involved and risk his cover of anonymity, until he finds out that the perfect human being looks just like him.
Genetic Rounds: A Doctor's Encounters in the Field that Revolutionized Medicine
Robert Marion - 2009
Robert Marion, whose bestselling book "The Intern Blues" is revered by doctors of all ages, offers a powerful and moving account of his experiences in modern genetics. His gripping stories illuminate a cutting-edge field of impossible moral complexities and incredible scientific breakthroughs that draw him deep into the lives of his patients and their families when they need him the most. Genetics is a specialty of secrets. After thirty years as a pediatric geneticist in New York City, Dr. Robert Marion knows things about his patients that their friends, their families, and even they themselves do not. Having access to this kind of inside information is at once a terrific honor and a terrible burden. It requires Dr. Marion to play detective, philosopher, physician, and friend, sometimes all over the course of a single visit.In "Genetic Rounds," he tells the surprising true stories of daily life as a clinical geneticist. From the girl whose bones break at the lightest touch to the boy who is unable to sweat, Dr. Marion imparts the life-long lessons he has learned from his most incredible cases. He walks us through perplexing medical puzzles that have sharpened his wit and transformed him into a Sherlock Holmes in his field. He shares ingenious practical insights that have changed his patients' lives. And he delves into the moral quandaries through which his patients in turn have changed his life: Should he wait until after Christmas to break bad news to a frightened family? Should he tell a close friend that his daughter may have a life-threatening, previously undiagnosed disease? And, most importantly, how can he persevere in a specialty that deals with so much heartbreak?The first book of its kind, "Genetic Rounds" is the story of a remarkable doctor in a field unlike any other. With unforgettable candor and compassion, Dr. Marion not only explores the human side of medicine: he shows what medicine can teach us about being human.""Genetic Rounds "is part medical detective story, part scientific tour de force, and part highly personal and emotional story of a doctor and the children and families who have shaped his career and his life in this fascinating field." --Perri Klass, MD, author of "Treatment Kind and Fair: Letters to a Young Doctor"From "Genetic Rounds""I've learned that in medicine, virtually anything is possible, that no matter how difficult or unlikely a situation might be, with hard work, perseverance, persistence, and the ability to work with people who are brilliant and creative, miracles can happen."Praise for "The Intern Blues""A candid . . . gripping account." --The New York Times Book Review"A thought-provoking study of real human beings." --Booklist"An important book for anyone contemplating the long, arduous task of becoming a doctor." --Library JournalPraise for "Learning to Play God""Clear, immediate and moving . . . provides as good a feel for the texture of medical training as any I've read." --The New York Times Book Review
The Genetic Lottery: Why DNA Matters for Social Equality
Kathryn Paige Harden - 2021
In recent years, scientists like Kathryn Paige Harden have shown that DNA makes us different, in our personalities and in our health--and in ways that matter for educational and economic success in our current society.In The Genetic Lottery, Harden introduces readers to the latest genetic science, dismantling dangerous ideas about racial superiority and challenging us to grapple with what equality really means in a world where people are born different. Weaving together personal stories with scientific evidence, Harden shows why our refusal to recognize the power of DNA perpetuates the myth of meritocracy, and argues that we must acknowledge the role of genetic luck if we are ever to create a fair society.Reclaiming genetic science from the legacy of eugenics, this groundbreaking book offers a bold new vision of a society where everyone thrives, regardless of how one fares in the genetic lottery.
Redesigning Humans: Choosing Our Genes, Changing Our Future
Gregory Stock - 2002
Gregory Stock, an expert on the implications of recent advances in reproductive biology, has glimpsed the inevitable future of biomedical engineering. Within decades, Stock asserts, technological advances will bring meaningful changes to our offspring; this scientific revolution promises to fundamentally alter the human species. With recent findings presented in a new afterword, Stock's provocative assessment cuts through the debate to envision an age of radical biotechnological advancement and unprecedented human choice.
Mercies in Disguise: A Story of Hope, a Family's Genetic Destiny, and the Science That Rescued Them
Gina Kolata - 2017
The doctor from California is on the line. "Are you ready Amanda?" The two people Amanda Baxley loves the most had begged her not to be tested--at least, not now. But she had to find out.If your family carried a mutated gene that foretold a brutal illness and you were offered the chance to find out if you'd inherited it, would you do it? Would you walk toward the problem, bravely accepting whatever answer came your way? Or would you avoid the potential bad news as long as possible? In Mercies in Disguise, acclaimed New York Times science reporter and bestselling author Gina Kolata tells the story of the Baxleys, an almost archetypal family in a small town in South Carolina. A proud and determined clan, many of them doctors, they are struck one by one with an inscrutable illness. They finally discover the cause of the disease after a remarkable sequence of events that many saw as providential. Meanwhile, science, progressing for a half a century along a parallel track, had handed the Baxleys a resolution--not a cure, but a blood test that would reveal who had the gene for the disease and who did not. And science would offer another dilemma--fertility specialists had created a way to spare the children through an expensive process. A work of narrative nonfiction in the tradition of the The Immortal Life of Henrietta Lacks, Mercies in Disguise is the story of a family that took matters into its own hands when the medical world abandoned them. It's a story of a family that had to deal with unspeakable tragedy and yet did not allow it to tear them apart. And it is the story of a young woman--Amanda Baxley--who faced the future head on, determined to find a way to disrupt her family's destiny.