We ignore this reality most of the time, but when a new threat (Ebola, SARS, Zika) seems imminent, we send our best and bravest doctors to contain it--people like Dr. Ali S. Khan.In his long career as a public health first responder—protected by a thin mask from infected patients, napping under nets to keep out scorpions, making life-and-death decisions on limited, suspect information—Khan has found that rogue microbes will always be a problem, but outbreaks are often caused by people. We make mistakes, politicize emergencies, and, too often, fail to imagine the consequences of our actions.The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others and how we could do more to prevent their return. It's both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    #1 New York Times bestselling author Cokie Roberts brings us women who fought the Revolution as valiantly as the men, often defending their very doorsteps. Drawing upon personal correspondence, private journals, and even favoured recipes, Roberts reveals the often surprising stories of these fascinating women, bringing to life the everyday trials and extraordinary triumphs of individuals like Abigail Adams, Mercy Otis Warren, Deborah Read Franklin, Eliza Pinckney, Catherine Littlefield Green, Esther DeBerdt Reed and Martha Washington–proving that without our exemplary women, the new country might have never survived.

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    C. J. Peters was on the front lines of our biological battle against “hot” viruses around the world. In the course of that career, he learned countless lessons about our interspecies turf wars with infectious agents. Called in to contain an outbreak of deadly hemorrhagic fever in Bolivia, he confronted the despair of trying to save a colleague who accidentally infected himself with an errant scalpel. Working in Level 4 labs on the Machupo and Ebola viruses, he saw time and again why expensive high-tech biohazard containment equipment is only as safe as the people who use it.   Because of new, emerging viruses, and the return of old, “vanquished” ones for which vaccines do not exist, there remains a very real danger of a new epidemic that could, without proper surveillance and early intervention, spread worldwide virtually overnight. And the possibility of foreign countries or terrorist groups using deadly airborne viruses—the poor man’s nuclear arsenal—looms larger than ever.   High-octane science writing at its best and most revealing, Virus Hunter is a thrilling first-person account of what it is like to be a warrior in the Hot Zone.

    Emma Edmonds cut off her hair and assumed the identity of a man to enlist as a Union private, witnessing the bloodiest battles of the Civil War. The beautiful widow, Rose O’Neale Greenhow, engaged in affairs with powerful Northern politicians to gather intelligence for the Confederacy, and used her young daughter to send information to Southern generals. Elizabeth Van Lew, a wealthy Richmond abolitionist, hid behind her proper Southern manners as she orchestrated a far-reaching espionage ring, right under the noses of suspicious rebel detectives.Using a wealth of primary source material and interviews with the spies’ descendants, Abbott seamlessly weaves the adventures of these four heroines throughout the tumultuous years of the war. With a cast of real-life characters including Walt Whitman, Nathaniel Hawthorne, General Stonewall Jackson, detective Allan Pinkerton, Abraham and Mary Todd Lincoln, and Emperor Napoleon III, Liar, Temptress, Soldier, Spy draws you into the war as these daring women lived it.Liar, Temptress, Soldier, Spy contains 39 black & white photos and 3 maps.

    Bell ruling made government sterilization of "undesirable" citizens the law of the land. New York Times bestselling author Adam Cohen tells the story in Imbeciles of one of the darkest moments in the American legal tradition: the Supreme Court's decision to champion eugenic sterilization for the greater good of the country. In 1927, when the nation was caught up in eugenic fervor, the justices allowed Virginia to sterilize Carrie Buck, a perfectly normal young woman, for being an "imbecile." It is a story with many villains, from the superintendent of the Dickensian Virginia Colony for Epileptics and Feebleminded who chose Carrie for sterilization to the former Missouri agriculture professor and Nazi sympathizer who was the nation's leading advocate for eugenic sterilization. But the most troubling actors of all were the eight Supreme Court justices who were in the majority--including William Howard Taft, the former president; Louis Brandeis, the legendary progressive; and Oliver Wendell Holmes, Jr., America's most esteemed justice, who wrote the decision urging the nation to embark on a program of mass eugenic sterilization

    Mankind's battle to stay alive and healthy for as long as possible is our oldest, most universal struggle. With his characteristic wit and vastly informed historical scope, Roy Porter examines the war fought between disease and doctors on the battleground of the flesh from ancient times to the present. He explores the many ingenious ways in which we have attempted to overcome disease through the ages: the changing role of doctors, from ancient healers, apothecaries, and blood-letters to today's professionals; the array of drugs, from Ayurvedic remedies to the launch of Viagra; the advances in surgery, from amputations performed by barbers without anesthetic to today's sophisticated transplants; and the transformation of hospitals from Christian places of convalescence to modern medical powerhouses. Cleverly illustrated with historic line drawings, the chronic ailments of humanity provide vivid anecdotes for Porter's enlightening story of medicine's efforts to prevail over a formidable and ever-changing adversary.

    Making use of an astonishing cache of little-studied material, including documents, objects, and portraits only just discovered, Jill Lepore brings Jane Franklin to life in a way that illuminates not only this one extraordinary woman but an entire world. Lepore's life of Jane Franklin, with its strikingly original vantage on Benjamin Franklin, is at once a wholly different account of the founding and one of the great untold stories of American history and letters.

    In his capital at Constantinople he built the world's most beautiful building, married its most powerful empress, and wrote its most enduring legal code, seemingly restoring Rome's fortunes for the next five hundred years. Then, in the summer of 542, he encountered a flea. The ensuing outbreak of bubonic plague killed five thousand people a day in Constantinople and nearly killed Justinian himself. In Justinian's Flea, William Rosen tells the story of history's first pandemic plague seven centuries before the Black Death that killed tens of millions, devastated the empires of Persia and Rome, left a path of victims from Ireland to Iraq, and opened the way for the armies of Islam. Weaving together evolutionary microbiology, economics, military strategy, ecology, and ancient and modern medicine, Rosen offers a sweeping narrative of one of the great hinge moments in history, one that will appeal to readers of John Kelly's The Great Mortality, John Barry's The Great Influenza, and Jared Diamond's Collapse .

    Patriots celebrated their departure and the confirmation of U.S. independence. But for tens of thousands of American loyalists, the British evacuation spelled worry, not jubilation. What would happen to them in the new United States? Would they and their families be safe? Facing grave doubts about their futures, some sixty thousand loyalists—one in forty members of the American population—decided to leave their homes and become refugees elsewhere in the British Empire. They sailed for Britain, for Canada, for Jamaica, and for the Bahamas; some ventured as far as Sierra Leone and India. Wherever they went, the voyage out of America was a fresh beginning, and it carried them into a dynamic if uncertain new world.A groundbreaking history of the revolutionary era, Liberty’s Exiles tells the story of this remarkable global diaspora. Through painstaking archival research and vivid storytelling, award-winning historian Maya Jasanoff re-creates the journeys of ordinary individuals whose lives were overturned by extraordinary events. She tells of refugees like Elizabeth Johnston, a young mother from Georgia, who spent nearly thirty years as a migrant, searching for a home in Britain, Jamaica, and Canada. And of David George, a black preacher born into slavery, who found freedom and faith in the British Empire, and eventually led his followers to seek a new Jerusalem in Sierra Leone. Mohawk leader Joseph Brant resettled his people under British protection in Ontario, while the adventurer William Augustus Bowles tried to shape a loyalist Creek state in Florida. For all these people and more, it was the British Empire—not the United States—that held the promise of “life, liberty, and the pursuit of happiness.” Yet as they dispersed across the empire, the loyalists also carried things from their former homes, revealing an enduring American influence on the wider British world.Ambitious, original, and personality-filled, Liberty’s Exiles is at once an intimate narrative history and a provocative new analysis—a book that explores an unknown dimension of America’s founding to illuminate the meanings of liberty itself.

    Horrifyingly violent Indian attacks had all but emptied the northern frontier of settlers, and many traumatized refugees—including the main accusers of witches—had fled to communities like Salem. Meanwhile the colony’s leaders, defensive about their own failure to protect the frontier, pondered how God’s people could be suffering at the hands of savages. Struck by the similarities between what the refugees had witnessed and what the witchcraft “victims” described, many were quick to see a vast conspiracy of the Devil (in league with the French and the Indians) threatening New England on all sides. By providing this essential context to the famous events, and by casting her net well beyond the borders of Salem itself, Norton sheds new light on one of the most perplexing and fascinating periods in our history.

    Drawing on the diaries of a midwife and healer in eighteenth-century Maine, this intimate history illuminates the medical practices, household economies, religious rivalries, and sexual mores of the New England frontier.

    In this groundbreaking history, Carol Berkin shows us how women played a vital role throughout the conflict.The women of the Revolution were most active at home, organizing boycotts of British goods, raising funds for the fledgling nation, and managing the family business while struggling to maintain a modicum of normalcy as husbands, brothers and fathers died. Yet Berkin also reveals that it was not just the men who fought on the front lines, as in the story of Margaret Corbin, who was crippled for life when she took her husband’s place beside a cannon at Fort Monmouth. This incisive and comprehensive history illuminates a fascinating and unknown side of the struggle for American independence.