Between 1900 and 1907, she infected twenty-two New Yorkers with typhoid fever through her puddings and cakes; one of them died. Tracked down through epidemiological detective work, she was finally apprehended as she hid behind a barricade of trashcans. To protect the public's health, authorities isolated her on Manhattan's North Brother Island, where she died some thirty years later.This book tells the remarkable story of Mary Mallon--the real Typhoid Mary. Combining social history with biography, historian Judith Leavitt re-creates early-twentieth-century New York City, a world of strict class divisions and prejudice against immigrants and women. Leavitt engages the reader with the excitement of the early days of microbiology and brings to life the conflicting perspectives of journalists, public health officials, the law, and Mary Mallon herself.Leavitt's readable account illuminates dilemmas that continue to haunt us. To what degree are we willing to sacrifice individual liberty to protect the public's health? How far should we go in the age of AIDS, drug-resistant tuberculosis, and other diseases? For anyone who is concerned about the threats and quandaries posed by new epidemics, Typhoid Mary is a vivid reminder of the human side of disease and disease control.

    Villagers--mainly young women--suffered from unseen torments that caused them to writhe, shriek, and contort their bodies, complaining of pins stuck into their flesh and of being haunted by specters. Believing that they suffered from assaults by an invisible spirit, the community began a hunt to track down those responsible for the demonic work. The resulting Salem Witch Trials, culminating in the execution of 19 villagers, persists as one of the most mysterious and fascinating events in American history. Historians have speculated on a web of possible causes for the witchcraft that stated in Salem and spread across the region-religious crisis, ergot poisoning, an encephalitis outbreak, frontier war hysteria--but most agree that there was no single factor. Rather, as Emerson Baker illustrates in this seminal new work, Salem was "a perfect storm": a unique convergence of conditions and events that produced something extraordinary throughout New England in 1692 and the following years, and which has haunted us ever since. Baker shows how a range of factors in the Bay colony in the 1690s, including a new charter and government, a lethal frontier war, and religious and political conflicts, set the stage for the dramatic events in Salem. Engaging a range of perspectives, he looks at the key players in the outbreak--the accused witches and the people they allegedly bewitched, as well as the judges and government officials who prosecuted them--and wrestles with questions about why the Salem tragedy unfolded as it did, and why it has become an enduring legacy. Salem in 1692 was a critical moment for the fading Puritan government of Massachusetts Bay, whose attempts to suppress the story of the trials and erase them from memory only fueled the popular imagination. Baker argues that the trials marked a turning point in colonial history from Puritan communalism to Yankee independence, from faith in collective conscience to skepticism toward moral governance. A brilliantly told tale, A Storm of Witchcraft also puts Salem's storm into its broader context as a part of the ongoing narrative of American history and the history of the Atlantic World.

    From the world’s most painful hornet, to the flies that transmit deadly diseases, to millipedes that stop traffic, to the “bookworms” that devour libraries, to the Japanese beetles munching on your roses, Wicked Bugs delves into the extraordinary powers of many-legged creatures. With wit, style, and exacting research, Stewart has uncovered the most terrifying and titillating stories of bugs gone wild. It’s an A to Z of insect enemies, interspersed with sections that explore bugs with kinky sex lives (“She’s Just Not That Into You”), creatures lurking in the cupboard (“Fear No Weevil”), insects eating your tomatoes (“Gardener’s Dirty Dozen”), and phobias that feed our (sometimes) irrational responses to bugs (“Have No Fear”). Intricate and strangely beautiful etchings and drawings by Briony Morrow-Cribbs capture diabolical bugs of all shapes and sizes in this mixture of history, science, murder, and intrigue that begins—but doesn’t end—in your own backyard.

    Benjamin Franklin, perhaps the pivotal figure in colonial and revolutionary America, comes vividly to life in this masterly biography.Wit, diplomat, scientist, philosopher, businessman, inventor, and bon vivant, Benjamin Franklin was in every respect America’s first Renaissance man. From penniless runaway to highly successful printer, from ardently loyal subject of Britain to architect of an alliance with France that ensured America’s independence, Franklin went from obscurity to become one of the world’s most admired figures, whose circle included the likes of Voltaire, Hume, Burke, and Kant. Drawing on previously unpublished letters and a host of other sources, acclaimed historian H. W. Brands has written a thoroughly engaging biography of the eighteenth-century genius. A much needed reminder of Franklin’s greatness and humanity, The First American is a work of meticulous scholarship that provides a magnificent tour of a legendary historical figure, a vital era in American life, and the countless arenas in which the protean Franklin left his legacy.

    But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers--resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    Instead, they found disease, hunger, and hostile natives. Ill prepared for such hardship, the men responded with incompetence and infighting; only the leadership of Captain John Smith averted doom for the first permanent English settlement in the New World.The Jamestown colony is one of the great survival stories of American history, and this book brings it fully to life for the first time. Drawing on extensive original documents, David A. Price paints intimate portraits of the major figures from the formidable monarch Chief Powhatan, to the resourceful but unpopular leader John Smith, to the spirited Pocahontas, who twice saved Smith’s life. He also gives a rare balanced view of relations between the settlers and the natives and debunks popular myths about the colony. This is a superb work of history, reminding us of the horrors and heroism that marked the dawning of our nation.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Over fifty incredible years at the heart of the Age of Revolution, he fought courageously on both sides of the Atlantic. He was a soldier, statesman, idealist, philanthropist, and abolitionist. As a teenager, Lafayette ran away from France to join the American Revolution. Returning home a national hero, he helped launch the French Revolution, eventually spending five years locked in dungeon prisons. After his release, Lafayette sparred with Napoleon, joined an underground conspiracy to overthrow King Louis XVIII, and became an international symbol of liberty. Finally, as a revered elder statesman, he was instrumental in the overthrow of the Bourbon Dynasty in the Revolution of 1830. From enthusiastic youth to world-weary old age, from the pinnacle of glory to the depths of despair, Lafayette never stopped fighting for the rights of all mankind. His remarkable life is the story of where we come from, and an inspiration to defend the ideals he held dear.

    Drawing on momentous (yet dimly remembered) historical epidemics, contemporary analyses, and cutting-edge research from a range of scientific disciplines, bestselling author, physician, sociologist, and public health expert Nicholas A. Christakis explores what it means to live in a time of plague—an experience that is paradoxically uncommon to the vast majority of humans who are alive, yet deeply fundamental to our species.Unleashing new divisions in our society as well as opportunities for cooperation, this 21st-century pandemic has upended our lives in ways that will test, but not vanquish, our already frayed collective culture. Featuring new, provocative arguments and vivid examples ranging across medicine, history, sociology, epidemiology, data science, and genetics, Apollo's Arrow envisions what happens when the great force of a deadly germ meets the enduring reality of our evolved social nature.

    Brenda Maddox tells a powerful story of a remarkably single-minded, forthright, and tempestuous young woman who, at the age of fifteen, decided she was going to be a scientist, but who was airbrushed out of the greatest scientific discovery of the twentieth century.

    But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong.Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

    Moving up the Mississippi River in the late summer, in the span of just a few months the fever killed more than eighteen thousand people. The city of Memphis, Tennessee, was particularly hard hit: Of the approximately twenty thousand who didn’t flee the city, seventeen thousand contracted the fever, and more than five thousand died—the equivalent of a million New Yorkers dying in an epidemic today.Fever Season chronicles the drama in Memphis from the outbreak in August until the disease ran its course in late October. The story that Jeanette Keith uncovered is a profound–and never more relevant–account of how a catastrophe inspired reactions both heroic and cowardly. Some ministers, politicians, and police fled their constituents, while prostitutes and the poor risked their lives to nurse the sick. Using the vivid, anguished accounts and diaries of those who chose to stay and those who were left behind, Fever Season depicts the events of that summer and fall. In its pages we meet people of great courage and compassion, many of whom died for having those virtues. We also learn how a disaster can shape the future of a city.

    Davis, author of the phenomenal New York Times bestseller Don't Know Much About History, presents a collection of extraordinary stories, each detailing an overlooked episode that shaped the nation's destiny and character. Davis's dramatic narratives set the record straight, busting myths and bringing to light little-known but fascinating facts from a time when the nation's fate hung in the balance.Spanning a period from the Spanish arrival in America to George Washington's inauguration in 1789, America's Hidden History details these episodes, among others:The story of the first real Pilgrims in America, who were wine-making French Huguenots, not dour English SeparatistsThe coming-of-age story of Queen Isabella, who suggested that Columbus pack the moving mess hall of pigs that may have spread disease to many Native AmericansThe long, bloody relationship between the Pilgrims and Indians that runs counter to the idyllic scene of the Thanksgiving feastThe little-known story of George Washington as a headstrong young soldier who committed a war crime, signed a confession, and started a war!Full of color, intrigue, and human interest, America's Hidden History is an iconoclastic look at America's past, connecting some of the dots between history and today's headlines, proving why Davis is truly America's Teacher.

    A national bestseller in hardcover for more than a year after its initial publication, it has sold almost four million copies and has been translated into seventeen languages. For this elegant thirtieth-anniversary edition—published in both hardcover and paperback—Brown has contributed an incisive new preface.Using council records, autobiographies, and firsthand descriptions, Brown allows the great chiefs and warriors of the Dakota, Ute, Sioux, Cheyenne, and other tribes to tell us in their own words of the battles, massacres, and broken treaties that finally left them demoralized and defeated. A unique and disturbing narrative told with force and clarity, Bury My Heart at Wounded Knee changed forever our vision of how the West was really won.