The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    In this pocket version of his bestselling Life Without Diabetes, Professor Roy Taylor offers a brilliantly concise explanation of what happens to us when we get type 2 and how we can escape it.Taylor's research has demonstrated that type 2 is caused by just one factor - too much internal fat in the liver and pancreas - and that to reverse it you need to strip this harmful internal fat out with rapid weight loss.In simple, accessible language, Taylor takes you through the three steps of his clinically proven Newcastle weight loss plan and shows how to incorporate the programme into your life.Complete with FAQs and inspirational tips from his trial participants, this is an essential read for anyone who has been given a diagnosis of type 2 diabetes or pre-diabetes and wants to understand their condition and transform their outcomes.

    While they're at it, they helpfully demystify many complicated things we do know about, from quarks and neutrinos to gravitational waves and exploding black holes. With equal doses of humor and delight, they invite us to see the universe as a vast expanse of mostly uncharted territory that's still ours to explore.This entertaining illustrated science primer is the perfect book for anyone who's curious about all the big questions physicists are still trying to answer.

    A playful, entertaining, and mind-bending introduction to modern physics, it's already a major bestseller in Italy and the United Kingdom. Carlo Rovelli offers surprising—and surprisingly easy to grasp—explanations of general relativity, quantum mechanics, elementary particles, gravity, black holes, the complex architecture of the universe, and the role humans play in this weird and wonderful world. He takes us to the frontiers of our knowledge: to the most minute reaches of the fabric of space, back to the origins of the cosmos, and into the workings of our minds. “Here, on the edge of what we know, in contact with the ocean of the unknown, shines the mystery and the beauty of the world,” Rovelli writes. “And it’s breathtaking.”

    Yet in The Science of Interstellar, Kip Thorne, the physicist who assisted Nolan on the scientific aspects of Interstellar, shows us that the movie’s jaw-dropping events and stunning, never-before-attempted visuals are grounded in real science. Thorne shares his experiences working as the science adviser on the film and then moves on to the science itself. In chapters on wormholes, black holes, interstellar travel, and much more, Thorne’s scientific insights—many of them triggered during the actual scripting and shooting of Interstellar—describe the physical laws that govern our universe and the truly astounding phenomena that those laws make possible.Interstellar and all related characters and elements are trademarks of and © Warner Bros. Entertainment Inc. (s14).

    Packed with powerful, fast-acting techniques – including a novel routine to get any class quiet in 15 seconds or less – this book helps teachers across all age groups connect and succeed with hard-to-reach, reluctant learners.  You’ll d iscover: The simple six-step plan to minimise & deal with classroom behaviour problems How to gain trust & respect from tough, hard-to-reach students How to put an end to power struggles & confrontation How to have students follow your instructions… with no need to repeat yourself The crucial importance of consistency (and how to achieve it) Quick and easy ways to raise engagement and enjoyment in your lessons The ‘Clean Slate’ – a step by step method you can use to ‘start over’ with that particularly difficult group of students who won’t do anything you say. Take Control of the Noisy Class provides hundreds of practical ideas and interventions to end your classroom management struggles & create a thoroughly enjoyable lesson climate for all concerned.

    In this book—the only one on the market dealing with the specific issues involved in toilet training children with autism—Maria Wheeler offers a detailed roadmap for success, based on over twenty years of experience. Easy-to-read bulleted lists offer over 200 do’s and don’ts, along with more than fifty real-life examples. Learn, among other things, how to:gauge “readiness" overcome fear of the bathroom teach how to use toilet paper, flush and wash up and deal with toileting in unfamiliar environments. A life preserver for parents and reluctant children!Helpful chapters include:The Importance of Toilet Training Determining Readiness Developing a Toileting Routine Dressing for the Occasion Habit Training Teaching Continence Communicating the Need to Use the Toilet When Toilet Training is Successful Toileting in Unfamiliar Environments Nighttime Training Support Strategies Common Problems (and Solutions) Associated with Toilet Training Persons with Autism

    How does Jane Goodall’s relationship with her dog Rusty inform her thinking about our relationship to other species? Which time and place would Jared Diamond most prefer to live in, in light of his work on the role of chance in history? What does driving a sports car have to do with Steven Weinberg’s quest for the “theory of everything”? Physicist and journalist Stefan Klein’s intimate conversations with nineteen of the world’s best-known scientists (including three Nobel Laureates) let us listen in as they talk about their paradigm-changing work—and how it is deeply rooted in their daily lives. • Cosmologist Martin Rees on the beginning and end of the world • Evolutionary biologist Richard Dawkins on egoism and selflessness • Neuroscientist V. S. Ramachandran on consciousness • Molecular biologist Elizabeth Blackburn on aging • Philosopher Peter Singer on morality • Physician and social scientist Nicholas Christakis on human relationships • Biochemist Craig Venter on the human genome • Chemist and poet Roald Hoffmann on beauty

    You'll learn how to overcome the unique issues that confront nighttime photographers and capture images of which you'll be proud. Co-author Jennifer Wu, an elite Canon "Explorer of Light" professional photographer, has become renowned for her ability to capture nighttime phenomena, from quarter-phase moon rises to shooting stars to the ephemeral Milky Way. this new guide reveals her methods and concentrates on photographing four principal subjects: stars as points of light, star trails, the moon, and twilight. these subjects share common photo techniques and considerations, but each also requires a distinct approach. Once captured, your digital images must be fi nished on the computer; coauthor and author of the bestselling Photography: Outdoors, James Martin, delves into the settings and procedures that elevate an image from mundane to striking. This clear and practical guide will help photographers of all levels portray the stunning spectacle of the night sky, preserving those special memories and moments from a life outdoors.

    In the book, Sagan explores 15 billion years of cosmic evolution and the development of science and civilization. Cosmos traces the origins of knowledge and the scientific method, mixing science and philosophy, and speculates to the future of science. The book also discusses the underlying premises of science by providing biographical anecdotes about many prominent scientists throughout history, placing their contributions into the broader context of the development of modern science.The book covers a broad range of topics, comprising Sagan's reflections on anthropological, cosmological, biological, historical, and astronomical matters from antiquity to contemporary times. Sagan reiterates his position on extraterrestrial life—that the magnitude of the universe permits the existence of thousands of alien civilizations, but no credible evidence exists to demonstrate that such life has ever visited earth.

    Global warming and associated climate change exists - but the role of humans in that change is entirely debatable. A little-known aspect of modern climate science is that the warming of the global atmosphere-ocean system over the last 100 years, even if entirely human-caused, has progressed at a rate that reduces the threat of future warming by 50% compared to the climate model projections. To the extent warming is partly natural (a possibility even the IPCC acknowledges), the future threat is reduced even further. This, by itself, should be part of the debate over energy policy – but it isn’t. Why? The news media, politicians, bureaucrats, rent-seekers, government funding agencies, and a “scientific-technological elite” (as President Eisenhower called it) have collaborated to spread what amounts to fake climate news. Exaggerated climate claims appear on a daily basis, sucking the air out of more reasoned discussions of the scientific evidence which are too boring for a populace increasingly addicted to climate change porn. Upon close examination it is found that the "97% of climate scientists agree" meme is inaccurate, misleading, and useless for decision-making; human causation of warming is simply assumed by the vast majority of climate researchers. In contrast to what many have been taught, there have been no obvious changes in severe weather, including hurricanes, tornadoes, droughts or floods. Despite an active 2018 wildfire season, there has actually been a long-term decrease in wildfire activity, although that will change if forest management practices are not implemented. Proxy evidence of past temperature and Arctic sea ice changes suggest warming and sea ice decline over the last 50 years or so is not out of the ordinary, and partly or even mostly natural. The Antarctic ice sheet isn't collapsing, but remains stable. The human component of sea level rise is shown to be, at most, only 1 inch per 30 years (25% of the observed rate of rise); and the latest evidence is that more CO2 dissolved in ocean water will be good for marine life, not harmful. Admittedly, continued emissions of CO2 from fossil fuel burning can be expected to cause (and probably has caused) some of our recent warming. But the Paris Agreement, even if extended through the end of the 21st Century, will have no measurable effect on global temperatures because the governments of the world realize humanity will depend upon fossil fuels for decades to come. Despite news reports and politicians' proclamations, international agreements to reduce CO2 emissions are all economic pain for no observable climate gain. What government-mandated reliance on expensive and impractical energy sources will do is increase energy poverty, and poverty kills. This downside to illusory efforts to “Save the Earth” is already being experienced in the UK and elsewhere. If people are genuinely concerned about humanity thriving, they must reject global warming alarmism. In terms of environmental regulation, the end result of the U.S. EPA's Endangerment Finding will be reduced prosperity for all, and climate gain for none. The good news is that there is no global warming crisis, and this book will inform citizens and help guide governments toward decisions which benefit the most people while doing the least harm.

    Then, in 2005, astronomer Mike Brown made the discovery of a lifetime: a tenth planet, Eris, slightly bigger than Pluto. But instead of its resulting in one more planet being added to our solar system, Brown’s find ignited a firestorm of controversy that riled the usually sedate world of astronomy and launched him into the public eye. The debate culminated in the demotion of Pluto from real planet to the newly coined category of “dwarf” planet. Suddenly Brown was receiving hate mail from schoolchildren and being bombarded by TV reporters—all because of the discovery he had spent years searching for and a lifetime dreaming about.Filled with both humor and drama, How I Killed Pluto and Why It Had It Coming is Mike Brown’s engaging first-person account of the most tumultuous year in modern astronomy—which he inadvertently caused. As it guides readers through important scientific concepts and inspires us to think more deeply about our place in the cosmos, it is also an entertaining and enlightening personal story: While Brown sought to expand our understanding of the vast nature of space, his own life was changed in the most immediate, human ways by love, birth, and death. A heartfelt and personal perspective on the demotion of everyone’s favorite farflung planet, How I Killed Pluto and Why It Had It Coming is the book for anyone, young or old, who has ever dreamed of exploring the universe—and who among us hasn’t?

    Having just completed his masterpiece, The General Theory of Relativity—which provided a brand-new theory of gravity and promised a new perspective on the cosmos as a whole—he set out at once to share his excitement with as wide a public as possible in this popular and accessible book.Here published for the first time as a Penguin Classic, this edition of Relativity features a new introduction by bestselling science author Nigel Calder.

    This new edition continues to offer the most complete technology/new media support package available. That technology/new media package includes: Interactives, Animations, and introducing Connect - online homework and course management.

    Readers will develop an understanding of the multiple research methods and strategies used in education and related fields, the ability to read and critically evaluate published research, and the ability to write a proposal, construct a questionnaire, and conduct an empirical research study on their own.