These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Little did they know that their next roles, in a new science-fiction television series, would shape their lives in ways no one could have anticipated. In seventy-nine television episodes and six feature films, they grew to know each other more than most friends could ever imagine.Over the course of half a century, Shatner and Nimoy saw each other through personal and professional highs and lows. In this powerfully emotional book, Shatner tells the story of a man who was his friend for five decades, recounting anecdotes and untold stories of their lives on and off set, as well as gathering stories from others who knew Nimoy well, to present a full picture of a rich life.As much a biography of Nimoy as a story of their friendship, Leonard is a uniquely heartfelt book written by one legendary actor in celebration of another.

    In The Master Algorithm, Pedro Domingos lifts the veil to give us a peek inside the learning machines that power Google, Amazon, and your smartphone. He assembles a blueprint for the future universal learner--the Master Algorithm--and discusses what it will mean for business, science, and society. If data-ism is today's philosophy, this book is its bible.

    An inventive blend of autobiography, science writing, philosophy, and advice, this book tells the wild story of his personal and professional life as a scientist, from his childhood in the UFO territory of New Mexico, to the loss of his mother, the founding of the first start-up, and finally becoming a world-renowned technological guru. Understanding virtual reality as being both a scientific and cultural adventure, Lanier demonstrates it to be a humanistic setting for technology. While his previous books offered a more critical view of social media and other manifestations of technology, in this book he argues that virtual reality can actually make our lives richer and fuller. Dawn of the New Everything is ultimately a look at what it means to be human at a moment of unprecedented technological possibility, giving readers a new perspective on how the brain and body connect to the world.

    But more than this, there was gravity. After that, all hell broke loose… In A Universe from Nothing, Krauss revealed how our entire universe could arise from nothing. Now, he reveals what that something—reality—is. And, reality is not what we think or sense—it’s weird, wild, and counterintuitive; it’s hidden beneath everyday experience; and its inner workings seem even stranger than the idea that something can come from nothing. In a landmark, unprecedented work of scientific history, Krauss leads us to the furthest reaches of space and time, to scales so small they are invisible to microscopes, to the birth and rebirth of light, and into the natural forces that govern our existence. His unique blend of rigorous research and engaging storytelling invites us into the lives and minds of the remarkable, creative scientists who have helped to unravel the unexpected fabric of reality—with reason rather than superstition and dogma. Krauss has himself been an active participant in this effort, and he knows many of them well. The Greatest Story challenges us to re-envision ourselves and our place within the universe, as it appears that “God” does play dice with the universe. In the incisive style of his scintillating essays for The New Yorker, Krauss celebrates the greatest intellectual adventure ever undertaken—to understand why we are here in a universe where fact is stranger than fiction.

    Across the globe, we sat riveted to television and computer screens as journalists flocked to the Atacama desert. While we saw what transpired above ground during the grueling and protracted rescue, the story of the miners experiences below the earths surface and the lives that led them there hasn't been heard until now. In this master work of a Pulitzer Prizewinning journalist, Hctor Tobar gains exclusive access to the miners and their stories. The result is a miraculous and emotionally textured account of the thirty-three men who came to think of the San José mine as a kind of coffin, as a cave inflicting constant and thundering aural torment, and as a church where they sought redemption through prayer while the world watched from above. It offers an understanding of the families and personal histories that brought los 33 to the mine, and the mystical and spiritual elements that surrounded working in such a dangerous place.

    In the next ten years, change will happen even faster. As Hillary Clinton's Senior Advisor for Innovation, Alec Ross travelled nearly a million miles to forty-one countries, the equivalent of two round-trips to the moon. From refugee camps in the Congo and Syrian war zones, to visiting the world's most powerful people in business and government, Ross's travels amounted to a four-year masterclass in the changing nature of innovation. In The Industries of the Future, Ross distils his observations on the forces that are changing the world. He highlights the best opportunities for progress and explains how countries thrive or sputter. Ross examines the specific fields that will most shape our economic future over the next ten years, including robotics, artificial intelligence, the commercialization of genomics, cybercrime and the impact of digital technology. Blending storytelling and economic analysis, he answers questions on how we will need to adapt. Ross gives readers a vivid and informed perspective on how sweeping global trends are affecting the ways we live, now and tomorrow.

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    A team of journalists with unparalleled inside access provides the first full, in-depth account of WikiLeaks, its founder Julian Assange, and the ethical, legal, and political controversies it has both uncovered and provoked.

    Gates says, "we can work on a local, national, and global level to build the technologies, businesses, and industries to avoid the worst impacts of climate change." His interest in climate change is a natural outgrowth of the efforts by his foundation to reduce poverty and disease. Climate change, according to Gates, will have the biggest impact on the people who have done the least to cause it. As a technologist, he has seen first-hand how innovation can change the world. By investing in research, inventing new technologies, and by deploying them quickly at large scale, Gates believes climate change can be addressed in meaningful ways. According to Gates, "to prevent the worst effects of climate change, we have to get to net-zero emissions of greenhouse gases. This problem is urgent, and the debate is complex, but I believe we can come together to invent new carbon-zero technologies, deploy the ones we have, and ultimately avoid a climate catastrophe."

    But Cullen was no mercy killer, nor was he a simple monster. He was a favorite son, husband, beloved father, best friend, and celebrated caregiver. Implicated in the deaths of as many as 300 patients, he was also perhaps the most prolific serial killer in American history.Cullen's murderous career in the world's most trusted profession spanned sixteen years and nine hospitals across New Jersey and Pennsylvania. When, in March of 2006, Charles Cullen was marched from his final sentencing in an Allentown, Pennsylvania, courthouse into a waiting police van, it seemed certain that the chilling secrets of his life, career, and capture would disappear with him. Now, in a riveting piece of investigative journalism nearly ten years in the making, journalist Charles Graeber presents the whole story for the first time. Based on hundreds of pages of previously unseen police records, interviews, wire-tap recordings and videotapes, as well as exclusive jailhouse conversations with Cullen himself and the confidential informant who helped bring him down, THE GOOD NURSE weaves an urgent, terrifying tale of murder, friendship, and betrayal.Graeber's portrait of Cullen depicts a surprisingly intelligent and complicated young man whose promising career was overwhelmed by his compulsion to kill, and whose shy demeanor masked a twisted interior life hidden even to his family and friends. Were it not for the hardboiled, unrelenting work of two former Newark homicide detectives racing to put together the pieces of Cullen's professional past, and a fellow nurse willing to put everything at risk, including her job and the safety of her children, there's no telling how many more lives could have been lost.In the tradition of In Cold Blood, THE GOOD NURSE does more than chronicle Cullen's deadly career and the breathless efforts to stop him; it paints an incredibly vivid portrait of madness and offers a penetrating look inside America's medical system. Harrowing and irresistibly paced, this book will make you look at medicine, hospitals, and the people who work in them, in an entirely different way.

    How has Google done it? Veteran technology reporter Steven Levy was granted unprecedented access to the company, and in this revelatory book he takes readers inside Google headquarters—the Googleplex—to show how Google works.While they were still students at Stanford, Google cofounders Larry Page and Sergey Brin revolutionized Internet search. They followed this brilliant innovation with another, as two of Google’s earliest employees found a way to do what no one else had: make billions of dollars from Internet advertising. With this cash cow, Google was able to expand dramatically and take on other transformative projects: more efficient data centers, open-source cell phones, free Internet video (YouTube), cloud computing, digitizing books, and much more.The key to Google’s success in all these businesses, Levy reveals, is its engineering mind-set and adoption of such Internet values as speed, openness, experimentation, and risk taking. After its unapologetically elitist approach to hiring, Google pampers its engineers—free food and dry cleaning, on-site doctors and masseuses—and gives them all the resources they need to succeed. Even today, with a workforce of more than 23,000, Larry Page signs off on every hire.But has Google lost its innovative edge? With its newest initiative, social networking, Google is chasing a successful competitor for the first time. Some employees are leaving the company for smaller, nimbler start-ups. Can the company that famously decided not to be evil still compete?No other book has ever turned Google inside out as Levy does with In the Plex.

    In this riveting work of true crime, he spotlights four of the most diabolical criminals he’s confronted, interviewed and learned from. Going deep into each man’s life and crimes, he outlines the factors that led them to murder and how he used his interrogation skills to expose their means, motives, and true evil. Like the hit Netflix show, The Killer Across the Table is centered around Douglas’ unique interrogation and profiling process. With his longtime collaborator Mark Olshaker, Douglas recounts the chilling encounters with these four killers as he experienced them—revealing for the first time his profile methods in detail. Going step by step through his interviews, Douglas explains how he connects each killer’s crimes to the specific conversation, and contrasts these encounters with those of other deadly criminals to show what he learns from each one. In the process, he returns to other famous cases, killers and interviews that have shaped his career, describing how the knowledge he gained from those exchanges helped prepare him for these.A glimpse into the mind of a man who has pierced the heart of human darkness, The Killer Across the Table unlocks the ultimate mystery of depravity and the techniques and approaches that have countered evil in the name of justice.

    Stargazing is a pursuit that continues to fascinate us: from Copernicus to Carl Sagan, astronomers throughout history have spent their lives trying to answer the biggest questions in the universe. Now, award-winning astronomer Emily Levesque shares the stories of modern-day stargazers, the people willing to adventure across high mountaintops and to some of the most remote corners of the planet, all in the name of science.From the lonely quiet of midnight stargazing to tall tales of wild bears loose in the observatory, The Last Stargazers is a love letter to astronomy and an affirmation of the crucial role that humans can and must play in the future of scientific discovery.In this sweeping work of narrative science, Levesque shows how astronomers in this scrappy and evolving field are going beyond the machines to infuse creativity and passion into the stars and inspires us all to peer skyward in pursuit of the universe's secrets.

    Creativity, Inc. is a book for managers who want to lead their employees to new heights, a manual for anyone who strives for originality, and the first-ever, all-access trip into the nerve center of Pixar Animation—into the meetings, postmortems, and “Braintrust” sessions where some of the most successful films in history are made. It is, at heart, a book about how to build a creative culture—but it is also, as Pixar co-founder and president Ed Catmull writes, “an expression of the ideas that I believe make the best in us possible.” For nearly twenty years, Pixar has dominated the world of animation, producing such beloved films as the Toy Story trilogy, Monsters, Inc., Finding Nemo, The Incredibles, Up, and WALL-E, which have gone on to set box-office records and garner thirty Academy Awards. The joyousness of the storytelling, the inventive plots, the emotional authenticity: In some ways, Pixar movies are an object lesson in what creativity really is. Here, in this book, Catmull reveals the ideals and techniques that have made Pixar so widely admired—and so profitable.   As a young man, Ed Catmull had a dream: to make the first computer-animated movie. He nurtured that dream as a Ph.D. student at the University of Utah, where many computer science pioneers got their start, and then forged a partnership with George Lucas that led, indirectly, to his founding Pixar with Steve Jobs and John Lasseter in 1986. Nine years later, Toy Story was released, changing animation forever. The essential ingredient in that movie’s success—and in the thirteen movies that followed—was the unique environment that Catmull and his colleagues built at Pixar, based on philosophies that protect the creative process and defy convention, such as:   • Give a good idea to a mediocre team, and they will screw it up. But give a mediocre idea to a great team, and they will either fix it or come up with something better. • If you don’t strive to uncover what is unseen and understand its nature, you will be ill prepared to lead. • It’s not the manager’s job to prevent risks. It’s the manager’s job to make it safe for others to take them. • The cost of preventing errors is often far greater than the cost of fixing them. • A company’s communication structure should not mirror its organizational structure. Everybody should be able to talk to anybody. • Do not assume that general agreement will lead to change—it takes substantial energy to move a group, even when all are on board.