Somewhere in nature, a killer virus is boiling up in the bloodstream of a bird, bat, monkey, or pig, preparing to jump to a human being. This not-yet-detected germ has the potential to wipe out millions of lives over a matter of weeks or months. That risk makes the threat posed by ISIS, a ground war, a massive climate event, or even the dropping of a nuclear bomb on a major city pale in comparison.In The End of Epidemics, Duke Global Health Institute faculty member and past Chair of the Global Health Council Dr. Jonathan D. Quick examines the eradication of smallpox and devastating effects of influenza, AIDS, SARS, Ebola, and other viral diseases . Analyzing local and global efforts to contain these diseases and citing firsthand accounts of failure and success, Dr. Quick proposes a new set of actions which he has coined "The Power of Seven," to end epidemics before they can begin. These actions include:- Spend prudently to prevent disease before an epidemic strikes, rather than spending too little, too late- Ensure prompt, open, and accurate communication between nations and aid agencies, instead of secrecy and territorial disputes- Fight disease and prevent panic with innovation and good sciencePractical and urgent, The End of Epidemics is crucial reading for citizens, health professionals, and policy makers alike.

    A number of studies show a link between vitamin K2, bone health and heart health. Is vitamin K2 a nutrient you need more of in your diet? As physicians, we feel everyone needs to be aware of the role this vitamin plays in health and wellness. This concise ebook explores the link between vitamin K2 and how it may protect against some of the most common diseases you’re at risk for as you age. Here are some of the questions this book will answer: The Role of Vitamin K in Your Body How Vitamin K2 Differs from Vitamin K1 and Why Most People Don’t Get Enough of It The Various Isoforms of Vitamin K2 and Which Ones Are Most Important for Health The Role Vitamin K2 Plays in Bone Health and Osteoporosis Prevention Vitamin K2 and Heart Disease: Can It Lower Your Risk or Even Reverse Atherosclerosis? Do You Need a Vitamin K2 Supplement? Vitamin K2 and Cancer: Is There a Link? The Role Vitamin K2 Plays in Dental Health Are You at Risk for Vitamin K Deficiency? Can You Get Enough Vitamin K2 Through Diet Alone? The Best Dietary Source of Vitamin K2 Why You Must Have Vitamin K2 if You Take a Vitamin D Supplement Are There Risks to Taking a Vitamin K2 Supplement? One Type of Vitamin K2 Supplement Source You Should Avoid You should have a better understanding of the health benefits of vitamin K2 once you finish.

    Eyes wide open. I was standing at an open window, staring at the dizzying curve of Riverside Drive, five floors below. I’d stopped, somehow, poised, about to jump.Growing up the good girl in an Irish American family full of drinkers and terrible sleepers, Kathleen Frazier was twelve when her seemingly innocent sleepwalking turned dangerous. Over the next few years, she was a popular A+ student by day, the star of her high school musical. At night, she both longed for and dreaded sleep.Frazier moved to Manhattan in the 1980s, hoping for a life in the theater but getting a run of sleepwalking performances instead. Efforts to abate her malady with drinking failed miserably. She became promiscuous, looking for nighttime companionship. Could a bed partner save her from flinging herself down a flight of stairs or out an open window? Exhaustion stalked her, and rest and love were seemingly out of reach.This is the journey Frazier illuminates in her intimate memoir. While highlighting her quest to beat her sleep terrors and insomnia, this is ultimately a story of health, hope, and redemption.

    Before all the NHL's old barns were torn down to make way for bigger, glitzier rinks. Before expansion and parity across the league, just about anything could happen on the ice. And it often did. It was an era when huge personalities dominated the sport; and willpower was often enough to win games. And in the spring of 1993, some of the biggest talents and biggest personalities were on a collision course. The Cinderella Maple Leafs had somehow beaten the mighty Red Wings and then, just as improbably, the St. Louis Blues. Wayne Gretzky's Kings had just torn through the Flames and the Canucks. When they faced each other in the conference final, the result would be a series that fans still talk about passionately 25 years later. Taking us back to that feverish spring, The Last Good Year gives an intimate account not just of an era-defining seven games, but of what the series meant to the men who were changed by it: Marty McSorley, the tough guy who took his whole team on his shoulders; Doug Gilmour, the emerging superstar; celebrity owner Bruce McNall; Bill Berg, who went from unknown to famous when the Leafs claimed him on waivers; Kelly Hrudey, the Kings' goalie who would go on to become a Hockey Night in Canada broadcaster; Kerry Fraser, who would become the game's most infamous referee; and two very different captains, Toronto's bull in a china shop, Wendel Clark, and the immortal Wayne Gretzky. Fast-paced, authoritative, and galvanized by the same love of the game that made the series so unforgettable, The Last Good Year is a glorious testament to a moment hockey fans will never forget.

    There is nothing remotely inevitable about Brexit – except that it will be deeply damaging if it happens. Extricating Britain from Europe will be the greatest challenge this country has faced since the Second World War. And as negotiations with the EU expose the promises of the Brexit campaign to have been hollow, even some Brexit-voters now wish to exercise their democratic right to change their mind, seeing that the most pragmatic option is to … stop. It would certainly be the best thing for Britain. But how can it be done? Haven’t the people spoken?No. In this indispensable handbook, Nick Clegg categorically debunks the various myths that have been used to force Brexit on Britain, not by ‘the people’ but by a small, extremely rich, self-serving elite, and explains precisely how this historic mistake can be reversed – and what you can do to make sure that it is.

    Chronicle of a Plague, Revisited features ten pieces never previously republished outside Christopher Street, as well as a new introduction keenly describing and evaluating a historical moment that still informs and defines today’s world-particularly its community of homosexuals, which, arguably, is still recovering from the devastation of AIDS.

    As gripping as CSI and as eye-opening as Mary Roach’s Stiff, Carney’s The Red Market sheds a blazing new light on the disturbing, billion-dollar business of trading in human body parts, bodies, and child trafficking, raising issues and exposing corruptions almost too bizarre and shocking to imagine.

    We heeded almost none of them. The result is a pandemic on a scale never before seen in our lifetimes. In this captivating, authoritative, and eye-opening book, science journalist Debora MacKenzie lays out the full story of how and why it happened: the previous viruses that should have prepared us, the shocking public health failures that paved the way, the failure to contain the outbreak, and most importantly, what we must do to prevent future pandemics.Debora MacKenzie has been reporting on emerging diseases for more than three decades, and she draws on that experience to explain how COVID-19 went from a potentially manageable outbreak to a global pandemic. Offering a compelling history of the most significant recent outbreaks, including SARS, MERS, H1N1, Zika, and Ebola, she gives a crash course in Epidemiology 101--how viruses spread and how pandemics end--and outlines the lessons we failed to learn from each past crisis. In vivid detail, she takes us through the arrival and spread of COVID-19, making clear the steps that governments knew they could have taken to prevent or at least prepare for this. Looking forward, MacKenzie makes a bold, optimistic argument: this pandemic might finally galvanize the world to take viruses seriously. Fighting this pandemic and preventing the next one will take political action of all kinds, globally, from governments, the scientific community, and individuals--but it is possible.No one has yet brought together our knowledge of COVID-19 in a comprehensive, informative, and accessible way. But that story can already be told, and Debora MacKenzie's urgent telling is required reading for these times and beyond. It is too early to say where the COVID-19 pandemic will go, but it is past time to talk about what went wrong and how we can do better.

    As of 2004 an estimated 40 million people were living with the disease, and about 20 million had died. Despite rapid scientific advances there is still no cure and the drugs are expensive and toxic. In the developing world, especially in parts of Africa, life expectancy has plummeted to below 35 years, causing a serious decline in economic growth, a sharp increase in orphans, and the imminent collapse of health care systems. The news is not all bleak though. There have been unprecedented breakthroughs in understanding diseases and developing drugs. Because the disease is so closely linked to sexual activity and drug use, the need to understand and change behavior has caused us to reassess what it means to be human and how we should operate in the globalizing world. This Very Short Introduction tackles the science, the international and local politics, the fascinating demographics, and the devastating consequences of the disease, and suggests how we must respond.About the Series: Oxford's Very Short Introductions offers concise and original introductions to a wide range of subjects--from Islam to Sociology, Politics to Classics, and Literary Theory to History. Not simply a textbook of definitions, each volume provides trenchant and provocative--yet always balanced and complete--discussions of the central issues in a given topic. Every Very Short Introduction gives a readable evolution of the subject in question, demonstrating how it has developed and influenced society. Whatever the area of study, whatever the topic that fascinates the reader, the series has a handy and affordable guide that will likely prove indispensable.

    Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis.In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns.The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe.Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.

    His full accounting does honor to the medical professionals around the country who've risked their lives to fight the virus, revealing America in all its vulnerability, courage, and potential.

    Staff nursing in a ward where she's challenged by an inventory driven ward sister, she reckons it's time to swap such trivialities for life as a district nurse.Independent thinking is one thing, but Jane's about to find that the drama on district can demand instant reaction; and without hospital back up, she's usually the one having to provide it. She meets a rich cast of patients all determined to follow their own individual star, and goes to Edinburgh where Queen Victoria's Jubilee Institute's nurse training is considered the cr me de la cr me of the district nursing world.Call Me Sister recalls Jane's challenging and often hilarious route to realizing her own particular dream.

    Yet, in his many travels, he'd never visited the Northwest Territories, "the white ribbon across the top of North American maps found beneath a paper crease still crisp at the fold." After an all-too-brief visit to a literary festival in Yellowknife, Bidini was hooked on the place and its people. From the time he returned home, all he could do was think about going back to the North.At the same time, Bidini found himself at a career crossroads. His position as a columnist with a national newspaper had come to an end, leaving him reflecting on his lifelong love of newspapers and questioning the future of journalism in Canada. Writing had always been Bidini's way to make sense of the world around him and he was determined to find an outlet for his unique perspective. Still fresh with the memories of his recent visit to the Northwest Territories, Bidini contacts the Yellowknifer, one of the last truly local and independent newspapers, and signs on as a guest columnist for an unforgettable summer. Midnight Light: A Personal Journey to the North, is Dave Bidini's fast, funny and, at times, powerfully poignant chronicle of the incredible time he spent "up there" in the NWT. The Yellowknifer, like the city it serves, bucks all of the trends and invokes all of the charms and frustrations of stubborn nationalism. The newspaper is completely locally-focused and treats the global news sharescape as if it never existed. The paper gives Bidini a ground-level view of a city and its environs, including Great Bear Lake, Tuktoyaktuk, and Nahanni National Park, that are on one hand lost in time, and on another faced with the very stark realities of poverty, racism, addiction, and hopelessness. Along the way, Midnight Light introduces readers to an extraordinary cast of characters, including Dene elders and entrepreneurs adapting to a changing way of life, various artists who are giving the region a powerful voice to the rest of the world, politicians and law enforcement officers who are dealing with the community's difficult history and economic realities, and an assortment of complicated souls from the South who have travelled North as a "last chance" to build lives for themselves. Woven throughout Midnight Light's tremendous narrative is the story of the irascible John McFadden, a veteran Toronto newspaper crime reporter who "escaped" to Yellowknife. McFadden is the key character in the Yellowknifer's ongoing fight with the authorities (RCMP forces) who do not take kindly to journalistic doggedness. McFadden and the paper became the centre of attention across the country when he was charged with obstruction and threatened with jail time. He was found not guilty and the police were forced to change their tactics. Yet the tension between the RCMP and the Yellowknifer remains unresolved. In Midnight Light, Dave Bidini brings Yellowknife, the Northwest Territories and its remarkable and proud people to brilliant life.

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.

    From a fortress-like former bank building, American Pain's doctors distributed massive quantities of oxycodone to hundreds of customers a day, mostly traffickers and addicts who came by the vanload. Inked muscle-heads ran the clinic's security. Former strippers operated the pharmacy, counting out pills and stashing cash in garbage bags. Under their lab coats, the doctors carried guns and it was all legal sort of. American Pain was the brainchild of Chris George, a 27-year-old convicted drug felon. The son of a South Florida home builder, Chris George grew up in ultra-rich Wellington, where Bill Gates, Springsteen, and Madonna kept houses. Thick-necked from weightlifting, he and his twin brother hung out with mobsters, invested in strip clubs, brawled with cops, and grinned for their mug shots. After the housing market stalled, a local doctor clued in the brothers to the burgeoning underground market for lightly regulated prescription painkillers. In Florida, pain clinics could dispense the meds, and no one tracked the patients. Seizing the opportunity, Chris George teamed up with the doctor, and word got out. Just two years later Chris had raked in $40 million, and 90 percent of the pills his doctors prescribed flowed north to feed the rest of the country's insatiable narcotics addiction. Meanwhile, hundreds more pain clinics in the mold of American Pain had popped up in the Sunshine State, creating a gigantic new drug industry. American Pain chronicles the rise and fall of this game-changing pill mill, and how it helped tip the nation into its current opioid crisis, the deadliest drug epidemic in American history. The narrative swings back and forth between Florida and Kentucky, and is populated by a gaudy and diverse cast of characters. This includes the incongruous band of wealthy bad boys, thugs and esteemed physicians who built American Pain, as well as penniless Kentucky clans who transformed themselves into painkiller trafficking rings. It includes addicts whose lives were devastated by American Pain's drugs, and the federal agents and grieving mothers who labored for years to bring the clinic's crew to justice."