The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    A hiker brutally murdered, then thrown off a cliff in a remote mountain range. A devious killer who hid his wife's body under a thick cement patio. For investigators, the story is often the same: they know a murder took place, they may even know who did it. But without key evidence, pursuing a conviction is nearly impossible. That's when they call NecroSearch International. Necrosearch boasts a brain trust of the nation's top scientists, specialists, and behaviourists who use the latest technology and techniques to help solve "unsolvable" crimes, no matter how decayed the corpse, no matter how cleverly the killer has hidden the victim's body. Now, for the first time ever, readers are taken on a fascinating, often-shocking journey into a realm of crime investigation of which few people are aware. Necrosearch's most challenging cases are described, step-by-step, as these modern-day Sherlock Holmes's detect bodies and evidence thought irretrievable, and testify in court to bring cold-blooded killers to justice.

    Steve’s nightmare goes from bad to worse when he learns that the mysterious death was no accident but the act of a sociopath.  A sociopath he knows and who has information that could destroy Steve’s career and marriage.  A sociopath for whom killing is more than a means to an end: it’s a game.  Because he is under a cloud of suspicion and has no evidence, he knows that any accusations he makes won’t be believed. So he must struggle to turn the tables, even as the killer skillfully blocks his every move. Detailing the politics of hospitals, the hierarchy among doctors and the life and death decisions that are made by flawed human beings, Doing Harm marks the debut of a major fiction career.

    But here is the secret world of the index: an unsung but extraordinary everyday tool, with an illustrious but little-known history.Charting its curious path from the monasteries and universities of thirteenth-century Europe to Silicon Valley in the twenty-first, Dennis Duncan reveals how the index has saved heretics from the stake, kept politicians from high office, and made us all into the readers we are today. We follow it through German print shops and Enlightenment coffee houses, novelists’ living rooms and university laboratories, encountering emperors and popes, philosophers and prime ministers, poets, librarians, and—of course—indexers along the way. Duncan reveals the vast role of the index in our evolving literary and intellectual culture, and he shows that in the Age of Search we are all index-rakers at heart.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    Now, in The Organ Thieves, Pulitzer Prize-nominated journalist Chip Jones exposes the horrifying inequality surrounding Tucker's death and how he was used as a human guinea pig without his family's permission or knowledge. The circumstances surrounding his death reflect the long legacy of mistreating African Americans that began more than a century before with cadaver harvesting and worse. It culminated in efforts to win the heart transplant race in the late 1960s.

    And yet, very few of its readers know that the subject of the novel was inspired by a real-life case: the 1948 abduction of eleven-year-old Sally Horner.Weaving together suspenseful crime narrative, cultural and social history, and literary investigation, The Real Lolita tells Sally Horner’s full story for the very first time. Drawing upon extensive investigations, legal documents, public records, and interviews with remaining relatives, Sarah Weinman uncovers how much Nabokov knew of the Sally Horner case and the efforts he took to disguise that knowledge during the process of writing and publishing Lolita.Sally Horner’s story echoes the stories of countless girls and women who never had the chance to speak for themselves. By diving deeper in the publication history of Lolita and restoring Sally to her rightful place in the lore of the novel’s creation, The Real Lolita casts a new light on the dark inspiration for a modern classic.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    . . The book works on two levels, much like a good Holmes case."--TimeFor all the scores of biographies of Arthur Conan Doyle, creator of the most famous detective in the world, there is no recent book that tells this remarkable story--in which Conan Doyle becomes a real-life detective on an actual murder case. In Conan Doyle for the Defense, Margalit Fox takes us step by step inside Conan Doyle's investigative process and illuminates a murder mystery that is also a morality play for our time--a story of ethnic, religious, and anti-immigrant bias.In 1908, a wealthy woman was brutally murdered in her Glasgow home. The police found a convenient suspect in Oscar Slater--an immigrant Jewish cardsharp--who, despite his obvious innocence, was tried, convicted, and consigned to life at hard labor in a brutal Scottish prison. Conan Doyle, already world famous as the creator of Sherlock Holmes, was outraged by this injustice and became obsessed with the case. Using the methods of his most famous character, he scoured trial transcripts, newspaper accounts, and eyewitness statements, meticulously noting myriad holes, inconsistencies, and outright fabrications by police and prosecutors. Finally, in 1927, his work won Slater's freedom.Margalit Fox, a celebrated longtime writer for The New York Times, has "a nose for interesting facts, the ability to construct a taut narrative arc, and a Dickens-level gift for concisely conveying personality" (Kathryn Schulz, New York). In Conan Doyle for the Defense, she immerses readers in the science of Edwardian crime detection and illuminates a watershed moment in the history of forensics, when reflexive prejudice began to be replaced by reason and the scientific method.Praise for Conan Doyle for the Defense"Splendid . . . The ingredients are too good to pass up: a famous detective novelist actually playing detective, a man serving time for a murder he did not commit, and a criminal justice system slowly, and reluctantly, reckoning with the advent of forensic science." -- Sarah Weinman, The New Republic "Entertaining."--Newsday

    Married to her college sweetheart, she owns a chain of upscale hair salons, and Derek runs his own company. They're admired in their community and are a loving family—until their world falls apart the day their son Sebastian is taken.A year later, Marin is a shadow of herself. The FBI search has gone cold. The publicity has faded. She and her husband rarely speak. She hires a P.I. to pick up where the police left off, but instead of finding Sebastian, she learns that Derek is having an affair with a younger woman. This discovery sparks Marin back to life. She's lost her son; she's not about to lose her husband, too. Kenzie is an enemy with a face, which means this is a problem Marin can fix.Permanently.All it takes to unravel a life is one little secret...Overwhelmed by tragedy, a woman desperately tries to save her marriage in award-winning author Jennifer Hillier's Little Secrets, a riveting novel of psychological suspense.

    They never saw her again. Her abduction was one of the most notorious episodes of the vicious conflict known as The Troubles. Everyone in the neighborhood knew the I.R.A. was responsible. But in a climate of fear and paranoia, no one would speak of it. In 2003, five years after an accord brought an uneasy peace to Northern Ireland, a set of human bones was discovered on a beach. McConville's children knew it was their mother when they were told a blue safety pin was attached to the dress--with so many kids, she had always kept it handy for diapers or ripped clothes.Patrick Radden Keefe's mesmerizing book on the bitter conflict in Northern Ireland and its aftermath uses the McConville case as a starting point for the tale of a society wracked by a violent guerrilla war, a war whose consequences have never been reckoned with. The brutal violence seared not only people like the McConville children, but also I.R.A. members embittered by a peace that fell far short of the goal of a united Ireland, and left them wondering whether the killings they committed were not justified acts of war, but simple murders.Patrick Radden Keefe writes an intricate narrative about a notorious killing in Northern Ireland and its devastating repercussions.

    This fascinating collection of historical curiosities explores some of the strangest cases that have perplexed doctors across the world.From seventeenth-century Holland to Tsarist Russia, from rural Canada to a whaler in the Pacific, many are monuments to human stupidity – such as the sailor who swallowed dozens of penknives to amuse his shipmates, or the chemistry student who in 1850 arrived at a hospital in New York with his penis trapped inside a bottle, having unwisely decided to relieve himself into a vessel containing highly reactive potassium. Others demonstrate exceptional surgical ingenuity long before the advent of anaesthesia – such as a daring nineteenth-century operation to remove a metal fragment from beneath a conscious patient’s heart. We also hear of the weird, often hilarious remedies employed by physicians of yore – from crow’s vomit to port-wine enemas – the hazards of such everyday objects as cucumbers and false teeth, and miraculous recovery from apparently terminal injuries.

    Guy Leschziner's patients, there is no rest for the weary in mind and body. Insomnia, narcolepsy, night terrors, sleep apnea, and sleepwalking are just a sampling of conditions afflicting sufferers who cannot sleep--and their experiences in trying are the stuff of nightmares. Demoniac hallucinations frighten people into paralysis. Restless legs rock both the sleepless and their sleeping partners with unpredictable and uncontrollable kicking. Out-of-sync circadian rhythms confuse the natural body clock's days and nights.Then there are the extreme cases. A woman in a state of deep sleep who gets dressed, unlocks her car, and drives for several miles before returning to bed. The man who has spent decades cleaning out kitchens while "sleep-eating." The teenager prone to the serious, yet unfortunately nicknamed "Sleeping Beauty Syndrome" stuck in a cycle of excessive unconsciousness, binge eating, and uncharacteristic displays of aggression and hyper-sexuality while awake.With compassionate stories of his patients and their conditions, Dr. Leschziner illustrates the neuroscience behind our sleeping minds, revealing the many biological and psychological factors necessary in getting the rest that will not only maintain our physical and mental health, but improve our cognitive abilities and overall happiness.

    Brinkley–America’s most brazen young con man–arrived in the tiny town of Milford, Kansas. He set up a medical practice and introduced an outlandish surgical method using goat glands to restore the fading virility of local farmers.It was all nonsense, of course, but thousands of paying customers quickly turned “Dr.” Brinkley into America’s richest and most famous surgeon. His notoriety captured the attention of the great quackbuster Morris Fishbein, who vowed to put the country’s “most daring and dangerous” charlatan out of business.Their cat-and-mouse game lasted throughout the 1920s and ’30s, but despite Fishbein’s efforts Brinkley prospered wildly. When he ran for governor of Kansas, he invented campaigning techniques still used in modern politics. Thumbing his nose at American regulators, he built the world’s most powerful radio transmitter just across the Rio Grande to offer sundry cures, and killed or maimed patients by the score, yet his warped genius produced innovations in broadcasting that endure to this day. By introducing country music and blues to the nation, Brinkley also became a seminal force in rock ’n’ roll. In short, he is the most creative criminal this country has ever produced.Culminating in a decisive courtroom confrontation that pit Brinkley against his nemesis Fishbein, Charlatan is a marvelous portrait of a boundlessly audacious rogue on the loose in an America that was ripe for the bamboozling.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.