Yet, David Wootton argues, from the fifth century BC until the 1930s, doctors actually did more harm than good. In this controversial new account of the history of medicine, he asks just how much good it has done us over the years, and how much harm it continues to do today.

    What drives the drug trade, and how has it come to be what it is today? A global history of the acquisition of progressively more potent means of altering ordinary waking consciousness, this book is the first to provide the big picture of the discovery, interchange, and exploitation of the planet's psychoactive resources, from tea and kola to opiates and amphetamines.

    But the war produced the largest biological crisis of the nineteenth century, and as historian Jim Downs reveals in this groundbreaking volume, it had deadly consequences for hundreds of thousands of freed people.In Sick from Freedom, Downs recovers the untold story of one of the bitterest ironies in American history--that the emancipation of the slaves, seen as one of the great turning points in U.S. history, had devastating consequences for innumerable freed people. Drawing on massive new research into the records of the Medical Division of the Freedmen's Bureau-a nascent national health system that cared for more than one million freed slaves-he shows how the collapse of the plantation economy released a plague of lethal diseases. With emancipation, African Americans seized the chance to move, migrating as never before. But in their journey to freedom, they also encountered yellow fever, smallpox, cholera, dysentery, malnutrition, and exposure. To address this crisis, the Medical Division hired more than 120 physicians, establishing some forty underfinanced and understaffed hospitals scattered throughout the South, largely in response to medical emergencies. Downs shows that the goal of the Medical Division was to promote a healthy workforce, an aim which often excluded a wide range of freedpeople, including women, the elderly, the physically disabled, and children. Downs concludes by tracing how the Reconstruction policy was then implemented in the American West, where it was disastrously applied to Native Americans.The widespread medical calamity sparked by emancipation is an overlooked episode of the Civil War and its aftermath, poignantly revealed in Sick from Freedom.

    Before the invention of photography, artists played an essential role in medical science, recording human anatomy in startlingly direct and often moving images. Over 400 years, beginning with Vesalius, they charted the main systems of the body, made precise studies of living organs, documented embryonic development, and described pathologies. Human Anatomy includes portfolios of the work of 19 great anatomical artists, with concise biographies, and culminates with the Visible Human Project, which uses digital tools to visualize the human body.Praise for Human Anatomy:"From Leonardo da Vinci's exquisite pen-and-ink drawings of the human skeleton to the digital Visible Human Project in its three-dimensional glory, this fascinating book . . . documents more than 500 years of anatomical illustration in living color." -Scientific American

    Why should he or anyone else care what became of his corpse? In The Work of the Dead, acclaimed cultural historian Thomas Laqueur examines why humanity has universally rejected Diogenes’s argument. No culture has been indifferent to mortal remains. Even in our supposedly disenchanted scientific age, the dead body still matters—for individuals, communities, and nations. A remarkably ambitious history, The Work of the Dead offers a compelling and richly detailed account of how and why the living have cared for the dead, from antiquity to the twentieth century.The book draws on a vast range of sources—from mortuary archaeology, medical tracts, letters, songs, poems, and novels to painting and landscapes in order to recover the work that the dead do for the living: making human communities that connect the past and the future. Laqueur shows how the churchyard became the dominant resting place of the dead during the Middle Ages and why the cemetery largely supplanted it during the modern period. He traces how and why since the nineteenth century we have come to gather the names of the dead on great lists and memorials and why being buried without a name has become so disturbing. And finally, he tells how modern cremation, begun as a fantasy of stripping death of its history, ultimately failed—and how even the ashes of the victims of the Holocaust have been preserved in culture.A fascinating chronicle of how we shape the dead and are in turn shaped by them, this is a landmark work of cultural history.

    in the landmark 1927 case Buck v. Bell. The ruling allowed states to forcibly sterilize residents in order to prevent "feebleminded and socially inadequate" people from having children. It is the only time the Supreme Court endorsed surgery as a tool of government policy. Paul Lombardo’s startling narrative exposes the Buck case’s fraudulent roots.In 1924 Carrie Buck—involuntarily institutionalized by the State of Virginia after she was raped and impregnated—challenged the state’s plan to sterilize her. Having already judged her mother and daughter mentally deficient, Virginia wanted to make Buck the first person sterilized under a new law designed to prevent hereditarily "defective" people from reproducing. Lombardo’s more than twenty-five years of research and his own interview with Buck before she died demonstrate conclusively that she was destined to lose the case before it had even begun. Neither Carrie Buck nor her mother and daughter were the "imbeciles" condemned in the Holmes opinion. Her lawyer—a founder of the institution where she was held—never challenged Virginia’s arguments and called no witnesses on Buck’s behalf. And judges who heard her case, from state courts up to the U.S. Supreme Court, sympathized with the eugenics movement. Virginia had Carrie Buck sterilized shortly after the 1927 decision.Though Buck set the stage for more than sixty thousand involuntary sterilizations in the United States and was cited at the Nuremberg trials in defense of Nazi sterilization experiments, it has never been overturned. Three Generations, No Imbeciles tracks the notorious case through its history, revealing that it remains a potent symbol of government control of reproduction and a troubling precedent for the human genome era.

    From such twenty-first-century forces, we have seen declines in previous global health gains, with sharp increases in vaccine-preventable and neglected diseases on the Arabian Peninsula, in Venezuela, in parts of Africa, and even on the Gulf Coast of the United States. In Preventing the Next Pandemic, international vaccine scientist and tropical disease and coronavirus expert Peter J. Hotez, MD, PhD, argues that we can--and must--rely on vaccine diplomacy to address this new world order in disease and global health. Detailing his years in the lab developing new vaccines, Hotez also recounts his travels around the world to shape vaccine partnerships with people in countries both rich and poor in an attempt to head off major health problems. Building on the legacy of Dr. Albert Sabin, who developed the oral polio vaccine with Soviet scientists at the height of the Cold War, he explains how he is still working to refresh and redirect vaccine diplomacy toward neglected and newly emerging diseases.Hotez reveals how--during his Obama-era tenure as the US Science Envoy for the Middle East and North Africa, which coincided with both the rise in these geopolitical forces and climate change--he witnessed tropical infectious diseases and established vaccine partnerships that may still combat them up close. He explores why, since 2015, we've seen the decline of global cooperation and cohesion, to the detriment of those programs that are meant to benefit the most vulnerable people in the world. Unfortunately, Hotez asserts, these negative global events kick off a never-ending loop. Problems in a country may lead to disease outbreaks, but those outbreaks can lead to further problems--such as the impact of coronavirus on China's society and economy, which has been felt around the globe. Zeroing in on the sociopolitical and environmental factors that drive our most controversial and pressing global health concerns, Hotez proposes historically proven methods to soothe fraught international relations while preparing us for a safer, healthier future. He hammers home the importance of public engagement to communicate the urgency of embracing science during troubled times.Touching on a range of disease, from leishmaniasis, schistosomiasis, and Middle East Respiratory Syndrome (MERS) to COVID-19, Preventing the Next Pandemic has always been a timely goal, but it will be even more important in a COVID and post-COVID world.

    Yet why, over three hundred years after it began, is the Enlightenment so profoundly misunderstood as controversial, the expression of soulless calculation? The answer may be that, to an extraordinary extent, we have accepted the account of the Enlightenment given by its conservative enemies. Ritchie Robertson goes back into the “long eighteenth century,” from approximately 1680 to 1790, to reveal what this much-debated period was really about.Any account of the Enlightenment must be in large part a history of ideas. But Robertson argues that it is not solely a philosophical movement; the Enlightenment saw the publication of the Encyclopédie, which is not only a historical and philosophical compendium, but also an illustrated guide to all sorts of contemporary machinery, handicrafts, and trades aimed to improve people’s lives in immediate and practical ways. Robertson chronicles the campaigns mounted by some Enlightened figures against specific evils such as capital punishment, judicial torture, serfdom and witchcraft trials, featuring the experiences of major figures like Voltaire and Diderot with ordinary people who lived through this extraordinary moment. Robertson gives due attention to philosophical and theological debates, but also looks to literature, music, and the visual arts as prominent means of conveying enlightenment ideas.In seeking to correct one-sided views of the Enlightenment, Robertson ultimately puts forward his own. He does not reduce this transformative period to a formula, but instead makes the claim that indeed the Enlightenment was an attempt to increase human happiness, and to claim that happiness was possible in this world, without needing any compensatory belief in a better one beyond the grave.

    Markel writes of the physical and emotional damage caused by the then-heralded wonder drug, and how each man ultimately changed the world in spite of it—or because of it. One became the father of psychoanalysis; the other, of modern surgery. Both men were practicing medicine at the same time in the 1880s: Freud at the Vienna General Hospital, Halsted at New York’s Bellevue Hospital. Markel writes that Freud began to experiment with cocaine as a way of studying its therapeutic uses—as an antidote for the overprescribed morphine, which had made addicts of so many, and as a treatment for depression.  Halsted, an acclaimed surgeon even then, was curious about cocaine’s effectiveness as an anesthetic and injected the drug into his arm to prove his theory. Neither Freud nor Halsted, nor their colleagues, had any idea of the drug’s potential to dominate and endanger their lives. Addiction as a bona fide medical diagnosis didn’t even exist in the elite medical circles they inhabited.  In An Anatomy of Addiction, Markel writes about the life and work of each man, showing how each came to know about cocaine; how Freud found that the drug cured his indigestion, dulled his aches, and relieved his depression. The author writes that Freud, after a few months of taking the magical drug, published a treatise on it, Über Coca, in which he described his “most gorgeous excitement.” The paper marked a major shift in Freud’s work: he turned from studying the anatomy of the brain to exploring the human psyche.  Halsted, one of the most revered of American surgeons, became the head of surgery at the newly built Johns Hopkins Hospital and then professor of surgery, the hospital’s most exalted position, committing himself repeatedly to Butler Hospital, an insane asylum, to withdraw from his out-of control cocaine use.  Halsted invented modern surgery as we know it today: devising new ways to safely invade the body in search of cures and pioneering modern surgical techniques that controlled bleeding and promoted healing. He insisted on thorough hand washing, on scrub-downs and whites for doctors and nurses, on sterility in the operating room—even inventing the surgical glove, which he designed and had the Goodyear Rubber Company make for him—accomplishing all of this as he struggled to conquer his unyielding desire for cocaine.  An Anatomy of Addiction tells the tragic and heroic story of each man, accidentally struck down in his prime by an insidious malady: tragic because of the time, relationships, and health cocaine forced each to squander; heroic in the intense battle each man waged to overcome his affliction as he conquered his own world with his visionary healing gifts. Here is the full story, long overlooked, told in its rich historical context.

    From Jamestown to the Marlboro Man, the plant occupied the heart of the nation’s economy and expressed its enduring myths. But today smoking rates have declined and smokers are exiled from many public spaces. The story of tobacco’s fortunes may seem straightforward: science triumphed over our addictive habits and the cynical machinations of tobacco executives. Yet the reality is more complicated. Both the cigarette’s popularity and its eventual decline reflect a parallel course of shifting political priorities. The tobacco industry flourished with the help of the state, but it was the concerted efforts of citizen nonsmokers who organized to fight for their right to clean air that led to its undoing.After the Great Depression, public officials and organized tobacco farmers worked together to ensure that the government’s regulatory muscle was more often deployed to promote tobacco than to protect the public from its harms. Even as evidence of the cigarette’s connection to cancer grew, medical experts could not convince officials to change their stance. What turned the tide, Sarah Milov argues, was a new kind of politics: a movement for nonsmokers’ rights. Activists and public-interest lawyers took to the courts, the streets, city councils, and boardrooms to argue for smoke-free workplaces and allied with scientists to lobby elected officials.The Cigarette restores politics to its rightful place in the tale of tobacco’s rise and fall, illustrating America’s continuing battles over corporate influence, individual responsibility, collective choice, and the scope of governmental power.

    While fueling extraordinary advances in all fields of human endeavor, this vision perpetuated a hidden yet persistent agenda: the delusion that human nature and society could be fitted into precise and manageable rational categories. Stephen Toulmin confronts that agenda—its illusions and its consequences for our present and future world."By showing how different the last three centuries would have been if Montaigne, rather than Descartes, had been taken as a starting point, Toulmin helps destroy the illusion that the Cartesian quest for certainty is intrinsic to the nature of science or philosophy."—Richard M. Rorty, University of Virginia"[Toulmin] has now tackled perhaps his most ambitious theme of all. . . . His aim is nothing less than to lay before us an account of both the origins and the prospects of our distinctively modern world. By charting the evolution of modernity, he hopes to show us what intellectual posture we ought to adopt as we confront the coming millennium."—Quentin Skinner, New York Review of Books

    The Industrial Revolution brought not simply misery and poverty. On the contrary, Griffin shows how it raised incomes, improved literacy, and offered exciting opportunities for political action. For many, this was a period of new, and much valued, sexual and cultural freedom. This rich personal account focuses on the social impact of the Industrial Revolution, rather than its economic and political histories. In the tradition of best-selling books by Liza Picard, Judith Flanders, and Jerry White, Griffin gets under the skin of the period and creates a cast of colorful characters, including factory workers, miners, shoemakers, carpenters, servants, and farm laborers.

    Neck-deep in work that can be messy and confounding and naive in the ways of public communication, scientists are often unable to package their insights into the neat narratives that the public requires. Enter celebrities, advocates, lobbyists, and the funders behind them, who take advantage of scientists' reluctance to provide easy answers, flooding the media with misleading or incorrect claims about health risks. Amid this onslaught of spurious information, Americans are more confused than ever about what's good for them and what isn't. In Bad Advice, Paul A. Offit shares hard-earned wisdom on the dos and don'ts of battling misinformation. For the past twenty years, Offit has been on the front lines in the fight for sound science and public heath. Stepping into the media spotlight as few scientists have done--such as being one of the first to speak out against conspiracy theories linking vaccines to autism--he found himself in the crosshairs of powerful groups intent on promoting pseudoscience. Bad Advice discusses science and its adversaries: not just the manias stoked by slick charlatans and their miracle cures but also corrosive, dangerous ideologies such as Holocaust and climate-change denial.

    Warnings that depressive disorder is a leading cause of worldwide disability have been accompanied by a massive upsurge in the consumption of antidepressant medication, widespread screening for depression in clinics and schools, and a push to diagnose depression early, on the basis of just a few symptoms, in order to prevent more severe conditions from developing.In The Loss of Sadness, Allan V. Horwitz and Jerome C. Wakefield argue that, while depressive disorder certainly exists and can be a devastating condition warranting medical attention, the apparent epidemic in fact reflects the way the psychiatric profession has understood and reclassified normal human sadness as largely an abnormal experience. With the 1980 publication of the landmark third edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III), mental health professionals began diagnosing depression based on symptoms—such as depressed mood, loss of appetite, and fatigue—that lasted for at least two weeks. This system is fundamentally flawed, the authors maintain, because it fails to take into account the context in which the symptoms occur. They stress the importance of distinguishing between abnormal reactions due to internal dysfunction and normal sadness brought on by external circumstances. Under the current DSM classification system, however, this distinction is impossible to make, so the expected emotional distress caused by upsetting events—for example, the loss of a job or the end of a relationship—could lead to a mistaken diagnosis of depressive disorder. Indeed, it is this very mistake that lies at the root of the presumed epidemic of major depression in our midst.

    Loury has become one of our most prominent black intellectuals—and, because of his challenges to the orthodoxies of both left and right, one of the most controversial. A major statement of a position developed over the past decade, this book both epitomizes and explains Loury’s understanding of the depressed conditions of so much of black society today—and the origins, consequences, and implications for the future of these conditions.Using an economist’s approach, Loury describes a vicious cycle of tainted social information that has resulted in a self-replicating pattern of racial stereotypes that rationalize and sustain discrimination. His analysis shows how the restrictions placed on black development by stereotypical and stigmatizing racial thinking deny a whole segment of the population the possibility of self-actualization that American society reveres—something that many contend would be undermined by remedies such as affirmative action. On the contrary, this book persuasively argues that the promise of fairness and individual freedom and dignity will remain unfulfilled without some forms of intervention based on race.Brilliant in its account of how racial classifications are created and perpetuated, and how they resonate through the social, psychological, spiritual, and economic life of the nation, this compelling and passionate book gives us a new way of seeing—and, perhaps, seeing beyond—the damning categorization of race in America.