The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free.Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers.Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

    Hurley chronicles today’s diabetes epidemic—how the disease has grown so dramatically, why the American Diabetes Association focuses its attention on just a small handful of available treatments, and why the research being done today doesn’t look beyond accepted types of treatments. Just as Eric Schlosser’s Fast Food Nation uncovered the sordid details leading to an epidemic of obesity, Dan Hurley uncovers the hidden truths of what is being researched—and even more importantly, what is not. Diabetes Rising explores both Type 1 and Type 2 diabetes, one of the leading causes of deaths in the United States. With ground-breaking research and compelling stories seen through an investigative, historical, and narrative lens, Diabetes Rising couples big-picture insight with intimate reporting. The book yields riveting insight into the struggle between the pervasive malady and the medical community’s ongoing search for answers. Informed but not dominated by the author’s own experience as a Type 1 diabetic, Diabetes Rising grants exclusive access to new studies, innovative treatments, and determined patients. Hurley’s sharp, entertaining, and provocative read will change how readers understand diabetes, and the cultures, conditions, and medical climates in which it thrives.

    Critics everywhere have hailed this book as a classic in the making.

    “I smoked in my twenties. I preferred red wine to sparkling water. I ate too much milk chocolate. I liked limericks. I know all the wrong I’ve done. But also, more than any of that, I’ve always longed for children.” Yet there she was: successful, social, mostly happy, and not a mother. Knowing that her chances of becoming pregnant naturally were quickly fading, Finn decided to gamble: she—like some 85,000 other women in the U.S. each year—would attempt in vitro fertilization. Almost three years later, she’s still trying, and in the process has become an accidental pioneer (and, at times, a guinea pig) in the ever-evolving science of IVF.“The Baby Chase” is a primer for anyone contemplating or undergoing IVF. More than that, it’s a story of longing, hope—and hormones—that will appeal to all parents, present and future.Finn’s engaging and honest account sheds light on a subject that few people who undergo IFV are willing to talk about: what happens when the science doesn’t work. “Usually, it’s only the people who come out on the other side, beaming, with a baby on one hip, who speak up about IVF,” she writes. “We never hear from those IVF has failed - it’s too crushing to talk about. We don’t hear from men and women in the middle of treatment, either.... People like me.”

    Shell traces the epidemic's inception in the Ice Age, its rise during the Industrial Revolution, and its growth through the early days of medicine and into modernity. She takes readers to the front lines of the struggle to come to grips with this baffling plague — from a children's food marketing convention, to the cutthroat race to find the obese gene, to a far-flung tropical island, where a horrifying outbreak of obesity has helped unravel the disorder's genetic and evolutionary roots. Offering an unflinching insider's look into the radical and controversial surgical and pharmacological approaches used to combat what drug makers have dubbed the trillion-dollar disease, Shell takes aim at the collusion of industry and government that lies behind the crises and shows conclusively that obesity is not a matter of gluttony or weak will, but of an increasingly greedy culture preying on vulnerable human biology. Gripping and provocative, The Hungry Gene is the unsettling saga of how the world got fat — and what we can do about it.

    What seemed like a harmless cold morphed into a global pandemic that would wipe out as many as a hundred-million people - ten times as many as the Great War. German troops faltered lending the allies the winning advantage, India turned its sights to independence while South Africa turned to God. In Western Samoa a quarter of the population died; in some parts of Alaska, whole villages were wiped out. Civil unrest sparked by influenza shaped nations and heralded a new era of public health where people were no longer blamed for contracting disease. Using real case histories, we take a journey through the world in 1918, and look at the impact of Spanish flu on populations from America, to France, to the Arctic, and the scientific legacy this deadly virus has left behind.

    She taught her family how to read Scott’s medical chart and to ask pointed questions, no longer leaving his care to the medical professionals who had overdosed him with drugs to the very brink of death in less than three days.“Jo, you have to tell people what they’ve done to me. You have to tell them!”pleaded her little brother, as he lay writhing in agony.In “For the Love of Scott!”, the author recollects her family’s poignant story of love, bewilderment, and lingering frustration when faced with catastrophic medical mistakes. Read the experiences of Scott Hamilton’s family members as they struggle through a storm of horrific medical errors that could have been prevented and recognize what you need to do when someone you love is faced with life-threatening circumstances created by health experts.It took Jo 27 years to put this heartbreaking event down on paper. Writing opened old wounds and required hours of research and documentation. It forced her family to relive a chapter in their own lives that they desperately wanted closed. Yet, they rallied together to help Jo with her mission to keep that promise.To help further her goals, Jo Hamilton will be donating a portion of the proceeds from the sale of her book, to the 1984 Olympic Gold Medal Winner, Scott Hamilton's foundation, The Scott Hamilton CARES Initiative. The Scott Hamilton CARES Initiative was created to help with cancer research, support cancer patients and their families, and find a cure cancer.

    This book extracts the essence of this Indian philosophy and provides a wealth of timeless rituals to effect positive change.Prajna offers rituals and routines for the entire day, from the moment you wake up and need the energy and positive mindset to help you start the morning, to night-time practices that allow you to wind down, relax and get the most benefit from the healing power of sleep. In between there are numerous breathing exercises, mindfulness techniques, yoga stretches and simple recipes to enjoy, all to help you destress and reset, bringing you back to yourself and to lasting peace and happiness.

    Jill McKeever, author, wrote this family-pleasing cookbook solely for Instant Pot® owners. Inside you'll find 34 plant-based, oil-free meals and sides your family will ask for again and again. Looking at the Instant Pot® with all its function buttons can give some folks the feeling that cooking is made easier with a push of a button. As for others, multiple buttons can be overwhelming and confusing. Take a breath. There are four cooking functions most commonly used in this book; Keep Warm/Cancel, Sauté, Manual, and Slow Cook. The cooking directions are written so even the newest Instant Pot® owner can whip up a delicious meal with ease. Jill compiled all her fan’s favorite Instant Pot® recipes from her YouTube channel, Simple Daily Recipes, and brought them together in this book. Every recipe comes with a mouthwatering photo and easy to read list of ingredients and directions. Also included is a quick reference pressure cooking chart for beans/legumes, grains, and vegetables. 

You won’t have to worry about your family eating their veggies when you make, Awesome Tex-Mex Lasagna Stack, Barbecue Cabbage Sandwiches, Barbecue Shredded Soy Curls, Barbecue Lentils, Bring Along Black Bean Hash, Chili Bean Goulash, Creamy Soy Curls Alfredo, Extra Creamy Tomato Spinach Pasta, Ethiopian Inspired Stew, Memaw’s Beefless Stew, Memaw’s Soy Curls Pot Pie, Go-To Lentil Soup, Slow Cooked Pasta-free Lasagna, Spinach Tacos, Thick & Creamy Nacho Sauce, Vegan Sausage Scramble, Veggies in Creamy Curry Sauce or Veggies in Creamy Curry Sauce. Order O M Gee Good! Instant Pot® Meals, Plant-Based & Oil-Free and get started making meals your family will want to eat week after week and will even be able to cook for themselves. WOOT WOOT!

    It is more concise and easier to read than some, yet it covers the breadth of emergency medicine practice more comprehensively than others. The bottom line is that I like this book. Just as previous editions did, the seventh presents all of the most pertinent and up-to-date information in a well-organized format that is comprehensive yet easy to read. That and many of the attractive new features in this current edition will ensure its place on my bookshelf for years to come."--JAMAWith 418 contributors representing over 120 medical centers around the world, Tintinalli’s Emergency Medicine is the most practical and clinically rigorous reference of its kind. It covers everything from prehospital care, disaster preparedness, and basic resuscitative techniques, to all the major diseases requiring emergency treatment, such as pulmonary emergencies, renal and GU disorders, and hemophilia. This authoritative, in-depth coverage makes this classic text indispensible not only in emergency departments, but also for residents and practitioners when studying or preparing for any exam they may face.While continuing to provide the most current information for acute conditions, the Seventh Edition of Tintinalli’s Emergency Medicine has been substantially revised and updated to cover all of the conditions for which patients seek emergency department care in a concise and easy-to-read-manner.NEW Features• Full-color design with more figures and tables than ever• Reader-friendly chapter presentation makes it easy to find important material.• Updated tables covering drugs and important clinical information• Patient safety considerations and injury prevention are integrated into chapters, as appropriate• Total revision of the dermatology section enables diagnosis by lesion description and body area affected, and provides current treatment• Organ systems sections reorganized to reflect considerations for actual clinical practice.• New chapters: New adult chapters include Natural Disasters, Aneurysms of the Aorta and Major Arteries; Hip and Knee Pain, Aortic Dissection; Acute Urinary Retention; Subarachnoid Hemorrhage and Intracranial Bleeding; Clotting Disorders; Community –acquired Pneumonia and Noninfectious Pulmonary Infiltrates; Type I Diabetes; Type II Diabetes; Anemia; Tests of Hemostasis; Clotting Disorders; Head Injury in Adults and Children; the Transplant Patient; Grief, Death and Dying; and Legal Issues in Emergency Medicine. Twelve new pediatric chapters including The Diabetic Child, Hematologic-Oncologic Emergencies, Ear and Mastoids, Eye Problems in Infants and Children, Neck Masses, GI Bleeding, Nose and Sinuses, Urologic and Gynecologic Procedures in children, Renal emergencies in children, Behavioral and Psychiatric Disorders in children, Pediatric Procedures, Pediatric ECG Interpretation• Greater coverage of procedures throughout for the most common conditions seen in the emergency department.• Companion DVD features an additional 17 chapters, such as Hyperbaric Oxygen Therapy, Principles of Imaging, Prison Medicine, Military Medicine, The Violent Patient, Forensics, Wound Ballistics, and Drug Interactions.• Companion DVD also features videos and animations for teaching and learning performance of important procedures, especially Ultrasound-Guided Procedures

    Several champions made astonishing, almost mysterious, strength and muscle gains--at least two broke new powerlifting world records—thanks to kettlebell training. Pavel decided to reverse engineer this "What the Hell" effect experienced by the champions—so all others could benefit from their success. Return of the Kettlebell presents the final fruit of Pavel's research—combining the very best of ancient lifting wisdom with modern day scientific breakthroughs. Central to Pavel's new program for explosive muscle gain is the skillful use of double kettlebells. Discover smokers like the Double Clean, classic strength builders like the Double Snatch and Double Press and enjoy the supreme intensity of the Double Clean and Jerk. Like the Breakfast of Champions, consume what's on the Return of the Kettlebell menu and watch yourself grow—and grow! Chapter 1: The Science of Big Heresy, but it works! Maverick superstar Vasily Alexeevev snuck this renegade method past the apparatchiks' noses—and packed serious pounds of beef on his grateful students in record time… Page 2 Why the Russian kettlebell beats all comers as the ideal tool for repetition quick lifts… Page 3 Why "fast eccentrics" are now all the rage among serious hypertrophy experts Understand how to manipulate Z-band streaming for faster muscle growth… Page 4 Shoot from both barrels! How a double whammy of "quick wacks" and "slow squeezes" will leave no muscle untrashed in your quest for explosive growth… Page 5 3 styles of Russian kettlebell training—which one is right for you?… Pages 6–8 Chapter 2: Explode and Grow This "Smokers' Delight" will jack your heart rate through the roof… Page 11 The best starting position for more powerful—and safer—shoulder contractions… Page 13 The ladies' way to trouble-free Double Cleans… Page 17 Yes, this will build monstrous biceps—but you'll be risking a serious injury… Page 19 Bad idea! Why "scooping" can only hurt your future strength development… Page 20 The difference between anatomical and biomechanical breathing—and which to choose for greater strength development… Page 21 The essential prerequisites for a powerful Double Snatch… Page 22 You MUST employ this secret in the Double Snatch—or risk your back and face… Page 24 Could this method be the best ever upper back and shoulder builder?... Page 26 Employ this little-known method for the ultimate in lateral deltoid development… Page 28 How to correctly perform the Viking Push Press—for way more powerful quads and tris… Page30 The 2 biggest problems a beginner faces with the Push Press—and the perfect solution to both. The correct grip for optimal explosiveness in the Snatch… Page 33 The essential prerequisite for maximal force transmission in the arms and legs… Page 34 The correct neck position for a truly effective Push Press—and a great way to save your back… Page 36 The 4 major keys to efficient and painless shock absorption 3 important reasons NEVER to raise your heels when push pressing… Page 40 Why it's best to stay "light" with the Viking Push Press… Page 43 Risk being accused of steroid abuse—when you gain like crazy from this ultimate kettlebell lift… Page 46 How to optimize your Clean and Jerk—for inhuman results 4 superb Russian drills to i

    He chronicles some of the most formative calls of his career in this autobiography that reads like crime fiction. McCarthy demonstrates with detail and clarity that the difficult choice is often the right choice. While not for the faint of heart, each entry in this collection provides poignant insight into the bonds between medics and the people and city they serve.

    The germ revolution came after two decades of scientific virtuosity, outstanding feats of intellectual courage and bitter personal rivalries, doctors at last recognised that infectious diseases are caused by mircoscopic organisms.

    She cuts through the thicket of confusing—and often downright wrong—advice on nutrition and gives you easy-to-digest, bite-sized servings of real scientific information so you can discover which foods your body needs to heal and thrive. Since Joan wears two hats—as a psychologist and a cell biologist—you can trust her to psych out your inner saboteur, enabling you to make the changes you’ve been dreaming of. And as a busy woman who loves good food, she’ll teach you how to make simple, scrumptious, satisfying meals that you and your family will love whether you’re omnivores, vegans, or vegetarians. In this groundbreaking book, Joan will help you:Get up-to-date information on the nutrition revolutionMake friends with the plants that feed your gut bacteriaLose the weight and keep it offUnderstand how diet changes your genes and how your genes determine your best dietFill out a health symptom checklist and track the changes as your personalized PlantPlus Diet optimizes your metabolismKnow which tests to ask your doctor for and whyCreate a sleek and streamlined PlantPlus kitchenMake fabulous meals in minutes with simple recipes and meal plans

    Scott guides readers through the latest advances in stem cell research in clear, accessible language, telling the stories of the researchers who are exploring the potential of stem cells to cure cancer, grow new organs, and repair the immune system. He also leads readers through a discussion of the question at the heart of the explosive ethical debate: How, as a society, do we balance our responsibilities to the unborn and the sick? Stem Cell Now is essential reading for anyone who wants to build an informed opinion on stem cell research.