This new edition, written with five new authors, has been brought fully up to date, and incorporates insights very recently derived from genome sequencing in a variety of organisms. The book is an authoritative and comprehensive survey of the fundamentals of molecular biology, from basic mechanisms to the elaborate role of gene regulation in embryonic development and evolution. Although updated, the twentyone chapters of the new edition retain the distinctive and celebrated features of the original work, including introductory chapters on the history of genetics and molecular biology and an emphasis throughout on the chemical underpinnings of molecular biology. The new team of authors brings to this edition awardwinning teaching experience and outstanding research achievements. By revealing the intellectual framework and experimental approaches that made new discoveries in the field possible, the new edition highlights the significance of the molecular approach for all of biology.

    The term “complexity” can be misleading, however, because what makes West’s discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses. Fascinated by issues of aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science, creating a new understanding of energy use and metabolism: West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal’s circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient—and lives 25% longer. This speaks to everything from how long we can expect to live to how many hours of sleep we need. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism's body. West's work has been game-changing for biologists, but then he made the even bolder move of exploring his work's applicability to cities. Cities, too, are constellations of networks and laws of scalability relate with eerie precision to them. For every doubling in a city's size, the city needs 15% less road, electrical wire, and gas stations to support the same population. More amazingly, for every doubling in size, cities produce 15% more patents and more wealth, as well as 15% more crime and disease. This broad pattern lays the groundwork for a new science of cities. Recently, West has applied his revolutionary work on cities and biological life to the business world. This investigation has led to powerful insights into why some companies thrive while others fail. The implications of these discoveries are far-reaching, and are just beginning to be explored. Scale is a thrilling scientific adventure story about the elemental natural laws that bind us together in simple but profound ways. Through the brilliant mind of Geoffrey West, we can envision how cities, companies and biological life alike are dancing to the same simple, powerful tune, however diverse and unrelated they are to each other.From the Hardcover edition.

    This thorough revision provides a survey by groups, emphasizing adaptive morphology and physiology, while covering anatomical ground plans and basic developmental patterns. New co-author Richard Fox brings to the revision his expertise as an ecologist, offering a good balance to Ruppert's background as a functional morphologist. Rich illustrations and extensive citations make the book extremely valuable as a teaching tool and reference source.

    Readers are provided once again with an instructive mix of mathematics, physics, statistics, and information theory.All the essential topics in information theory are covered in detail, including entropy, data compression, channel capacity, rate distortion, network information theory, and hypothesis testing. The authors provide readers with a solid understanding of the underlying theory and applications. Problem sets and a telegraphic summary at the end of each chapter further assist readers. The historical notes that follow each chapter recap the main points.The Second Edition features: * Chapters reorganized to improve teaching * 200 new problems * New material on source coding, portfolio theory, and feedback capacity * Updated referencesNow current and enhanced, the Second Edition of Elements of Information Theory remains the ideal textbook for upper-level undergraduate and graduate courses in electrical engineering, statistics, and telecommunications.

    From Edward Lorenz’s discovery of the Butterfly Effect, to Mitchell Feigenbaum’s calculation of a universal constant, to Benoit Mandelbrot’s concept of fractals, which created a new geometry of nature, Gleick’s engaging narrative focuses on the key figures whose genius converged to chart an innovative direction for science. In Chaos, Gleick makes the story of chaos theory not only fascinating but also accessible to beginners, and opens our eyes to a surprising new view of the universe.

    With the addition of new chapters, thorough updating, and a new co-author, this latest edition represents the definitive introduction to behavioral genetics: the crossroads where the fields of psychology, psychiatry, and genetics intersect.

    From the very first attempts by the Greeks to grapple with the complexities of our known world to the latest application of infinity in physics, The Road to Reality carefully explores the movement of the smallest atomic particles and reaches into the vastness of intergalactic space. Here, Penrose examines the mathematical foundations of the physical universe, exposing the underlying beauty of physics and giving us one the most important works in modern science writing.

    The R language is recognised as one of the most powerful and flexible statistical software packages, and it enables the user to apply many statistical techniques that would be impossible without such software to help implement such large data sets.

    This clear, concise look at the basic principles and concepts of genetics uses a human genetics perspective to discuss the methods and experiments upon which genetic principles are based, such as DNA replication.

    Learn You a Haskell for Great Good! introduces programmers familiar with imperative languages (such as C++, Java, or Python) to the unique aspects of functional programming. Packed with jokes, pop culture references, and the author's own hilarious artwork, Learn You a Haskell for Great Good! eases the learning curve of this complex language, and is a perfect starting point for any programmer looking to expand his or her horizons. The well-known web tutorial on which this book is based is widely regarded as the best way for beginners to learn Haskell, and receives over 30,000 unique visitors monthly.

    Here is the Naked Ape at his most primal in love, at work, at war. Meet man as he really is: relative to the apes, stripped of his veneer as we see him courting, making love, sleeping, socializing, grooming, playing. The Naked Ape takes its place alongside Darwin’s Origin of the Species, presenting man not as a fallen angel, but as a risen ape, remarkable in his resilience, energy and imagination, yet an animal nonetheless, in danger of forgetting his origins. With its penetrating insights on man's beginnings, sex life, habits and our astonishing bonds to the animal kingdom, The Naked Ape is a landmark, at once provocative, compelling and timeless.

    An evolutionary perspective forms the foundation of the entire discussion. The book begins with the natural history of the planet, considers portions of the whole in the middle chapters, and ends with another perspective of the entire planet in the concluding chapter. Its unique organization of focusing only on several key concepts in each chapter sets it apart from the competition. .

    The study of type systems--and of programming languages from a type-theoretic perspective--has important applications in software engineering, language design, high-performance compilers, and security.This text provides a comprehensive introduction both to type systems in computer science and to the basic theory of programming languages. The approach is pragmatic and operational; each new concept is motivated by programming examples and the more theoretical sections are driven by the needs of implementations. Each chapter is accompanied by numerous exercises and solutions, as well as a running implementation, available via the Web. Dependencies between chapters are explicitly identified, allowing readers to choose a variety of paths through the material.The core topics include the untyped lambda-calculus, simple type systems, type reconstruction, universal and existential polymorphism, subtyping, bounded quantification, recursive types, kinds, and type operators. Extended case studies develop a variety of approaches to modeling the features of object-oriented languages.

    The new edition includes the most up-to-date research developments and many more examples and problems.

    Gödel received public recognition of his work in 1951 when he was awarded the first Albert Einstein Award for achievement in the natural sciences--perhaps the highest award of its kind in the United States. The award committee described his work in mathematical logic as "one of the greatest contributions to the sciences in recent times."However, few mathematicians of the time were equipped to understand the young scholar's complex proof. Ernest Nagel and James Newman provide a readable and accessible explanation to both scholars and non-specialists of the main ideas and broad implications of Gödel's discovery. It offers every educated person with a taste for logic and philosophy the chance to understand a previously difficult and inaccessible subject.New York University Press is proud to publish this special edition of one of its bestselling books. With a new introduction by Douglas R. Hofstadter, this book will appeal students, scholars, and professionals in the fields of mathematics, computer science, logic and philosophy, and science.