He and his climbing partner, Simon, reached the summit of the remote Siula Grande in June 1985. A few days later, Simon staggered into Base Camp, exhausted and frost-bitten, with news that that Joe was dead.What happened to Joe, and how the pair dealt with the psychological traumas that resulted when Simon was forced into the appalling decision to cut the rope, makes not only an epic of survival but a compelling testament of friendship.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Aspirin, the world's most widely used drug, is based on compounds originally extracted from the bark of a willow tree, and more than a quarter of medicines found on pharmacy shelves contain plant compounds. Now Western medicine, faced with health crises such as AIDS, Alzheimer's disease, and cancer, has begun to look to the healing plants used by indigenous peoples to develop powerful new medicines. Nowhere is the search more promising than in the Amazon, the world's largest tropical forest, home to a quarter of all botanical species on this planet—as well as hundreds of Indian tribes whose medicinal plants have never been studied by Western scientists. In Tales of a Shaman's Apprentice, ethnobotanist Mark J. Plotkin recounts his travels and studies with some of the most powerful Amazonian shamans, who taught him the plant lore their tribes have spent thousands of years gleaning from the rain forest.For more than a decade, Dr. Plotkin has raced against time to harvest and record new plants before the rain forests' fragile ecosystems succumb to overdevelopment—and before the Indians abandon their own culture and learning for the seductive appeal of Western material culture. Tales of a Shaman's Apprentice relates nine of the author's quests, taking the reader along on a wild odyssey as he participates in healing rituals; discovers the secret of curare, the lethal arrow poison that kills in minutes; tries the hallucinogenic snuff epena that enables the Indians to speak with their spirit world; and earns the respect and fellowship of the mysterious shamans as he proves that he shares both their endurance and their reverence for the rain forest. Mark Plotkin combines the Darwinian spirit of the great writer-explorers of the nineteenth century—curious, discursive, and rigorously scientific—with a very modern concern for the erosion of our environment and the vanishing culture of native peoples.

    He learned the tricks of master trail-builders, hunted down long-lost Cherokee trails, and traced the origins of our road networks and the Internet. In each chapter, Moor interweaves his adventures with findings from science, history, philosophy, and nature writing—combining the nomadic joys of Peter Matthiessen with the eclectic wisdom of Lewis Hyde’s The Gift.Throughout, Moor reveals how this single topic—the oft-overlooked trail—sheds new light on a wealth of age-old questions: How does order emerge out of chaos? How did animals first crawl forth from the seas and spread across continents? How has humanity’s relationship with nature and technology shaped world around us? And, ultimately, how does each of us pick a path through life?Moor has the essayist’s gift for making new connections, the adventurer’s love for paths untaken, and the philosopher’s knack for asking big questions. With a breathtaking arc that spans from the dawn of animal life to the digital era, On Trails is a book that makes us see our world, our history, our species, and our ways of life anew.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    Z99 grit and courage members of the French Alpine Club face frostbite snow blindness and near death to reach the summit of the uncharted 26493-foot Himalayan peak Annapurna

    In The Woman with a Worm in Her Head, Dr. Pamela Nagami reveals-through real-life cases-the sobering facts about some of the world's most horrific diseases: the warning signs, the consequences, treatments, and most compellingly, what it feels like to make medical and ethical decisions that can mean the difference between life and death.Unfailingly precise, calmly instructive, and absolutely engrossing, The Woman with the Worm in Her Head offers both useful information and enjoyable reading.

    She chaperoned baby sea turtles on their journey to sea. She pursued bad guys on her galloping patrol horse. She jumped into rescue helicopters bound for the heart of the Grand Canyon. She won arguments with bears. She slept with a few too many rattlesnakes. Hell yeah, it was the best job in the world! Fortunately, Andrea survived it. In this graphic and yet surprisingly funny account of her and others’ extraordinary careers, Lankford unveils a world in which park rangers struggle to maintain their idealism in the face of death, disillusionment, and the loss of a comrade killed while holding that thin green line between protecting the park from the people, the people from the park, and the people from each other. Ranger Confidential is the story behind the scenery of the nation’s crown jewels—Yosemite, Grand Canyon, Yellowstone, Great Smokies, Denali. In these iconic landscapes, where nature and humanity constantly collide, scenery can be as cruel as it is redemptive.

    In 1903, while on a three-day camping trip with President Theodore Roosevelt, he convinced the president of the importance of a national conservation program, and he is widely recognized for saving the Grand Canyon and Arizona's Petrified Forest. Muir's writing, based on journals he kept throughout his life, gives our generation a picture of an America still wild and unsettled only one hundred years ago. In The Wildernesss World of John Muir Edwin Way Teale has selected the best of Muir's writing from all of his major works—including My First Summer in the Sierra and Travels in Alaska—to provide a singular collection that provides to be "magnificent, thrilling, exciting, breathtaking, and awe-inspiring" (Kirkus Reviews).

    Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria.Through a fresh and engaging examination of our evolutionary history, Dr. Moalem reveals how many of the conditions that are diseases today actually gave our ancestors a leg up in the survival sweepstakes. When the option is a long life with a disease or a short one without it, evolution opts for disease almost every time.Everything from the climate our ancestors lived in to the crops they planted and ate to their beverage of choice can be seen in our genetic inheritance. But Survival of the Sickest doesn't stop there. It goes on to demonstrate just how little modern medicine really understands about human health, and offers a new way of thinking that can help all of us live longer, healthier lives..

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    It started out as a simple hike in the Utah canyonlands on a warm Saturday afternoon. For Aron Ralston, a twenty-seven-year-old mountaineer and outdoorsman, a walk into the remote Blue John Canyon was a chance to get a break from a winter of solo climbing Colorado's highest and toughest peaks. He'd earned this weekend vacation, and though he met two charming women along the way, by early afternoon he finally found himself in his element: alone, with just the beauty of the natural world all around him. It was 2:41 P.M. Eight miles from his truck, in a deep and narrow slot canyon, Aron was climbing down off a wedged boulder when the rock suddenly, and terrifyingly, came loose. Before he could get out of the way, the falling stone pinned his right hand and wrist against the canyon wall. And so began six days of hell for Aron Ralston. With scant water and little food, no jacket for the painfully cold nights, and the terrible knowledge that he'd told no one where he was headed, he found himself facing a lingering death -- trapped by an 800-pound boulder 100 feet down in the bottom of a canyon. As he eliminated his escape options one by one through the days, Aron faced the full horror of his predicament: By the time any possible search and rescue effort would begin, he'd most probably have died of dehydration, if a flash flood didn't drown him before that. What does one do in the face of almost certain death? Using the video camera from his pack, Aron began recording his grateful good-byes to his family and friends all over the country, thinking back over a life filled with adventure, and documenting a last will and testament with the hope that someone would find it. (For their part, his family and friends had instigated a major search for Aron, the amazing details of which are also documented here for the first time.) The knowledge of their love kept Aron Ralston alive, until a divine inspiration on Thursday morning solved the riddle of the boulder. Aron then committed the most extreme act imaginable to save himself. Between a Rock and a Hard Place -- a brilliantly written, funny, honest, inspiring, and downright astonishing report from the line where death meets life -- will surely take its place in the annals of classic adventure stories.

    Gnawing at reason and enslaving minds, it has killed many and defeated countless others. But in 1953, Edmund Hillary and Tenzing Norgay stared into its dark eye and did not waver. On May 29, they pushed spent bodies and aching lungs past the achievable to pursue the impossible. At a terminal altitude of 29,028 feet, they stood triumphant atop the highest peak in the world. With nimble words and a straightforward style, New Zealand mountaineering legend Hillary recollects the bravery and frustration, the agony and glory that marked his Everest odyssey. From the 1951 expedition that led to the discovery of the Southern Route, through the grueling Himalayan training of 1952, and on to the successful 1953 expedition led by Colonel John Hunt, Hillary conveys in precise language the mountain's unforgiving conditions. In explicit detail he recalls an Everest where chaotic icefalls force costly detours, unstable snow ledges promise to avalanche at the slightest misstep, and brutal weather shifts from pulse-stopping cold to fiendish heat in mere minutes. In defiance of these torturous conditions, Hillary remains enthusiastic and never hesitates in his quest for the summit. Despite the enormity of his and Norgay's achievement, he regards himself, Norgay, and the other members of his expedition as hardworking men, not heroes. And while he never would have reached the top without practiced skill and technical competence, his thrilling memoir speaks first to his admiration of the human drive to explore, to understand, to risk, and to conquer.

    For a generation of American climbers, The White Spider has been a formative book--yet it has long been out-of-print in America. This edition awaits discovery by Harrer's new legion of readers.

    Worried that she was losing her passion for the scientific research she once loved, she was compelled to experience wildness again, to be guided by the sounds of birds and to follow the trails of animals.In March of 2012, she and her husband set off on a 4,000-mile wilderness journey from the Pacific rainforest to the Alaskan Arctic, traveling by rowboat, ski, foot, raft, and canoe. Together, they survived harrowing dangers while also experiencing incredible moments of joy and grace -- migrating birds silhouetted against the moon, the steamy breath of caribou, and the bond that comes from sharing such experiences.A unique blend of science, adventure, and personal narrative, The Sun is a Compass explores the bounds of the physical body and the tenuousness of life in the company of the creatures who make their homes in the wildest places left in North America. Inspiring and beautifully written, this love letter to nature is a lyrical testament to the resilience of the human spirit.Winner of the 2019 Banff Mountain Book Competition: Adventure Travel