Prior to December 2018, no individual had ever crossed the landmass of Antarctica alone, without support and completely human powered. Yet, Colin O’Brady was determined to do just that, even if, ten years earlier, there was doubt that he’d ever walk again normally. From the depths of a tragic accident, he fought his way back. In a quest to unlock his potential and discover what was possible, he went on to set three mountaineering world records before turning to this historic Antarctic challenge. O’Brady’s pursuit of a goal that had eluded many others was made even more intense by a head-to-head battle that emerged with British polar explorer Captain Louis Rudd—also striving to be “the first.” Enduring Antarctica’s sub-zero temperatures and pulling a sled that initially weighed 375 pounds—in complete isolation and through a succession of whiteouts, storms, and a series of near disasters—O’Brady persevered. Alone with his thoughts for nearly two months in the vastness of the frozen continent—gripped by fear and doubt—he reflected on his past, seeking courage and inspiration in the relationships and experiences that had shaped his life.

    In a fascinating blend of adventure and science, Stark recreates in heart-stopping detail what happens to our bodies and minds in the last moments of life when an extreme adventure goes awry.

    In college, I ran against Kenyans, and wondered whether endurance genes might have traveled with them from East Africa. At the same time, I began to notice that a training group on my team could consist of five men who run next to one another, stride for stride, day after day, and nonetheless turn out five entirely different runners. How could this be?We all knew a star athlete in high school. The one who made it look so easy. He was the starting quarterback and shortstop; she was the all-state point guard and high-jumper. Naturals. Or were they?The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports? Or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training?The truth is far messier than a simple dichotomy between nature and nurture. In the decade since the sequencing of the human genome, researchers have slowly begun to uncover how the relationship between biological endowments and a competitor’s training environment affects athleticism. Sports scientists have gradually entered the era of modern genetic research.In this controversial and engaging exploration of athletic success, Sports Illustrated senior writer David Epstein tackles the great nature vs. nurture debate and traces how far science has come in solving this great riddle. He investigates the so-called 10,000-hour rule to uncover whether rigorous and consistent practice from a young age is the only route to athletic excellence.Along the way, Epstein dispels many of our perceptions about why top athletes excel. He shows why some skills that we assume are innate, like the bullet-fast reactions of a baseball or cricket batter, are not, and why other characteristics that we assume are entirely voluntary, like an athlete’s will to train, might in fact have important genetic components.This subject necessarily involves digging deep into sensitive topics like race and gender. Epstein explores controversial questions such as:Are black athletes genetically predetermined to dominate both sprinting and distance running, and are their abilities influenced by Africa’s geography?Are there genetic reasons to separate male and female athletes in competition?Should we test the genes of young children to determine if they are destined for stardom?Can genetic testing determine who is at risk of injury, brain damage, or even death on the field?Through on-the-ground reporting from below the equator and above the Arctic Circle, revealing conversations with leading scientists and Olympic champions, and interviews with athletes who have rare genetic mutations or physical traits, Epstein forces us to rethink the very nature of athleticism.

    When Dr. Van Tilburg's beeper goes off, the call may take him racing up a mountain peak to rescue an injured hiker, into a blizzard to search for missing skiers, or to a mountain airplane crash scene for body recovery. Dr. Van Tilburg's work requires a unique combination of emergency medicine, survival skills, agility, and extreme sports. In Mountain Rescue Doctor, Van Tilburg shares personal stories of harrowing and suspenseful rescues and recoveries, including the recent Mount Hood disaster, which claimed the lives of three climbers. Mountain Rescue Doctor is an exhilarating tour through the perils of nature and medicine.

      We swim in freezing Arctic waters and piranha-infested rivers to test our limits. We swim for pleasure, for exercise, for healing. But humans, unlike other animals that are drawn to water, are not natural-born swimmers. We must be taught. Our evolutionary ancestors learned for survival; now, in the twenty-first century, swimming is one of the most popular activities in the world.Why We Swim is propelled by stories of Olympic champions, a Baghdad swim club that meets in Saddam Hussein’s palace pool, modern-day Japanese samurai swimmers, and even an Icelandic fisherman who improbably survives a wintry six-hour swim after a shipwreck. New York Times contributor Bonnie Tsui, a swimmer herself, dives into the deep, from the San Francisco Bay to the South China Sea, investigating what about water—despite its dangers—seduces us and why we come back to it again and again.

    I didn’t run for times, to win, to impress: I ran for me. When I ran my bum cheeks rubbed together, so much so that if I was going on a long run I’d have to ‘lube up’. I maintained that I was not a ‘real’ runner – I just liked to run so that I could eat cake." Anna was never anything like those ‘real’ runners on telly – all spindly limbs, tiny shorts and split times – but when she read about New Zealand’s 3,000-kilometre-long Te Araroa Trail, she began to wonder… perhaps being a ‘real’ runner was overrated. Maybe she could just run it anyway? Travelling alone through New Zealand’s backcountry for 148 days, she scrambled through forests, along ridge-lines, over mountain passes, along beaches and across swollen rivers. Running up to 52 kilometres in a day, she slept wild most nights, and was taken into the homes and hearts of the kiwi people in between. The Pants of Perspective is a witty, colourful and at times painfully raw account of a journey to the edge of what a woman believes herself to be capable of. It is a coming-of-age story which will lead you on a roller coaster ride through fear, vulnerability, courage and failure. For anyone who has ever dreamt of taking on a great challenge, but felt too afraid to begin – this story is for you.

    But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime.Miraculously, Fajgenbaum survived--only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends, and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself.More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide.

    Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future.

    Rana Awdish never imagined that an emergency trip to the hospital would result in hemorrhaging nearly all of her blood volume and losing her unborn first child. But after her first visit, Dr. Awdish spent months fighting for her life, enduring consecutive major surgeries and experiencing multiple overlapping organ failures. At each step of the recovery process, Awdish was faced with something even more unexpected: repeated cavalier behavior from her fellow physicians—indifference following human loss, disregard for anguish and suffering, and an exacting emotional distance.Hauntingly perceptive and beautifully written, In Shock allows the reader to transform alongside Awidsh and watch what she discovers in our carefully-cultivated, yet often misguided, standard of care. Awdish comes to understand the fatal flaws in her profession and in her own past actions as a physician while achieving, through unflinching presence, a crystalline vision of a new and better possibility for us all.As Dr. Awdish finds herself up against the same self-protective partitions she was trained to construct as a medical student and physician, she artfully illuminates the dysfunction of disconnection. Shatteringly personal, and yet wholly universal, she offers a brave road map for anyone navigating illness while presenting physicians with a new paradigm and rationale for embracing the emotional bond between doctor and patient.

     It is a remarkable portrait, too, of the life of a psychiatric asylum--the sort of community in which, for better and for worse, hundreds of thousands of people lived out their lives.More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

    Written while Abbey was working as a ranger at Arches National Park outside of Moab, Utah, Desert Solitaire is a rare view of one man’s quest to experience nature in its purest form.Through prose that is by turns passionate and poetic, Abbey reflects on the condition of our remaining wilderness and the future of a civilization that cannot reconcile itself to living in the natural world as well as his own internal struggle with morality. As the world continues its rapid development, Abbey’s cry to maintain the natural beauty of the West remains just as relevant today as when this book was written.

    Only a few species of wild animals can survive its harsh climate. In this modern classic, Barry Lopez explores the many-faceted wonders of the Far North: its strangely stunted forest, its mesmerizing aurora borealis, its frozen seas. Musk oxen, polar bears, narwhal, and other exotic beasts of the region come alive through Lopez’s passionate and nuanced observations. And, as he examines the history and culture of the indigenous people, along with parallel narratives of intrepid, often underprepared and subsequently doomed polar explorers, Lopez drives to the heart of why the austere and formidable Arctic is also a constant source of breathtaking beauty, beguilement, and wonder.Written in prose as memorably pure as the land it describes, Arctic Dreams is a timeless mediation on the ability of the landscape to shape our dreams and to haunt our imaginations.

    It’s so bound up with our deepest feelings that emotional trauma causes it to change shape.Practising cardiologist Sandeep Jauhar beautifully weaves his own experiences with the defining discoveries of the past to tell the story of our most vital organ. He looks at some of the pioneers who risked their careers and their patients’ lives to better understand the heart. People like Daniel Hale Williams, who performed the world’s first documented heart surgery, and Wilson Greatbatch, who accidentally invented the pacemaker.Amid gripping scenes from the operating theatre, Jauhar interweaves stories about the patients he’s treated with the moving tale of his family’s own history of heart problems, from his grandfather’s sudden death in India – an event that sparked his life-long obsession – to the ominous signs of how he himself might die.He also confronts the limits of medical technology and argues that future progress will be determined more by how we choose to live rather than by any device we invent.

    By examining fossils and DNA, Shubin shows us that our hands actually resemble fish fins, our head is organized like that of a long-extinct jawless fish, and major parts of our genome look and function like those of worms and bacteria.Shubin makes us see ourselves and our world in a completely new light. Your Inner Fish is science writing at its finest-enlightening, accessible, and told with irresistible enthusiasm.

    This is a true account of his hike from Georgia to Maine, bringing to the reader the life of the towns and the people he meets along the way.