Its job is to protect us from cancer. This gene--known simply as p53--constantly scans our cells to ensure that when they grow and divide as part of the routine maintenance of our bodies, they do so without mishap. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, sending in the repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or handicapped by some other fault in the system. Not surprisingly, p53 is the most studied single gene in history. p53: The Gene that Cracked the Cancer Code tells the story of the discovery of the gene and of medical science's mission to unravel its mysteries and get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, the book reveals the excitement of the hunt for new cures--the hype, the enthusiasm, the lost opportunities, the blind alleys and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is at the cutting edge. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

    Your brain can't function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together.Sekeres, who writes regularly for the Well section of the New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family's wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimacy of the conversations Sekeres has with his patients, and watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it--describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia.The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

     A distraught woman who regrets not going to see a GP sooner. More Googled self-diagnoses than one can count… After three years as one of London’s doctors - as full-time night-time GP doing the house calls that no-one else wants to do - Alex Rudd has switched to working in surgeries. Rudd travels to a different place surgery each day, helping those struggling to cope with patient numbers and seeing those that might not otherwise be seen. With limited time to spend on each patient, he must walk the difficult line between caring for patients while diagnosing and prescribing efficiently. Hilarious diagnoses mix with genuine tragedies as Rudd sees a variety of patients, with all sorts of medical conditions. In this follow-up to “London Call-Out: Confessions of a Doctor in the Capital”, Rudd presents us with another window into the world of the freelance GP today, and the challenges they face. With moments that stir admiration and sadness, this timely and insightful memoir is as thought-provoking as it is entertaining.

    

    . . brilliantly integrat[es] science, literature, and pop culture into elegant and insightful commentaries on the most interesting and important questions of our time. A delightful read.”—Michael Shermer, author of The Science of Good and Evil“Entertaining and thought-provoking.”—Steven Pinker, author of The Blank SlateIf we are, in part, a product of our genes, can free will exist? Incisive and engaging, this indispensable tour of evolutionary biology runs the gamut of contemporary debates, from science and religion to our place in the universe.David Barash is the author of The Myth of Monogamy and Madame Bovary’s Ovaries. He lives in Redmond, Washington.

    It uses a taxonomic approach for the study of pathogens.

    Well, I was diagnosed 24 years ago, and I still learned something new on every page.”—Michael Kinsley, Vanity Fair columnist and author of Old Age: A Beginner’s Guide Here is the book that John Vine and his wife, Joanne, wish they could have consulted when John was first diagnosed with Parkinson’s disease—a nontechnical, personal guide written from the patient’s perspective. Relying on his experiences over the past 12 years, John writes knowledgeably about all aspects of the disease. John also interviewed other Parkinson’s patients and their partners, whose stories and advice he includes throughout the book. “I wish we’d had John Vine’s book when my brother-in-law was diagnosed. The book is highly informative, unflinchingly honest, and reassuringly optimistic. It’s just what the doctor should have ordered.”—Cokie Roberts, best-selling author and political commentator on ABC News and NPR “John Vine details, in a compelling and accessible way, his experience with Parkinson’s disease. His book is an extraordinary guide to living successfully with Parkinson’s, and a must read for all who want to better understand the condition. Although diagnosed with Parkinson’s, my father lived an active and productive life until his death at age 94. As the book makes clear, while each patient’s journey is unique, common approaches are indispensable in treating the symptoms of the disease.”—Eric H. Holder, Jr. served as the 82nd Attorney General of the United States from 2009 to 2015 “John Vine has written the best primer I’ve ever read for newly diagnosed Parkinson’s patients and their families. It helps them cope with the shock of diagnosis, gives them (jargon-free) the scientific basics they need to know, describes the symptoms they may experience (making clear that every case is different) and catalogs the resources available to navigate living with Parkinson’s. John humanizes the book by describing his own experience and that of 22 other patients and their partners. I’d urge every neurologist to have copies of Vine’s primer on hand to help new PD on their journey forward.”—Morton Kondracke, author of Saving Milly: Love, Politics and Parkinson’s Disease and a member of the Founders' Council of the Michael J. Fox Foundation “My husband has PD, and I devoured this book. It’s wise, wonderfully readable, and, above all, helpful. Since John Vine has PD, he speaks with great authority about the challenges, both physical and psychological. If you have Parkinson’s, live with someone who has it, or just know someone battling the disease, A Parkinson’s Primer is for you.”—Lesley Stahl, award-winning television journalist on the CBS News program 60 Minutes “This is a remarkable book describing the personal experiences of many individuals, including the author, living with Parkinson’s disease. It captures the fact that although there are many possible symptoms in this disease, each person experiences different symptoms and copes with them in various ways. The thoughtful and insightful comments and coping strategies should be helpful for persons with PD, and their partners, regardless of the stage of the disease.”—Stephen Grill, MD, PhD, Director of the Parkinson’s & Movement Disorders Center of Maryland John M. Vine is a lawyer at Covington & Burling LLP in Washington, DC, where he is the senior member and former head of the firm’s employee benefits group. He was diagnosed with Parkinson’s in 2004.

    She was ten weeks pregnant with her sixth child. Her unborn baby was at risk due to the fast-spreading and highly dangerous cancer in Heather’s body that had already spread to her lymph nodes. Doctors told her she needed to abort her baby to save her life. Heather told them, “I’d rather die than take the life of my baby.” She and her husband set out to find a way to save both her and her child. The journey pushed them to the fringes of their stamina, tested the strength of their familial relationships and found them clinging to their faith like it was the last bit of thread on a lifeline. We all have unexpected adversity in life. It’s those things that we think “will never happen to us” which sneak up on us like shadows turning sunshine into darkness. It could be the loss of a job, the birth of a special needs child, the downturn of the economy or an unexpected health challenge. Most of us would easily crumble under such circumstances, but Heather found that its not about what happens to you, its about what you do with it. You don’t have to almost die, to learn how to live and Heather shows us how. Despite adversity, nearly impossible challenges can be met, families can be strengthened and faith can sustain even the most desperate souls on their journey. She brings her role as cancer-warrior into the real lives of readers, addressing topics that affect them most: • Dealing with doubt and insecurity • Discovering who they really are, and what true beauty is • Renewing their passion • Negotiating family strife • Releasing relentless regrets • Establishing a mother’s role in society • Succeeding against temptation • Weathering their worst fears • Pressing on against fatigue and illness • Uprooting bitterness • Learning to rely upon God’s will and plan Fighting for Our Lives takes readers on a journey of self-examination, appreciation for the beauties of today, and leaves them with a takeaway that could actually change their lives. *10% of this books profits will be donated to Breast Cancer Research. Thank you for helping support those in the fight! Tags: cancer memoirs, cancer memoir, cancer book, cancer books, cancer stories, cancer story, Christian memoirs, Christian memoir, Christian faith, Christian books, Christian books, memoir, memoirs, memoirs and biographies, memoir and biography, cancer memoir and biographies, cancer memoir and biography, biography, autobiography, biographies, autobiographies, faith, faith story, adversity, adversity story, adversity memoir, christian inspirational books, inspirational books, inspirational books for women, christian memoirs, christian books, memoirs, memoirs and biographies

    Integrated central case studies woven throughout each chapter, use real-life stories to give you a tangible and engaging framework around which to learn and understand the science behind environmental issues. Printed on FSC (Forest Stewardship Council) certified paper, the newly revised Fourth Edition engages you through the addition of new EnvisionIt photo essays.

    The Ketogenic Diet for Cancer fills this need. Inspired by the work of Dr. Thomas Seyfried and written by nutritionist Miriam Kalamian, this is the first book to lay out guidelines that specifically address the many challenges facing those with cancer.Kalamian, a leading voice in the keto movement, is driven by passion from her own experience in using the ketogenic diet for her young son. Her book addresses the nuts and bolts of adopting the diet, from deciding whether keto is the right choice, to developing a personal plan for smoothly navigating the keto lifestyle. It is invaluable for both beginners and seasoned users of the ketogenic diet as well as for health care professionals who need a toolkit to implement this targeted metabolic therapy.The book guides readers to a deeper understanding of the therapeutic potential of the ketogenic diet which extends well beyond simply starving cancer emphasizing the powerful impact the diet has on the metabolism of cancer cells. Nutritional nuances are explored in sections such as Fasting Protocols and Know What s in the Foods You Eat while meal templates and tracking tools are provided in Preparing Keto Meals .Kalamian also discusses important issues such as self-advocacy. Readers of The Ketogenic Diet for Cancer are empowered to get off the bench and get in the game. To that end, Kalamian offers tips on how to critically examine cancer care options then incorporate what resonates into a truly personalized treatment plan."

    He searched in vain for a book that would give him the information and advice he so desperately sought. Now this award-winning journalist has compiled just the kind of emotionally supportive and useful resource that he wished he had been able to consult-to give men the tools they need to help their wives, their families, and themselves through this scary, uncertain time.In his years as a consumer journalist and veteran of the News You Can Use staff at U.S. News & World Report, Marc Silver learned what kind of information and advice on medical crises readers found most valuable. He draws on that experience as he covers in depth all the issues couples coping with breast cancer will have to face during diagnosis, treatment, and beyond. Highlights include: - The shared experiences of other breast cancer husbands- Guidance from top cancer doctors in the country- Advice on when, how, and what to tell your young children- Tips on coping with radiation and chemotherapy - A candid discussion of sex and intimacy following breast cancer surgeryMore than 200,000 women are diagnosed with cancer each year in the United States. At last, with this book, the men who love them have a road map to help them through a difficult and unprecedented journey.

    It explains how it was a premeditated, orchestrated deception, using science to impose a political agenda. It fooled a majority including most scientists. They assumed that other scientists would not produce science for a political agenda. German Physicist and meteorologist Klaus-Eckart Puls finally decided to look for himself. Here is what he discovered. Ten years ago I simply parroted what the IPCC told us. One day I started checking the facts and data—first I started with a sense of doubt but then I became outraged when I discovered that much of what the IPCC and the media were telling us was sheer nonsense and was not even supported by any scientific facts and measurements. To this day I still feel shame that as a scientist I made presentations of their science without first checking it.…scientifically it is sheer absurdity to think we can get a nice climate by turning a CO2 adjustment knob. This book uses the same approach used in investigative journalism. It examines the Who, What, Where, When, Why, and How.

    As recently as 1918, a pandemic of influenza claimed over 50 million lives worldwide. The advent of drugs and vaccines led to an era of hope when we thought our battles with infectious disease were won, but our optimism has been eroded by the recognition that many pathogens have the capacity to transform themselves and escape our efforts to eradicate them. Are we now facing an inevitable repeat of a calamity such as the 1918 influenza pandemic or the Black Death? Can we anticipate and thwart such an event, or are we wilfully creating the conditions that would promote the emergence of new and highly virulent human infectious disease?Sunetra Gupta is Professor of Theoretical Epidemiology at the University of Oxford specialising in infectious diseases. She holds a bachelor's degree from Princeton University and a Ph.D. from the University of London. She has been awarded the Scientific Medal by the Zoological Society of London and the Royal Society Rosalind Franklin Award for her scientific research. She is also a novelist whose books have been awarded the Sahitya Akademi Award, the Southern Arts Literature Prize, shortlisted for the Crossword Award, and longlisted for the DSC and Orange Prizes.

    This volume is comprised of the years 1900 through 1959, and includes all of the best known cases of the period, as well as many more lesser-known murders, all presented in a compelling chronological narrative that takes the reader on a grisly journey through the blood-soaked avenues of early twentieth century crime. Featuring: The Peasenhall Murder. The Seal Chart Murder. The Atlanta Ripper. The Villisca Axe Murders. The Axeman of New Orleans. The Green Bicycle Case. Little Lord Fauntleroy. Hinterkaifeck Farm. The St. Aubin Street Massacre. The Wallace Case. The Atlas Vampire. The Brighton Trunk Crime. The Cleveland Torso Murderer. The Horror in Room 1046. Who Put Bella in the Wych Elm? The Pitchfork Murder. The Sodder Children. The Phantom Killer. The Black Dahlia. Somerton Man. The Grimes Sisters. The Boy in the Box. And Much More!

    But within a year she’d developed an intestinal illness so rare she wound up in a medical journal. Janet navigated misdiagnosis, multiple surgeries, and life with a permanent colostomy. Like many female patients her concerns were glossed over by doctors. She was young and insecure, major liabilities in her life as a patient. How would she advocate for low-income people when she couldn’t even advocate for herself? Janet’s model for assertiveness was her friend Beth. She was the kind of friend who’d accompany you to the doctor when you got dysentery in Ecuador, nonchalantly translating the graphic details of your symptoms into Spanish. Throughout Janet’s illness Beth took care of her; then she developed brain cancer and their roles reversed. Eventually Janet recovered, but Beth’s condition worsened. At the age of 38, Beth died. To cope, Janet competed in endurance events, becoming a triathlete with a colostomy pouch. With themes that echo Susannah Cahalan’s 'Brain on Fire' and Gail Caldwell’s 'Let’s Take the Long Way Home', GUTS is a story of resilience for the millions of Americans who manage to thrive while living with a chronic condition, as well as the many who’ve lost a loved one at a young age.