And yet she is often confounded by the cases she describes in her column: unexpected collections of symptoms that she and other physicians struggle to diagnose.A twenty-eight-year-old man, vacationing in the Bahamas for his birthday, tries some barracuda for dinner. Hours later, he collapses on the dance floor with crippling stomach pains. A middle-aged woman returns to her doctor, after visiting two days earlier with a mild rash on the back of her hands. Now the rash has turned purple and has spread across her entire body in whiplike streaks. A young elephant trainer in a traveling circus, once head-butted by a rogue zebra, is suddenly beset with splitting headaches, as if someone were "slamming a door inside his head."In each of these cases, the path to diagnosis--and treatment--is winding, sometimes frustratingly unclear. Dr. Sanders shows how making the right diagnosis requires expertise, painstaking procedure, and sometimes a little luck. Intricate, gripping, and full of twists and turns, Diagnosis puts readers in the doctor's place. It lets them see what doctors see, feel the uncertainty they feel--and experience the thrill when the puzzle is finally solved.

    When most of us study philosophy, we're focusing only on the Western intellectual tradition brought about by people such as Aristotle, Descartes, and Nietzsche. But to understand the Western intellectual tradition is to only get half of the story.Great Minds of the Eastern Intellectual Tradition is an epic, comprehensive survey of the East's most influential philosophers and thinkers. In 36 lectures, award-winning Professor Grant Hardy of the University of North Carolina at Asheville introduces you to the men and women responsible for molding Asian philosophy and for giving birth to a wide variety of spiritual and ideological systems, including Hinduism, Daoism, Confucianism, Sufism, and Buddhism. By focusing on these key thinkers in their historical contexts, you'll witness the development of these rich traditions as they shaped and defined Eastern cultures through the rise and fall of empires, the friendly and hostile encounters with each other and with the Western world, and the rapid advancements of the modern age.

    In this groundbreaking analysis, over thirty of the most popular treatments—acupuncture, homeopathy, aromatherapy, reflexology, chiropractic, and herbal medicines—are examined for their benefits and potential dangers. Questions answered include: What works and what doesn't? What are the secrets, and what are the lies? Who can you trust, and who is ripping you off? Can science decide what is best, or do the old wives' tales really tap into ancient, superior wisdom?In their scrutiny of alternative and complementary cures, authors Simon Singh and Edzard Ernst also strive to reassert the primacy of the scientific method as a means for determining public health practice and policy.

    (B) Scientific knowledge is always provisional and tells us nothing that is universal, necessary, or certain about the world. Welcome to the science wars—a long-running battle over the status of scientific knowledge that began in ancient Greece, raged furiously among scientists, social scientists, and humanists during the 1990s, and has re-emerged in today's conflict between science and religion over issues such as evolution.Professor Steven L. Goldman, whose Teaching Company course on Science in the 20th Century was praised by customers as "a scholarly achievement of the highest order" and "excellent in every way," leads you on a quest for the nature of scientific reasoning in this intellectually pathbreaking lecture series, Science Wars: What Scientists Know and How They Know It.Those who have taken Professor Goldman's previous course, which is an intensive survey of the revolution in scientific knowledge from 1900 to 2000, may have wondered: if what counts as scientific knowledge can transform so dramatically within only 100 years, what exactly is scientific knowledge? Science Wars addresses this surprisingly difficult question.Five Centuries of the Science WarsIn 24 half-hour lectures, Science Wars explores the history of competing conceptions of scientific knowledge and their implications for science and society from the onset of the Scientific Revolution in the 1600s to the present. It may seem that the accelerating pace of discoveries, inventions, and unexpected insights into nature during this period guarantees the secure foundations of scientific inquiry, but that is far from true. Consider these cases:The scientific method: In the 1600s the English philosopher Francis Bacon defined the scientific method in its classic form: the use of inductive reasoning to draw conclusions from an exhaustive body of facts. But "no scientist has ever been a strict Baconian," says Professor Goldman. "If you followed that, you would get nowhere."A "heated" debate: Around 1800 the dispute over the nature of heat was resolved in favor of the theory that heat is motion and not a substance given off during burning. But then the French mathematical physicist Joseph Fourier wrote a set of equations that accurately described how heat behaves regardless of what it "really" is, which, Fourier contended, was not a scientific question at all.Paradigm shifts: The publication in 1962 of Thomas Kuhn's The Structure of Scientific Revolutions precipitated a radical change in attitudes toward scientific knowledge, prompted by Kuhn's insight that science is not an entirely rational enterprise, and that its well-established theories (or paradigms) are overturned in a revolutionary, nonlogical process.Postmodern putdown: The postmodern attack on science as a privileged mode of inquiry made some headway in the late 20th century. But the credibility of the movement wilted in 1996, when a postmodern journal unwittingly published a spoof by physicist Alan Sokal, purporting to prove that physical theory was socially constructed. Sokal then exposed his piece as a parody.In the penultimate lecture of the course, Professor Goldman considers intelligent design—the argument that evolution can't account for the immense complexity of life and that a master designer must be at work. He approaches this topical debate by asking: What are the minimum criteria that define a hypothesis as scientific, and does intelligent design qualify? Having already covered five centuries of the science wars in the previous lectures, you will analyze this controversy with a set of tools that allows you to see the issues in a sharp, new light.What Is Reality?"Fasten your seatbelts," says Professor Goldman at the outset of Lecture 21—an advisory that applies equally to the whole course, which covers an astonishing array of ideas and thinkers. Throughout, Professor Goldman never loses his narrative thread, which begins 2,400 years ago with Plato's allegorical battle between "the gods" and "the earth giants"—between those for whom knowledge is universal, necessary, and certain; and those for whom it cannot be so and is based wholly on experience.The problem of what constitutes scientific knowledge can be illustrated with one of the most famous and widely accepted scientific theories of all time, Nicolaus Copernicus's heliostatic (stationary sun) theory of the solar system, which has undergone continual change since it was first proposed in 1543: Copernicus called for the planets to move in uniform circular motion around the sun, slightly displaced from the center. Using observations by Tycho Brahe, Johannes Kepler revised the Copernican model, discarding the ancient dogma of circular motion, which did not fit the data. Instead, he guessed that the planets in fact move in elliptical orbits. In his influential work endorsing the Copernican theory, Galileo ignored Kepler's corrections and opted for circular motion. Notoriously, the Catholic Church condemned Galileo for heresy. But the church was actually correct that he had no basis for claiming the heliocentric theory was true, rather than simply an interpretation of experience. Galileo's picture of space was superseded by Newton's and later by Einstein's, which also will doubtless be revised. Even something as basic as the elliptical motion of the planets is a vast oversimplification. There are no closed curves in space, since the solar system is moving around the center of the galaxy; the galaxy is moving within the local cluster; and the local cluster is also moving. Although we still call the conventional picture of the solar system Copernican astronomy, there is effectively no resemblance between astronomy today and Copernicus's 1543 theory of the heavens. The same is also true of other theories, such as the atomic theory of matter. All scientific theories are in a state of ceaseless revision, which raises the question of what reality "really" is. As the contemporary philosopher of science Mary Hesse has pointed out, the lesson of the history of science seems to be that the theories we currently hold to be true are as likely to be overturned as the theories they replaced!Sharpen Your Understanding of What Science IsThe uncertainty about the status of scientific knowledge and about the objectivity of the scientific enterprise led to a broad assault on science in the late 20th century by sociologists, philosophers, and historians, many connected with the postmodern movement. The lectures covering this attack and the ensuing counterattack by scientists are some of the most thrilling in the course and involve a number of figures whom Professor Goldman knows personally.Of one of the firebrands in this conflict, the late Viennese philosopher of science Paul Feyerabend, Professor Goldman says, "I myself took a seminar with Feyerabend when he was teaching at Berkeley in the early 1960s. … Feyerabend was not really off the wall, although he was often depicted that way. … He too recognized, as everyone must, that after all, science does work and science is knowledge of a sort. It's just not the absolute knowledge that scientists and philosophers have historically claimed that it is."By the time you reach the end of this course, you will understand exactly what science is, and you will be enlightened about a fascinating problem that perhaps you didn't even know existed. "There have been a raft of popular books about what scientists know," says Professor Goldman, "but to the best of my knowledge, there is not a single one of these popular books that focuses centrally on the question of how scientists know what they know."This course serves as that book.Course Lecture Titles1. Knowledge and Truth Are Age-Old Problems 2. Competing Visions of the Scientific Method 3. Galileo, the Catholic Church, and Truth 4. Isaac Newtons Theory of the Universe 5. Science vs. Philosophy in the 17th Century 6. Locke, Hume, and the Path to Skepticism 7. Kant Restores Certainty 8. Science, Society, and the Age of Reason 9. Science Comes of Age in the 19th Century 10. Theories Need Not Explain 11. Knowledge as a Product of the Active Mind 12. Trading Reality for Experience 13. Scientific Truth in the Early 20th Century 14. Two New Theories of Scientific Knowledge 15. Einstein and Bohr Redefine Reality 16. Truth, Ideology, and Thought Collectives 17. Kuhn's Revolutionary Image of Science 18. Challenging Mainstream Science from Within 19. Objectivity Under Attack 20. Scientific Knowledge as Social Construct 21. New Definitions of Objectivity 22. Science Wars of the Late 20th Century 23. Intelligent Design and the Scope of Science 24. Truth, History, and Citizenship12 Audio CDs(24 lectures, 30 minutes/lecture)

    . . If what we want in this moment is insight from this brilliant doctor about pandemics, he wants us to see that they do not occur in isolation. --Carolyn Kellogg, The Boston GlobeIn 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it?Paul Farmer, the internationally renowned doctor and anthropologist, experienced the Ebola outbreak firsthand--Partners in Health, the organization he founded, was among the international responders. In Fevers, Feuds, and Diamonds, he offers the first substantive account of this frightening, fast-moving episode and its implications. In vibrant prose, Farmer tells the harrowing stories of Ebola victims while showing why the medical response was slow and insufficient. Rebutting misleading claims about the origins of Ebola and why it spread so rapidly, he traces West Africa's chronic health failures back to centuries of exploitation and injustice. Under formal colonial rule, disease containment was a priority but care was not - and the region's health care woes worsened, with devastating consequences that Farmer traces up to the present.This thorough and hopeful narrative is a definitive work of reportage, history, and advocacy, and a crucial intervention in public-health discussions around the world.

    These individuals all lost some part of what we think of as our self, but they then offer remarkable, sometimes heart-wrenching insights into what remains. One man cut off his own leg. Another became one with the universe.We are learning about the self at a level of detail that Descartes (“I think therefore I am”) could never have imagined. Recent research into Alzheimer’s illuminates how memory creates your narrative self by using the same part of your brain for your past as for your future. But wait, those afflicted with Cotard’s syndrome think they are already dead; in a way, they believe that “I think therefore I am not.” Who—or what—can say that? Neuroscience has identified specific regions of the brain that, when they misfire, can cause the self to move back and forth between the body and a doppelgänger, or to leave the body entirely. So where in the brain, or mind, or body, is the self actually located? As Ananthaswamy elegantly reports, neuroscientists themselves now see that the elusive sense of self is both everywhere and nowhere in the human brain.

    We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    Anthony Fauci is a hero. He is anything but. As director of the National Institute of Allergy and Infectious Diseases (NIAID), Dr. Anthony Fauci dispenses $6.1 billion in annual taxpayer-provided funding for scientific research, allowing him to dictate the subject, content, and outcome of scientific health research across the globe. Fauci uses the financial clout at his disposal to wield extraordinary influence over hospitals, universities, journals, and thousands of influential doctors and scientists—whose careers and institutions he has the power to ruin, advance, or reward. During more than a year of painstaking and meticulous research, Robert F. Kennedy Jr. unearthed a shocking story that obliterates media spin on Dr. Fauci . . . and that will alarm every American—Democrat or Republican—who cares about democracy, our Constitution, and the future of our children’s health. The Real Anthony Fauci reveals how “America’s Doctor” launched his career during the early AIDS crisis by partnering with pharmaceutical companies to sabotage safe and effective off-patent therapeutic treatments for AIDS. Fauci orchestrated fraudulent studies, and then pressured US Food and Drug Administration (FDA) regulators into approving a deadly chemotherapy treatment he had good reason to know was worthless against AIDS. Fauci repeatedly violated federal laws to allow his Pharma partners to use impoverished and dark-skinned children as lab rats in deadly experiments with toxic AIDS and cancer chemotherapies. In early 2000, Fauci shook hands with Bill Gates in the library of Gates’ $147 million Seattle mansion, cementing a partnership that would aim to control an increasingly profitable $60 billion global vaccine enterprise with unlimited growth potential. Through funding leverage and carefully cultivated personal relationships with heads of state and leading media and social media institutions, the Pharma-Fauci-Gates alliance exercises dominion over global health policy. The Real Anthony Fauci details how Fauci, Gates, and their cohorts use their control of media outlets, scientific journals, key government and quasi-governmental agencies, global intelligence agencies, and influential scientists and physicians to flood the public with fearful propaganda about COVID-19 virulence and pathogenesis, and to muzzle debate and ruthlessly censor dissent.

    It promised to shed light on the deep mysteries of consciousness, as well as offer relief to addicts and the mentally ill. But in the 1960s, with the vicious backlash against the counter-culture, all further research was banned. In recent years, however, work has quietly begun again on the amazing potential of LSD, psilocybin and DMT. Could these drugs in fact improve the lives of many people? Diving deep into this extraordinary world and putting himself forward as a guinea-pig, Michael Pollan has written a remarkable history of psychedelics and a compelling portrait of the new generation of scientists fascinated by the implications of these drugs. How to Change Your Mind is a report from what could very well be the future of human consciousness.

    Cory Franklin. Filled with stories of strange medical cases and unforgettable patients culled from a thirty-year career in medicine, Cook County ICU offers readers a peek into the inner workings of a hospital. Author Dr. Cory Franklin, who headed the hospital’s intensive care unit from the 1970s through the 1990s, shares his most unique and bizarre experiences, including the deadly Chicago heat wave of 1995, treating some of the first AIDS patients in the country before the disease was diagnosed, the nurse with rare Munchausen syndrome, the first surviving ricin victim, and the famous professor whose Parkinson’s disease hid the effects of the wrong medication. Surprising, darkly humorous, heartwarming, and sometimes tragic, these stories provide a big-picture look at how the practice of medicine has changed over the years, making it an enjoyable read for patients, doctors, and anyone with an interest in medicine.

    Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family.Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life.Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

    These 24 intriguing and enlightening lectures lay bare the inner workings of our minds – and it's all brought to you by award-winning Professor Stephen P. Hinshaw, an instructor whose training as a clinical psychologist straddles both the science of the mind and its impact on individual lives. His comprehensive and unbiased approach to this subject reveals how the science of the human mind applies to the life of our species – and to your own life as well.

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    King (William and Mary University) delves into the story of how, why, where, and when we became human. These lectures will help you understand the forces that have shaped, and continue to shape, our species. "An evolutionary perspective on human behavior," notes Dr. King, "results in more than just knowledge about dates and sites when and where specific evolutionary milestones likely occurred." "It is also a window on the past and future of our species. An entirely new way of thinking comes into focus when we consider the human species within an evolutionary perspective."A Century of ScholarshipWhile covering these subjects in this 24-lecture series, Dr. King synthesizes the best that more than a century of scientific scholarship has to offer across a variety of disciplines. Biological anthropologists study primate anatomy and behavior both to understand evolution and to learn more about our common ancestor. Biological anthropologists are joined by molecular anthropologists to better understand hominids by studying fossils, ancient skeletal remains, and lifestyle information such as cave art and stone tools. Case Studies that Clarify Evolution and Its Power Dr. King begins by explaining key mechanisms through which evolution functions, citing famous and definitive case studies that demonstrate these forces. In one such landmark study, for example, biologists Peter and Rosemary Grant returned to the Galapagos Islands more than 100 years after Darwin's first voyage to conduct research on island finches. In 1977, a drought-induced scarcity of soft, edible seeds brought forth in the very next generation a population of finches with larger, stronger beaks capable of crushing larger, tougher seeds. Extraordinarily, in 1985, heavy rains produced a surplus of softer seeds, and natural selection produced a succeeding generation of the smaller-beaked variety. Evolution had occurred in two different directions within a decade. This "natural selection" is the theoretical tool of evolution, which helps us make sense of these facts. Why Evolution Remains Important to Us Today Perhaps the greatest measure of this theory's power is its relevance to our lives today. - Did you know that the gene which causes sickle cell anemia must be inherited from both parents to cause the disease but the disease does not occur when only a single gene is inherited? - Or that the single gene, in fact, affords protection from malaria? Or that race, a category so securely ingrained in our consciousness, is practically meaningless in biological terms? - Or how to evaluate the claim that a gene can be responsible for a certain personality trait? A Glimpse Into Our Selected Primate Heritage With an understanding of the basic mechanisms of evolutionary change in hand, the course looks at how our ancient primate ancestors adapted. Consider the anatomical features we share with monkeys, great apes, and other primates. Our large brains, grasping hands, and forward-facing eyes allowing us to perceive depth are critical to the way we function in the world. Yet the fossil record tells us that some 70 million years ago these distinctive primate features did not exist. What caused the first primates to emerge from existing mammalian populations? One proposed solution was that the appearance of insects living in the lower canopies of trees offered a plentiful food resource to those species adapted to procure it. Could depth perception and grasping ability have provided an advantage here, and hence been naturally selected? This is the function of biological anthropology: confronting the facts, then suggesting and testing possibilities. A Course as Much About the Present as the PastWith so much of evolutionary history taken up with the past, the insights gained in these lectures may tempt you to add questions of your own: - Is human evolution still a force in today's world? Hasn't our modern, mobile culture rendered evolution irrelevant? - In fact, human evolution is a stronger force than ever, interacting with human culture in complex ways. Issues such as obesity, AIDS, and genetics are all discussed. And you may well find these lectures opening your eyes to the extraordinary ways in which the biological power of natural selection is still at work in the world today. Course Lecture Titles1. What is Biological Anthropology? 2. How Evolution Works 3. The Debate Over Evolution 4. Matter Arising—New Species 5. Prosimians, Monkeys, and Apes 6. Monkey and Ape Social Behavior 7. The Mind of the Great Ape 8. Models for Human Ancestors? 9. Introducing the Hominids 10. Lucy and Company 11. Stones and Bones 12. Out of Africa 13. Who Were the Neandertals? 14. Did Hunting Make Us Human? 15. The Prehistory of Gender 16. Modern Human Anatomy and Behavior 17. On the Origins of Homo sapiens 18. Language 19. Do Human Races Exist? 20. Modern Human Variation 21. Body Fat, Diet, and Obesity 22. The Body and Mind Evolving 23. Tyranny of the Gene? 24. Evolution and Our Future

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.