It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    Whether it's something as minor as a brush with the common cold or as serious as Ebola, we all have grappled with infections and will continue to encounter them as we age.On a worldwide scale, infectious diseases account for 26 percent of all deaths, second only to cardiovascular diseases. And unlike chronic diseases, infectious diseases are unique in their potential for explosive global impacts.Now, in the 24 engaging lectures of Introduction to Infectious Diseases, you can get a comprehensive overview of diseases from the mundane to the fatal from renowned physician and award-winning professor Dr. Barry Fox.Begin with an overview of the microscopic particles responsible for disease: bacteria, fungi, hybrid germs, and viruses. You will see how they invade the body; look through the microscope at pathogens to identify their inner components; follow germs through to different body systems and see what effects they have; and learn why we may be losing the battle against some germs.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    One thing, however, is clear: Sleep is just as essential to life as nutrition and exercise. This course examines the latest research on the crucial phenomenon of sleep.

    They always keep a bag packed. They seldom have more than twenty-four hours' notice before they are dispatched. The phone calls that tell them to head to the airport, sometimes in the middle of the night, may give them no more information than the country they are traveling to and the epidemic they will tackle when they get there.The universal human instinct is to run from an outbreak of disease. These doctors run toward it.They are the disease detective corps of the U.S. Centers for Disease Control and Prevention (CDC), the federal agency that tracks and tries to prevent disease outbreaks and bioterrorist attacks around the world. They are formally called the Epidemic Intelligence Service (EIS) -- a group founded more than fifty years ago out of fear that the Korean War might bring the use of biological weapons -- and, like intelligence operatives in the traditional sense, they perform their work largely in anonymity. They are not household names, but over the years they were first to confront the outbreaks that became known as hantavirus, Ebola virus, and AIDS. Now they hunt down the deadly threats that dominate our headlines: West Nile virus, anthrax, and SARS.In this riveting narrative, Maryn McKenna -- the only journalist ever given full access to the EIS in its fifty-three-year history -- follows the first class of disease detectives to come to the CDC after September 11, the first to confront not just naturally occurring outbreaks but the man-made threat of bioterrorism. They are talented researchers -- many with young families -- who trade two years of low pay and extremely long hours for the chance to be part of the group that has helped eradicate smallpox, push back polio, and solve the first major outbreaks of Legionnaires' disease, toxic shock syndrome, and "E. coli" O157.Urgent, exhilarating, and compelling, "Beating Back the Devil" goes with the EIS as they try to stop epidemics -- before the epidemics stop us.

    Kasser launches an ambitious and exciting inquiry into what makes science science, using the tools of philosophy to ask: * Why is science so successful? * Is there such a thing as the scientific method? * How do we distinguish science from pseudoscience? * Is science rational, cumulative, and progressive? Focusing his investigation on the vigorous debate over the nature of science that unfolded during the past 100 years, Professor Kasser covers important philosophers such as Karl Popper, W. V. Quine, Thomas Kuhn, Paul Feyerabend, Imre Lakatos, Carl Hempel, Nelson Goodman, and Bas van Fraassen.All of these thinkers responded in one way or another to logical positivism, the dominant movement influencing the philosophy of science during the first half of the 20 th century. Logical positivism attempted to ground science exclusively in what could be known through direct experience and logic.It sounds reasonable, but logical positivism proved to be riddled with serious problems, and its eventual demise is an object lesson in how truly difficult it is—perhaps impossible—to secure the logical foundations of a subject that seems so unassailably logical: science.

    The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences?Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine.Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

    But is old age all doom and gloom?Not at all! While it's true that some functions in the aging brain decline, neuroscientists have discovered that many other brain functions remain stable - or even improve - as we age. Furthermore, nurture plays as significant a role as nature, and there are a number of strategies you can implement to stave off declining brain function, including:Incorporating physical activity into your routineEating a healthy dietMaintaining a vibrant social lifeReducing your stressThe science behind the aging brain tells a fascinating - and often counterintuitive - story. Is "aging" a disease or merely a natural occurrence that produces disease-like symptoms? If humans are biologically programmed to survive and thrive, why do we age at all? Is it possible (or even desirable) to "cure" aging altogether?Delve into these questions and more in The Aging Brain. Taught by a neuroscientist and award-winning professor at the University of Michigan, these 12 eye-opening lectures will give you a wealth of new insights into what happens to the brain over time - as well as strategies to mitigate the effects of aging and enhance your quality of life into old age.With a mix of scientific research and practical applications, Professor Polk brings cutting-edge science to life. He takes you down to the cellular and even molecular levels of the brain to show you why certain functions decline, how some aspects of brain aging are under genetic control, and what you can do to prolong your health and keep your mind sharp. Aging affects us all, but you have some control over how it affects you.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    These are today's sins of science—as deplorable as mistaken past ideas about advocating racial purity or using lobotomies as a cure for mental illness. These unwitting errors add up to seven lessons both cautionary and profound, narrated by renowned author and speaker Paul A. Offit. Offit uses these lessons to investigate how we can separate good science from bad, using some of today's most controversial creations—e-cigarettes, GMOs, drug treatments for ADHD—as case studies. For every "Aha!" moment that should have been an "Oh no," this book is an engrossing account of how science has been misused disastrously—and how we can learn to use its power for good.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.

    How many of us understand the way seizures affect the brain, how the heart is connected to wellbeing, or the why the foot carries the key to our humanity? In Adventures in Human Being, award-winning author Gavin Francis leads readers on a journey into the hidden pathways of the human body, offering a guide to its inner workings and a celebration of its marvels.Drawing on his experiences as a surgeon, ER specialist, and family physician, Francis blends stories from the clinic with episodes from medical history, philosophy, and literature to describe the body in sickness and in health, in living and in dying. At its heart, Adventures in Human Being is a meditation on what it means to be human. Poetic, eloquent, and profoundly perceptive, this book will transform the way you view your body.

    She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.

    The answer: with the essentials. Now, finally satisfy your desire for scientific inquiry in a way that makes this enormous field accessible, understandable, and undeniably captivating. Professor Viskontas boils down the scientific world into 12 key concepts every educated person should know. Devoting two lectures to each concept to give you more time to engage with it, her 24-lecture series is an engaging and enlightening introduction to everything from the behavior of subatomic particles to the latest theories about the Big Bang. Throughout, you'll get accessible looks at key building blocks of scientific knowledge, including brain plasticity, fluid mechanics, electromagnetism, genetics, quantum theory, emergence, evolution, thermodynamics, the Big Bang, and the nature of matter. Each concept is presented in a clear, concise way that will inform and delight you, and that will give you the opportunity to probe the invisible life of living cells, visit the universe seconds after its birth, and much more. Concepts that may have eluded you in school, that you may not be familiar with, or that you simply never appreciated for their intricate beauty are now brought to vivid life in a way that sticks. Welcome to the world of science - reduced to its powerful essence.