As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    These are today's sins of science—as deplorable as mistaken past ideas about advocating racial purity or using lobotomies as a cure for mental illness. These unwitting errors add up to seven lessons both cautionary and profound, narrated by renowned author and speaker Paul A. Offit. Offit uses these lessons to investigate how we can separate good science from bad, using some of today's most controversial creations—e-cigarettes, GMOs, drug treatments for ADHD—as case studies. For every "Aha!" moment that should have been an "Oh no," this book is an engrossing account of how science has been misused disastrously—and how we can learn to use its power for good.

    The Science of Evolution. From both, Richard Dawkins weaves a fascinating and beautifully illustrated account of how nature and humans have learned to overcome the pull of gravity and take to the skies.Do you sometimes dream you can fly like a bird? Gliding effortlessly above the treetops, soaring and swooping, playing and dodging through the third dimension. Computer games, virtual reality headsets, and some drugs can lift our imagination and fly us through fabled, magical spaces. But it's not the real thing. No wonder some of the past's greatest minds, including Leonardo da Vinci's, have yearned for flying machines and struggled to design them.Flights of Fancy is a book about flying – all the different ways of defying gravity that have been discovered by humans over the centuries and by other animals over the millions of years, from the mythical Icarus, to the sadly extinct but magnificent bird Argentavis magnificens, to the Wright Flyer and the 747. But it also means flights of digression into more general ideas and principles that take off from a discussion about actual flight.Fascinating and elegantly written, this is a unique collaboration between one of the world's leading zoologists and a talented artist, and perfect for enquiring teenage minds.

    But in the scalp of a balding man, they do not get everything they need and as a result, the hair-producing cells gradually die off. Here we have an example of a mild ‘disease’ which is caused by cellular malnutrition.” —Dr. Roger J. Williams “A living cell requires energy not only for all of its functions, but also for maintenance of its structure.” —Nobel Laureate Albert Szent-Györgyi "What could be more important to understand than biological energy? Thought, growth, movement, every philosophical and practical issue involves the nature of biological energy.” —Raymond Peat, PhD ======== The Current View of Pattern Hair Loss is Unproductive (and Dangerous) While it is often stated with great confidence that pattern pattern hair loss is the result of defective genes and "male" androgenic hormones (e.g., dihydrotestosterone or DHT), the theory is physiologically unsound. After 60 years of research the "genetic-androgen" hypoheses has produced a single FDA-approved "therapy" that works less than 50% the time and can result in permanent chemical castration (Minoxidil is a nonstarter for many men and women). In contrast, castrates and pseudohermaphrodites--who serve as the foundation for all baldness research--are protected from pattern hair loss 100% of the time. Steps Towards a 'Bioenergetic' View of Pattern Hair Loss Standing on the shoulders of giants (e.g., Otto Warburg, Albert Szent-Györgyi, Gilbert Ling, Ray Peat and others), HAIR LIKE A FOX sets up an alternative 'bioenergetic model' of pattern hair loss with a focus on the smallest unit of life, the cell. This same context elucidates simple yet effective therapies for halting and perhaps reversing pattern hair loss in a way that harmonizes with our unique physiology.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    From the world’s most painful hornet, to the flies that transmit deadly diseases, to millipedes that stop traffic, to the “bookworms” that devour libraries, to the Japanese beetles munching on your roses, Wicked Bugs delves into the extraordinary powers of many-legged creatures. With wit, style, and exacting research, Stewart has uncovered the most terrifying and titillating stories of bugs gone wild. It’s an A to Z of insect enemies, interspersed with sections that explore bugs with kinky sex lives (“She’s Just Not That Into You”), creatures lurking in the cupboard (“Fear No Weevil”), insects eating your tomatoes (“Gardener’s Dirty Dozen”), and phobias that feed our (sometimes) irrational responses to bugs (“Have No Fear”). Intricate and strangely beautiful etchings and drawings by Briony Morrow-Cribbs capture diabolical bugs of all shapes and sizes in this mixture of history, science, murder, and intrigue that begins—but doesn’t end—in your own backyard.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    This book is a collection of her most personal and inspirational speeches, given over the course of a year and a half, on the Obama's historic journey to the White House. In her own words, Michelle Obama talks about her beliefs, her upbringing, and her values.

    We rely on them every day of our lives. They make us who we are. And yet the truth is they are far from being the accurate record of the past we like to think they are. True, we can all admit to having suffered occasional memory lapses, such as entering a room and immediately forgetting why, or suddenly being unable to recall the name of someone we've met dozens of times. But what if our minds have the potential for more profound errors, that enable the manipulation or even outright fabrication of our memories?In The Memory Illusion, forensic psychologist and memory expert Dr Julia Shaw uses the latest research to show the astonishing variety of ways in which our brains can indeed be led astray. She shows why we can sometimes misappropriate other people's memories, subsequently believing them to be our own. She explains how police officers can imprison an innocent man for life on the basis of many denials and just one confession. She demonstrates the way radically false memories can be deliberately implanted, leading people to believe they had tea with Prince Charles, or committed crimes that never happened. And she reveals how, in spite of all this, we can improve our memory through simple awareness of its fallibility. Fascinating and unnerving in equal measure, The Memory Illusion offers a unique insight into the human brain, challenging you to question how much you can ever truly know about yourself.

    What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

    Some of their responses to those outbreaks are almost too strange to believe in hindsight. Get Well Soon delivers the gruesome, morbid details of some of the worst plagues we’ve suffered as a species, as well as stories of the heroic figures who selflessly fought to ease the suffering of their fellow man. With her signature mix of in-depth research and storytelling, and not a little dark humor, Jennifer Wright explores history’s most gripping and deadly outbreaks, and ultimately looks at the surprising ways they’ve shaped history and humanity for almost as long as anyone can remember.

    Clavell* Mail Stop by Virginia DeMarce* Those Daring Young Men by Rick Boatright* Those Daring Not So Young Men by Rick Boatright* A Matter Of Taste by Kerryn Offord* Those Not So Daring by Rick Boatright* Anna the Baptist by Terry Howard* Fly Like a Bird by Loren Jones* Gearhead by Mark H. Huston* Water Wings by Terry Howard* Under the Tuscan Son by Iver P. Cooper* Wings on the Mountain by Terry Howard* Pocket Money by John and Patti Friend* Moonraker by Karen Bergstralh* The Minstrel Boy by John Zeek* Ultralight by Sean Massey* Tool or Die by Karen Bergstralh* If at First You Don't Succeed . . . by Paula Goodlett* Waves of Change by Paula Goodlett and Gorg Huff* Try, Try Again by Paula Goodlett* Little Jammer Boys by Kim Mackey* Safe at First Base by Mark H. Huston* The Order of the Foot by Richard Evans* Trip to Paris by Kim Mackey* At the Cliff's Edge by Iver P. Cooper* A 'Merican in Moscow by Gorg Huff and Paula Goodlett* Radio in 1632, Part 3 by Rick Boatright* The Sound of Mica by Iver P. Cooper* A Tempest In a Baptistry by Terry Howard* The Daily Beer Anette Pedersen* White Gold by Kerryn Offord

    But by this point in her startling book, Dangerous Doses, readers are already on a first-name basis with the five investigators involved in breaking the case. These five -- drug inspectors, Miami detectives, and a former cop -- had marshaled their forces to protect Floridians from adulterated, expired, or mishandled prescription drugs, and Eban spent two and a half years with them, weaving together her story of drug supply corruption, not merely in Florida but throughout the nation.Americans spend nearly $216 billion to fill over 3 billion prescriptions a year, and most believe that what they ingest, inject, or apply topically travels from the drug maker to their pharmacy through pristine labs and warehouses filled with men in white coats. But Eban discovered a different route, one driven by middlemen: wholesalers who sell diverted, degraded, and expired medicine traded by felons and accompanied by falsified paperwork. The truth is chilling and complex, but Eban's intelligent writing, careful plotting, and dogged reporting make for a suspenseful and shocking read, and she offers a battle-ready road map for combating the problem, including excellent practical advice for consumers. (Fall 2005 Selection)

    In The Ends of the World, Peter Brannen dives into deep time, exploring Earth’s past dead ends, and in the process, offers us a glimpse of our possible future.Many scientists now believe that the climate shifts of the twenty-first century have analogs in these five extinctions. Using the visible clues these devastations have left behind in the fossil record, The Ends of the World takes us inside “scenes of the crime,” from South Africa to the New York Palisades, to tell the story of each extinction. Brannen examines the fossil record—which is rife with creatures like dragonflies the size of sea gulls and guillotine-mouthed fish—and introduces us to the researchers on the front lines who, using the forensic tools of modern science, are piecing together what really happened at the crime scenes of the Earth’s biggest whodunits.Part road trip, part history, and part cautionary tale, The Ends of the World takes us on a tour of the ways that our planet has clawed itself back from the grave, and casts our future in a completely new light.

     This book is a supplement to What If? and intended to enhance the experience of reading the original book. We recommend purchasing the full version of What If? on Amazon in addition to this book. Introduction What If? Serious Scientific Answers to Absurd Hypothetical Questions presents a wide variety of questions covering a range of dubious potentialities and the results which would ensue should they become reality. The questions are collected from author Randall Munroe’s website, where they are sent in by readers of his blog. Some of the questions are conceptual, for example how much force would be required for Yoda to lift an X-fighter, others are in a more serious vein. All of the answers however are based on research and the application of scientific principles by the author, himself trained in physics and a former roboticist for NASA. Benefits Spend less time reading and more time enjoying your favorite books. Discover important details you may have missed the first time. Review key concepts in an easy-to-understand and efficient manner. Use as a reference or "cheat sheet" to quickly access important information. Pick up where you left off with the original book. Focus only on critical information and eliminate unnecessary details. Buy Now Buy Now: Only $2.99 (Save $3.00 or 50%, Regular Price: $5.99) Money Back Guarantee: If you are not 100% satisfied with your purchase, simply return it to Amazon within 7 days of purchase for a full refund. Go to Your Account -> Manage Your Content and Devices -> Find the Book -> Return for Full Refund. Read Now: Your book will be delivered to your Kindle device or free Kindle software automatically.