It could forever change how you experience and interact with your physical surroundings, open your eyes to the perversity of bad design and the desirability of good design, and raise your expectations about how things should be designed.B & W photographs and illustrations throughout.

    But what would it look like to study the whole of history, from the big bang through the present day -- and even into the remote future? How would looking at the full span of time change the way we perceive the universe, the earth, and our very existence?These were the questions David Christian set out to answer when he created the field of "Big History," the most exciting new approach to understanding where we have been, where we are, and where we are going. In Origin Story, Christian takes readers on a wild ride through the entire 13.8 billion years we've come to know as "history." By focusing on defining events (thresholds), major trends, and profound questions about our origins, Christian exposes the hidden threads that tie everything together -- from the creation of the planet to the advent of agriculture, nuclear war, and beyond.With stunning insights into the origin of the universe, the beginning of life, the emergence of humans, and what the future might bring, Origin Story boldly reframes our place in the cosmos.

    Taking as territory everything from the Big Bang to the rise of civilization, Bryson seeks to understand how we got from there being nothing at all to there being us. To that end, he has attached himself to a host of the world’s most advanced (and often obsessed) archaeologists, anthropologists, and mathematicians, travelling to their offices, laboratories, and field camps. He has read (or tried to read) their books, pestered them with questions, apprenticed himself to their powerful minds. A Short History of Nearly Everything is the record of this quest, and it is a sometimes profound, sometimes funny, and always supremely clear and entertaining adventure in the realms of human knowledge, as only Bill Bryson can render it. Science has never been more involving or entertaining.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    This is the story of how these two men - separated in age by forty years - discovered the existence of the electromagnetic field and devised a radically new theory which overturned the strictly mechanical view of the world that had prevailed since Newton's time.The authors, veteran science writers with special expertise in physics and engineering, have created a lively narrative that interweaves rich biographical detail from each man's life with clear explanations of their scientific accomplishments. Faraday was an autodidact, who overcame class prejudice and a lack of mathematical training to become renowned for his acute powers of experimental observation, technological skills, and prodigious scientific imagination. James Clerk Maxwell was highly regarded as one of the most brilliant mathematical physicists of the age. He made an enormous number of advances in his own right. But when he translated Faraday's ideas into mathematical language, thus creating field theory, this unified framework of electricity, magnetism and light became the basis for much of later, 20th-century physics.Faraday's and Maxwell's collaborative efforts gave rise to many of the technological innovations we take for granted today - from electric power generation to television, and much more. Told with panache, warmth, and clarity, this captivating story of their greatest work - in which each played an equal part - and their inspiring lives will bring new appreciation to these giants of science.

    Yet, according to David Sloan Wilson, the Darwinian revolution won't be truly complete until it is applied more broadly--to everything associated with the words "human," "culture," and "policy."In a series of engaging and insightful examples--from the breeding of hens to the timing of cataract surgeries to the organization of an automobile plant--Wilson shows how an evolutionary worldview provides a practical tool kit for understanding not only genetic evolution but also the fast-paced changes that are having an impact on our world and ourselves. What emerges is an incredibly empowering argument: If we can become wise managers of evolutionary processes, we can solve the problems of our age at all scales--from the efficacy of our groups to our well-being as individuals to our stewardship of the planet Earth.

    They made the world theirs long before the rise of dinosaurs. Travelling forward into the Permian and then Triassic periods, we learn how our ancient mammal ancestors evolved from large hairy beasts with accelerating metabolisms to exploit miniaturisation, which was key to unlocking the traits that define mammals as we now know them. Elsa criss-crosses the globe to explore the sites where discoveries are being made and meet the people who make them. In Scotland, she traverses the desert dunes of prehistoric Moray, where quarry workers unearthed the footprints of Permian creatures from before the time of dinosaurs. In South Africa, she introduces us to animals, once called 'mammal-like reptiles', that gave scientists the first hints that our furry kin evolved from a lineage of egg-laying burrowers. In China, new, complete fossilised skeletons reveal mammals that were gliders, shovel-pawed Jurassic moles, and flat-tailed swimmers.This book radically reframes the narrative of our mammalian ancestors and provides a counterpoint to the stereotypes of mighty dinosaur overlords and cowering little mammals. It turns out the earliest mammals weren't just precursors, they were pioneers.

    In this lively and groundbreaking new book, economist Ian Ayres shows how today's best and brightest organizations are analyzing massive databases at lightening speed to provide greater insights into human behavior. They are the Super Crunchers. From internet sites like Google and Amazon that know your tastes better than you do, to a physician's diagnosis and your child's education, to boardrooms and government agencies, this new breed of decision makers are calling the shots. And they are delivering staggeringly accurate results. How can a football coach evaluate a player without ever seeing him play? Want to know whether the price of an airline ticket will go up or down before you buy? How can a formula outpredict wine experts in determining the best vintages? Super crunchers have the answers. In this brave new world of equation versus expertise, Ayres shows us the benefits and risks, who loses and who wins, and how super crunching can be used to help, not manipulate us.Gone are the days of solely relying on intuition to make decisions. No businessperson, consumer, or student who wants to stay ahead of the curve should make another keystroke without reading Super Crunchers.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    It's the story of a beautiful friendship between a loud, irreverent student and his soft-spoken MIT professor, of a husband and father who spent years struggling to make ends meet only to become a billionaire almost overnight with the success of Akamai Technologies, the Internet content delivery network he cofounded with his mentor. Danny Lewin's brilliant but brief life is largely unknown because, until now, those closest to him have guarded their memories and quietly mourned their loss. For Lewin was almost certainly the first victim of 9/11, stabbed to death at age 31 while trying to overpower the terrorists who would eventually fly American Flight 11 into the World Trade Center. But ironically it was 9/11 that proved the ultimate test for Lewin's vision—while phone communication failed and web traffic surged as never before, the critical news and government sites that relied on Akamai -- and the technology pioneered by Danny Lewin -- remained up and running.

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    "A stunning memoir from the astronaut who spent a record-breaking year aboard the International Space Station – a candid account of his remarkable voyage, the journeys that preceded it, and his colorful formative years." Inside book cover comments.

    From Zoroastrian sky burials to wish-granting Bolivian skulls, she investigates the world’s funerary customs and expands our sense of what it means to treat the dead with dignity. Her account questions the rituals of the American funeral industry—especially chemical embalming—and suggests that the most effective traditions are those that allow mourners to personally attend to the body of the deceased. Exquisitely illustrated by artist Landis Blair, From Here to Eternity is an adventure into the morbid unknown, a fascinating tour through the unique ways people everywhere confront mortality.

    Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human.In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome.These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.

    Weather can be deadly — especially when it strikes without warning. Millions of Americans could soon find themselves at the mercy of violent weather if the public data behind lifesaving storm alerts gets privatized for personal gain.In his first Audible Original feature, New York Times best-selling author and journalist Michael Lewis delivers hard-hitting research on not-so-random weather data — and how Washington plans to release it. He also digs deep into the lives of two scientists who revolutionized climate predictions, bringing warning systems to previously unimaginable levels of accuracy. One is Kathy Sullivan, a gifted scientist among the first women in space; the other, D.J. Patil, is a trickster-turned-mathematician and a political adviser.Most urgently, Lewis's narrative reveals the potential cost of putting a price tag on information with the potential to save lives, raising questions about balancing public service with profits in an ethically-ambiguous atmosphere.